論文

2008年2月

Brain maturation-related spike localization in Panayiotopoulos syndrome: Magnetoencephalographic study

PEDIATRIC NEUROLOGY
  • Naka Saito
  • ,
  • Osamu Kanazawa
  • ,
  • Jun Tohyama
  • ,
  • Noriyuki Akasaka
  • ,
  • Takanori Kamimura
  • ,
  • Shin-ichi Toyabe
  • ,
  • Makoto Uchiyama

38
2
開始ページ
104
終了ページ
110
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.pediatrneurol.2007.08.020
出版者・発行元
ELSEVIER SCIENCE INC

Focal spike activities in Panayiotopoulos syndrome involve all brain regions in electroencephalography, and commonly reveal multiple foci, often through occipital predominance. To investigate correlations between developmental brain maturation and spike origin in Panayiotopoulos syndrome, we evaluated age-related or duration-related magnetoencephalographic spike localization in 25 patients with Panayiotopoulos syndrome. Regarding age at examination, patients with frontal spikes were significantly older than patients with spikes on rolandic, parieto-occipital, or calcarine sulci. Occipital spikes were classified into two subgroups, located at the calcarine sulcus and parieto-occipital sulcus. Both calcarine and parieto-occipital localizations were seen in patients around the same age. Follow-up magnetoencephalography was performed on three patients, and demonstrated shifting localization or disappearance of magnetoencephalographic spikes. These results suggest that the location of spike discharges is not directly related to seizure symptoms, but instead indicates maturation-related cortical hyperexcitability in patients with Panayiotopoulos syndrome. (c) 2008 by Elsevier Inc. All rights reserved.

リンク情報
DOI
https://doi.org/10.1016/j.pediatrneurol.2007.08.020
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000252792800005&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.pediatrneurol.2007.08.020
  • ISSN : 0887-8994
  • Web of Science ID : WOS:000252792800005

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