Hayashi Jun-Ichi

J-GLOBAL         Last updated: Dec 11, 2019 at 09:57
 
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Name
Hayashi Jun-Ichi
E-mail
jih45biol.tsukuba.ac.jp
URL
http://www.biol.tsukuba.ac.jp/~jih-kzt/
Affiliation
University of Tsukuba

Research Areas

 
 

Academic & Professional Experience

 
Apr 2015
 - 
Today
Professors Emeritus, University of Tsukuba
 
Oct 2011
 - 
Mar 2015
Faculty of Live and Environmental Sciences, University of Tsukuba
 
Feb 1985
 - 
Jan 1986
Research Associate, Health Science Center at Dallas, University of Texas
 

Education

 
Apr 1968
 - 
Mar 1972
Faculty of Education, Tokyo Gakugei University
 

Published Papers

 
Haruna Tani, Takayuki Mito, Vidya Velagapudi, Kaori Ishikawa, Moe Umehara, Kazuto Nakada, Anu Suomalainen, Jun-Ichi Hayashi
Sci. Rep.   9 16054   Nov 2019   [Refereed]
Mito-mice∆ and mitochondrial DNA mutator mice as models of human osteoporosis caused not by aging but by hyperparathyroidism.
Takayuki Mito, Haruna Tani, Michiko Suzuki, Kaori Ishikawa, Kazuto Nakada, Jun-Ichi Hayashi
Exp Anim   67 509-517   Oct 2018   [Refereed]
Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal.
Haruna Tani, Sakiko Oonishi, Hiroshi Shitara, Takayuki Mito, Midori Yamaguchi, Hiromichi Yonekawa, Osamu Hashizume, Kaori Ishikawa, Kazuto Nakada, Jun-Ichi Hayashi
Sci Rep   8 425   2018   [Refereed]
Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner.
Chisato Sumi, Akihisa Okamoto, Hiromasa Tanaka, Kenichiro Nishi, Munenori Kusunoki, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Takehiko Adachi, Jun-Ichi Hayashi, Keizo Takenaga, Kiichi Hirota
PLoS ONE   13 e0192796   2018   [Refereed]
Nurun Nahar Borna, et al.
J Hum Genet   62 539-547   2017   [Refereed]
Akinori Shimizu, Haruna Tani, Gaku Takibuchi, Kaori Ishikawa, Ryota Sakurazawa, Takafumi Inoue, Tetsuo Hashimoto, Kazuto Nakada, Keizo Takenaga, and Jun-Ichi Hayashi
Biochem Biophys Res Commun   493 252-257   2017   [Refereed]
Association of predicted pathogenic mutations in mitochondrial ND genes with distant metastasis in NSCLC and colon cancer.
Nobuko Koshikawa, Miho Akimoto, Jun-Ichi Hayashi, Hiroki Nagase, Keizo Takenaga
Sci Rep   7 15535   2017   [Refereed]
Akimoto M, Hayashi J-I, Nakae S, Saito H, Takenaga K
Cell Death Disease   7 e2057   2016   [Refereed]
Jun-Ichi Hayashi, Osamu Hashizume, Kaori Ishikawa, Akinori Shimizu
Current Opinion in Genetics & Development   38 63-67   2016   [Refereed][Invited]
Akinori Shimizu, Shunkei Enoki, Kaori Ishikawa, Takayuki Mito, Kanae Obata, Ruriko Nagashima, Hiromichi Yonekawa, Kazuto Nakada, Jun-Ichi Hayashi
Biochem Biophys Res Commun   459 66-70   2015   [Refereed]
Osamu Hashizume, Sakiko Ohnishi, Takayuki Mito, Akinori Shimizu, Kaori Iashikawa, Kazuto Nakada, Manabu Soda, Hiroyuki Mano, Sumie Togayachi, Hiroyuki Miyoshi, Keisuke Okita, Jun-Ichi Hayashi
