TAKEDA Atsushi

J-GLOBAL         Last updated: Feb 22, 2019 at 13:49
 

Research Areas

 
 

Academic & Professional Experience

 
Apr 2014
 - 
Today
Director, National Hospital Organization Sendai-Nishitaga Hospital
 
Oct 2013
 - 
Mar 2014
Deputy director, National Hospital Organization Sendai-Nishitaga Hospital
 
May 2007
 - 
Sep 2013
Associate Professor, Tohoku University Graduate School of Medicine, Department of Medical Sciences, Neuroscience and Sensory Organs,Neurology
 

Education

 
 
 - 
1992
Graduate School, Division of Medicine, Tohoku University
 
 
 - 
1985
Faculty of Medicine, Tohoku University
 

Committee Memberships

 
2009
   
 
- Movement Disorder Society, Japan Executive Committee
 
2008
 - 
2009
日本神経学会  評議員
 
2008
 - 
2009
日本神経学会  査読委員
 
2007
   
 
日本神経学会  評議員
 
2006
   
 
日本神経学会  評議員
 

Awards & Honors

 
2012
楢林賞
 

Published Papers

 
Baba T, Hosokai Y, Nishio Y, Kikuchi A, Hirayama K, Suzuki K, Hasegawa T, Aoki M, Takeda A, Mori E
Journal of the neurological sciences   372 288-293   Jan 2017   [Refereed]
Kuroda H, Mukai Y, Nishiyama S, Takeshita T, Tateyama M, Takeda A, Aoki M
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   34 234-236   Dec 2016   [Refereed]
Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Ezura M, Kobayashi M, Tano O, Mugikura S, Iwata R, Ishiki A, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
Neurology   87(22) 2309-2316   Nov 2016   [Refereed]
Yoshihara A, Fukatsu M, Hoshi K, Ito H, Nollet K, Yamaguchi Y, Ishii R, Tokuda T, Miyajima M, Arai H, Kato T, Furukawa K, Arai H, Kikuchi A, Takeda A, Ugawa Y, Hashimoto Y
Journal of biochemistry   160(2) 87-91   Aug 2016   [Refereed]
Odagiri H, Baba T, Nishio Y, Iizuka O, Matsuda M, Inoue K, Kikuchi A, Hasegawa T, Aoki M, Takeda A, Taki Y, Mori E
PloS one   11(4) e0152746   Apr 2016   [Refereed]
Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Kobayashi M, Miura E, Tanaka N, Tamai K, Furukawa K, Arai H, Mori F, Wakabayashi K, Aoki M, Itoyama Y, Takeda A
PloS one   6(12) e29460   2011   [Refereed]
Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M, Tanaka N
Scientific reports   6 24997   Apr 2016   [Refereed]
Kawasaki I, Baba T, Takeda A, Mori E
Parkinsonism & related disorders   22 74-79   Jan 2016   [Refereed]
Uchiyama M, Nishio Y, Yokoi K, Hosokai Y, Takeda A, Mori E
Parkinsonism & related disorders   21(6) 603-609   Jun 2015   [Refereed]
Miura E, Hasegawa T, Konno M, Suzuki M, Sugeno N, Fujikake N, Geisler S, Tabuchi M, Oshima R, Kikuchi A, Baba T, Wada K, Nagai Y, Takeda A, Aoki M
Neurobiology of disease   71 1-13   Nov 2014   [Refereed]
Shoji Y, Nishio Y, Baba T, Uchiyama M, Yokoi K, Ishioka T, Hosokai Y, Hirayama K, Fukuda H, Aoki M, Hasegawa T, Takeda A, Mori E
PloS one   9(10) e110547   Oct 2014   [Refereed]
Kashihara K, Kondo T, Mizuno Y, Kikuchi S, Kuno S, Hasegawa K, Hattori N, Mochizuki H, Mori H, Murata M, Nomoto M, Takahashi R, Takeda A, Tsuboi Y, Ugawa Y, Yamanmoto M, Yokochi F, Yoshii F, Stebbins GT, Tilley BC, Luo S, Wang L, LaPelle NR, Goetz CG, MDS-UPDRS Japanese Validation Study Group.
Movement disorders clinical practice   1(3) 200-212   Sep 2014   [Refereed]
