TODA Tatsushi

J-GLOBAL         Last updated: Sep 23, 2019 at 16:30
 
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Name
TODA Tatsushi
Affiliation
The University of Tokyo
Section
Graduate School of MedicineFaculty of Medical Sciences
Job title
Professor
Degree
Doctor of Medical Science(The University of Tokyo)

Research Areas

 
 

Academic & Professional Experience

 
Aug 2017
 - 
Today
Professor, Department of Neurology, Div.of Neuroscience, The University of Tokyo
 
Apr 2009
 - 
Jul 2017
Professor, Division of Neurology, Kobe University
 
May 2000
 - 
Mar 2009
Professor, Dep.of Clinical Gene Therapy, Osaka University
 
2000
 - 
2009
Osaka University, Professor
 
2009
   
 
-   Kobe University, Professor
 
Aug 1996
 - 
Apr 2000
Assistant Professor, The Institute of Medical Science, The University of Tokyo
 
1996
 - 
2000
University of Tokyo, Assistant Professor
 
Jan 1994
 - 
Jul 1996
Assistant, Dep. of Human Genetics, The University of Tokyo
 
1994
 - 
1996
University of Tokyo, Research Assistant
 

Education

 
 
 - 
1985
Faculty of Medicine, The University of Tokyo
 

Awards & Honors

 
Jun 2017
Japan Academy Prize, The Japan Academy
 
Sep 2012
パーキンソン病および福山型筋ジストロフィー遺伝子の同定と病態解析, 平成24年度第14回時実(實)利彦記念賞, 公益信託時実利彦記念脳研究助成基金
Winner: Toda Tatsushi
 
Apr 2009
福山型筋ジストロフィーとその類縁疾患の解明に関する研究, 平成21年度文部科学大臣表彰科学技術賞, 文部科学省
Winner: Toda Tatsushi
 