Sci Rep   5 10434   2015   [Refereed]
Chisato Hayashi, Gaku Takibuchi, Akinori Shimizu, Takayuki Mito, Kaori Ishikawa, Kazuto Nakada, Jun-Ichi Hayashi
Biochem Biophys Res Commun   463 1021-1027   2015   [Refereed]
Akinori Shimizu, Shunkei Enoki, Kaori Ishikawa, Takayuki Mito, Kanae Obata, Ruriko Nagashima, Hiromichi Yonekawa, Kazuto Nakada, Jun-Ichi Hayashi
Biochem Biophys Res Commun   467 1097-1102   2015   [Refereed]
Osamu Hashizume, Haruka Yamanashi, Makoto M. Taketo, Kazuto Nakada, Jun-Ichi Hayashi
PLoS ONE   10 e0118561   2015   [Refereed]
Takayuki Mito, Hikari Ishizaki, Michiko Suzuki, Hitomi Morishima, Azusa Ota, Kaori Ishikawa, Kazuto Nakada, Akiteru Maeno, Toshihiko Shiroishi, Jun-Ichi Hayashi
Biochem Biophys Res Commun   456 933-937   2015   [Refereed]
Takehiro Takahashi, Masashi Yamamoto, Kazutoshi Amikura, Kozue Kato, Takashi Serizawa, Kanako Serizawa, Daisuke Akazawa, Takumi Aoki, Koji Kawai, Emi Ogasawara, Jun-Ichi Hayashi, Kazuto Nakada and Mie Kainoh
J Pharmacol Exp Ther   352 338-345   2015   [Refereed]
特集:がんと脂質  II. がんと脂質 分子メカニズムへ  5. ミトコンドリア活性酸素とがん
林,純一
The Lipid   25(4) 407-411   Oct 2014
Akinori Shimizu, Takayuki Mito, Chisato Hayashi, Emi Ogasawara, Ryusuke Koba, Issei Negishi, Keizo Takenaga, Kazuto Nakada, Jun-Ichi Hayashi
Proc Natl Acad Sci USA   111(8) 3104-3109   Feb 2014   [Refereed]
We generated transmitochondrial mice (mito-mice) that carry a mutation in the tRNALys gene encoded by mtDNA for use in studies of its pathogenesis and transmission profiles. Because patients with mitochondrial diseases frequently carry mutations i...
New MT-ND6 and NDUFA1 mutations in mitochondrial respiratory chain disorders
Natsumi Uehara, Masato Mori, Yoshimi Tokuzawa, Yosuke Mizuno, Shunsuke Tamaru, Masakazu Kohda, Yohsuke Moriyama, Yutaka Nakachi, Nana Matoba, Tetsuro Sakai, Taro Yamazaki, Hiroko Harashima, Kei Murayama, Keisuke Hattori, Jun-Ichi Hayashi, Takanori Yamagata, Yasunori Fujita, Masafumi Ito, Masashi Tanaka, Ken-ichi Nibu, Akira Ohtake, Yasushi Okazaki
Annals of Clinical and Translational Neurology   1 361-369   2014   [Refereed]
Administration of an antioxidant prevents lymphoma development in transmitochondrial mice overproducing reactive oxygen species.
Haruka Yamanashi, Osamu Hashizume, Hiromichi Yonekawa, Kazuto Nakada, Jun-Ichi Hayashi
Exp Anim   63 459-466   2014   [Refereed]
Shunkei Enoki, Akinori Shimizu, Chisato Hayashi, Hirotake Imanishi, Osamu Hashizume, Kazuyuki Mekada, Hitoshi Suzuki, Tetsuo Hashimoto, Kazuto Nakada, Jun-Ichi Hayashi
Exp Anim   63(1) 21-30   2014   [Refereed]
Gaku Takibuchi, Hirotake Imanishi, Mami Morimoto, Kaori Ishikawa, Kazuto Nakada, Noriko Toyama-Sorimachi, Yoshiaki Kikkawa, Keizo Takenaga, and Jun-Ichi Hayashi
MITOCHONDRION   13(6) 881-887   Nov 2013   [Refereed]
