FUKAMI Kiyoko

Last updated: Sep 7, 2019 at 17:12

Name	FUKAMI Kiyoko
Affiliation	Tokyo University of Pharmacy and Life Sciences
Section	School of Life Science, Laboratory of Genome and Biosignal
Job title	Professor
Degree	(BLANK)

Research Interests

Signal transduction(283) , Molecular biology in fertilization(1)

Research Areas

Biological science / Functional biochemistry /
Basic medicine / General medical chemistry /

Academic & Professional Experience

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1992

2002

Department of Biochemistry, Institute of Medical

2002

- Professor, Laboratory of Genome and Biosignal

1985

1992

Research Associate Department of Pharmacology,

1978

1982

Department of Pharmaceutical Experimental Lab.

and Life Science

School of Life Science, Tokyo University of Pharmacy

Science, The University of Tokyo

Tokyo Metropolitan Institute of Gerontology

Faculty of Medicine, Keio University

Education

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1978

Faculty of Pharmaceutical Science, Gifu Pharmaceutical University

Published Papers

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Cell surface CD63 increased by up-regulated polylactosamine modification sensitizes human melanoma cells to the BRAF inhibitor PLX4032

Kohya Kudo, Atsuko Yoneda, Daiki Sakiyama, Kai Kojima, Takeki Miyaji, Miku Yamazaki, Saori Yaita, Takuya Hyodo, Reiko Satow, Kiyoko Fukami

FASEB J. 33 3851-3869 2019 [Refereed]

ZIC5 drives melanoma aggressiveness by PDGFD-mediated activation of FAK and STAT3.

R. Satow, T. Nakamura, C. Kato, M. Endo, M. Tamura, R. Batori, S. Tomura, Y. Murayama, K. Fukami

Cancer Res. 77 366-377 2017 [Refereed]

Phospholipase Cd1 regulates p38 MAPK activity and skin barrier integrity.

K. Kanemaru, Y. Nakamura, K. Totoki, T. Fukuyama, M. Shoji, H. Kaneko, K. Shiratori, A. Yoneda, T. Inoue, Y. Iwakura, K. Kabashima, K. Fukami

Cell Death & Differentiation 24 1079-1090 2017 [Refereed]

Simultaneous loss of phospholipase C1 and phospholipase C3 causes cardiomyocyte apoptosis and cardiomyopathy.

Y. Nakamura, K. Kanemaru, R. Kojima, Y. Hashimoto, T. Marunouchi, N. Oka, T. Ogura, K. Tanonaka, K. Fukami

Cell Death & Disease 5 e1215 2014 [Refereed]

Phospholipase C delta 1 induces E-cadherin expression and suppresses malignancy in colorectal cancer cells.

R. Satow, T. Hirano, R. Batori, T. Nakamura, Y. Murayama, K. Fukami

Proc. Natl. Acad. Sci. USA. 111 13505-13510 2014 [Refereed]

Identification of novel small compounds that restore E-cadherin expression and inhibit tumor cell motility and invasiveness.

Hirano, R. Satow, A. Kato, M. Tamura, Y. Murayama, H. Saya, H. Kojima, T. Nagano, T. Okabe, K. Fukami

Biochem. Pharmacol. 86 1419-1429 2013 [Refereed]

Epidermal phospholipase C d1 regulates granulocyte counts and systemic interleukin-17 levels in mice.

K. Kanemaru, Y. Nakamura, K. Sato, R. Kojima, S. Takahashi, M. Yamaguchi, M. Ichinohe, H. Kiyonari, G. Shioi, K. Kabashima, K. Nakahigashi, M. Asagiri, C. Jamora, H. Yamaguchi, K. Fukami

Nature Commun. 3 963 2012 [Refereed]

Genetic defect in phospholipase Cd1 protects mice from obesity by regulating thermogenesis and adipogenesis.

M. Hirata, M. Suzuki, R. Ishii, R. Satow, T. Uchida, T. Kitazumi, T. Sasaki, T. Kitamura, H. Yamaguchi, Y. Nakamura, K. Fukami

Diabetes 60 1926-1937 2011 [Refereed]