OKADA Yasunobu

J-GLOBAL         Last updated: Jun 14, 2019 at 15:16
OKADA Yasunobu
National Institute for Physiological Sciences
Job title
Emeritus Professor
Other affiliation
Kyoto Prefectural University of Medicine

Research Interests


Research Areas


Published Papers

Tweety homologs (TTYH) freshly join the journey of molecular identification of the VRAC/VSOR channel pore
OKADA Yasunobu
Experimental Neurobiology   28(2) 131-133   Apr 2019   [Invited]
Roles of volume-regulatory anion channels, VSOR and Maxi-Cl, in apoptosis, cisplatin resistance, necrosis, ischemic cell death, stroke and myocardial infarction.
Y. Okada, T. Numata, K. Sato-Numata, R.Z. Sabirov, H. Liu, S. Mori & S. Morishima
Curr. Top. Membr.   83 205-283   Jun 2019   [Refereed][Invited]
Cell volume-activated and -correlated anion channels in mammalian cells: Their biophysical, molecular and pharmacological properties.
Y. Okada, T. Okada, K. Sato-Numata, Md. R. Islam, Y. Ando-Akatsuka, T. Numata, M. Kubo, T. Shimizu, R.S. Kurbannazarova, Y. Marunaka & R.Z. Sabirov
Pharmacol. Rev.   71 49-88   Jan 2019   [Refereed][Invited]
Numata T, Sato-Numata K, Okada Y, Inoue R
Journal of natural medicines   72(3) 694-705   Jun 2018   [Refereed]
Okada Y, Okada T, Islam MR, Sabirov RZ
Current topics in membranes   81 125-176   2018   [Refereed][Invited]
Sabirov RZ, Merzlyak PG, Okada T, Islam MR, Uramoto H, Mori T, Makino Y, Matsuura H, Xie Y, Okada Y
The EMBO journal   36(22) 3309-3324   Nov 2017   [Refereed]
Okada T, Islam MR, Tsiferova NA, Okada Y, Sabirov RZ
Channels (Austin, Tex.)   11(2) 109-120   Mar 2017   [Refereed]
Sato-Numata K, Numata T, Inoue R, Sabirov RZ, Okada Y
Channels (Austin, Tex.)   11(2) 167-172   Mar 2017   [Refereed]
Sato-Numata K, Numata T, Inoue R, Okada Y
Pflugers Archiv : European journal of physiology   468(5) 795-803   May 2016   [Refereed]
Okada Y
The Journal of physiology   594(6) 1523-1524   Mar 2016   [Refereed]
Pedersen SF, Okada Y, Nilius B
Pflugers Archiv : European journal of physiology   468(3) 371-383   Mar 2016   [Refereed][Invited]
Sabirov RZ, Merzlyak PG, Islam MR, Okada T, Okada Y
Pflugers Archiv : European journal of physiology   468(3) 405-420   Mar 2016   [Refereed][Invited]
Characteristics and roles of the volume-sensitive outwardly rectifying (VSOR) anion channel in the central nervous system.
T. Akita & Y. Okada
Neuroscience   275 211-231   2014   [Refereed]
Okada T, Akita T, Sato-Numata K, Islam MR, Okada Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology   33(3) 539-556   2014   [Refereed]
Temperature sensitivity of acid-sensitive outwardly rectifying (ASOR) anion channels in cortical neurons is involved in hypothermic neuroprotection against acidotoxic necrosis.
Sato-Numata K, Numata T, Okada Y
Channels (Austin, Tex.)   8(3) 278-283   2014   [Refereed]
Sato-Numata K, Numata T, Okada T, Okada Y
Pflugers Archiv : European journal of physiology   465(11) 1535-1543   Nov 2013   [Refereed]
R.Z. Sabirov, R.S. Kurbannazarova, N.R. Melanova & Y. Okada
PLoS One   8(1) e55646   2013   [Refereed]
T. Shimizu, T. Iehara, K. Sato, T. Fujii, H. Sakai & Y. Okada
Am. J. Physiol. Cell Physiol.   304 C748-C759   2013   [Refereed]
Protective role of cardiac CFTR activation upon early reperfusion against myocardial infarction.
