UENO Hiroshi

J-GLOBAL         Last updated: Jul 12, 2019 at 07:36
UENO Hiroshi
Ryukoku University
Faculty of Agriculture
Job title
Ph.D.(Iowa State University Graduate School), M.A.(Brandeis University Graduate School), B.E.(Kyoto University)
Other affiliation
Nara Women's University

Research Areas


Academic & Professional Experience

Nara Women's University
:Rockefeller University, Research Associate (Stanford Moore-James Manning Laboratory)
:Rockefeller Foundation Fellow, Rockefeller University
:Woods Hole Marine Biological Laboratory Summer Investigator
:Rockefeller University, Assistant Professor


Biochemistry (David E. Metzler Laboratory), Iowa State University

Awards & Honors

International Congress on Vitamins, Coenzymes, and Biofactors, Best poster presentation award
Rockefeller Foundation Fellow

Published Papers

Activation of GABA synthetic enzyme, glutamate decarboxylase 67 by spice that leads to ther eduction of salt and elucidation of salty taste signaling mechanism
UENO Hiroshi
Science Impact   2019 71-73   2019   [Refereed][Invited]
Effects of cooking methods on free amino acid contents in vegetables
Ito, H., Kikuzaki, H. and Ueno, H.
J. Nutr. Sci. Vitam.   65 264-271   2019   [Refereed]
The ellagitannin trimer rugosin G inhibits recombinant human histidine decarboxylase
Nitta, Y., Ito, H., Komori, H., Ueno, H., Takeshima, D., Ito, M., Sakaue, M. and Kikuzaki, H.
Biosci. Biotech. Biochem.   83 1315-1318   2019   [Refereed]
Carboxypeptidase Y activity and maintenance is modulated by a large helical structure
Makino, M., Sahara, T., Morita, N. and Ueno, H.
FEBS Open Bio   9 1337-1343   2019   [Refereed]
Inhibition of Morganella morganii histidine decarboxylase activity and histamine accumulation in mackerel muscle derived from Filipendula ulumaria extracts
Nitta, Y., Yasukata, F., Kitamoto, N., Ito, M., Sakaue, M., Kikuzaki, H. and Ueno, H.
J. Food Protection   79 463-467   2017   [Refereed]
Construction of a free-form amino acid database for vegetables and mushrooms
Ito, H, Ueno, H. and Kikuzaki, H.
Integrative Food, Nutrition & Metabolism   4 1-9   2017   [Refereed]
Novel inhibitors for histidine decarboxylase from plant components
Nitta, Y., Kikuzaki, H. and Ueno, H.
Int. Biol. Rev.   1 1-14   2017   [Refereed]
Characterization of auxiliary iron-sulfur clusters in a radical S-adenosylmethionine enzyme PqqE from Methylobacterium extorquens AM1
Saichana, N., Tanizawa, K., Ueno, H., Pechousek, Jiri, Novak, P. and Frebortova, J.
Febs Open Bio   7 1864-1879   2017   [Refereed]
Free amino acid compositions for fruits
Ito, H., Ueno, H. and Kikuzaki, H.
J. Nutr. Diet. Prac.   1 001-005   2017   [Refereed]


Relationship between GAD/GABA and sweet, umami and bitter tastes, those received in type II taste buds
UENO Hiroshi
J. Biol. Macromol.   in press   2014
Construction of free amino acids composition data base for food
UENO Hiroshi
J. Chem. Chem. Eng.   in press   2014
Screening and identification of food extracts that are useful for reducing salt intake ? An approach from a GABA-synthesizing enzyme ?
UENO Hiroshi
J. Biol. Macromol.   14 in press   2014
Amino acid substitution reveals the role of V-shape helix on construction of yeast carboxypeptidase Y
UENO Hiroshi
J. Biol. Macromol.   14 in press   2014
UENO Hiroshi
J. Biol. Macromol   13 33-38   2013

Books etc

Glutamate decarboxylase in Amino acids in human nutrition and health
CABI   2011   
Study of regulatory properties of spice and herb extracts on glutamate decarboxylase and site-specific expression of glutamate decarboxylase in digestive system.
Proceedings of 3rd China-Japan International Conference on Vitamins   2004   
Effect of glycosylation on the mechanism of renaturation of carboxypeptidase Y
Trends in High Pressure Bioscience and Biotechnology (Hayashi, R., ed.), Elsevier Science B.V., Amsterdam   2002   
Use of high pressure to investigate the role of carbohydrate moiety in the conformational stability of carboxypeptidase Y
Advances in High Pressure Bioscience & Biotechnology (Ludwig, H., ed.), Springer, Heidelberg   1999   
The single cysteinyl residue (Cys341) of carboxypeptidase Y for cavity control in the S1 substrate binding pocket
Advances in High Pressure Bioscience & Biotechnology (Ludwig, H., ed.), Springer, Heidelberg   1999   

Conference Activities & Talks

Establishment of database for free amino acids in food
40th International Symposium on High Performance Liquid Phase Separations and Related Techniques   2013   
Quantitative amino acid analysis of free amino acids in food
Asianalysis XII   2013   
Amino acid substitution reveals the role of V-shape helix on substrate specificity of yeast carboxypeptidase Y
27th Protein Society Annual Symposium   2013   
Structural basis for the histamine synthesis by human histidine decarboxylase
AsCA 12/CRYSTAL 28 Conference and BRAGG Symposium   2012   


Study of GABA on taste mechanism