To examine whether polymorphic mtDNA mutations that do not induce significant respiration defects regulate phenotypes of tumor cells, we used mouse transmitochondrial tumor cells (cybrids) with nuclear DNA from C57BL/6 (B6) strain and mtDNA from a...
Mitochondrial DNA with a large-scale deletion causes two distinct mitochondrial disease phenotypes in mice
Shun Katada, Takayuki Mito, Emi Ogasawara, Jun-Ichi Hayashi, Kazuto Nakada
G3: Genes Genomes Genetics   3 1545-1552   Oct 2013   [Refereed]
Hirotake Imanishi, Gaku Takibuchi, Toshihiko Kobayashi, Kaori Ishikawa, Kazuto Nakada, Masayuki Mori, Yoshiaki Kikkawa, Keizo Takenaga, Noriko Toyama-Sorimachi, Jun-Ichi Hayashi
PLOS ONE   8(9) e75981   Sep 2013   [Refereed]
mammalian species, mitochondrial DNA (mtDNA) with pathogenic mutations that induce mitochondrial respiration defects has been proposed to be involved in tumor phenotypes via induction of enhanced glycolysis under normoxic conditions (the Warburg e...
Takayuki, Mito;Yoshiaki, Kikkawa;Akinori, Shimizu;Osamu, Hashizume;Shun, Katada;Hirotake, Imanishi;Azusa, Ota;Yukina, Kato;Kazuto, Nakada;Jun-Ichi, Hayashi
PLOS ONE   8(2) e55789   Jan 2013   [Refereed]
Ishikawa, Kaori;Imanishi, Hirotake;Takenaga, Keizo;Hayashi, Jun-Ichi
J Bioenerg Biomembr   44(6) 639-644   Dec 2012
Kei Watanabe, Kenta Wada, Tomoko Ohashi, Saki Okubo, Kensuke Takekuma, Ryoichi Hashizume, Jun-Ichi Hayashi, Tadao Serikawa, Takashi Kuramoto, Yoshiaki Kikkawa
PLOS ONE   7(11) e50737   Nov 2012   [Refereed]
Osamu Hashizume, Akinori Shimizu, Mutsumi Yokota, Atsuko Sugiyama, Kazuto Nakada, Hiroyuki Miyoshi, Makiko Itami, Miki Ohira, Hiroki Nagase, Keizo Takenaga, and Jun-Ichi Hayashi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   109(26) 10528-10533   Jun 2012   [Refereed]
Junya Yamaguchi, Satoshi Nishiyama, Midori Shimanuki, Tomio Ono, Akitsugu Sato, Kazuto Nakada, Jun-Ichi Hayashi, Hiromichi Yonekawa, Hiroshi Shitara
TRANSGENIC RESEARCH   21(2) 439-447   Apr 2012   [Refereed]
Kazuto Nakada, Jun-Ichi Hayashi
EXPERIMENTAL ANIMALS   60(5) 421-431   Oct 2011   [Refereed]
Mitochondrial genome (mtDNA) mutations and the resultant mitochondrial respiratory abnormalities are associated with a wide variety of disorders, such as mitochondrial diseases, neurodegenerative diseases, diabetes, and cancer, as well as aging. G...
Hirotake Imanishi, Keisuke Hattori, Reiko Wada, Kaori Ishikawa, Sayaka Fukuda, Keizo Takenaga, Kazuto Nakada, Jun-Ichi Hayashi
PLOS ONE   6(8) e23401   Aug 2011   [Refereed]
Hirotake Imanishi, Mutsumi Yokota, Masayuki Mori, Akinori Shimizu, Kazuto Nakada, Jun-Ichi Hayashi
EXPERIMENTAL ANIMALS   60(4) 397-404   Jul 2011   [Refereed]
Mitochondrial diseases
中田, 和人;林, 純一
医学のあゆみ   238(5) 498-504   Jul 2011
Satoshi Nishiyama, Hiroshi Shitara, Kazuto Nakada, Tomio Ono, Akitsugu Sato, Hidenori Suzuki, Tetsuya Ogawa, Haruhiko Masaki, Jun-Ichi Hayashi, Hiromichi Yonekawa
Biochem Biophys Res Commun   401(1) 26-31   Oct 2010   [Refereed]