H. Uramoto, T. Okada & Y. Okada
Cell. Physiol. Biochem.   30 1023-1038   2012   [Refereed]
T. Numata, K. Sato, J. Christmann, R. Marx, Y. Mori, Y. Okada & F. Wehner
J Physiol (London)   590 1121-1138   2012   [Refereed]
Y. Ando-Akatsuka, T. Shimizu, T. Numata & Y. Okada
J Cell Physiol   227 3498-3510   2012   [Refereed]
K. Dezaki, E. Maeno, K. Sato, T. Akita & Y. Okada
Apoptosis   17 821-831   2012   [Refereed]
M. R. Islam, H. Uramoto, T. Okada, R.Z. Sabirov & Y. Okada
Am. J. Physiol. Cell Physiol.   303 C924-C935   2012   [Refereed]
Y. Hasegawa, T. Shimizu, N. Takahashi & Y. Okada
Int. J. Mol. Sci.   13 9363-9379   2012   [Refereed]
Apoptotic volume decrease (AVD) is independent of mitochondrial dysfunction and initiator caspase activation.
E. Maeno, T. Tsubata & Y. Okada
Cells   1 1156-1167   2012   [Refereed]
S. Kaori, T. Numata, T. Saito, Y. Ueta & Y. Okada
Science Signaling   4(157) ra5   2011   [Refereed]
O.V. Krasilnikov, R.Z. Sabirov & Y. Okada
J. Physiol. Sci.   61(4) 267-278   2011   [Refereed]
R.S. Kurbannazarova, S.V. Bessonova, Y. Okada & R.Z. Sabirov
Int. J. Mol. Sci.   12 9125-9137   2011   [Refereed]
Endogenous arginine vasopressin-positive retinal cells in arginine vasopressin-eGFP transgenic rats identified by immunohistochemistry and reverse transcriptase-polymerase chain reaction.
S. Moritoh, K. Sato, Y. Okada & A. Koizumi
Molecular Vision   17 3254-3261   2011   [Refereed]
A.F. James, R.Z Sabirov, Y. Okada
Biochem. Biophys. Res. Commun.   391(1) 841-845   2010   [Refereed]
M. Subramanyam, N. Takahashi, Y. Hasegawa, T. Mohri & Y. Okada
J. Biol. Chem.   285(9) 6109-6117   2010   [Refereed]
H. Inoue, N. Takahashi, Y. Okada & M. Konishi
Am. J. Physiol. Cell Physiol.   298 C900-C909   2010   [Refereed]
Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus
T. Ohbuchi, K. Sato, H. Suzuki, Y. Okada, G. Dayanithi, D. Murphy & Y. Ueta
J. Physiol. (London)   588 2147-2162   2010   [Refereed]
Sabirov RZ, Okada Y
J. Physiol. Sci.   59 3–21   2009   [Refereed]
Okada Y, Sato K, Numata T
J. Physiol. (London)   587 2141-2149   2009   [Refereed]
A.H. Toychiev, R.Z. Sabirov, N. Takahashi, Y. Ando-Akatsuka, H.-T. Liu, T. Shintani, M. Noda & Y. Okada
Am. J. Physiol. Cell Physiol.   297 C990-C1000   2009   [Refereed]
Liu HT, Akita T, Shimizu T, Sabirov RZ, Okada Y
J. Physiol. (London)   587 2197-2209   2009   [Refereed]
Volume-sensitive Cl- channel as a regulator of acquired cisplatin resistance.
