NIIDOME Takuro

J-GLOBAL         Last updated: Nov 8, 2018 at 11:27
 
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Name
NIIDOME Takuro
URL
http://www.chem.kumamoto-u.ac.jp/~niidome
Affiliation
Kumamoto University
Section
Unregistered
Job title
Professor
Degree
Doctor (Science)(Kyushu University)
Research funding number
20264210

Research Interests

 
 

Research Areas

 

Academic & Professional Experience

 
Dec 2012
 - 
Today
Professor, Graduate School of Science and Technology, Kumamoto University
 
Apr 2008
 - 
Nov 2012
Associate Professor, Faculty of Engineering, Kyushu University
 

Education

 
 
 - 
1994
Graduate School, Division of Natural Science, Kyushu University
 
 
 - 
1989
Faculty of Science, Kagoshima University
 

Committee Memberships

 
1994
 - 
2002
Study on structure and activity of
 
 
   
 
      amphiphilic peptide
 
1995
 - 
2002
Study on gene transfection method using
 
 
   
 
      peptide
 
1995
 - 
2002
Study on cytotoxin produced by
 

Awards & Honors

 
Jul 2011
Journal of Controlled Release Top Cited Articles 2006-2011, Elsevier
Winner: Takuro Niidome
 

Published Papers

 
Hiroaki Ichimaru, Ayaka Harada, Soichiro Yoshimoto, Yuta Miyazawa, Daigou Mizoguchi, Kaung Kyaw, Kaung Kyaw, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Takuro Niidome
Langmuir   34 10413-10418   Sep 2018
© 2018 American Chemical Society. Silver nanoparticles have antibacterial activity. However, the nanoparticles are unstable and easily form aggregates, which decreases their antibacterial activity. To improve the dispersion stability of silver nan...
Wei Xu, Kai Yagoshi, Yuki Koga, Makoto Sasaki, Takuro Niidome
Colloids and Surfaces B: Biointerfaces   163 100-106   Mar 2018   [Refereed]
© 2017 Elsevier B.V. Magnesium (Mg) alloy-based bioresorbable scaffolds (BRSs) are attracting interest as next-generation stents. However, because medical Mg alloy materials degrade relatively quickly in physiological media, surface corrosion prot...
Yoshihiro Higuchi, Takuro Niidome, Yuji Miyamoto, Yoshihiro Komohara, Tomotake Tokunou, Toru Kubota, Takahiko Horiuchi
Heart and Vessels      Jan 2018
© 2018, Springer Japan KK, part of Springer Nature. Gold nano-rods, rod-shaped gold nanoparticles, act as contrast agents for in vivo bioimaging, drug delivery vehicles and thermal converters for photothermal therapy. Pro-inflammatory cytokines pl...
Kaung Kyaw, Kaung Kyaw, Nana Motoyama, Hiroaki Ichimaru, Ayaka Harada, Shigeru Morimura, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Yuta Miyazawa, Daigou Mizoguchi, Takuro Niidome
Chemistry Letters   47 308-310   Jan 2018   [Refereed]
© 2018 The Chemical Society of Japan. A PLGA-AgNPL film was fabricated to demonstrate antibiofilm formation activity against Staphylococcus aureus. The film with a PLGA concentration of 25 mgmL -1 with 0.1%silver nanoplates showed promising (94%) ...
Akira Tsuchiya, Akira Tsuchiya, Jeong Hun Kang, Takeshi Mori, Takeshi Mori, Takeshi Mori, Yuki Naritomi, Satoshi Kushio, Takuro Niidome, Takuro Niidome, Takuro Niidome, Takuro Niidome, Katsuro Tachibana, Yoko Takahashi, Yoichi Negishi, Yusuke Oda, Ryo Suzuki, Kazuo Maruyama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Colloids and Surfaces B: Biointerfaces   160 60-64   Dec 2017   [Refereed]
© 2017 Elsevier B.V. Sonoporation is a promising method to intracellularly deliver synthetic gene carriers that have lower endocytotic uptake than viral carriers. Here, we applied sonoporation to deliver genes via polyethylene glycol (PEG)-grafted...
Kaung Kyaw, Kaung Kyaw, Hiroaki Ichimaru, Takayuki Kawagoe, Mitsuhiro Terakawa, Yuta Miyazawa, Daigou Mizoguchi, Masayuki Tsushida, Takuro Niidome