Kaori Ishikawa, Noriko Toyama-Sorimachi, Kazuto Nakada, Mami Morimoto, Hirotake Imanishi, Mariko Yoshizaki, Shigemi Sasawatari, Mamoru Niikura, Keizo Takenaga, Hiromichi Yonekawa, and Jun-Ichi Hayashi
J Exp Med   207(11) 2297-2305   Oct 2010   [Refereed]
Mutsumi Yokota, Hiroshi Shitara, Osamu Hashizume, Kaori Ishikawa, Kazuto Nakada, Rie Ishii, Choji Taya, Keizo Takenaga, Hiromichi Yonekawa, and Jun-Ichi Hayashi
FEBS LETTERS   584(18) 3943-3948   Sep 2010   [Refereed]
Shin-Ichi Inoue, Shinichi Noda, Koutarou Kashima, Kazuto Nakada, Jun-Ichi Hayashi, Hiroyuki Miyoshi
FEBS LETTERS   584(15) 3402-3409   Aug 2010
Emi Ogasawara, Kazuto Nakada, and Jun-Ichi Hayashi
HUMAN MOLECULAR GENETICS   19(16) 3179-3189   Aug 2010   [Refereed]
Hiroshi Shitara, Midori Shimanuki, Jun-Ichi Hayashi, and Hiromichi Yonekawa
EXPERIMENTAL ANIMALS   59(1) 99-103   Jan 2010   [Refereed]
The most common approach to analyzing the static morphology of mitochondria involves staining by antibodies or fluorescent dyes specific for mitochondrial components. In this study, we present a new approach using transgenic (Tg) mice, mtGFP-Tg mi...
Pathogenesis by failures of mitochondrial central dogma
中田, 和人;石川, 香;林, 純一
Cell technology   29(5) 466-473   Jan 2010
Kaori Ishikawa and Jun-Ichi Hayashi
Ann NY Acad Sci   1201 40-43   2010   [Refereed][Invited]
Liqin Cao, Hiroshi Shitara, Michihiko Sugimoto, Jun-Ichi Hayashi, Kuniya Abe, and Hiromichi Yonekawa
PLOS Genet   5(12) 0-0   Dec 2009   [Refereed]
Nobuko Koshikawa, Jun-Ichi Hayashi, Akira Nakagawara, and Keizo Takenaga
JOURNAL OF BIOLOGICAL CHEMISTRY   284(48) 33185-33194   Nov 2009   [Refereed]
Kazuto Nakada, Akitsugu Sato, Jun-Ichi Hayashi
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY   41(10:::Sp. Iss. SI) 1907-1913   Oct 2009   [Refereed][Invited]
Akitsugu Sato, Kazuto Nakada, Jun-Ichi Hayashi
BIOFACTORS   35(2) 130-137   Mar 2009   [Refereed]
Mitochondria theory of tumor metastasis: ROS-generating mtDNA mutations reversibly regulate tumor cell metastasis
石川, 香;林, 純一
Protein, nucleic acid and enzyme   54(1) 40-48   Jan 2009
Normal mitochondrial respiratory function is essential for spatial remote memory in mice.
Daisuke Tanaka, Kazuto Nakada, Keizo Takao, Emi Ogasawara, Atsuko Kasahara, Akitsugu Sato, Hiromichi Yonekawa, Tsuyoshi Miyakawa and Jun-Ichi Hayashi
Molecular Brain   1 21   Jan 2009   [Refereed]
Kaori Ishikawa, Jun-Ichi Hayashi
Cell Adhesion and Migration   3 11-13   2009   [Refereed][Invited]
Mitochondrial function, Part B: Mitochondrial Protein Kinases, Protein Phosphates, and Mitochondrial Diseases
Kaori Ishikawa and Jun-Ichi Hayashi
Methods in Enzymology   457 335-346   2009   [Refereed][Invited]
NAKADA,Kazuto;SATO,Akitsugu;HAYASHI,Jun-Ichi
Clinical neurology.   48(11) 1013-1015   Nov 2008   [Refereed]