Shimizu T, Lee EL, Okada Y
Anticancer Res.   28 75-84   2008   [Refereed]
Liu HT, Sabirov RZ, Okada Y
Purinergic Signalling   4 147-154   2008   [Refereed]
NUMATA Tomacohiro, OKADA Yasunobu
J. Biol. Chem.   283(22) 15097-15103   2008   [Refereed]
Lee EL, Hasegawa Y, Shimizu T, Okada Y
Am. J. Physiol. Cell Physiol.   294 C1398 - C1406   2008   [Refereed]
NUMATA Tomohiro, SATO Kaori, OKADA Yasunobu, WEHNER Frank
Apoptosis   13(7) 895-903   2008   [Refereed]
Numata T, Okada Y
Channels   2 283-286   2008   [Refereed]
Numata T, Shimizu T, Okada Y
Am. J. Physiol. Cell Physiol   292 C460-C467   2007   [Refereed]
Numata T, Shimizu T, Okada Y
Cell. Physiol. Biochem.   19 1-8   2007   [Refereed]
Impaired activity of volume-sensitive Cl- channel is involved in cisplatin resistance of cancer cells.
J. Cell. Physiol.   211(2) 513-521   2007   [Refereed]
Wang HY, Shimizu T, Numata T, Okada Y
Pflügers Arch. Eur. J. Physiol.   454 223-233   2007   [Refereed]
Inoue H, Okada Y
J. Neurosci.   27 1445-1455   2007   [Refereed]
Wehner F, Numata T, Subramaniam M, Takahashi N, Okada Y
Cell. Physiol. Biochem.   20 75-82   2007   [Refereed]
Inoue H, Ohtaki H, Nakamachi T, Shioda S, Okada Y
J. Neurosci. Res.   85 1427-1435   2007   [Refereed]
Numata T, Wehner F, Okada Y
J. Physiol. Sci.   57(4) 249-252   2007   [Refereed]
ZAMARAEVA Maria V., ZAMARAEVA Maria V., SABIROV Ravshan Z., SABIROV Ravshan Z., MANABE Ken−ichi, OKADA Yasunobu
Biochem. Biophys. Res. Commun.   363(3) 687-693   2007   [Refereed]
Prerequisite role of persistent cell shrinkage in apoptosis of human epithelial cells
Shimizu T, Maeno E, Okada Y
Acta Physiologica Sinica   59 512-526   2007   [Refereed][Invited]
Yasunobu Okada, Yasunobu Okada
Contributions to Nephrology   152 9-24   Nov 2006
Cell volume regulation is essential for the survival of cells. After osmotic swelling, animal cells show a regulatory volume decrease by releasing intracellular K+, Cl- and water. In most cell types, volume-regulatory Cl- efflux is induced by acti...
Yasunobu Okada
Journal of Membrane Biology   209 1-2   Jan 2006
Okada Y, Shimizu T, Maeno E, Tanabe S, Wang X, Takahashi N
J. Membrane Biol.   209 21-29   2006   [Refereed][Invited]
SABIROV Ravshan Z., SHEIKO Tatiana, LIU Hongtao, DENG Defeng, OKADA Yasunobu, CRAIGEN William J.
J. Biol. Chem.   281(4) 1897-1904   2006   [Refereed]
Maeno E, Shimizu T, Okada Y
Acta Physiologica   187 217-222   2006   [Refereed]
Liu HT, Tashmukhamedov BA, Inoue H, Okada Y, Sabirov RZ
Glia   54 343-357   2006   [Refereed]
Nukui M, Shimizu T, Okada Y
J. Physiol. Sci.   56(5) 335-339   2006   [Refereed]
Shimizu T, Wehner F, Okada Y
Cell. Physiol. Biochem.   18 295-302   2006   [Refereed]
MAENO Emi, TAKAHASHI Nobuyuki, OKADA Yasunobu
FEBS Lett.   580(27) 6513-6517   2006   [Refereed]
Ravshan Z. Sabirov, Yasunobu Okada
Purinergic Signalling   1 311-328   Dec 2005
ATP serves not only as an energy source for all cell types but as an 'extracellular messenger' for autocrine and paracrine signalling. It is released from the cell via several different purinergic signal efflux pathways. ATP and its Mg2+ and/or H+...
