Akiko Kita

Profile Information

Affiliation: Assistant Professor,Assistant Professor, Research Reactor Institute, Research Reactor Institute Division of Quantum Beam Material Science, Kyoto University

Degree: Doctor of Science(Tokyo Institute of Technology)

J-GLOBAL ID: 200901075842211539
researchmap Member ID: 1000182337

Research Interests

Research Areas

Life sciences / Structural biochemistry /

Research History

Apr, 2018 - Present

Assistant professor, Institute for Integrated Radiation and Nuclear Science, Kyoto Univ.
Apr, 2007 - Mar, 2018

Assistant professor, Research Reactor Inst., Kyoto Univ.
Apr, 2006 - Mar, 2011

Visiting Researcher, HARIMA Institute,, RIKEN
Apr, 2004 - Mar, 2007

Assistant Professor (Research Reactor Institute, Kyoto Univ., present post), Research Reactor Inst., Kyoto Univ.
Oct, 1999 - Mar, 2006

Co-Researcher, HARIMA Institute,, RIKEN
May, 2004 - Sep, 2004

Assistant Professor (Graduate School of Science, Kyoto Univ., additional post), Graduate school of science,, Kyoto Univ.
Apr, 1995 - Mar, 2003

Assistant Professor (Graduate School of Science, Kyoto Univ.), Graduate school of science,, Kyoto Univ.
May, 1999 - Sep, 1999

Visiting Researcher, HARIMA Institute,, RIKEN
Apr, 1992 - Mar, 1995

Research Fellowships for Young Scientists (DC1)

Education

Apr, 1992 - Mar, 1995

Dept. of Electronic Chemistry, Graduate School of Integrated Science and Engineering, Tokyo Institute of Technology
Apr, 1990 - Mar, 1992

Dept. of Applied Precision Chemistry, Graduate School of Engineering, Osaka University
Apr, 1986 - Mar, 1990

Dept. of Applied Precision Chemistry, Faculty of Engineering, Osaka University

Committee Memberships

Mar, 2024 - Present

近畿支部幹事, 日本化学会
Sep, 2023 - Present

プログラム委員, 令和6年(2024年)度日本結晶学会年会
Apr, 2021 - Nov, 2021

日本結晶学会令和３年(2021年）度年会プログラム委員, 日本結晶学会
Jul, 2019 - Oct, 2019

executive committee, ISDSB2019
Jun, 2005 - May, 2006

年会実行委員, 第６回蛋白質科学会
Apr, 2000 - Mar, 2002

編集委員, 日本結晶学会

Awards

May, 2006

Morita Science Research Award, Japanese Association of University Women
Dec, 2002

Young Researcher Award, The Crystallographic Society of Japan

Major Papers

Crystal structure of GTP‐dependent dephospho‐coenzyme A kinase from the hyperthermophilic archaeon, Thermococcus kodakarensis

A. Kita, Y. Ishida, T. Shimosaka, Y. Michimori, K. Makarova, E. Koonin, H. Atomi, K. Miki

Proteins: Structure, Function, and Bioinformatics, Jan 18, 2024 Peer-reviewedLead authorCorresponding author
Structural basis of the 24B3 antibody against the toxic conformer of amyloid β with a turn at positions 22 and 23

Y. Irie, Y. Matsushima, A. Kita, K. Miki, T. Segawa, M. Maeda, R. C. Yanagita, K. Irie

Biochem. Biophys. Res. Commun., 621 162-167, Sep, 2022 Peer-reviewed
Hydrogen/Deuterium Exchange Behavior During Denaturing/Refolding Processes Determined in Tetragonal Hen Egg-White Lysozyme Crystals

A. Kita, Y. Morimoto

Mol Biotechnol., 64 590-597, Jan, 2022 Peer-reviewedLead author
Characterization of a Conformation-Restricted Amyloid β Peptide and Immunoreactivity of Its Antibody in Human AD brain

Y. Kageyama, Y. Irie, Y. Matsushima, T. Segawa, J-P Bellier, K. Hidaka, H. Sugiyama, D. Kaneda, Y. Hashizume, H. A …

ACS Chem. Neurosci., 12(18) 3418-3432, Aug 31, 2021 Peer-reviewed
Crystal structure of pantoate kinase from Thermococcus kodakarensis

