論文

査読有り 国際誌
2016年11月

Role of surgical consolidation in metastatic urothelial carcinoma.

Current opinion in urology
  • Takashige Abe
  • ,
  • Ryuji Matsumoto
  • ,
  • Nobuo Shinohara

26
6
開始ページ
573
終了ページ
80
記述言語
英語
掲載種別
DOI
10.1097/MOU.0000000000000329

PURPOSE OF REVIEW: Since the development of systemic combination chemotherapy, postchemotherapy extirpation has been performed in selected patients mainly with locally advanced and/or initially unresectable bladder cancer, and, in very selected patients, surgical consolidation for visceral metastases has also been performed. The purpose of this article was to review and summarize the current evidence for the role of surgical consolidation in metastatic urothelial carcinoma. RECENT FINDINGS: The role of metastasectomy has not yet been examined in a randomized setting. In terms of locally advanced and/or node-positive bladder cancer, studies further support the benefit of surgical consolidation, especially after a favorable response to systemic chemotherapy. Regarding metastasectomy for visceral metastasis, recent evidence suggested that lung metastases (ideally small solitary lesions) are a good indication. SUMMARY: Patients with a good response to chemotherapy, limited nodal/pulmonary disease, and a favorable performance status are good candidates for surgical consolidation. Careful patient selection is mandatory.

リンク情報
DOI
https://doi.org/10.1097/MOU.0000000000000329
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/27471992
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051536

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