Kaori Ishikawa, Osamu Hashizume, Nobuko Koshikawa, Sayaka Fukuda, Kazuto Nakada, Keizo Takenaga, and Jun-Ichi Hayashi
FEBS LETTERS   582(23-24) 3525-3530   Oct 2008   [Refereed]
Kaori Ishikawa, Nobuko Koshikawa, Keizo Takenaga, Kazuto Nakada, Jun-Ichi Hayashi
MITOCHONDRION   8(4) 339-344   Sep 2008   [Refereed]
Shoko Tamai, Hiroshi Iida, Sadaki Yokota, Tomoko Sayano, Shoko Kiguchiya, Naotada Ishihara, Jun-Ichi Hayashi, Katsuyoshi Mihara, and Toshihiko Oka
JOURNAL OF CELL SCIENCE   121(15) 2588-2600   Aug 2008   [Refereed]
Nakada, Kazuto;Sato, Akitsugu;Hayashi, Jun-Ichi
Proceedings of the Japan Academy, Series B   84(5) 155-165   May 2008   [Refereed]
Kaori Ishikawa, Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Aya Yamaguchi, Hirotake Imanishi, Kazuto Nakada, Yoshio Honma, and Jun-Ichi Hayashi
Science   320(5876) 661-664   May 2008   [Refereed]
Generation of model mice expressing mitochondrial-genome diseases
HAYASHI Jun-Ichi
DNA多型 = DNA polymorphism   16(0) 1-6   May 2008   [Refereed]
フリーラジカルとエイジング--ミトコンドリア間相互作用から老化ミトコンドリア原因説を再考する (特集 エイジングの科学)
中田, 和人;林, 純一
Journal of health,physical education and recreation   58(4) 242-246   Apr 2008
Akitsugu Sato, Kazuto Nakada, Hiroshi Shitara, Atsuko Kasahara, Hiromichi Yonekawa, Jun-Ichi Hayashi
GENETICS   177(4) 2031-2037   Dec 2007   [Refereed]
Sin-Ichi Inoue, Mutsumi Yokota, Kazuto Nakada, Hiroyuki Miyoshi, and Jun-Ichi Hayashi
FEBS LETTERS   581(9) 1910-1916   May 2007   [Refereed]
Izuru Yonemura, Kazuto Nakada, Akitsugu Sato, Jun-Ichi Hayashi, Kyoko Fujita, Shinya Kaneko, and Mitsuhiro Itaya
GENE   391(1-2) 171-177   Apr 2007   [Refereed]
Liqin Cao, Hiroshi Shitara, Takuro Horii, Yasumitsu Nagao, Hiroshi Imai, Kuniya Abe, Takahiko Hara, Jun-Ichi Hayashi, Hiromichi Yonekawa
Nature Genet   39(3) 386-390   Mar 2007   [Refereed]
Chen, Jing;Hattori, Yukiko;Nakajima, Kazuo;Eizawa, Takayuki;Ehara, Takashi;Koyama, Masamichi;Hirai, Tetsuya;Fukuda, Youji;Kinoshita, Moritoshi;Sugiyama, Atsushi;Hayashi, Jun-Ichi;Onaya, Toshimasa;Kobayashi, Tetsuro;Tawata, Masato
Diabetes Res Clinical Practice   74(2) 148-153   Nov 2006   [Refereed]
Kazuto Nakada, Akitsugu Sato, Kayo Yoshida, Takashi Morita, Hiromitsu Tanaka, Shin-Ichi Inoue, Hiromichi Yonekawa, and Jun-Ichi Hayashi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   103(41) 15148-15153   Oct 2006   [Refereed]
Matthias Schauen, Dimitry Spitkovsky, Jens Schubert, Jurgen H. Fischer, Jun-Ichi Hayashi, and Rudolf J. Wiesner
JOURNAL OF CELLULAR PHYSIOLOGY   209(1) 103-112   Oct 2006   [Refereed]
Atsuko Kasahara, Kaori Ishikawa, Makiko Yamaoka, Masahito Ito, Naoki Watanabe, Miho Akimoto, Akitsugu Sato, Kazuto Nakada, Hitoshi Endo, Yoko Suda, Shinichi Aizawa, and Jun-Ichi Hayashi
Hum Mol Genet   15(6) 871-881   Mar 2006   [Refereed]
Maiko Natsume, Yositaka Iwamuro, Masahiro Tanaka, Chie Itoi, Haruka Murakami, and Jun- Ichi Hayashi
International Journal of Sport and Health Science   4(2) 628-632   Jan 2006   [Refereed]