Stankovic I, Krismer F, Jesic A, Antonini A, Benke T, Brown RG, Burn DJ, Holton JL, Kaufmann H, Kostic VS, Ling H, Meissner WG, Poewe W, Semnic M, Seppi K, Takeda A, Weintraub D, Wenning GK, Movement Disorders Society MSA (MODIMSA) Study Group.
Movement disorders : official journal of the Movement Disorder Society   29(7) 857-867   Jun 2014   [Refereed]
Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Miura E, Oshima R, Aoki M, Takeda A
Case reports in neurology   6(1) 92-95   Mar 2014   [Refereed]
Takeda A, Baba T, Kikuchi A, Hasegawa T, Sugeno N, Konno M, Miura E, Mori E
Journal of Parkinson's disease   4(2) 181-187   2014   [Refereed]
Kikuchi A, Baba T, Hasegawa T, Kobayashi M, Sugeno N, Konno M, Miura E, Hosokai Y, Ishioka T, Nishio Y, Hirayama K, Suzuki K, Aoki M, Takahashi S, Fukuda H, Itoyama Y, Mori E, Takeda A
BMJ open   3(3)    Mar 2013   [Refereed]
Kaneko K, Tano O, Kikuchi A, Hasegawa T, Tateyama M, Yoshioka M, Saito H, Watanabe O, Takeda A, Aoki M
Journal of neurology   260(1) 315-317   Jan 2013   [Refereed]
Konno M, Hasegawa T, Baba T, Miura E, Sugeno N, Kikuchi A, Fiesel FC, Sasaki T, Aoki M, Itoyama Y, Takeda A
Molecular neurodegeneration   7 38   Aug 2012   [Refereed]
Baba T, Kikuchi A, Hirayama K, Nishio Y, Hosokai Y, Kanno S, Hasegawa T, Sugeno N, Konno M, Suzuki K, Takahashi S, Fukuda H, Aoki M, Itoyama Y, Mori E, Takeda A
Brain : a journal of neurology   135(1) 161-169   Jan 2012   [Refereed]
Sawada Y, Nishio Y, Suzuki K, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Itoyama Y, Takahashi S, Fukuda H, Mori E
PloS one   7(6) e38498   2012   [Refereed]
Hiraoka K, Okamura N, Funaki Y, Hayashi A, Tashiro M, Hisanaga K, Fujii T, Takeda A, Yanai K, Iwata R, Mori E
European neurology   68(3) 137-143   2012   [Refereed]
Kanno S, Abe N, Saito M, Takagi M, Nishio Y, Hayashi A, Uchiyama M, Hanaki R, Kikuchi H, Hiraoka K, Yamasaki H, Iizuka O, Takeda A, Itoyama Y, Takahashi S, Mori E
Journal of neurology   258(11) 1949-1957   Nov 2011   [Refereed]
Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Takeda A
Parkinsonism & related disorders   17 698-700   Nov 2011   [Refereed]
Ishioka T, Hirayama K, Hosokai Y, Takeda A, Suzuki K, Nishio Y, Sawada Y, Takahashi S, Fukuda H, Itoyama Y, Mori E
Movement disorders : official journal of the Movement Disorder Society   26 837-843   Apr 2011   [Refereed]
Baba T, Takeda A, Kikuchi A, Nishio Y, Hosokai Y, Hirayama K, Hasegawa T, Sugeno N, Suzuki K, Mori E, Takahashi S, Fukuda H, Itoyama Y
Movement disorders : official journal of the Movement Disorder Society   26 621-628   Mar 2011   [Refereed]
Hasegawa T, Baba T, Kobayashi M, Konno M, Sugeno N, Kikuchi A, Itoyama Y, Takeda A
Neurochemistry international   57(8) 857-866   Dec 2010   [Refereed]
Nishio Y, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Suzuki K, Itoyama Y, Takahashi S, Mori E
European journal of neurology : the official journal of the European Federation of Neurological Societies   17 1090-1097   Aug 2010   [Refereed]
Kikuchi A, Takeda A, Okamura N, Tashiro M, Hasegawa T, Furumoto S, Kobayashi M, Sugeno N, Baba T, Miki Y, Mori F, Wakabayashi K, Funaki Y, Iwata R, Takahashi S, Fukuda H, Arai H, Kudo Y, Yanai K, Itoyama Y
Brain : a journal of neurology   133(6) 1772-1778   Jun 2010   [Refereed]