Jan 2008
-, 2007 Asahi Award, -
Winner: 福山 幸夫, Toda Tatsushi, 遠藤 玉夫
 
May 2002
-, Award of Societas Neurologica Japonica, -
Winner: Toda Tatsushi
 

Published Papers

 
Ishiura H, Shibata S, Yoshimura J, Suzuki Y, Qu W, Doi K, Almansour MA, Kikuchi J, Taira M, Mitsui J, Takahashi Y, Ichikawa Y, Mano T, Iwata A, Harigaya Y, Kawabe Matsukawa M, Matsukawa T, Tanaka M, Date H, Mitsue A, Ohtomo R, Shirota Y, Kowa H, Hatsuta H, Morimoto S, Murayama S, Shiio Y, Saito Y, Sasaki T, Sugiyama Y, Hamada M, Ohtomo G, Terao Y, Nakazato Y, Takeda A, Sakiyama Y, Shibasaki K, Ogata K, Nakayama K, Kohno Y, Lim SY, Shimizu J, Goto J, Nishino I, Toda T, Morishita S, Tsuji S.
Nature Genet   51(8) 1222-1232   Aug 2019   [Refereed]
Sekiya H,Kowa H,Koga H,Takata M,Satake W,Futamura N,Funakawa I,Jinnai K,Takahashi M,Kondo T,Ueno Y,Kanagawa M,Kobayashi K,Toda T
Acta Neuropathol   137(3) 455-466   Mar 2019   [Refereed]
Uenaka T, Satake W, Cha PC, Hayakawa H, Baba K, Jiang S, Kobayashi K, Kanagawa M, Okada Y, Mochizuki H, Toda T
Hum Mol Genet   27(22) 3974-3985   Nov 2018   [Refereed]
Tsuchiya M,Hara Y,Okuda M,Itoh K,Nishioka R,Shiomi A,Nagao K,Mori M,Mori Y,Ikenouchi J,Suzuki R,Tanaka M,Ohwada T,Aoki J,Kanagawa M,Toda T,Nagata Y,Matsuda R,Takayama Y,Tominaga M,Umeda M
Nature Commun   9(1) 2049-2049   May 2018   [Refereed]
Sudo A, Kanagawa M, Kondo M, Ito C, Kobayashi K, Endo M, Minami Y, Aiba A,Toda T
Hum Mol Genet   27(7) 1174-1185   Apr 2018   [Refereed]
Kanagawa M, Kobayashi K, Tajiri M, Manya H, Kuga A, Yamaguchi Y, Akasaka-Manya K, Furukawa JI, Mizuno M, Kawakami H, Shinohara Y, Wada Y, Endo T, Toda T
Cell Reports   14(9) 2209-2223   Mar 2016   [Refereed]
Kanagawa M, Yu CC, Ito C, Fukada SI, Hozoji-Inada M, Chiyo T, Kuga A, Matsuo M, Sato K, Yamaguchi M, Ito T, Ohtsuka Y, Katanosaka Y, Miyagoe-Suzuki Y, Naruse K, Kobayashi K, Okada T, Takeda S, Toda T.
Hum Mol Genet   22(15) 3003-3015   Aug 2013   [Refereed]
Mitsui J, Matsukawa T, Ishiura H, Fukuda Y, Ichikawa Y, Date H, Ahsan B, Nakahara Y, Momose Y, Takahashi Y, Iwata A, Goto J, Yamamoto Y, Komata M, Shirahige K, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Takashima H, Kuwano R, Watanabe H, Ito M, Sobue G, Soma H, Yabe I, Sasaki H, Aoki M, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, D?rr A, Brice A, Filla A, Klockgether T, W?llner U, Nicholson G, Gilman S, Shults CW, Tanner CM, Kukull WA, Lee VM, Masliah E, Low PA, Sandroni P, Trojanowski JQ, Ozelius L, Foroud T, Tsuji S
N Engl J Med   369(3) 233-244   Jul 2013   [Refereed]
Kuga A, Kanagawa M, Sudo A, Chan YM, Tajiri M, Manya H, Kikkawa Y, Nomizu M, Kobayashi K, Endo T, Lu QL, Wada Y, Toda T
J Biol Chem   287(12) 9560-9567   Mar 2012   [Refereed]
Taniguchi-Ikeda M, Kobayashi K, Kanagawa M, Yu CC, Mori K, Oda T, Kuga A, Kurahashi H, Akman HO, DiMauro S, Kaji R, Yokota T, Takeda S, Toda T
Nature   478(7367) 127-131   Oct 2011   [Refereed]
Satake W, Nakabayashi Y, Mizuta I, Hirota Y, Ito C, Kubo M, Kawaguchi T, Tsunoda T, Watanabe M, Takeda A, Tomiyama H, Nakashima K, Hasegawa K, Obata F, Yoshikawa T, Kawakami H, Sakoda S, Yamamoto M, Hattori N, Murata M, Nakamura Y, Toda T
Nature Genet   41(12) 1303-1307   Dec 2009   [Refereed]
Sidransky E, Nalls MA, Aasly JO, Aharon-Peretz J, Annesi G, Barbosa ER, Bar-Shira A, Berg D, Bras J, Brice A, Chen CM, Clark LN, Condroyer C, De Marco EV, D?rr A, Eblan MJ, Fahn S, Farrer MJ, Fung HC, Gan-Or Z, Gasser T, Gershoni-Baruch R, Giladi N, Griffith A, Gurevich T, Januario C, Kropp P, Lang AE, Lee-Chen GJ, Lesage S, Marder K, Mata IF, Mirelman A, Mitsui J, Mizuta I, Nicoletti G, Oliveira C, Ottman R, Orr-Urtreger A, Pereira LV, Quattrone A, Rogaeva E, Rolfs A, Rosenbaum H, Rozenberg R, Samii A, Samaddar T, Schulte C, Sharma M, Singleton A, Spitz M, Tan EK, Tayebi N, Toda T, Troiano AR, Tsuji S, Wittstock M, Wolfsberg TG, Wu YR, Zabetian CP, Zhao Y, Ziegler SG
N Engl J Med   361(17) 1651-1661   Oct 2009   [Refereed]
Mitsui J, Mizuta I, Toyoda A, Ashida R, Takahashi Y, Goto J, Fukuda Y, Date H, Iwata A, Yamamoto M, Hattori N, Murata M, Toda T (corresponding author), Tsuji S
Arch (JAMA) Neurol   66(5) 571-576   May 2009   [Refereed]
Sato S, Omori Y, Katoh K, Kondo M, Kanagawa M, Miyata K, Funabiki K, Koyasu T, Kajimura N, Miyoshi T, Sawai H, Kobayashi K, Tani A, Toda T, Usukura J, Tano Y, Fujikado T, Furukawa T.
Nature Neurosci   11(8) 923-931   Aug 2008   [Refereed]
Kano H, Kurahashi H, Toda T
Proc Natl Acad Sci USA   104(48) 19034-19039   Nov 2007   [Refereed]
Nagai Y, Inui T, Popiel HA, Fujikake N, Hasegawa K, Urade Y, Goto Y, Naiki H, Toda T
Mol Biol   14(4) 332-340   Apr 2007   [Refereed]
Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms
Momose Y, Murata M, Kobayashi K, Tachikawa M, Nakabayashi Y, Kanazawa I, Toda T
Ann Neurol   51(1) 133-136   Jan 2002   [Refereed]
Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1
Yoshida A, Kobayashi K (eaqually contributed), Manya H, Taniguchi K, Kano H, Mizuno M, Inazu T, Mitsuhashi H, Takahashi S, Takeuchi M, Herrmann R, Straub V, Talim B, Voit T, Topaloglu H, Toda T (corresponding author), Endo T
Dev Cell   1 717-724   Nov 2001   [Refereed]
Localization of a gene for Fukuyama type congenital muscular dystrophy to chromosome
TODA Tatsushi
Nature Genet   5(3) 283-286   Nov 1993   [Refereed]
An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy
Kobayashi K, Nakahori Y, Miyake M, Matsumura K, Kondo-Iida E, Nomura Y, Segawa M, Yoshioka M, Saito K, Osawa M, Hamano K, Sakakihara Y, Nonaka I, Nakagome Y, Kanazawa I, Nakamura Y, Tokunaga K, Toda T
Nature   1 388-392   1998   [Refereed]