A. Kita, A. Kishimoto, T. Shimosaka, H. Tomita, Y. Yokooji, T. Imanaka, H. Atomi, K. Miki

Proteins: Structure, Function, and Bioinformatics, 88(5) 718-724, May, 2020 Peer-reviewedLead authorCorresponding author
Hydrogen/deuterium exchange behavior in tetragonal hen egg-white lysozyme crystals affected by solution state

A. Kita, Y. Morimoto

J. Appl. Cryst., 53(3) 837-840, Apr, 2020 Peer-reviewedLead authorCorresponding author
Crystal structure of octocoral lectin SLL-2 complexed with Forssman antigen tetrasaccharide

A. Kita, M. Jimbo, R. Sakai, Y. Morimoto, R. Takeuchi, H. Tanaka, T. Takahashi, K. Miki

Glycobiology, 27(8) 696-700, Aug, 2017 Peer-reviewedLead authorCorresponding author
Inhibitory effects of local anesthetics on the proteasome and their biological actions

U. Bahrudin, M. Unnoa, K. Nishio, A. Kita, P. Li, M. Kato, M. Inoue, S. Tsujitani, T. Murakami, R. Sugiyama …

Sci. Rep., 7 5079, Jul, 2017 Peer-reviewed
An Effective Deuterium Exchange Method for Neutron Crystal Structure Analysis with Unfolding-Refolding Processes.

A. Kita, Y. Morimoto

Mol. Biotechnol., 58(2) 130-136, Feb, 2016 Peer-reviewedLead authorCorresponding author
In-situ and real-time growth observation of high-quality protein crystals under quasi-microgravity on earth

A. Nakamura, J. Ohtsuka, T. Kashiwagi, N. Numoto, N. Hirota, T. Ode, H. Okada, K. Nagata, M. Kiyohara, E. Suzuki …

Sci. Rep., 6 22127, Feb, 2016 Peer-reviewed
Evaluation of molecular perturbation of a deuterated protein by temperature factor refinement in X-ray structural analysis of high-resolution diffraction data

T. Uemura, A. Kita, Y. Morimoto

J. Biotechnol. Biomater., 6(233) 3255-952X, 2016 Peer-reviewed
The catalytic mechanism of decarboxylative hydroxylation of salicylate hydroxylase revealed by crystal structure analysis at 2.5 angstrom resolution

T. Uemura, A. Kita, Y. Watanabe, M. Adachi, R. Kuroki, Y. Morimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 469(2) 158-163, Jan, 2016 Peer-reviewed
Crystal structure of a symbiosis-related lectin from octocoral

A. Kita, M. Jimbo, R. Sakai, Y. Morimoto, K. Miki

Glycobiology, 25(9) 1016-1023, Sep, 2015 Peer-reviewedLead authorCorresponding author
Crystal structure of phosphopantothenate synthetase from Thermococcus kodakarensis

A. Kishimoto, A. Kita, T. Ishibashi, H. Tomita, Y. Yokooji, T. Imanaka, H. Atomi, K. Miki

Proteins: Structure, Function, and Bioinformatics, 82(9) 1924-1936, Sep, 2014 Peer-reviewed
The Structure of a deoxygenated 400 kDa hemoglobin provides a more accurate description of the cooperative mechanism of giant hemoglobins

N. Numoto, T. Nakagawa, R. Ohara, T. Hasegawa, A. Kita, T. Yoshida, T. Maruyama, K. Imai, Y. Fukumori, K. Miki

Acta Crystallogr. D, 70(7) 1823-1831, Jul 1, 2014 Peer-reviewed
Observation of the orientation of membrane protein crystals grown in high magnetic force fields

N. Numoto, K Shimizu, K. Matsumoto, K. Miki, A. Kita

J. Cryst. Growth, 367 53-56, Mar, 2013 Peer-reviewedCorresponding author
A detailed biochemical characterization of phosphopantothenate synthetase, a novel enzyme involved in coenzyme A biosynthesis in the Archaea

T. Ishibashi, H. Tomita, Y. Yokooji, T. Morikita, B. Watanabe, J. Hiratake, A. Kishimoto, A. Kita, K. Miki, T. Imanaka …

Extremophiles, 16(6) 819-828, Nov, 2012 Peer-reviewed
A P39R mutation at the N-terminal domain of human alpha B-crystallin regulates its oligomeric state and chaperone-like activity

