小俣義明 (Yoshiaki Omata) - マイポータル - researchmap

基本情報

所属: 旧所属久留米大学医学部医学科

学位: 理学修士(東京理科大学)
薬学博士(東京理科大学)

J-GLOBAL ID: 200901075557565033
researchmap会員ID: 1000180638

研究キーワード

1

生物物理化学

研究分野

3

経歴

6

1991年 - 1994年

米国National Institutes of Health, Visiting
1988年 - 1991年

米国National Institutes of Health, Visiting
1987年 - 1988年

National Institute of Health, Research
Associate
Fellow
Resident

学歴

3

MISC

38

Purification and characterization of a soluble form of rat liver NADPH-cytochrome P-450 reductase highly expressed in Escherichia coli

S Hayashi, Y Omata, H Sakamoto, T Hara, M Noguchi

PROTEIN EXPRESSION AND PURIFICATION 29(1) 1-7 2003年5月
The reactivity of α-hydroxyhaem and verdohaem bound to haem oxygenase-1 to dioxygen and sodium dithionite.

269(21) 5231-5239 2002年11月
Crystal structure of rat heme oxygenase-1 in complex with heme bound to azide: Implication for regiospecific hydroxylation of heme at the α-meso carbon.

277(47) 45086-45090 2002年11月
The reactivity of alpha-hydroxyhaem and verdohaem bound to haem oxygenase-1 to dioxygen and sodium dithionite

H Sakamoto, Y Omata, S Hayashi, S Harada, G Palmer, M Noguchi

EUROPEAN JOURNAL OF BIOCHEMISTRY 269(21) 5231-5239 2002年11月
Crystal structure of rat apo-heme oxygenase-1 (HO-1): Mechanism of heme binding in HO-1 inferred from structural comparison of the apo and heme complex forms

M Sugishima, H Sakamoto, Y Kakuta, Y Omata, S Hayashi, M Noguchi, K Fukuyama

BIOCHEMISTRY 41(23) 7293-7300 2002年6月
Crystal Structure of Rat Apo-heme Oxygenase-1 (HO-1): Mechanism of Heme Binding in HO-1 Inferred From Structual Comparison of the Apo and Heme Complex Forms （共著）

Biochemistry 41(23), 7293-7300 2002年
Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme Bound to Azide: Implication for Regiospecific Hydroxylation of Heme at the α-meso Carbon（共著）

J. Biol. Chem 277(47), 45086-45090 2002年
Crystal structure of a rat heme oxygenase-1 in complex with heme.

2000年
The cytochrome P450 2B1 recognition domain for NADPH-cytochrome P450 reductase.

2000年
Heme oxyganase 1 (HSP-32) is induced in myelin-phagocytosing Schwann cells of injured rat sciatic nerves.

2000年
Separation and identification of the regioisomers of verdoheme by reversed-phase ion-pair high-performance liquid chromatography, and characterization of their complexes with heme oxygenase."

2000年
Crystal structure of a rat heme oxygenase-1 in complex with heme(共著)

FEBS Lett. 471(1) 61-66 2000年
Synthetic peptide mimics of a predicted topographical interaction surface : the cytochrome P450 2B1 recognition domain for NADPH-cytochrome P450 reductase(共著)

J. Protein Chem. 19(1) 23-32 2000年
Heme oxyganase 1(HSP-32)is induced in myelin-phagocytosing Schwann cells of injured rat sciatic nerves(共著)

Eur. J. Neurosci. 12(11) 4147-4152 2000年
Separation and identification of the regioisomers of verdoheme by reversed-phase ion-pair High-performance Liquid chromatography, and charcterization of their comlexes with heme oxygenase(共著)

J. Inorg. Biochem. 82 113-121 2000年
Ferric α-hydroxyheme bound to heme oxygenase can be converted to verdoheme by dioxygen in the absence of added reducing equivalents.

1999年
Ferric α-hydroxyheme bound to heme oxygenase can be converted to verdoheme by dioxygen in the absence of added reducing equivalents(共著)

J. Biol. Chem. 274(26) 18196-18200 1999年
A spectroscopic study on the intermediates of heme degradation by heme oxygenase.

1998年
Crystallization and preliminary X-ray diffraction studies on the water soluble form of rat heme oxygenase-1 in complex with heme.

1998年
Crystallization and preliminary X-ray diffraction studies on the water soluble form of rat heme oxygenase-1 in complex with heme(共著)

Acta Cryst. D54(1017-1019) 1998年

もっとみる

書籍等出版物

2

A spectroscopic study on the intermediates of heme degradation by heme oxygenase(共著)

"Oxygen Homeostasis and its Dynamics" Springer Verlag, 1997年
Subcellular distribution and macromolecular binding of aflatoxin(共著)

"Microbial Toxins in Foods and Feeds, " Plenum Press 1990年

共同研究・競争的資金等の研究課題

3