上阪等 (Hitoshi Kohsaka) - マイポータル - researchmap

基本情報

所属: 東京医科歯科大学大学院医歯学総合研究科生体環境応答学系専攻生体応答学講座助教授・准教授

学位: 医学博士(東京医科歯科大学)

J-GLOBAL ID: 200901003688278985
researchmap会員ID: 1000161719

外部リンク: http://www.tmd.ac.jp/grad/rheu/rheu-J.htm

研究キーワード

2

研究分野

1

ライフサイエンス / 膠原病、アレルギー内科学 /

委員歴

3

受賞

4

MISC

36

Abundant expression of common Cytokine receptor γ chain(CD132)in the rheumatoid joints(共著)

Journal of Rheumatology 28(2) 240-244 2001年
Adenoviral transfer of cyclin-dependent kinase inhibitor genes suppresses collagen-induced arthritis in mice

K Nasu, H Kohsaka, Y Nonomura, Y Terada, H Ito, K Hirokawa, N Miyasaka

JOURNAL OF IMMUNOLOGY 165(12) 7246-7252 2000年12月
Gene therapy for arthritis

Modern Rheumatology 10(2) 78-82 2000年
Induction of the p16(INK4a) senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis

K Taniguchi, H Kohsaka, N Inoue, Y Terada, H Ito, K Hirokawa, N Miyasaka

NATURE MEDICINE 5(7) 760-767 1999年7月
High dose chemotherapy and syngeneic haematopoietic progenitor cell transplantation for severe, seronegative rheumatoid arthritis

Annals of Internal Medicine 131 507-509 1999年
CrKL activates integrin-mediated hematopoietic cell adhesion through a guanine nucleotide exchange factor C3G(共著)

Blood 93(11) 3713-3722 1999年
Severe Anemia due to Hemorrhagic Gastritis Associated with Sj(]E88DB[)gren's Syndrome (共著)

Clinical and Experimental Rheumatology 16(1) 105 1998年
Formation of Peripheral Immunoreceptor Repertoire for Antigens ; Potential Relationship to the Pathogenesis of Rheumatoid Arthritis

Arthritis and Rheumatism 41(11) 1911 1998年
A Mediator of Interleukin-1, Tumor Necrosis Factor-α, as well as Fas Receptor Signaling Induces Apoptosis of Rheumatoid Synovial Cells

Annals of Rheumatic Diseases 57(8) 495 1998年
Development of human peripheral T cell receptor BJ gene repertoire

Journal of Immunology 161(1) 228 1998年
HLA dependent pevipheral T cell repertoire formation and its modification by rheumatoid arthritis. (共著)

Clinical and Experimental Immunology 110(3) 428 1997年
Evidence for self and non-self-peptide agonists that prolong clonal survival of mature T cells in vitro. (共著)

Journal of Immunology 158 5685 1997年
Double-negative BV8S3 T cells expanded in MRL lpr/lpr lymph nodes conserve TCRBJ gene usage of single-positive BV8S3 T cells

J Fan, T Nanki, N Miyasaka, H Kohsaka

MICROBIOLOGY AND IMMUNOLOGY 41(3) 253-260 1997年
Diversity of a human CD4(+) T cell repertoire recognizing one TCR ligand

S Matsushita, H Yokomizo, H Kohsaka, Y Nishimura

IMMUNOLOGY LETTERS 51(3) 191-194 1996年7月
Shared amino acid motifs in T-cell receptor beta junctional regions of bronchoalveolar T cells in patients with pulmonary sarcoidosis

Y Usui, H Kohsaka, Y Eishi, Saito, I, F Marumo, N Miyasaka

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 154(1) 50-56 1996年7月
The Human immunoglobulin VH gene repertoire is genetically controlled and unaltered by chronic autoimmune stimulation

Journal of Clinacal Investigation 98(12) 2794-800 1996年
Genetic control of human TCRBJ gene repertoires of peripheral T lymphocytes of normal and rheumatoid arthritis monozygotic twins (共著)

Jouranal of Clinacal Investigation 98(7) 1594-1601 1996年
Ceramide induces apoptosis via CPP32 activation (共著)

FEBS Letters 395(2/3) 267-271 1996年
Influence of the rheumatoid arthritis associated shared epitope on T cell receptor repertoire formation

Proceedings of Amerian Academy of Physicians 108(9) 323-328 1996年
The costimulatory mdecules CD86(B7-2,B70) and CD28 are present in rheumatoid arthritis synovia (共著)

Arthritis and Rheumatism 9 110-114 1996年

もっとみる

所属学協会

6

Works(作品等)

2

慢性関節リウマチ遺伝子治療に関する研究

2000年 - 2001年
Gene therapy of rheumatoid arthritis

2000年 - 2001年

共同研究・競争的資金等の研究課題

8