FEBS Lett.   579(2) 517-522   2005   [Refereed]
Inoue H, Mori S, Morishima S, Okada Y
Eur. J. Neurosci.   21 1648-1658   2005   [Refereed]
M.V. Zamaraeva, R.Z. Sabirov, E. Maeno, Y. Ando-Akatsuka, S.V. Bessonova & Y. Okada
Cell Death & Differentiation   12 1390-1397   2005   [Refereed]
Y. Okamura, A. Nishino, Y. Murata, K. Nakajo, H. Iwasaki, Y. Ohtsuka, M. Tanaka-Kunishima, N. Takahashi, Y. Hara, T. Yoshida, M. Nishida, H. Okado, H. Watari, I. A. Meinertzhagen, N. Satoh, K. Takahashi, Y. Satou, Y. Okada & Y. Mori
Physiolog. Genomics   22 269-282   2005   [Refereed]
X. Wang, N. Takahashi, H. Uramoto & Y. Okada
Cell. Physiol. Biochem.   16 147-154   2005   [Refereed]
T. Ise, T. Shimizu, E.L. Lee, H. Inoue, K. Kohno & Y. Okada
J. Membrane Biol.   205 139-145   2005   [Refereed]
H. Kida, T. Miyoshi, K. Manabe, N. Takahashi, T. Konno, S. Ueda, T. Chiba, T. Shimizu, Y. Okada & S. Morishima
J. Membrane Biol.   208 55-64   2005   [Refereed]
J. Wang, H. Xu, S. Morishima, S. Tanabe, K. Jishage, S. Uchida, S. Sasaki, Y. Okada & T. Shimizu
Jpn. J. Physiol.   55(6) 379-383   2005   [Refereed]
Takahashi S, Wang XM, Tanabe S, Uramoto H, Jishage K, Uchida S, Sasaki S, Okada Y
Cell. Physiol. Biochem.   15 263-270   2005   [Refereed]
Anion channel involved in induction of apoptosis and necrosis.
Y. Okada, E. Maeno & S. Mori
Adv. Exp. Med. Biol.   559 205-209   2004   [Refereed][Invited]
R.Z. Sabirov & Y. Okada
Jpn. J. Physiol.   54(1) 7-14   2004   [Refereed]
Y. Okada, E. Maeno, T. Shimizu, K. Manabe, S. Mori & T. Nabekura
Pflügers Arch. Eur. J. Physiol.   448 287-295   2004   [Refereed][Invited]
Okada Y
Cell Biochem. Biophys.   41 233-258   2004   [Refereed][Invited]
Expression of novel isoforms of the ClC-1 chloride channel in astrocytic glial cells in vitro.
X.-D. Zhang, S. Morishima, Y. Ando-Akatsuka, N. Takahashi, T. Nabekura, H. Inoue, T. Shimizu & Y. Okada
Glia   47 46-57   2004   [Refereed]
W. Gong, H. Xu, T. Shimizu, S. Morishima, S. Tanabe, T. Tachibe, S. Uchida, S. Sasaki & Y. Okada
Cell. Physiol. Biochem.   14 213-224   2004   [Refereed]
Proc. Natl. Acad. Sci. USA   101(17) 6770-6773   2004   [Refereed]
R.Z. Sabirov & Y. Okada
Biophys. J.   87 1672-1685   2004   [Refereed]
K. Manabe, T. Shimizu, S. Morishima & Y. Okada
Pflügers Arch. Eur. J. Physiol.   448 596-604   2004   [Refereed]
A.K. Dutta, R.Z. Sabirov, H. Uramoto & Y. Okada
J. Physiol. (London)   559 799-812   2004   [Refereed]
FEBS Lett.   576(3) 433-436   2004   [Refereed]
Detecting ATP release by a biosensor method.
