Yumi Kanegae

Profile Information

Degree: (BLANK)(The University of Tokyo)
Master of Pharmacology(Kitasato University)

J-GLOBAL ID: 200901090689072299
researchmap Member ID: 1000161627

Research Interests

Research Areas

Research History

2019 - Dec, 2022

Professor, Core Reserarch Facilities, Jikei University School of Medicine
2016 - 2019

Associate Professor, Core Research Facilities for Basic Science, Jikei University School of Medicine
2001 - 2016

The Institute of Medical Science, The University of Tokyo
1993 - 2001

東京大学医科学研究所遺伝子解析施設助手
1996 - 1998

米国The Salk Institute留学(Dr. Inder Verma)
1996 - 1998

Postdoctoral fellow Laboratory of Genetics(Dr. Inder Verma)The Salk Institute, San Diego, CA, USA
1987 - 1993

国立予防衛生研究所ウイルスリケッチア部ウイルス3室臨時職員
1984 - 1987

株式会社津村順天堂分子遺伝学研究所

Education

Committee Memberships

- Present

理事, 日本遺伝子治療学会

Major Papers

Short term but highly efficient Cas9 expression mediated by excisional system using adenovirus vector and Cre.

Sayaka Nagamoto, Miyuki Agawa, Emi Tsuchitani, Kazunori Akimoto, Saki Kondo Matsushima, Yumi Kanegae

Scientific reports, 11(1) 24369-24369, Dec 21, 2021
Acetophenone 4-nitrophenylhydrazone inhibits Hepatitis B virus replication by modulating capsid assembly.

Manabu Yamasaki, Norie Matsuda, Kazuaki Matoba, Saki Kondo, Yumi Kanegae, Izumu Saito, Akio Nomoto

Virus research, 306 198565-198565, Dec, 2021
Preferable sites and orientations of transgene inserted in the adenovirus vector genome: The E3 site may be unfavorable for transgene position

M. Suzuki, S. Kondo, Z. Pei, A. Maekawa, I. Saito, Y. Kanegae

Gene Therapy, 22(5) 421-429, May 9, 2015 Peer-reviewed

Misc.

レチノイドとB型肝炎ウイルス感染症

政木隆博, 目崎喜弘, 永森收志, 鐘ヶ江裕美, 松浦知和

ビタミン, 95(5-6) 300-301, Jun, 2021
The novel elimination system of HBV DNA using adenovirus vector expressing Cas9 and guide RNAs

A. Maekawa, Y. Kanegae

HUMAN GENE THERAPY, 28(12) A65-A65, Dec, 2017
Alfyによるメンブレントラフィック制御

蔭山俊, 和栗聡, 鐘ヶ江裕美, 曽友深, 一村義信, 斎藤泉, 福田光則, 小松雅明

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回 [2P0069]-[2P0069], Dec, 2015
Dual-safe adenovirus vector lacking virus-associated RNA genes enhanced shRNA activity

Y. Kanegae, A. Maekawa, Z. Pei, M. Suzuki, S. Kondo, I. Saito

HUMAN GENE THERAPY, 24(12) A79-A79, Dec, 2013
Very efficient production of adenovirus vector lacking genes of virus-associated RNAs that disturb cellular RNAi machinery: safer alternative to current vector

A. Maekawa, Z. Pei, M. Suzuki, S. Kondo, I. Saito, Y. Kanegae

HUMAN GENE THERAPY, 24(12) A78-A79, Dec, 2013
First-generation adenovirus vector expresses viral-associated (VA) RNAs that disturb cellular gene expressions

S. Kondo, A. Maekawa, M. Suzuki, Y. Kanegae, I. Saito

HUMAN GENE THERAPY, 24(12) A79-A79, Dec, 2013
VA RNA欠失型アデノウイルスベクターを用いたC型肝炎治療法の開発

裴崢, 史国利, 近藤小貴, 伊藤昌彦, 鐘ケ江裕美, 鈴木哲朗, 斎藤泉

日本ウイルス学会学術集会プログラム・抄録集, 60th 287, Oct 31, 2012
A role of microRNAs for sensitization to cisplatin in ovarian cancer cell lines

Saki Kondo, Yumi Kanegae, Nic Jones, Izumu Saito

HUMAN GENE THERAPY, 23(10) A96-A96, Oct, 2012
アデノウイルスベクターから発現するVA RNAがshRNAに影響を与えるか。

PEI Zheng, SHI Guoli, 近藤小貴, 伊藤昌彦, 鈴木哲朗, 斎藤泉, 鐘ケ江裕美

日本分子生物学会年会プログラム・要旨集(Web), 35th 4P-0592 (WEB ONLY), 2012
Bleomycin(BLM)肺線維症マウスに対するKeratinocyte growth factor(KGF)発現アデノウイルスベクター投与の効果

坂本聖子, 馬場靖子, 矢澤卓也, 平井豊博, 鐘ヶ江裕美, 斎藤泉, 後藤隆久, 倉橋清泰

臨床呼吸生理, 42 47-48, Jun, 2010
Construction of "Humanized" FLP Recombinases Aiming for Efficient Generation of Helper-Dependent Adenovirus Vector