Nobutaka Numoto, Akiko Kita, Noriko Fujii, Kunio Miki

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 425(3) 601-606, Aug, 2012 Peer-reviewedCorresponding author
Structural features of isomerizable aspartyl residues in human alpha-crystallins

Ken-ichi Shimizu, Akiko Kita, Noriko Fujii, Kunio Miki

MOLECULAR VISION, 18(187-90) 1823-1827, Jul, 2012 Peer-reviewedCorresponding author
Crystal structure of 3-hexulose-6-phosphate synthase, a member of the orotidine 5 '-monophosphate decarboxylase suprafamily

Izumi Orita, Akiko Kita, Hiroya Yurimoto, Nobuo Kato, Yasuyoshi Sakai, Kunio Miki

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 78(16) 3488-3492, Dec, 2010 Peer-reviewed
Crystal structure of PH1733, an aspartate racemase homologue, from Pyrococcus horikoshii OT3

A. Kita, S. Tasaki, M. Yohda, K. Miki

Proteins: Structure, Function, and Bioinformatics, 74(1) 240-244, Jan, 2009 Peer-reviewedLead author
Structural Basis for the Heterotropic and Homotropic Interactions of Invertebrate Giant Hemoglobin

N. Numoto, T. Nakagawa, A. Kita, Y. Sasayama, Y. Fukumori, K. Miki

Biochemistry, 47(43) 11231-11238, Oct, 2008 Peer-reviewed
Structure of the partially unliganded met state of 400 kDa hemoglobin: Insights into ligand-induced structural changes of giant hemoglobins

N. Numoto, T. Nakagawa, A. Kita, Y. Sasayama, Y. Fukumori, K. Miki

Proteins: Structure, Function, and Bioinformatics, 73(1) 113-125, Oct, 2008 Peer-reviewed
Crystal structure of the [2Fe-2S] oxidative-stress sensor SoxR bound to DNA

S. Watanabe, A. Kita, K. Kobayashi, K. Miki

PNAS, 105(11) 4121-4126, Mar 18, 2008 Peer-reviewed
Structure and molecular dynamics simulation of archaeal prefoldin: The molecular mechanism for binding and recognition of nonnative substrate proteins

A. Ohtaki, H. Kida, Y. Miyata, N. Ide, A. Yonezawa, T. Arakawa, R. Iizuka, K. Noguchi, A. Kita, M. Odaka …

J. Mol. Biol., 376(4) 1130-1141, Feb, 2008 Peer-reviewed
Crystallographic study on the interaction of L-lactate oxidase with pyruvate at 1.9 angstrom resolution

Shu Jie Li, Yasufumi Umena, Kazuko Yorita, Takeshi Matsuoka, Akiko Kita, Kiyoshi Fukui, Yukio Morimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 358(4) 1002-1007, Jul, 2007 Peer-reviewed

Major Misc.

165

Deuterated/undeuterated positions in denatured/refolded hen egg lysozyme.

Akiko Kita, Yukio Morimoto

Proceedings of the 56th KURNS Scientific Meeting, 31-31, Feb, 2022 Lead author
Neutron structure analysis of the deuterated denatured/refolded protein crystals

Akiko Kita, Yukio Morimoto

Proceedings of the 55th KURNS Scientific Meeting, 24-24, Feb, 2021 Lead author
Neutron crystallographic studies for deuterated protein that reflects the solvent state

Akiko Kita, Yukio Morimoto

Proceedings of the 54th KURNS Scientific Meeting, 41-41, Feb, 2020 Lead author
Elucidation of denatured protein using deuteration.

Akiko Kita

Proceedings of the 53th KURNS Scientific Meeting, 47-48, Feb, 2019 Invited
Structure analysis of enzymes required for the distinct CoA production pathway in hyperthermophilic archaea.

Akiko Kita, Asako Kishimoto, Takahiro Shimosaka, Takuya Ishibashi, Hiroya Tomita, Yuusuke Yokooji, Tadayuki Imanaka, Haruyuki Atomi, Kunio Miki

Proceedings of the 52th KURRI Scientific Meeting., 32-32, Jan, 2018 Lead author
A study of preparation and structural analysis of the organomercury lyase for a neutron diffraction experiment.