S. Hayashi, A. Hazama, A. K. Dutta, R. Z. Sabirov & Y. Okada
Science’s STKE   2004-258: (p1-14) 1-12   2004   [Refereed]
Protective role of cardiac CFTR activation upon early reperfusion against myocardial infarction.
H. Uramoto, T. Okada & Y. Okada
Cell. Physiol. Biochem.   30 1023-1038   2003   [Refereed]
IK channels are involved in the regulatory volume decrease in human epithelial cells.
J. Wang, S. Morishima & Y. Okada
Am. J. Physiol.   284 C77-C84   2003   [Refereed]
T. Nabekura, S. Morishima, T.L. Cover, S. Mori, H. Kannan, S. Komune & Y. Okada
Glia   41 247-259   2003   [Refereed]
Proc. Natl. Acad. Sci. USA   100(7) 4322-4327   2003   [Refereed]
L.F. Barros, T. Kanaseki, R. Sabirov, S. Morishima, J. Castro, C.X. Bittner, E. Maeno, Y. Ando-Akatsuka & Y. Okada
Cell Death & Differentiation   10 687-697   2003   [Refereed]
I.F. Abdullaev, R.Z. Sabirov & Y. Okada
J. Physiol. (London)   549 749-758   2003   [Refereed]
Calcium-activated non-selective cation channel in macula densa cells.
J.-Y. Lapointe, P.D. Bell, R.Z. Sabirov & Y. Okada
Am. J. Physiol.   285 F275-F280   2003   [Refereed]
FEBS Lett.   551(1/3) 20-24   2003   [Refereed]
Evaluation of neuronal cell death after a new global ischemia model in infant mice.
H. Ohtaki, S. Mori, T. Nakamachi, K. Dohi, L. Yin, S. Endo, Y. Okada & S. Shioda
Acta Neurochir. Suppl.   86 97-100   2003   [Refereed]
H. Uramoto, N. Takahashi, A.K. Dutta, R.Z. Sabirov, Y. Ando-Akatsuka, S. Morishima & Y. Okada
Jpn. J. Physiol.   53(5) 357-365   2003   [Refereed]
Y. Hara, M. Wakamori, M. Ishii, E. Maeno, M. Nishida, T. Yoshida, H. Yamada, S. Shimizu, E. Mori, J. Kudoh, N. Shimizu, H. Kurose, Y. Okada, K. Imoto & Y. Mori
Molecular Cell   9 163-173   2002   [Refereed]
Two-photon excitation fluorescence imaging of the living juxtaglomerular apparatus.
J. Peti-Peterdi, S. Morishima, P.D. Bell & Y. Okada
Am. J. Physiol.   283 F197-F201   2002   [Refereed]
S.-S. Zhou, A. Takai & Y. Okada
Pflügers Arch. Eur. J. Physiol.   444 327-334   2002   [Refereed]
A.K. Dutta, Y. Okada & R.Z. Sabirov
J. Physiol. (London)   542 803-816   2002   [Refereed]


Ca┣D12+┫D1 sensitivity of volume-regulatory K┣D1+┫D1 and Cl┣D1-┫D1 Channels in cultured human epithelial cells.
Journal of Physiology (London)   (402) 687   1988
Volume-regulatory Cl┣D1-┫D1 channel currents in cultured human epithelial cells.
Journal of Physiology (London)   (456) 351   1992
Membrane capacitance increases induced by histamine and cyclic AMP in single gastric acid-secreting cells of guinea pig.
Pflugers Archiv   (422) 84   1992
Solute transport process in intestinal epithelial cells.
Membrane Biochemistry   (2) 339   1979
Oscillations of membrane potential in L cells.