Takeda A, Saito N, Baba T, Kikuchi A, Sugeno N, Kobayashi M, Hasegawa T, Itoyama Y
Journal of the neurological sciences   289(1-2) 36-39   Feb 2010   [Refereed]
Kikuchi A, Takeda A, Itoyama Y
Internal medicine (Tokyo, Japan)   49 2711   2010   [Refereed]
Satake W, Nakabayashi Y, Mizuta I, Hirota Y, Ito C, Kubo M, Kawaguchi T, Tsunoda T, Watanabe M, Takeda A, Tomiyama H, Nakashima K, Hasegawa K, Obata F, Yoshikawa T, Kawakami H, Sakoda S, Yamamoto M, Hattori N, Murata M, Nakamura Y, Toda T
Nature genetics   41(12) 1303-1307   Dec 2009   [Refereed]
Petzold A, Brettschneider J, Jin K, Keir G, Murray NM, Hirsch NP, Itoyama Y, Reilly MM, Takeda A, Tumani H
Muscle & nerve   40 42-49   Jul 2009   [Refereed]
Abe N, Fujii T, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Nishio Y, Suzuki K, Itoyama Y, Takahashi S, Fukuda H, Mori E
Brain : a journal of neurology   132 1386-1395   May 2009   [Refereed]
Hosokai Y, Nishio Y, Hirayama K, Takeda A, Ishioka T, Sawada Y, Suzuki K, Itoyama Y, Takahashi S, Fukuda H, Mori E
Movement disorders : official journal of the Movement Disorder Society   24 854-862   Apr 2009   [Refereed]
Baba T, Nakashima I, Kanbayashi T, Konno M, Takahashi T, Fujihara K, Misu T, Takeda A, Shiga Y, Ogawa H, Itoyama Y
Journal of neurology   256 287-288   Feb 2009   [Refereed]
Sugeno N, Takeda A, Hasegawa T, Kobayashi M, Kikuchi A, Mori F, Wakabayashi K, Itoyama Y
The Journal of biological chemistry   283(34) 23179-23188   Aug 2008   [Refereed]
Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA
International journal of molecular sciences   9 789-806   May 2008   [Refereed]
Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G
Free radical biology & medicine   44 1493-1505   Apr 2008   [Refereed]
Suzuki N, Motohashi N, Uezumi A, Fukada S, Yoshimura T, Itoyama Y, Aoki M, Miyagoe-Suzuki Y, Takeda S
The Journal of clinical investigation   117 2468-2476   Sep 2007   [Refereed]
Hasegawa T, Sugeno N, Takeda A, Matsuzaki-Kobayashi M, Kikuchi A, Furukawa K, Miyagi T, Itoyama Y
FEBS letters   581(3) 406-412   Feb 2007   [Refereed]
Satake Wataru, Mizuta Ikuko, Suzuki Satoko, Nakabayashi Yuko, Ito Chiyomi, Watanabe Masahiko, Takeda Atsushi, Hasegawa Kazuko, Sakoda Saburo, Yamamoto Mitsutoshi, Hattori Nobutaka, Murata Miho, Toda Tatsushi
Neuroreport   18(9) 937-940   2007
Furukawa K, Matsuzaki-Kobayashi M, Hasegawa T, Kikuchi A, Sugeno N, Itoyama Y, Wang Y, Yao PJ, Bushlin I, Takeda A
Journal of neurochemistry   97(4) 1071-1077   May 2006   [Refereed]
Hasegawa T, Matsuzaki-Kobayashi M, Takeda A, Sugeno N, Kikuchi A, Furukawa K, Perry G, Smith MA, Itoyama Y
FEBS letters   580(8) 2147-2152   Apr 2006   [Refereed]
Takeda A, Hasegawa T, Matsuzaki-Kobayashi M, Sugeno N, Kikuchi A, Itoyama Y, Furukawa K
Journal of biomedicine & biotechnology   2006 19365   2006   [Refereed]
Nunomura A, Honda K, Takeda A, Hirai K, Zhu X, Smith MA, Perry G
Journal of biomedicine & biotechnology   2006 82323   2006   [Refereed]
Hasegawa T, Shiga Y, Narikawa K, Jin K, Fujihara K, Takeda A, Itoyama Y
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   12 820-822   Sep 2005   [Refereed]
Hasegawa T, Sugeno N, Shiga Y, Takeda A, Karibe H, Tominaga T, Itoyama Y