Misc

 
Ichiro Kanazawa, MD, PhD, 1941-2016
Toda Tatsushi
J Hum Genet   62(2) 133-134   Feb 2017
【パーキンソン病-基礎・臨床の最新情報-】 総論 パーキンソン病の原因遺伝子
Toda Tatsushi
日本臨床   75(1号) 21-27   Jan 2017   [Invited]
【末梢神経・筋疾患の臨床と研究】 福山型筋ジストロフィーおよび関連疾患の研究の進歩
Kanagawa Motoi, Toda Tatsushi
Medical Science Digest   42(13号) 619-622   Dec 2016   [Invited]
【小児疾患診療のための病態生理 3 改訂第5版】 筋疾患 福山型先天性筋ジストロフィー
池田真理子, Toda Tatsushi
小児内科   48(増刊) 491-500   Nov 2016   [Invited]
【神経内科疾患のtrends & topics 2017】 パーキンソン病
上田健博, Toda Tatsushi
Mebio   33(11号) 10-17   Nov 2016   [Invited]

Books etc

 
Broader Clinical Spectrum of Fukuyama congenital muscular dystrophy manifested by haplotype analysis. (共著)
New Develpments in Child Neurology(Monduzzi Ed itore)   1998   
Novel polymorphic CA repeat on the Yp11 with non-random allele distribution on sex chromosomes is a useful marker for forensic analysis. (共著)
ADVANCES IN RESEARCH ON DNA POLYMORPHISMS(TOYOSHOTEN)   1997   
Toward identification of the Fukuyama type congenital muscular dystrophy(FCMD) gene.
Congenital Muscular Dystrophies(Elsevier)   1997   
The clinical spectrum and genetic studies of Fukuyama congenital muscular dystrophy. (共著)
Congenital Muscular Dystrophies(Elsevier)   1997   
Reconfirmation of the Fukuyama congenital muscular dystrophy(FCMD) gene locus at chromosome Gq31, and a successful prenatal diagnosis of FCMD in two families. (共著)
Congenital Muscular Dystrophies(Elsevier)   1997   

Conference Activities & Talks

 
Next generation sequencing strategies and its role in identifying genetic risk factors for Parkinson's disease
TODA Tatsushi
5th World Parkinson Congress   Jun 2019   
Recent advance and molecular targeting therapy in congenital muscular dystrophy
TODA Tatsushi
Pecking University Pediatric Neurology Forum 2019   Apr 2019   
Antisense Therapy for Fukuyama Type Congenital Muscular Dystrophy and Our Recent Advance in Parkinson’s Disease
TODA Tatsushi
Chinese Academy of Medicine and Biology Institute. Kunming   Apr 2019   
Temporal requirement of dystroglycan glycosylation during brain development and rescue of severe cortical dysplasia via gene delivery in the fetal stage [Invited]
TODA Tatsushi
6th International Workshop for Glycosylation Defects in Muscular Dystrophies   Mar 2019   
Antisense Therapy for Fukuyama Type Congenital Muscular Dystrophy and Recent Advance in Dystroglycanbopathy [Invited]
TODA Tatsushi
International Joint Conference on Genetics&Medicine   Nov 2018   

Teaching Experience

 
 

Works

 
Construction of muscle specific DNA tip and its analysis
1999
Generation of a model mice for Fukuyama Type congenital muscular dystrophy
1997

Research Grants & Projects

 
Japan Agency for Medical Research and Development: Platform Program for Promotionof Genome Medicine
Project Year: Apr 2016 - Mar 2021    Investigator(s): TODA Tatsushi
Project Year: Apr 2017 - Mar 2020    Investigator(s): TODA Tatsushi
Japan Agency for Medical Research and Development: Practical Research Project for Rare/Intractable Diseases
Project Year: Apr 2017 - Mar 2020    Investigator(s): TODA Tatsushi
Japan Agency for Medical Research and Development: Practical Research Project for Rare/Intractable Diseases
Project Year: Apr 2014 - Mar 2017    Investigator(s): TODA Tatsushi
Project Year: Apr 2014 - Mar 2017    Investigator(s): TODA Tatsushi
Japan Agency for Medical Research and Development: Practical Research Project for Rare/Intractable Diseases
Project Year: Apr 2014 - Mar 2016    Investigator(s): TODA Tatsushi
Novel proteins related to long term memory
Project Year: 2002   
Identification of susceptibility genes for Parkinson's disease
Health and Labour Sciences Research Grants
Project Year: 2000   
Identification of susceptibility genes for Parkinson's disease
Grant-in-Aid for Scientific Research
Project Year: 2000   
Identification of susceptibility genes for Parkinson's disease
JST Basic Research Programs (Core Research for Evolutional Science and Technology :CREST)
Project Year: 2000   
Functional analysis of fukutin, FCMD gene product, in neuronal migration and muscular dystrophy
JST Basic Research Programs (Exploratory Research for Advanced Technology :ERATO)
Project Year: 1997   

Patents

 
特許5943466 : 福山型筋ジストロフィー治療用医薬組成物
TODA TATSUSHI, IKEDA MARIKO, KOBAYASHI KAZUHIRO