論文

査読有り
2018年2月1日

Impact of posterior urethral diameter/external urethral sphincter diameter as a new tool to predict detrusor pressure in the voiding phase

International Urology and Nephrology
  • Masafumi Kon
  • ,
  • Takahiko Mitsui
  • ,
  • Takeya Kitta
  • ,
  • Kimihiko Moriya
  • ,
  • Nobuo Shinohara
  • ,
  • Masayuki Takeda
  • ,
  • Katsuya Nonomura

50
2
開始ページ
211
終了ページ
215
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s11255-017-1770-0
出版者・発行元
Springer Netherlands

Purposes: We measured posterior urethra diameter (PUD) and external urethral sphincter diameter (EUSD), which can also be measured by voiding cystourethrography (VCUG) and investigated the relationship between PUD/EUSD and detrusor pressure (Pdet) during voiding by videourodynamics (VUDS). Methods: Sixty-three children, who were 3 years old or less and underwent VUDS, were enrolled in the present study. We measured PUD and EUSD in addition to detrusor pressure at the time of the widest EUS during voiding (Pdet-voiding) by VUDS, and PUD/EUSD was investigated compared to Pdet-voiding. Results: Seventy-eight VUDS were performed in 63 patients, and the median age at VUDS was 10.2 months. These studies revealed a significant correlation between PUD/EUSD and Pdet-voiding (r = 0.641, p &lt
 0.001). However, a significant correlation was not observed between PUD/EUSD and age (r = 0.180). We defined Pdet-voiding of more than 80 cmH2O as a high voiding pressure, and a PUD/EUSD of 2.4 was a good predictor for the cutoff value for high voiding pressure. Pdet-voiding was significantly higher in children with a PUD/EUSD of ≥ 2.4 (p &lt
 0.001). In 19 children who had neurological diseases, a significant correlation was found between PUD/EUSD and Pdet-voiding (r = 0.842, p &lt
 0.001), and a PUD/EUSD of 2.4 was a useful cutoff value for high voiding pressure. Conclusions: PUD/EUSD is a valuable tool to predict high voiding pressure in pediatric patients. A PUD/EUSD of ≥ 2.4 in VCUG indicates the need to perform more invasive tests, such as VUDS, in pediatric patients aged 3 and under with neuropathic diseases.

リンク情報
DOI
https://doi.org/10.1007/s11255-017-1770-0
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29243203

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