喜多村直実 (KITAMURA NAOMI) - マイポータル - researchmap

基本情報

所属: 東京工業大学名誉教授

学位: 薬学博士(東京大学)

J-GLOBAL ID: 200901062650152062
researchmap会員ID: 1000181812

研究分野

2

経歴

8

1995年

-:
1995年

-:東京工業大学教授
1987年

-:
1987年

-:関西医科大学教授
1982年

-:
1982年

-:京都大学助教授
1976年

-:
1976年

-:東京大学助手

学歴

3

受賞

1

1986年

日本生化学会奨励賞

MISC

88

Id1 Is Down-Regulated by Hepatocyte Growth Factor via ERK-Dependent and ERK-Independent Signaling Pathways, Leading to Increased Expression of p16(INK4a) in Hepatoma Cells

Kazutaka Ushio, Tomio Hashimoto, Naomi Kitamura, Toshiaki Tanaka

MOLECULAR CANCER RESEARCH 7(7) 1179-1188 2009年7月
Up-Regulation of p21(CIP1) Expression Mediated by ERK-Dependent and -independent Pathways Contributes to Hepatocyte Growth Factor-induced Inhibition of HepG2 Hepatoma Cell Proliferation

Erika Shirako, Naoki Hirayama, Yu-ichi Tsukada, Toshiaki Tanaka, Naomi Kitamura

JOURNAL OF CELLULAR BIOCHEMISTRY 104(1) 176-188 2008年5月
Up-regulation of p21CIP1 expression mediated by ERK-dependent and 窶妬ndependent pathways contributes to hepatocyte growth factor-induced inhibition of HepG2 hapatoma cell proliferation

Erika Shirako, Naoki Hirayama, Yu-ich Tsukada, Toshiaki Tanaka, Naomi Kitamura

J.Cell.Biochem. 104(1) 176-188 2008年5月
Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

Akiko Mukai, Emi Mizuno, Kaoru Kobayashi, Masaki Matsumoto, Keiichi I. Nakayama, Naomi Kitamura, Masayuki Komada

JOURNAL OF CELL SCIENCE 121(8) 1325-1333 2008年4月
Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation

Asuka Kondo, Naoki Hirayama, Yasuko Sugito, Michihiro Shono, Toshiaki Tanaka, Naomi Kitamura

JOURNAL OF BIOLOGICAL CHEMISTRY 283(3) 1428-1436 2008年1月
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase

Emi Mizuno, Naomi Kitamura, Masayuki Komada

EXPERIMENTAL CELL RESEARCH 313(16) 3624-3634 2007年10月
The Ca2(+)-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A

Akinori Yamasaki, Katsuko Tani, Akitsugu Yamamoto, Naomi Kitamura, Masayuki Komada

MOLECULAR BIOLOGY OF THE CELL 17(11) 4876-4887 2006年11月
A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes

Emi Mizuno, Kaoru Kobayashi, Akitsugu Yamamoto, Naomi Kitamura, Masayuki Komada

TRAFFIC 7(8) 1017-1031 2006年8月
Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes

M Nakamura, N Tanaka, N Kitamura, M Komada

GENES TO CELLS 11(6) 593-606 2006年6月
Enhanced JNK activation by NESK without kinase activity upon caspase-mediated cleavage during apoptosis

H Kakinuma, H Inomata, N Kitamura

CELLULAR SIGNALLING 17(11) 1439-1448 2005年11月
Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes

E Mizuno, T Iura, A Mukai, T Yoshimori, N Kitamura, M Komada

MOLECULAR BIOLOGY OF THE CELL 16(11) 5163-5174 2005年11月
Hepatocyte growth factor induces redistribution of p21(CIP1) and p27(KIP1) through ERK-dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G(1) in HepG2 hepatoma cells

JH Han, Y Tsukada, E Hara, N Kitamura, T Tanaka

JOURNAL OF BIOLOGICAL CHEMISTRY 280(36) 31548-31556 2005年9月
The Hrs/STAM complex in the downregulation of receptor tyrosine kinases

M. Komada, N. Kitamura

J. Biochem. 137(1) 1-8 2005年
Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantonic placenta

H. Tanaka, K, Nagaike, N. Takeda, H. Itoh, K. Kohama, T. Fukushima, S. Miyata, S. Uchiyama, S. Uchinokura …

Mol. Cell. Biol. 25(13) 5687-5698 2005年
Hepatocyte growth factor induces redistribution of p21CIP1 and p27KIP1 through ERK-dependent p16INK4a up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells.

J.Han, Y.Tsukada, E.Hara, N.Kitamura, T.Tanaka

J.Biol.Chem. 280(36) 31548-31556 2005年
The Hrs/STAM complex in the downregulation of receptor tyrosine kinases

M Komada, N Kitamura

JOURNAL OF BIOCHEMISTRY 137(1) 1-8 2005年1月
Enhanced JNK activation by NESK without kinase activity upon caspase-mediated cleavage during apoptosis

H. Kakinuma, H. Inomata N Kitamura

Cell. Signal. 17 1439-1448 2005年
Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantonic placenta

H. Tanaka, K, Nagaike, N. Takeda, H. Itoh, K. Kohama, T. Fukushima, S. Miyata, S. Uchiyama, S. Uchinokura …

Mol. Cell. Biol. 25(13) 5687-5698 2005年
Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2

Y Tsukada, T Tanaka, K Miyazawa, N Kitamura

JOURNAL OF BIOCHEMISTRY 136(5) 701-709 2004年11月
Activation of c-Met (hepatocyte growth factor receptor) in human gastric cancer tissue

T Inoue, H Kataoka, K Goto, K Nagaike, K Igami, D Naka, N Kitamura, K Miyazawa

CANCER SCIENCE 95(10) 803-808 2004年10月

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2