Misc.

Jun, 2006

Transgenic mice overexpressing macrophage migration inhibitory factor (MIF) exhibit high-turnover osteoporosis

JOURNAL OF BONE AND MINERAL RESEARCH
  • Shin Onodera
  • Satoshi Sasaki
  • Shigeki Ohshima
  • Norio Amizuka
  • Minqi Li
  • Nobuyuki Udagawa
  • Kazuharu Irie
  • Jun Nishihira
  • Yoshikazu Koyama
  • Ayako Shiraishi
  • Harukazu Tohyama
  • Kazunori Yasuda
    • … Display all
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Volume
21
Number
6
First page
876
Last page
885
Language
English
Publishing type
DOI
10.1359/JBMR.060310
Publisher
WILEY
The bone phenotype of mice overexpressing MIF was studies. These mice showed decreased trabecular bone, increased bone formation rate, and increased MMP-3, -9, and -13 mRNA expression in the femora and tibias. This model provides evidence of the role played by MIF in bone remodeling and balance in vivo.
Link information
DOI
https://doi.org/10.1359/JBMR.060310
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/16753018
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000237820700008&DestApp=WOS_CPL
ID information
  • DOI : 10.1359/JBMR.060310
  • ISSN : 0884-0431
  • eISSN : 1523-4681
  • Pubmed ID : 16753018
  • Web of Science ID : WOS:000237820700008
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