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   12 702-704   Aug 2005   [Refereed]
Dwyer BE, Takeda A, Zhu X, Perry G, Smith MA
Current neurovascular research   2 261-267   Jul 2005   [Refereed]
Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA
Trends in molecular medicine   11 164-169   Apr 2005   [Refereed]
Liu Q, Smith MA, Avilá J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, Ghanbari HA, Siedlak SL, Harris PL, Sayre LM, Perry G
Free radical biology & medicine   38 746-754   Mar 2005   [Refereed]
Liu Q, Lee HG, Honda K, Siedlak SL, Harris PL, Cash AD, Zhu X, Avila J, Nunomura A, Takeda A, Smith MA, Perry G
Biochimica et biophysica acta   1739 211-215   Jan 2005   [Refereed]
Takeda A, Itoyama Y, Kimpara T, Zhu X, Avila J, Dwyer BE, Perry G, Smith MA
Antioxidants & redox signaling   6 888-894   Oct 2004   [Refereed]
Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G
Neurobiology of disease   17 108-113   Oct 2004   [Refereed]
Hasegawa T, Matsuzaki M, Takeda A, Kikuchi A, Akita H, Perry G, Smith MA, Itoyama Y
Brain research   1013 51-59   Jul 2004   [Refereed]
Feng J, Misu T, Fujihara K, Misawa N, Koyanagi Y, Shiga Y, Takeda A, Sato S, Takase S, Kohnosu T, Saito H, Itoyama Y
Journal of neuroimmunology   151 189-194   Jun 2004   [Refereed]
Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA
Annals of the New York Academy of Sciences   1019 1-4   Jun 2004   [Refereed]
Kikuchi A, Takeda A, Fujihara K, Kimpara T, Shiga Y, Tanji H, Nagai M, Ichinose H, Urano F, Okamura N, Arai H, Itoyama Y
Movement disorders : official journal of the Movement Disorder Society   19 590-593   May 2004   [Refereed]
Matsuzaki M, Hasegawa T, Takeda A, Kikuchi A, Furukawa K, Kato Y, Itoyama Y
Brain research   1004 83-90   Apr 2004   [Refereed]
Hasegawa T, Matsuzaki M, Takeda A, Kikuchi A, Furukawa K, Shibahara S, Itoyama Y
Journal of neurochemistry   87(2) 470-475   Oct 2003   [Refereed]
Tateyama M, Saito N, Fujihara K, Shiga Y, Takeda A, Narikawa K, Hasegawa T, Taguchi Y, Sakuma R, Onodera Y, Ohnuma A, Tobita M, Itoyama Y
Internal medicine (Tokyo, Japan)   42(10) 1035-1038   Oct 2003   [Refereed]
Masaki T, Matsushita S, Arai H, Takeda A, Itoyama Y, Mochizuki H, Kamakura K, Ohara S, Higuchi S
Annals of neurology   54 276-277   Aug 2003   [Refereed]
Feng J, Misu T, Fujihara K, Saito H, Takahashi T, Kohnosu T, Shiga Y, Takeda A, Sato S, Takase S, Itoyama Y
Journal of neuroimmunology   141 170-173   Aug 2003   [Refereed]
Perry G, Nunomura A, Hirai K, Zhu X, Pérez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA
Free radical biology & medicine   33 1475-1479   Dec 2002   [Refereed]
Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA
Journal of neuroscience research   70 357-360   Nov 2002   [Refereed]
Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G
Neurochemistry international   40 527-531   May 2002   [Refereed]
Kikuchi A, Takeda A, Onodera H, Kimpara T, Hisanaga K, Sato N, Nunomura A, Castellani RJ, Perry G, Smith MA, Itoyama Y
Neurobiology of disease   9 244-248   Mar 2002   [Refereed]
Nunomura Akihiko, Chiba Shigeru, Kosaka Kenji, Takeda Atsushi, Castellani Rudy J, Smith Mark A, Perry George
Neuroreport   13(16) 2035-2039   2002