Journal of Membrane Biology   (35) 319   1977
Electrical properties and active solute transport in rat small intestine.
Journal of Membrane Biology   (31) 205   1977
Electric pulse-induced fusion of mouse lymphoma cells.
Journal of Membrane Biology   (85) 269   1985
Disopyramide blocks pancreatic ATP -sensitive K┣D1+┫D1 channels and enhances insulin release.
American Journal of Physiology   (265) C377   1993
Glucose sensitivity of ATP-sensitive K┣D1+┫D1 channels is impaired in β cells of the GK rat, a new genetic model of NIDDM.
Diabetes   (42) 1446   1993
Maxi-K┣D1+┫D1 channels from the apical membranes of rabbit oviduct epithelial cells.
Journal of Membrane Biology   137 109   1994
Voltage-and time-dependent K┣D1+┫D1 channel currents in the basolateral membrane of villus enterocytes isolated from guinea pig small intestine.
Journal of General Physiology   103 429   1994
Histamine modulates three types of K┣D1+┫D1 current in a human intestinal epithelial cell line.
Pflugers Archiv   428 468   1994
Yasunobu OKADA, Carl C. H. PETERSEN, Machiko KUBO, Shigeru MORISHIMA, Makoto TOMINAGA
Japanese Journal of Physiology   44(4) 403-409   1994
Glibenclamide, and ATP-sensitive K┣D1+┫D1 channel blocker, inhibits the cardiac cyclic AMP-activated Cl┣D1-┫D1 conductance
Circulation Research   77 417   1995
A mini-Cl┣D1-┫D1 channel sensitive to external pH in the basolateral membrane of guinea pig parietal cells
Journal of Physiology (London)   488 57   1995
A maxi-Cl┣D1-┫D1 channel coupled to endothelin-B receptors in the basolaternal membrane of guirea pig partetal cells
Journal of Physiology (London)   488 65   1995
Sensitivty of volume-sensitive Cl┣D1-┫D1 conductance in human epithelial cells to extracellular nucleotides.
American Jonrnal of physiology   271 C1872   1996
Volume expansion-sensing outward rectifier Cl┣D1-┫D1 channel : Fresh start to the molecular identity and volume sensor.
American Journal of Physiology   (273) C755   1997
Phosphatase-mediated enhancement of cardiac cAMP-activated Cl┣D1-┫D1 conductance bya Cl┣D1-┫D1 channel blocker, anthracene-9-carboxylate
Circulation Research   81 219   1997
Glibenclamide blocks volume-sensitive Cl┣D1-┫D1 channels by dual mechamisms.
American Journal of Physiology   275 C343   1998
Swelling-activated, cystic firosis transmembrane conductance regulator-augmented ATP release and Cl┣D1-┫D1 conductance in C127 cells
Journal of Physiology (London)   523 1   2000

Books etc