Yukio Morimoto, Akiko Kita

Proceedings of the 52th KURRI Scientidif Meeting., 19-19, Jan, 2018
変性重水素化リゾチームの中性子結晶構造解析

喜田昭子, 森本幸生

平成29年度日本中性子科学会第17回年会, Dec, 2017 Lead author
変性状態を利用した重水素化タンパク質結晶の中性子線回折実験の試み

喜田昭子, 森本幸生

日本結晶学会年会, Oct, 2017 Lead author
アーキアの補酵素A生合成経路に固有の酵素群の構造解析

喜田昭子, 岸本麻子, 下坂天洋, 石橋拓也, 冨田宏矢, 横大路裕介, 今中忠行, 跡見晴幸, 三木邦夫

第17回日本蛋白質科学会年会, (20), Jun, 2017 Lead author
アーキアの補酵素A生合成経路に固有の酵素群の構造解析

喜田昭子, 岸本麻子, 下坂天洋, 石橋拓也, 冨田宏矢, 横大路裕介, 今中忠行, 跡見晴幸, 三木邦夫

日本蛋白質科学会年会プログラム・要旨集, 17th, 2017 Lead author
サンゴ由来レクチン４糖複合体の結晶構造

喜田昭子, 神保充, 酒井隆一, 森本幸生, 武内良太, 田中浩士, 高橋孝志, 三木邦夫

京都大学原子炉実験所第51回学術講演会, Jan, 2017 Lead author
Crystal structure of symbiosis related lectin SLL-2 in complex with tetrasaccharides.

A. Kita, M. Jimbo, R. Sakai, Y. Morimoto, R. Takeuchi, H. Tanaka, T. Takahashi, K. Miki

14th conference of Asian Crystallographic Association, Dec, 2016 Lead author
共生に関与する珊瑚由来レクチンの４糖糖鎖結合様式

喜田昭子, 神保充, 酒井隆一, 森本幸生, 武内良太, 田中浩士, 高橋孝志, 三木邦夫

平成28年度日本結晶学会年会, 2016, Nov, 2016 Lead author
Crystallographic studies of two enzymes required for the distinct CoA production pathway in archaea.

A. Kita, A. Kishimoto, T. Shimosaka, T. Ishibashi, H. Tomita, Y. Yokooji, T. Imanaka, H. Atomi, K. Miki

Extremophiles 2016, Sep, 2016 Lead author
カテコール産生における脱炭酸・水酸基付加反応の考察-サリチル酸水酸化酵素の結晶構造解析から-

上村拓也, 喜田昭子, 足立基泰, 黒木良太, 森本幸生

京都大学原子炉実験所第50回学術講演会, Jan, 2016
結晶解析のための、効率的なタンパク質の重水素化

喜田昭子, 森本幸生

京都大学原子炉実験所第50回学術講演会, Jan, 2016 Lead author
変性状態を利用したタンパク質の重水素化変性状態を利用したタンパク質の重水素化

喜田昭子, 森本幸生

日本結晶学会年会, Oct, 2015 Lead author
有機水銀分解酵素の中性子構造解析のための試料調製および結晶化

森本幸生, 上村拓也, 喜田昭子, 三木邦夫

日本結晶学会年会, Oct, 2015
サリチル酸水酸化酵素・基質複合体の結晶構造解析

上村拓也, 喜田昭子, 安達基泰, 黒木良太, 森本幸生

第15回日本蛋白質科学会年会, Jun, 2015
蛋白質分子内のプロトン・プロトン化の直接観察

森本幸生, 山口宏, 細川桂一, 村上琢人, 喜田昭子, 海野昌喜, 久留一郎, 茶竹俊行, 柳澤泰任, 藤原悟 …

KURRI-KR, (200), 2015
結晶解析のためのタンパク質の重水素化

喜田昭子, 森本幸生

京都大学原子炉実験所第49回学術講演会, Jan, 2015 Lead author
牛肝臓カタラーゼの重水調整結晶による構造解析

上村拓也, 喜田昭子, 森本幸生

京都大学原子炉実験所第49回学術講演会, Jan, 2015
巨大ヘモグロビン結晶中での酸素解離に伴う構造変化

沼本修孝, 中川太郎, 喜田昭子, 伊藤暢聡, 福森義宏, 三木邦夫

日本結晶学会平成26年度年会, Nov, 2014
Transition from oxy to deoxy state in crystalline giant hemoglobin

N. Numoto, T. Nakagawa, A. Kita, N. Ito, Y. Fukumoti, K. Miki

The 52th Annual Meeting of The Biophysical Society of Japan, Sep, 2014
Weak interaction of an inhibitor in the 20S proteasome.