A mouse fibroblast cell line, B82, was treated with H2O2 for examination of the damage to mtDNA and to respiratory function. The results showed that the copy numbers of intact mtDNA molecules reduced rapidly during 15 minutes H2O2 treatment, while...
Haruka Murakami, Ryuichi Ajisaka, Jun-Ichi Hayashi, and Shinya Kuno
International Journal of Sport and Health Science   4(2) 472-479   Jan 2006   [Refereed]
The purpose of the present study was to investigate the relationship between the polymorphisms of ATP synthase 8, 6 gene and the individual difference of the endurance capacity or its trainability. Sixty-nine sedentary adult males participated in ...
Special Review 哺乳類ミトコンドリアDNAにおける組換え
佐藤, 晃嗣;中田, 和人;林, 純一
Cell technology.   25(1) 54-59   Jan 2006
Shin-Ichi Inoue, Kaori Ishikawa, Kazuto Nakada, Akitsugu Sato, Hiroyuki Miyoshi, Jun-Ichi Hayashi
Hum Mol Genet   15 1801-1807   Jan 2006   [Refereed]
Akitsugu Sato, Kazuto Nakada, Jun-Ichi Hayashi
Biochim Biophys Acta   1763 473-481   2006   [Refereed][Invited]
Akitsugu Sato, Tomohiro Kono, Kazuto Nakada, Kaori Ishikawa, Shin-Ichi Inoue, Hiromichi Yonekawa, and Jun-Ichi Hayashi
Proc Natl Acad Sci USA   102(46) 16765-16770   Nov 2005   [Refereed]
生きているGFPミトコンドリアの長期観察 (二層膜オルガネラの遺伝学) -- (オルガネラテクノロジー 動物ミトコンドリアのテクノロジー)
設楽, 浩志;林, 純一;米川, 博通
Protein, nucleic acid and enzyme   50(14) 1909-1911,1712   Nov 2005
ミトコンドリア移植による病原性ミトコンドリアDNAの診断 (二層膜オルガネラの遺伝学) -- (オルガネラテクノロジー 動物ミトコンドリアのテクノロジー)
石川, 香;林, 純一
Protein, nucleic acid and enzyme   50(14) 1904-1906   Nov 2005
ミトコンドリアゲノムの相補作用 (二層膜オルガネラの遺伝学) -- (オルガネラダイナミクス 動物オルガネラダイナミクス)
佐藤, 晃嗣;林, 純一
Protein, nucleic acid and enzyme   50(14) 1863-1867,1712   Nov 2005
ミトコンドリア遺伝子病モデルマウス (二層膜オルガネラの遺伝学) -- (哺乳類のミトコンドリア 哺乳類ミトコンドリアゲノムの変異と疾患)
中田, 和人;林, 純一
Protein, nucleic acid and enzyme   50(14) 1774-1777   Nov 2005
ミトコンドリアDNAの母性遺伝と組換え (二層膜オルガネラの遺伝学) -- (哺乳類のミトコンドリア 哺乳類ミトコンドリアゲノムの遺伝と進化)
佐藤, 晃嗣;設楽, 浩志;林, 純一
Protein, nucleic acid and enzyme   50(14) 1744-1748   Nov 2005
ミトマウスを用いた糖尿病発症における変異型ミトコンドリアゲノムの病原性の検証 (特集 細胞の生と死を司るミトコンドリア)
中田, 和人;佐藤, 晃嗣;林, 純一
Cell technology.   24(8) 820-824   Aug 2005
Kaori Ishikawa, Atsuko Kasahara, Naoki Watanabe, Kazuto Nakada, Akitsugu Sato, Yoko Suda, Shinichi Aizawa, and Jun-Ichi Hayashi
Biochem Biophys Res Commun   333(2) 590-595   Jul 2005   [Refereed]
Velocity of mitochondria in a fibroblast cell
Shitara, Hiroshi;Sato, Akitsuga;Hayashi, Jun-ichi;Yonekawa, Hiromichi
CELL STRUCTURE AND FUNCTION   30(Suppl. S) 15-15   Jun 2005   [Refereed]
Kawamura, S;Takai, D;Watanabe, K;Hayashi, J;Hayakawa, K;Akashi, M
JOURNAL OF HEALTH SCIENCE   51(3) 385-393   Jun 2005   [Refereed]
Akitsugu Sato, Kazuto Nakada, Miho Akimoto, Kaori Ishikawa, Tomoko Ono, Hiroshi Shitara, Hiromichi Yonekawa, and Jun-Ichi Hayashi
Proc Natl Acad Sci USA   102(17) 6057-6062   Apr 2005   [Refereed]