Patch Clamp Techniques - From Beginning to Advanced Protocols
Y. Okada (ed.)
Springer   2012   
Ion channel pore sizing in patch-clamp experiments. In,“Patch Clamp Techniques - From Beginning to Advanced Protocols” (ed. Y. Okada)
R.Z. Sabirov & Y. Okada (Part:Contributor, pp389-402)
Springer   2012   
Smart-patch technique. In,“Patch Clamp Techniques - From Beginning to Advanced Protocols” (ed. Y. Okada)
R.Z. Sabirov, Y.E. Korchev & Y. Okada (Part:Contributor, pp389-402)
Springer   2012   
パッチクランプ法によるチャネルポアサイズ計測法. “最新パッチクランプ実験技術法”(岡田泰伸 編
サビロブ ラブシャン、岡田泰伸
吉岡書店   2011   
スマートパッチ法. “最新パッチクランプ実験技術法”(岡田泰伸 編)
サビロブ ラブシャン、コルシェフ ユーリ、岡田泰伸
吉岡書店   2011   
パッチクランプ法総論. “最新パッチクランプ実験技術法”(岡田泰伸 編)
吉岡書店   2011   
ギャノング 生理学(原書23版)
OKADA Yasunobu
丸善   2011   
脳科学の未来 “解き明かされる脳の不思議”(立花 隆 編)
立花 隆、岡田泰伸
クバプロ   2009   
第一章 細胞の一般生理.“標準生理学”(第7版)(小澤瀞司、福田康一郎 総編集)pp10-46
医学書院   2009   
Patch-clamp techniques: General remarks.  In,“Patch Clamp Techniques - From Beginning to Advanced Protocols” (ed. Y. Okada)
T. Akita, M. Ohara & Y. Okada (Part:Contributor, pp389-402)
Springer   2009   
The puzzles of volume-activated anion channels. In, “Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases” (eds. F.J. Alvarez-Leefmans & E. Delpire) pp 283-306
Y. Okada, K. Sato, A.H. Toychiev, M. Suzuki, A.K. Dutta, H. Inoue & R.Z. Sabirov (Part:Contributor, pp 145-146)
Elsevier, San Diego   2009   
細胞内の水の調節 “水とからだの事典”(佐々木成、石橋賢一 編)
朝倉書店   2008   
パッチクランプ法-イオンフローの解析- “実験医学別冊 実験ハンドブックシリーズ “生命科学のための機器分析実験ハンドブック”(西村善文 編)
羊土社   2007   
ギャノング 生理学(原書22版)
丸善   2006   
細胞とその環境.“標準生理学 (第6版):第1章 細胞の一般生理B”(本郷利憲、広重 力、豊田順一 監修)
OKADA Yasunobu
医学書院   2005   
細胞の微細構造と機能.“標準生理学 (第6版):第1章 細胞の一般生理A”(本郷利憲、広重 力、豊田順一 監修)
医学書院   2005   
嚢胞性線維症に関わるCFTR-チャネルおよびレギュレータとしてのABCタンパク質-“ABC蛋白質”(植田和光 編)
学会出版センター   2005   
Essential role of anion channel in induction of apoptotic and necrotic cell death. In, “Ion Channels in the Pulmonary Vasculature” (ed. J. X.-J. Yuan)
Y. Okada, E. Maeno, T. Nabekura & S. Mori (Part:Contributor, pp 527-544)
Taylor & Francis: Boca Raton   2005   
“ギャノング 生理学”(原書21版)
OKADA Yasunobu
丸善   2004   
OKADA Yasunobu
医学書院   2003   
丸善   2002   
序論 イオンチャネル.“新パッチクランプ実験技術法”(岡田泰伸 編)
吉岡書店   2001   
パッチクランプ法総論.“新パッチクランプ実験技術法”(岡田泰伸 編)
吉岡書店   2001   
パッチクランプバイオセンサー法. “新パッチクランプ実験技術法”(岡田泰伸 編)
吉岡書店   2001   
吉岡書店   2001   
Swelling-induced maxi-anion channel in murine C127 cells: ATP-block and ATP-permeation. In, “Electrolyte Transport across Exocrine Epithelia” (eds. A. Dinudum & D.I. Cook)
R.Z. Sabirov, A.K. Dutta & Y. Okada (Part:Contributor, pp 145-146)
University of Sydney Printing House   2001   
The pathway and roles of ATP release from epithelial cells. In, “Electrolyte Transport across Exocrine Epithelia” (eds. A. Dinudum & D.I. Cook)
Y. Okada, R.Z. Sabirov, K. Dezaki, A. Hazama, H.-T. Fan, I. Abdullaev, T. Shimizu, A.K. Dutta, S. Hayashi, Y. Ando-Akatsuka, T. Tsumura & E. Maeno (Part:Contributor, pp 11-13)
University of Sydney Printing House   2001   
細胞とその環境.“標準生理学 (第5版):第1章 細胞の一般生理B”(本郷利憲、広重 力 監修)
OKADA Yasunobu
医学書院   2000   
細胞の容積調節.“シリーズ・ニューバイオフィジックスⅡ” “水と生命-熱力学から生理学へ”.(永山国昭 編)pp140-151
共立出版   2000   
CFTR-dependent and -independent ATP release induced by osmotic swelling. In, “Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels” (eds. Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E.M. Wright)