T. Murakami, H. Yamaguchi, U. Bahrudin, A. Kita, U. Hisatome, Y. Saeki, K. Tanaka, M. Unno, Y. Morimoto

The 23rd Congress and General Assembly of the International Union of Crystallography, Aug, 2014
Partial oxygen-dissociation of crystalline giant hemoglobin.

N. Numoto, T. Nakagawa, A. Kita, N. Ito, Y. Fukumori, K. Miki

The 23rd Congress and General Assembly of the International Union of Crystallography, Aug, 2014
Crystal structure of archaeal phosphopantothenate synthetase.

A. Kita, A. Kishimoto, T. Ishibashi, H. Yomita, Y. Yokooji, T. Imanaka, H. Atomi, K. Miki

The 23rd Congress and General Assembly of the International Union of Crystallography, Aug, 2014 Lead author
巨大ヘモグロビン結晶内における酸素解離過程

沼本修孝, 中川太郎, 喜田昭子, 伊藤暢聡, 福森義宏, 三木邦夫

第14回日本蛋白質科学会年会, Jun, 2014
共生に関与するサンゴ由来レクチンの結晶構造

喜田昭子, 神保充, 酒井隆一, 森本幸生, 武内良太, 田中浩士, 高橋孝志, 三木邦夫

第48回京都大学原子炉実験所学術講演会, (193), Jan, 2014 Lead author
Implications for quinone cofactor biogenesis in amine-oxidizing enzymes

A. Kita, M. Mure, K. Miki

SPring-8/SACLA Research Report,, 2014 Peer-reviewedLead author
中性子結晶構造解析取り組みについて

喜田昭子, 森本幸生

大阪大学タンパク研セミナー, Dec, 2013 Invited
巨大ヘモグロビン結晶中での酸素結合状態の操作

沼本修孝, 中川太郎, 喜田昭子, 伊藤暢聡, 福森義宏, 三木邦夫

平成25年度日本結晶学会年会, Oct, 2013
Thermococcus kodakarensis由来ホスホパントテン酸合成酵素の基質複合体の結晶構造解析

岸本麻子, 喜田昭子, 石橋拓也, 冨田宏矢, 横大路裕介, 跡見晴幸, 三木邦夫

第86回日本生化学会大会, 86th, Sep, 2013
Observations of the protein crystal growth in high magnetic forces fields.

A. Kita, N. Numoto, K. Shimizu, K. Matsumoto, K. Miki

Structural Life Science International Conference on Structural Genomics 2013 (ICSG2013), Aug, 2013 Lead author
膜タンパク質結晶化における強磁気力場の効果

沼本修孝, 喜田昭子

第13回日本蛋白質科学会年会, Jun, 2013
超好熱性アーキア由来ホスホパントテン酸合成酵素基質複合体のX線結晶構造解析

岸本麻子, 喜田昭子, 石橋拓也, 冨田宏矢, 横大路祐介, 跡見晴幸, 三木邦夫

第13回日本蛋白質科学会年会, 13th, Jun, 2013
軟サンゴ由来レクチンと直鎖多糖の複合体の結晶構造

喜田昭子, 神保充, 森本幸生, 竹内良太, 田中浩士, 高橋孝志, 三木邦夫

第13回日本蛋白質科学会年会, 13th, Jun, 2013 Lead author
超好熱性アーキアThermococcus kodakarensis由来ホスホパントテン酸合成酵素の結晶構造

