北山仁志 (Hitoshi Kitayama) - マイポータル

基本情報

所属: 京都大学大学院医学研究科医学専攻助教授

学位: 理学博士

J-GLOBAL ID: 200901011336170788
researchmap会員ID: 1000181998

研究分野

学歴

受賞

1995年

日本癌学会奨励賞

論文

The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs

Mako Yamamoto, Tomoko Matsuzaki, Rei Takahashi, Eijiro Adachi, Yasuhiro Maeda, Sachiyo Yamaguchi, Hitoshi Kitayama, Michiko Echizenya, Yoko Morioka, David B. Alexander …

BIOLOGY OPEN 1(5) 458-466 2012年5月査読有り
A novel screen using the Reck tumor suppressor gene promoter detects both conventional and metastasis-suppressing anticancer drugs

Ryuya Murai, Yoko Yoshida, Teruyuki Muraguchi, Emi Nishimoto, Yoko Morioka, Hitoshi Kitayama, Shinae Kondoh, Yoshinori Kawazoe, Masahiro Hiraoka, Motonari Uesugi …

ONCOTARGET 1(4) 252-264 2010年8月査読有り
Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice

Ediriweera P. S. Chandana, Yasuhiro Maeda, Akihiko Ueda, Hiroshi Kiyonari, Naoko Oshima, Mako Yamamoto, Shunya Kondo, Junseo Oh, Rei Takahashi, Yoko Yoshida …

BMC DEVELOPMENTAL BIOLOGY 10 2010年8月査読有り
What we learn from transformation suppressor genes: lessons from RECK

Makoto Noda, Chiaki Takahashi, Tomoko Matsuzaki, Hitoshi Kitayama

FUTURE ONCOLOGY 6(7) 1105-1116 2010年7月査読有り
Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs

F. Loayza-Puch, Y. Yoshida, T. Matsuzaki, C. Takahashi, H. Kitayama, M. Noda

ONCOGENE 29(18) 2638-2648 2010年5月査読有り
Transplantation of cultured choroid plexus epithelial cells via cerebrospinal fluid shows prominent neuroprotective effects against acute ischemic brain injury in the rat

Naoya Matsumoto, Akihiko Taguchi, Hitoshi Kitayama, Yumi Watanabe, Masayoshi Ohta, Tomoyuki Yoshihara, Yutaka Itokazu, Mari Dezawa, Yoshihisa Suzuki, Hisashi Sugimoto …

NEUROSCIENCE LETTERS 469(3) 283-288 2010年1月査読有り
The membrane-anchored metalloproteinase regulator RECK stabilizes focal adhesions and anterior-posterior polarity in fibroblasts

Y. Morioka, J. Monypenny, T. Matsuzaki, S. Shi, D. B. Alexander, H. Kitayama, M. Noda

ONCOGENE 28(11) 1454-1464 2009年3月査読有り
RECK Forms Cowbell-shaped Dimers and Inhibits Matrix Metalloproteinase-catalyzed Cleavage of Fibronectin

Akira Omura, Tomoko Matsuzaki, Kazuhiro Mio, Toshihiko Ogura, Mako Yamamoto, Akiko Fujita, Katsuya Okawa, Hitoshi Kitayama, Chiaki Takahashi, Chikara Sato …

JOURNAL OF BIOLOGICAL CHEMISTRY 284(6) 3461-3469 2009年2月査読有り
Identification of Rgl3 as a potential binding partner for Rap-family small G-proteins and profilin II

Jiegou Xu, Shuliang Shi, Naoya Matsumoto, Makoto Noda, Hitoshi Kitayama

CELLULAR SIGNALLING 19(7) 1575-1582 2007年7月査読有り
Dual effects of the membrane-anchored MMP regulator RECK on chondrogenic differentiation of ATDC5 cells

Shunya Kondo, Chisa Shukunami, Yoko Morioka, Naoya Matsumoto, Rei Takahashi, Junseo Oh, Tadao Atsumi, Akihiro Umezawa, Akira Kudo, Hitoshi Kitayama …