A. Hazama, Y. Ando-Akatsuka, H.-T. Fan, S. Tanaka & Y. Okada
Elsevier   2000   
In, “Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels” (eds. Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E.M. Wright)
T. Shimizu, S. Morishima & Y. Okada
Elsevier   2000   
Phloretin inhibits a regulatory volume decrease in human epithelial cells. In, “Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels” (eds. Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E.M. Wright)
H.-T. Fan, H. Kida, S. Morishima & Y. Okada
Elsevier   2000   
Cell volume-sensitive Cl channel and ATP release. In, “Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels” (eds. Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E.M. Wright)
Y. Okada, A. Hazama, I. Abdullaev, S. Tanaka, Y. Ando-Akatsuka, T. Shimizu, R. Z. Sabirov, S. Hayashi & H.-T. Fan
Elsevier   2000   
“Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels”
Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E.M. Wright (eds)
Elsevier   2000   
Volume sensor anion channel. In, “Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery”(ed. Y. Okada)
Y. Okada, M. Tominaga, T. Tominaga, A. Hazama, T. Tsumura, S. Morishima, S. Oiki, K. Ueda, T. Miyoshi & A. Miwa
Elsevier   1998   
ATP release from swollen or CFTR-expressing epithelial cells. In, “Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery”(ed. Y. Okada)
A. Hazama, A. Miwa, T. Miyoshi, T. Shimizu & Y. Okada
Elsevier   1998   
Electrophysiological properties of volume-regulated Cl channels in intestinal epithelial cells. In, “Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery” (ed. Y. Okada)
S. Oiki, M. Kubo & Y. Okada
Elsevier   1998   
Water movement during cell volume regulation. In, “Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery” (ed. Y. Okada)
S. Morishima, H. Kida, S. Ueda, T. Chiba & Y. Okada
Elsevier   1998   
Cell Volume RegulatIon : The Molecular Mechanism and Volume Sensing Machinery.
Y. Okada (ed.)
Elsevier, Amsterdam   1998   
Channel and Transporter
Medical View, Tokyo   1997   
吉岡書店   1996   
Patch-clamp experiment methods
Patch-clamp experiment methods   1996   
"Cl Channel: Molecular and Cellular Physiology"
Y. Okada, S. Oiki, S. Yamagishi & K. Hama (eds.)
Center for Academic Publications Japan   1994   
Role of proteases in electrofusion of mammalian cells. In "Electroporation and Electrofusion in Cell Biology" (eds. by E. Neumann, A. E. Sowers & C. A. Jordan)
T. Ohono-Shosaku & Y. Okada
Plenum Publ.   1994   
Ion Channel and Disease.
Molecular Pathology, Bunko-do   1993   
Electrophysiological study of gastric epithelial cell in tissue culture. In, "Gastrointestinal Hormones and Ulcer" (ed. by A. Miyake)
S. Ueda, T. Miyake, H. Uchino, T. Yada & Y. Okada
Biomed. Res. Found.   1983   
Electrophysiological studies on ion transport in intestinal epithelia in vitro. (with Appendix: Liquid junction potential and membrane potential.) In, "Topics in General Physiology and Biophysics" (ed. by The Committee for Publication in Honor of Prof. A
OKADA Yasunobu
Kitami Shobo Publ.   1980   

Research Grants & Projects

Epithelial Transport in Gastrointestinal Tracts
Ionic Mechanism of Apoptosis and Necrosis
Mechanism of Cell Volume Regulation