岸本麻子, 喜田昭子, 石橋拓也, 冨田宏矢, 横大路裕介, 跡見晴幸, 三木邦夫

物構研サイエンスフェスタ要旨集, 1st, 2013
高品質結晶生成を目指した、磁気力場中でのタンパク質結晶化

沼本修孝, 喜田昭子

第47回京都大学原子炉実験所学術講演会, Jan, 2013
超伝導マグネットを用いた高効率･高品位タンパク質結晶生成システムの開発と産業用酵素への適用

柏木立己, 高橋一敏, 山本麻以, 石川弘紀, 鈴木基孝, 横山敬一, 田口精一, 鈴木榮一郎, 田之倉優, 中村顕 …

平成23年度日本結晶学会年会, Nov, 2012
サツマハオリムシ400 kDaヘモグロビンのoxy型とdeoxy型構造の比較

沼本修孝, 中川太郎, 喜田昭子, 福森義宏, 三木邦夫

平成23年度日本結晶学会年会, Nov, 2012
Development of the system for high throughput high quality protein crystal growth using high magnetic forces.

N. Hirota, H. Wada, M. Kiyohara, M. Tanokura, A. Kita, E. Suzuki, H. Okada, T. Ode, A. Nakamura, J. Ohtsuka …

International Conference of the Asian Union of Magnetics Societies, Oct, 2012
超好熱性アーキア由来ホスホパントテン酸合成酵素の結晶構造解析

岸本麻子, 喜田昭子, 石橋拓也, 冨田宏矢, 横大路祐介, 跡見晴幸, 三木邦夫

平成24年度日本結晶学会年会, 2012, Oct, 2012
強磁気力場を利用したタンパク質結晶化とその影響

沼本修孝, 喜田昭子

平成24年度日本結晶学会年会, Oct, 2012
Crystallization behaviors of protein molecules in high magnetic forces fields

N. Numoto, A. Kita

The 27 th European Crystallographic Meeting (ECM27), Aug, 2012
ヒトαBクリスタリンP39R変異体の会合状態および凝集抑制活性に与える効果

沼本修孝, 喜田昭子, 藤井紀子

第12回日本蛋白質科学会年会, Jun, 2012
超好熱性アーキアのホスホパントテン酸合成酵素の結晶構造

岸本麻子, 喜田昭子, 石橋拓也, 冨田宏矢, 横大路裕介, 跡見晴幸, 三木邦夫

第12回日本蛋白質科学会年会, 12th, Jun, 2012
磁気力場のタンパク質結晶化への影響

喜田昭子, 沼本修孝

第12回日本蛋白質科学会年会, Jun, 2012 Lead author
Development of he device for high throughput high quality protein crystal growth using high magnetic forces with the aid of optical microscope

N. Hirota, H. Wada, M. Kiyohara, M. Tanokura, A. Kita, E. Suzuki, H. Okada, T. Ode, A. Nakamura, J. Ohtsuka …

5th International Workshop on Material Analysis and Proceeding in Magnetic Fields, May, 2012
αクリスタリンにおける異性化アスパラギン酸残基の分子内環境

清水健一, 喜田昭子, 藤井紀子, 三木邦夫

京都大学原子炉実験所第46回学術講演会, Feb, 2012

Books and Other Publications

日本の結晶学II

喜田昭子 (Role: Contributor, 第5章タンパク質結晶学,「serine/threonine protein phosphatase 1触媒サブユニット(PP1C)-阻害剤複合体」)

日本結晶学会, Jul, 2014
私が研究者になるまで

喜田昭子

学術の動向4月号, pp.72-73, Apr, 2007
実験化学講座11 物質の構造III 回折 5生体高分子の結晶構造ー5.2結晶化とＸ線回折実験ー5.2.1結晶化法

喜田昭子 (Role: Contributor)

日本化学会編, 2006
ゲノミクス・プロテオミクスの新展開〜生物情報の解析と応用第２章第２節・Ｘ線結晶構造解析「タンパク質の結晶化」，今中忠行監修，pp. 596-600

喜田昭子 (Role: Contributor)

エヌ・ティー・エス, 2004

Major Presentations

重水内で変性後に再生操作を行ったリゾチームの,中性子線結晶解析で明らかになった重水素置換位置

喜田昭子, 森本幸生

第４８回生体分子科学討論会, Jun 30, 2022
重水内で変性/再生操作を行ったニワトリ卵白リゾチームの水素/重水素置換部位

喜田昭子, 森本幸生

令和３年（2021年）度日本結晶学会年会, Nov 19, 2021
Neutron crystal structure analysis of denatured/refolded hen egg lysozyms.