Miho Akimoto, Mamoru Niikura, Masami Ichikawa, Hiromichi Yonekawa, Kazuto Nakada, Yoshio Honma, and Jun-Ichi Hayashi
Biochem Biophys Res Commun   327(4) 1028-1035   Feb 2005   [Refereed]
Kazuto Nakada, Akitsugu Sato, Hideyuki Sone, Atsuko Kasahara, Katsuhisa Ikeda, Yasuo Kagawa, Hiromichi Yonekawa, and Jun-Ichi Hayashi
Biochem Biophys Res Commun   323(1) 175-184   Oct 2004   [Refereed]
Akitsugu Sato, Kazuto Nakada, Hiroshi Shitara, Hiromichi Yonekawa, and Jun-Ichi Hayashi
GENETICS   167(4) 1855-1861   Aug 2004   [Refereed]
Shitara,H;Sato,A;Hayashi,J;Mizushima,N;Yonekawa,H;Taya,C
Transgenic Res   13(2) 191-194   Apr 2004   [Refereed]
ミトコンドリア病の研究に有効なモデル細胞とモデルマウス (特集1 ミトコンドリア病--病因・病態の分子メカニズム)
中田, 和人;林, 純一
Molecular medicine   41(3) 306-312   Mar 2004
Chu-Shih Chen, Rumiko Matsuoka, Shoichi Arai, Yukihiko Momiyama, Haruka Murakami, Shin-ya Kuno, Kaori Ishikawa, Kazuto Nakada, Masato Tawata, and Jun-Ichi Hayashi
J Biochem   135(2) 237-243   Feb 2004   [Refereed]
Tomoko Ono, Yoshiko Kasahara, Kazuto Nakada, and Jun-Ichi Hayashi
Biochem Biophys Res Commun   314(4) 1107-1112   Feb 2004   [Refereed]
ミトコンドリア連携説
中田, 和人;小野, 朋子;林, 純一
Gene & medicine   7(2) 273-276   Jun 2003
Mayumi Okamoto, Takashi Ohsato, Kazuto Nakada, Kotoyo Isobe, Johannes N. Spelbrink, Jun-Ichi Hayashi, Naotaka Hamasaki, Dongchon Kang
Current Genet   43 364-370   Jan 2003   [Refereed]
Noriko Enomoto, Nobuko Koshikawa, Max Gassmann, Jun-Ichi Hayashi, and Keizo Takenaga
Biochem Biophys Res Commun   297 346-352   Jan 2002   [Refereed]
Kimiko Inoue, Atsuo Ogura, and Jun-Ichi Hayashi
Methods   26 358-363   Jan 2002   [Refereed]
un-Ichi Hayashi, Kazuto Nakada, and Tomoko Ono
Nature Genetics   30 361   Jan 2002   [Refereed]
Kazuto Nakada, Tomoko Ono, Kotoyo Isobe, Kimiko Inoue, and Jun-Ichi Hayashi
Mitochondrion   2(1-2) 59-70   Jan 2002   [Refereed]
Yoshinori Takahashi, Koichiro Kako, Shin-ichi Kashiwabara, Akio Takehara,Yoshiko Inada, Hidenori Arai, Kazuto Nakada, Hiroko Kodama, Jun-Ichi Hayashi, Tadashi Baba, and Eisuke Munekata
Mol Cell Biol   22 7614-7621   Jan 2002   [Refereed]
Special Review ミトコンドリア遺伝子疾患を阻止するミトコンドリア間相互作用
中田, 和人;小野, 朋子;林, 純一
Cell technology.   20(11) 1552-1565   Nov 2001
Haruka Murakami, Rika Soma, Jun-ichi Hayashi, Shigeru Katsuta, Mitsuo Matsuda, Ryuichi Ajisaka, Morihiko Okada, and Shinya Kuno
Jpn J Physiol   51(5) 563-568   Oct 2001   [Refereed]
Rika Soma, Haruka Murakami, Jun-Ichi Hayashi, Sayaka Ito, Jun Nagai, Masaaki Sugita, Shin-ya Kuno, and Morihiko Okada
Jpn J Physiol   51(4) 475-480   Aug 2001   [Refereed]
Kazuto Nakada, Kimiko Inoue, Chu-Shih Chen, Ikuya Nonaka, Yu-ichi Goto, Atsuo Ogura, and Jun-Ichi Hayashi
Biochem Biophys Res Commun   288 901-907   Jan 2001   [Refereed]
Kazuto Nakada, Kimiko Inoue, Tomoko Ono, Kotoyo Isobe, Atsuo Ogura, Yu-ichi Goto, Ikuya Nonaka, and Jun-Ichi Hayashi
Nature Med.   7 934-939   Jan 2001   [Refereed]