JOURNAL OF CELL SCIENCE 120(5) 849-857 2007年3月査読有り
Functional genomics reveals genes involved in protein secretion and Golgi organization

F Bard, L Casano, A Mallabiabarrena, E Wallace, K Saito, H Kitayama, G Guizzunti, Y Hu, F Wendler, R DasGupta …

NATURE 439(7076) 604-607 2006年2月査読有り
Histone deacetylase inhibitor FK228 suppresses the Ras-MAP kinase signaling pathway by upregulating Rap1 and induces apoptosis in malignant melanoma

Y Kobayashi, M Ohtsuki, T Murakami, T Kobayashi, K Sutheesophon, H Kitayama, Y Kano, E Kusano, H Nakagawa, Y Furukawa

ONCOGENE 25(4) 512-524 2006年1月査読有り
The membrane-anchored MMP-regulator RECK is a target of myogenic regulatory factors

M Echizenya, S Kondo, R Takahashi, J Oh, S Kawashima, H Kitayama, C Takahashi, M Noda

ONCOGENE 24(38) 5850-5857 2005年9月査読有り
Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK

J Oh, DW Seo, T Diaz, BY Wei, Y Ward, JM Ray, Y Morioka, SL Shi, H Kitayama, C Takahashi …

CANCER RESEARCH 64(24) 9062-9069 2004年12月査読有り
Rap1 mutants with increased affinity for the guanine-nucleotide exchange factor C3G

SL Shi, M Noda, H Kitayama

ONCOGENE 23(54) 8711-8719 2004年11月査読有り
Effects of RAS and RAP1 on electrical excitability of differentiated NG108-15 cells

Y Imamura, N Matsumoto, S Kondo, H Kitayama, M Noda

NEUROSCIENCE 127(4) 973-981 2004年査読有り
Possible involvement of Rap I and Ras in glutamatergic synaptic transmission

Y Imamura, N Matsumoto, S Kondo, H Kitayama, M Noda

NEUROREPORT 14(9) 1203-1207 2003年7月査読有り
RECK: A novel suppressor of malignancy linking oncogenic signaling to extracellular matrix remodeling

M Noda, J Oh, R Takahashi, S Kondo, H Kitayama, C Takahashi

CANCER AND METASTASIS REVIEWS 22(2-3) 167-175 2003年6月査読有り
Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies

M Ihara, H Tomimoto, H Kitayama, Y Morioka, Akiguchi, I, H Shibasaki, M Noda, M Kinoshita

JOURNAL OF BIOLOGICAL CHEMISTRY 278(26) 24095-24102 2003年6月査読有り
Isolation of a set of genes expressed in the choroid plexus of the mouse using suppression subtractive hybridization

N Matsumoto, H Kitayama, M Kitada, K Kimura, M Noda, C Ide

NEUROSCIENCE 117(2) 405-415 2003年査読有り

もっとみる

MISC

Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK

C Takahashi, ZQ Sheng, TP Horan, H Kitayama, M Maki, K Hitomi, Y Kitaura, S Takai, RM Sasahara, A Horimoto …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(22) 13221-13226 1998年10月査読有り
GENETIC-ANALYSIS OF THE KIRSTEN-RAS-REVERTANT-1 GENE - POTENTIATION OF ITS TUMOR SUPPRESSOR ACTIVITY BY SPECIFIC POINT MUTATIONS

H KITAYAMA, T MATSUZAKI, Y IKAWA, M NODA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(11) 4284-4288 1990年6月査読有り
DETECTION OF GENES WITH A POTENTIAL FOR SUPPRESSING THE TRANSFORMED PHENOTYPE ASSOCIATED WITH ACTIVATED RAS GENES

M NODA, H KITAYAMA, T MATSUZAKI, Y SUGIMOTO, H OKAYAMA, RH BASSIN, Y IKAWA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(1) 162-166 1989年1月査読有り

書籍等出版物

Krev-1 and the Related Genes (共著)

北山仁志

CRC Press "THE ras SUPERFAMILY of GTPases", 1993年

北山仁志

基本情報

研究分野

学歴

受賞

論文

MISC

書籍等出版物

所属学協会

共同研究・競争的資金等の研究課題

メニュー