A. Kita, Y. Morimoto

CrSJ Annual Meeting and General Assembly 2020, 70th Anniversary, Nov, 2020
Structural analysis of ligand binding mechanism of L-lactate oxidase from Aerococcus viridans by use of ligand soaking crystals

Y. Morimoto, N. Furubayashi, M. Kamo, Y. Umena, A. Kita, T. Matsuoka, K. Inaka

16th Conference of the Asian Crystallographic Association (AsCA2019), Dec 17, 2019
Hydrogen/deuterium exchange behavior in tetragonal hen egg-white lysozyme crystals

Akiko Kita, Yukio Morimoto

16th Conference of the Asian Crystallographic Association (AsCA2019), Dec 17, 2019
重水内変性/再生試料に対するコントロールとしての，ニワトリ卵白リゾチームの中性子線結晶構造

喜田昭子, 森本幸生

日本結晶学会令和元年（2019年）度年会および総会, Nov 19, 2019
Hydrogen/deuterium exchange behavior in tetragonal hen egg-white lysozyme crystals analyzed by the neutron diffraction methods

Akiko Kita, Yukio Morimoto

International Symposium on Diffraction Structural Biology 2019, Oct, 2019
Elucidation of protein denaturation with neutron crystallography

Akiko Kita, Yukio Morimoto

Joint Annual Meeting of 71th JSCB and 19th PSSJ, Jun 24, 2019
Elucidation of denatured protein using deuteration.

Akiko Kita

Feb 5, 2019 Invited
The neutron structure analysis of the protein crystal deuterated with unfolding-refolding processes

Akiko Kita, Yukio Morimoto

AsCA2018/CRYSTAL32, Dec, 2018
Neutron diffraction studies of the protein crystal deuterated with unfolding-refolding processes

Akiko Kita, Yukio Morimoto

Annual Meeting 2018 and General Assembly, Crystallographic Society of Japan, Nov 11, 2018
アーキアの補酵素A生合成経路に固有のキナーゼの結晶構造解析

喜田昭子, 岸本麻子, 下坂天洋, 石橋拓也, 冨田宏矢, 横大路裕介, 今中忠行, 跡見晴幸, 三木邦夫

第18回日本蛋白質科学会年会, Jun, 2018
変性状態を利用した重水素化タンパク質結晶の中性子線回折実験の試み

喜田昭子, 森本幸生

平成29年度日本結晶学会年会, Nov 23, 2017
変性状態を利用したタンパク質の重水素化

喜田昭子, 森本幸生

平成27年度日本結晶学会年会, Oct 18, 2015
Protein deuterization for neutron crystallography

KITA Akiko

Jun 24, 2015 Invited
中性子結晶構造解析の取り組みについて-蛋白質の重水素化の評価と重水素化結晶の調整にむけて-

喜田昭子, 森本幸生

大阪大学タンパク研セミナー, Dec 17, 2013 Invited
Development of the system for high throughput high quality protein crystal growth using high magnetic forces

N. Hirota, H. Wada, M. Kiyohara, M. Tanokura, A. Kita, E. Suzuki, H. Okada, T. Ode, A. Nakamura, J. Ohtsuka, N. Numoto, T. Kashiwagi

International Conference of the Asian Union of Magnetics Societies, Oct 5, 2012
Development of the device for high throughput high quality protein crystal growth using high magnetic forces with the aid of optical microscope

KITA Akiko

5th International Workshop on materials Analysis and Processing in Magnetic Fields, May 13, 2012
サツマハオリムシ400 kDaヘモグロビンのoxy型とdeoxy型構造の比較

日本結晶学会2011年度年会, Nov 24, 2011
Application of High-Field Superconducting Magnet to Protein Crystallization

H. Wada, S. Matsumoto, M. Tanokura, N. Hirota, E. Suzuki, A. Kita, K. Kiyohara

Superconductivity Centennial Conference 2011, Sep 18, 2011
生体高分子の構造生物学的研究

喜田昭子

大学婦人教会守田科学研究奨励賞受賞講演, May 13, 2006 Invited
種結晶を使ったタンパク質の結晶化

喜田昭子

大阪大学タンパク研セミナー, Mar 11, 2006 Invited
Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1

