1995年8月
TOTAL SYNTHESIS OF HEMIBREVETOXIN-B
TETRAHEDRON LETTERS
- ,
- ,
- ,
- ,
- ,
- 巻
- 36
- 号
- 32
- 開始ページ
- 5777
- 終了ページ
- 5780
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/0040-4039(95)01097-2
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
The total synthesis of Hemibrevetoxin B is described. A new cyclization approach, based on the Lewis acid mediated intramolecular cyclization of the gamma-oxo-substituted allylic tin having an aldehyde group, produced the 6-6-7-7 polycyclic ether skeleton of the natural product with high stereoselectivity. The H-1 and C-13-NMR spectra of synthetic hemibrevetoxin B was identical with those of natural product.
- リンク情報
- ID情報
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- DOI : 10.1016/0040-4039(95)01097-2
- ISSN : 0040-4039
- Web of Science ID : WOS:A1995RN50500031