MISC

2011年5月

Outcome of Regional Lymph Node Dissection in Conjunction with Laparoscopic Nephroureterectomy for Urothelial Carcinoma of the Upper Urinary Tract

JOURNAL OF ENDOUROLOGY
  • Takashige Abe
  • ,
  • Toru Harabayashi
  • ,
  • Nobuo Shinohara
  • ,
  • Ataru Sazawa
  • ,
  • Satoru Maruyama
  • ,
  • Hajime Sasaki
  • ,
  • Katsuya Nonomura

25
5
開始ページ
803
終了ページ
807
記述言語
英語
掲載種別
DOI
10.1089/end.2010.0480
出版者・発行元
MARY ANN LIEBERT INC

Objective: To obtain accurate disease staging, we routinely perform regional lymph node dissection (LND) in conjunction with laparoscopic nephroureterectomy (NU) to treat urothelial carcinoma of the upper urinary tract. The present study evaluated the feasibility and usefulness of LND in laparoscopic NU.
Patients and Methods: Thirty-nine patients undergoing laparoscopic NU with regional LND were included in the present study. We evaluated the number of lymph nodes (LNs) resected, pathological node status, adverse events, and survival data. Node count was compared with that of 41 patients who underwent open NU between 1990 and 2008.
Results: The median number of LNs removed was 10 (range, 2-59) in the laparoscopic NU group and 10 (range, 1-65) in the open NU group (Mann-Whitney U-test, p = 0.82). Pathological examination demonstrated positive LNs in four patients (10.3%) and three of the four patients received adjuvant chemotherapy. Although chylous drain discharge was detected just after resuming dietary intake in eight patients, it resolved without significant problem. Five-year overall survival by stage was 100% for pT2 >= disease, 55% for pT3 disease, and 0% for pT4 disease.
Conclusions: LND can be performed safely and effectively during laparoscopic nephroureterectmy. We consider that accurate node staging and subsequent stratification are mandatory for disease management.

Web of Science ® 被引用回数 : 10

リンク情報
DOI
https://doi.org/10.1089/end.2010.0480
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000291009700016&DestApp=WOS_CPL

エクスポート
BibTeX RIS