Saki Kondo, Miho Terashima, Pei Zheng, Yumi Kanegae, Izumu Saito

MOLECULAR THERAPY, 17 S45-S45, May, 2009
First-generation adenovirus vectors bearing EF1A promoter do not induce host immune responses and prolong transgene expressions

Michio Nakai, Kazuo Komiya, Masashi Murata, Torn Kimura, Masaharu Kanaoka, Yumi Kanegae, Izumu Saito

JOURNAL OF GENE MEDICINE, 10(4) 451-451, Apr, 2008
Practical range of effective dose for Cre recombinase-expressing recombinant adenovirus without cell toxicity in mammalian cells

Y Baba, M Nakano, Y Yamada, Saito, I, Y Kanegae

MICROBIOLOGY AND IMMUNOLOGY, 49(6) 559-570, 2005
Production of viral vectors using recombinase-mediated cassette exchange

M Nakano, K Odaka, Y Takahashi, M Ishimura, Saito, I, Y Kanegae

NUCLEIC ACIDS RESEARCH, 33(8) e76, 2005
Practical range of effective dose for Cre recombinase-expressing recombinant adenovirus without cell toxicity in mammalian cells

Y Baba, M Nakano, Y Yamada, Saito, I, Y Kanegae

MICROBIOLOGY AND IMMUNOLOGY, 49(6) 559-570, 2005
Progress of adenovirus vector development

Y. Kanegae, M. Nakai, I. Saito

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 45(4) 549-558, 2000
Development and application of a strategy for cancer-specific and high- level expression

Y. Kanegae, S. Kondo, N. Tachikawa, I. Saito

Biotherapy, 14(6) 609-614, 2000
Reciprocal role of ERK and NF-kappa B pathways in survival and activation of osteoclasts

T Miyazaki, H Katagiri, Y Kanegae, H Takayanagi, Y Sawada, A Yamamoto, MP Pando, T Asano, IM Verma, H Oda …

JOURNAL OF CELL BIOLOGY, 148(2) 333-342, Jan, 2000
Induction of apoptosis after switch-on of the hepatitis B virus X gene mediated by the Cre/loxP recombination system

Y Shintani, H Yotsuyanagi, K Moriya, H Fujie, T Tsutsumi, Y Kanegae, S Kimura, Saito, I, K Koike

JOURNAL OF GENERAL VIROLOGY, 80 3257-3265, Dec, 1999
SDF‐1発現組換えアデノウイルス投与によるCXCR4 down modulation

池川雅哉, 田代啓, 三国貴康, 斉藤泉, 鐘ケ江裕美, 本庶佑

日本免疫学会総会・学術集会記録, 29 285-285, 1999

Books and Other Publications

ウイルスの進化:インフルエンザウイルス

新生化学実験講座, 1993

Professional Memberships

Research Projects

Study of genome editing therapy for Sly disease based on different genome editing mechanisms

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2023
Improvement of helper-dependent adenovirus vector not only increasing gene expression but also cell/tissue specificity

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2011 - 2013

KANEGAE Yumi, SAITO Izumu
Basic research on gene therapy by pulmonary epithelial cell growth factor on acute and chronic lung injury

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2006 - 2007

KURAHASHI Kiyoyasu, YAZAWA Takuya, KANEGAE Yumi, YAMADA Yoshitsugu, BABA Yasuko
Development of novel method for the construction of viral vectors using the site-specific recombinase

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2004 - 2005

KANEGAE Yumi, SAITO Izumu
がん治療をめざしたアデノウイルスベクターを用いた発現制御法の開発

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2000 - 2004

斎藤泉, 鐘ヶ江裕美, 小澤敬也, 多比良和誠, 伊庭英夫
Development of new method for construction of adenovirus vector using gene exchange reaction

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 1999 - 2000

KANEGAE Yumi, SAITO Izumu
Development of double infection method aiming at gene therapy of hepatocarcinoma.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 1997 - 1998

SAITO Izumu, KANEKO Shuich, KANEGAE Yumi
アデノウイルスベクターを用いた目的蛋白の新しい大量産生法の開発

科学研究費助成事業, 一般研究(C), 日本学術振興会, 1994 - 1994

斎藤泉, 鐘ヶ江裕美
C型肝炎ウイルスの遺伝子発現機構

科学研究費助成事業, がん特別研究, 日本学術振興会, 1993 - 1993

斎藤泉, 鐘ヶ江裕美, 原田志津子
遺伝子治療をめざしたアデノウイルスベクターの開発
Development of adenovirus vectors aiming at gene therapy.

Industrial Property Rights

特許第4153607号新規な組換えアデノウイルス

斎藤泉, 鐘ケ江裕美
特開2000-152781 新規な組換えアデノウイルス

斎藤泉, 鐘ケ江裕美

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Major Papers

Misc.

Books and Other Publications

Professional Memberships

Research Projects

Industrial Property Rights

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