Misc

 
【パーキンソン病-基礎・臨床の最新情報-】 パーキンソン病の治療 パーキンソン病の非運動症状とその対応 嗅覚障害
谷口 さやか, 武田 篤
日本臨床   75(1) 119-123   Jan 2017
【基底核と小脳-その相違と連関】 症状 基底核(辺縁系皮質下核)の非運動症状
吉岡 勝, 武田 篤
Clinical Neuroscience   35(1) 90-93   Jan 2017
パーキンソン病の早期診断とdisease modifying therapyの可能性を探る研究の現在
武田 篤, 村田 美穂, 宇川 義一, 望月 秀樹
Frontiers in Parkinson Disease   9(4) 167-174   Nov 2016
【Parkinson病治療における非ドパミン系薬剤の意義】 Parkinson病治療におけるアセチルコリン系薬剤の意義
田中 洋康, 武田 篤
神経内科   85(4) 410-414   Oct 2016
【パーキンソン病の基礎と臨床の最先端】 (No.2)パーキンソン病臨床の新展開 パーキンソン病認知機能障害のトピックス
武田 篤
脳21   19(4) 374-377   Oct 2016
ドパミン補充療法の普及によりパーキンソン病(PD)の予後はめざましく改善したが、経過が長期化するとともにPDに随伴する特有の認知機能障害の存在とその発展型としての認知症(Parkinson disease dementia;PDD)の合併が問題となってきている。認知症はPDの予後に最も大きく影響することも明らかとなり、早期治療介入方法の確立は急務となっている。PDDの治療としてはコリンエステラーゼ阻害薬の有用性が確立しているがPDDの早期臨床診断はしばしば困難であり、さらにその前駆段階であ...

Books etc

 
医薬ジャーナル   May 2011   ISBN:4753224910

Conference Activities & Talks

 
パーキンソン病患者の幻覚治療の第一選択薬はDonepezilである・Yes
第4回パーキンソン病・運動障害疾患コングレス   2010   
パーキンソン病新治療ガイドラインの考え方
第28回日本神経治療学会   2010   
PET and fMRI of Olfaction in PD
6th International Congress on mental dysfunctions & other non-motor features in Parkinson’s disease   2008   
Lewy小体は善玉である・YES
第2回MDSJ   2008   
Ser129 phosphorylation of α-synuclein induces unfolded protein response mediated cell death
12th International congress of Parkinson's disease and movement disorders   2008   

Works

 
重度嗅覚障害を呈するパーキンソン病を対象としたドネペジルの予後改善効果に関する研究
2012 - 2017
運動失調症の病態解明と治療法開発に関する研究
2011 - 2014
ジストニアの診断及びと治療法の更なる推進に関する研究
2011 - 2012
スモンに関する調査研究班
2010 - 2011
運動失調症の病態解明と治療法開発に関する研究班
2010 - 2011