Books etc

 
ニュートン別冊 細胞のしくみ 2細胞内のエネルギー生産工場 PART 1 最重要の細胞内器官「ミトコンドリア」
(編集協力者)近藤祥司;林, 純一;水島, 昇;吉田賢右
ニュートン・ニュートンプレス   2013   
ニュートン12月号 ニュートンスペシャル: ミトコンドリア(今、解き明かされる最重要の細胞内器官)
(編集協力者)近藤祥司;林, 純一;水島, 昇;吉田賢右
ニュートン・ニュートンプレス   Dec 2012   
Mitochondria in Relation to Cancer Metastasis: Regulation of metastasis; mitochondrial DNA mutations have appeared on stage
Kaori Ishikawa; Hirotake Imanishi; Keizo Takenaga; Jun-Ichi Hayashi; + 林 純一; (Part:Supervisor)
J Bioenerg Biomembr
   Jan 2012   
特集:ミトコンドリア病―up to date 総論と基礎知識:ミトコンドリア病のモデルマウス
中田和人;林, 純一 (Part:Supervisor)
Clinical Neuroscience   2012   
実験医学増刊:がんと代謝 第1章エネルギー代謝 6ミトコンドリアにおける活性酸素種生成とがんの代謝
竹永, 啓三;林, 純一 (Part:Supervisor)
実験医学増刊30巻、15号 編集:曽我朋義、江角浩安   2012   
卵子学  第VII章 卵子成熟 31 卵子ミトコンドリアDNA
設楽浩志;佐藤晃嗣;林, 純一 (Part:Contributor)
京都大学学術出版会   Sep 2011   
HOT PRESS:自然免疫系によるミトコンドリアDNA多型突然変異の認識と選択的排除
今西泰赳;石川, 香;反町典子;林, 純一 (Part:Supervisor)
細胞工学・学研メディカル秀潤社   Apr 2011   
第I部 生物機能モデルの作製と利用 第2章 恒常性維持 第4節 オルガネラの機能とその異常 第1項 ミトコンドリア
中田和人;林, 純一 (Part:Contributor)
seriesモデル動物利用マニュアル:生物機能モデルと新しいリソース・リサーチツール・株式会社 エル・アイ・シー   Feb 2011   
特集:その時ミトコンドリアは動いた(独自の品質管理システムから疾患に迫る) ミトコンドリアセントラルドグマの破綻病理
中田和人;石川, 香;林, 純一 (Part:Supervisor)
細胞工学・学研メディカル秀潤社   May 2010   
特集:ここまでわかったミトコンドリア研究の新展開: ミトコンドリア医学のひろがりと発展(座談会)
太田成男;林, 純一;北, 潔;田中雅嗣 (Part:Supervisor)
医学のあゆみ(医歯薬出版)   Feb 2010   

Conference Activities & Talks

 
Determination of entire physiological roles of mammalian mtDNA via its various disruption [Invited]
林,純一
第24回つくば賞授賞式・受賞記念講演会   26 Nov 2013   
ミトコンドリアミステリー2 [Invited]
林,純一
生物学類サイエンスカフェ:第74回バイオeカフェ   15 Oct 2013   
A novel function of mtDNA: its involvement in metastasis [Invited]
Ishikawa, Kaori;Hayashi, Jun-Ichi
6th Conference of the Asian-Society-for-Mitochondrial-Research-and-Medicine   31 Oct 2009   

Research Grants & Projects

 
Influence of mitochondrial DNA mutations on human health
Role of mtDNA mutations on pathogenesis of mitochondirial diseases, diabetes, and aging
Inheritance and interaction of mammalian mitochondrial DNAs

Patents

 
2000-9194 : 変異型ミトコンドリアDNAの生殖細胞への導入方法
林, 純一