KITA Akiko

Jun 2, 2004 Invited
酵素タンパク質反応の分子機構に関する結晶学的研究

喜田昭子

結晶学会平成14年度年会, Dec 2, 2002 Invited

Professional Memberships

Research Projects

Development to ultra-early diagnosis and prevention of AD by using a specific antibody against the toxic conformation of amyloid beta

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2023 - Mar, 2026
Very early diagnosis of Alzheimer's disease by the toxic oligomer specific antibody of amyloid beta

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2023
Novel Preventive Strategy for Alzheimer's Disease Based on the Toxic Conformation Theory of Amyloid beta

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (S), Japan Society for the Promotion of Science, May, 2014 - Mar, 2019

Irie Kazuhiro
The relationship between photoreception and structure change of the short BLUF (the sensor of Blue Light Using FAD) protein

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2007 - 2008

KITA Akiko
短鎖青色光受容体タンパク質のX線結晶構造解析

科学研究費助成事業, 若手研究(B), 日本学術振興会, 2005 - 2006

喜田昭子
Structure and Function of DNA Repair Enzyme and Their Homologous Proteins

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, 2002 - 2004

MIKI Kunio, KITA Akiko, FUJIHASHI Masahiro
細胞内酸化物ストレス応答システムの構造生物学的研究

科学研究費助成事業, 若手研究(B), 日本学術振興会, 2002 - 2003

喜田昭子
Elucidation of the structural and mechanistic basis of pollutants-and signal-transmitter-degrading dioxygenases and their directed evolution

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Priority Areas, Japan Society for the Promotion of Science, 2001 - 2003

HORIIKE Kihachiro, KIMURA Takahide, TANAKA Hiroyuki, ISHIDA Tetsuo, KITA Akiko
高エネルギーX線によるXe,Csを用いた多波長異常分散(MAD)法

科学研究費助成事業, 萌芽研究, 日本学術振興会, 2002 - 2002

三木邦夫, 竹田一旗, 宮武秀行, 喜田昭子
生体内不斉反応を触媒するアルデヒド還元酵素の構造生物学的研究

科学研究費助成事業, 奨励研究(A), 日本学術振興会, 2000 - 2001

喜田昭子
次世代大型放射光SPring-8での超分子タンパク質結晶学研究の確立

科学研究費助成事業, 萌芽的研究, 日本学術振興会, 1998 - 1998

三木邦夫, 北所健悟, 喜田昭子, 樋口芳樹
タンパク質結晶学による二原子酸素添加酵素の分子機構に関する構造化学的研究

科学研究費助成事業, 奨励研究(A), 日本学術振興会, 1997 - 1998

喜田昭子
次世代大型放射光SPring-8タンパク質結晶解析ビームラインの性能評価

科学研究費助成事業, 萌芽的研究, 日本学術振興会, 1997 - 1997

三木邦夫, 北所健悟, 喜多昭子, 樋口芳樹
Crystallographic Study of Molecular Mechanism of DNA Repair by Photolyase

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 1996 - 1997

MIKI Kunio, KITADOKORO Kengo, KITA Akiko, HIGUCHI Yoshiki
膜輸送タンパク質テトラサイクリン/プロトンアンチトランスポータの構造化学的研究

科学研究費助成事業, 奨励研究(A), 日本学術振興会, 1996 - 1996

喜田昭子
テトラサイクリン/プロトンアンチポ-タの結晶化とX線構造解析

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1996 - 1996

三木邦夫, 北所健悟, 喜田昭子, 樋口芳樹
タンパク質の立体構造に基づく超分子形成の分子機構の解明

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1996 - 1996

三木邦夫, 北所健悟, 喜田昭子, 樋口芳樹
テトラサイクリン/プロトンアンチポ-タの結晶化とX線構造解析

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1995 - 1995

三木邦夫, 喜田昭子
タンパク質の立体構造に基づく超分子形成の分子機構の解明

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1995 - 1995

三木邦夫, 喜田昭子
Studies on Molecular Mechanism of Bioluminescence

Grants-in-Aid for Scientific Research, Grant-in-Aid for General Scientific Research (B), Japan Society for the Promotion of Science, 1994 - 1995

MIKI Kunio, KITA Akiko

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