Nanoscale   9 16101-16105   Nov 2017   [Refereed]
© 2017 The Royal Society of Chemistry. Gold-coated silver nanoplates, when subjected to pulsed laser irradiation, changed their shape from triangular to spherical, accompanied by a shift of their extinction spectra. The simple single crystal struc...
Aung Thu Haine, Aung Thu Haine, Yuki Koga, Yuta Hashimoto, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Hidetoshi Arima, Takuro Niidome
European Journal of Pharmaceutics and Biopharmaceutics   119 91-95   Oct 2017
© 2017 Elsevier B.V. Transdermal protein delivery is a useful and attractive method for protein therapy and dermal vaccination. However, this delivery method is restricted by the low permeability of the stratum corneum. The purpose of this study w...
Yoshihiro Komohara, Ryuta Kawauchi, Erika Makiyama, Kazuki Mikami, Hasita Horlad, Yukio Fujiwara, Tetsuya Kida, Motohiro Takeya, Takuro Niidome
Experimental and Therapeutic Medicine   14 1640-1646   Aug 2017
© 2017, Spandidos Publications. All rights reserved. Previous studies have indicated pro-tumor functions of macrophages in tumor progression in different types of malignant tumors. The detailed mechanisms of cell-cell interaction between macrophag...
Aung Thu Haine, Aung Thu Haine, Yuji Miyamoto, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Hidetoshi Arima, Takuro Niidome
Journal of Biomaterials Science, Polymer Edition   28 1-11   Jul 2017   [Refereed]
© 2017 Informa UK Limited, trading as Taylor & Francis Group Transdermal protein delivery is a powerful and attractive method for protein therapy and dermal vaccination compared with other administrations. However, this delivery method is restri...
Ma C, Horlad H, Pan C, Yano H, Ohnishi K, Fujiwara Y, Matsuoka M, Lee A, Niidome T, Yamanaka R, Takeya M, Komohara Y
Journal of clinical and experimental hematopathology : JCEH   57(1) 21-25   Jul 2017   [Refereed]
Aung Thu Haine, Aung Thu Haine, Takuro Niidome
Chemical and Pharmaceutical Bulletin   65 625-628   Jan 2017   [Refereed]
© 2017 The Pharmaceutical Society of Japan. Gold nanorods are promising metals in several biomedical applications such as bioimaging, thermal therapy, and drug delivery. Gold nanorods have strong absorption bands in near-infrared (NIR) light regio...
Misato Takizaki, Shun ichiro Muranaka, Aung Thu Haine, Aung Thu Haine, Shigenori Tokunaga, Shigeru Morimura, Takuro Niidome
Chemistry Letters   46 1158-1160   Jan 2017   [Refereed]
© 2017 The Chemical Society of Japan Gene transfection can be enhanced by heat treatment. In this study, we examined the enhancement mechanism. Heat treatment before transfection showed higher enhancement than during or after the transfection. The...
Xiangyong Zeng, Takahiro Hosono, Midori Matsunaga, Hiroto Ohta, Takuro Niidome, Jun Shimada, Shigeru Morimura
Journal of Water and Environment Technology   15 152-162   Jan 2017   [Refereed]
© 2017 Japan Society on Water Environment. The hydrogeological properties of groundwater and behavior of nitrate attenuation in the nitratepolluted alluvial aquifer, Miyakonojo Basin have been investigated in previous studies, but little knowledge...
Kaung Kyaw, Kaung Kyaw, Ayaka Harada, Hiroaki Ichimaru, Takayuki Kawagoe, Kinnosuke Yahiro, Shigeru Morimura, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Takuro Niidome
Chemistry Letters   46 594-596   Jan 2017   [Refereed]
© 2017 The Chemical Society of Japan. Silver nanoparticles are known to have antimicrobial activity. In this study, we investigated the effect of silver nanoparticles on biofilms of different human pathogenic bacteria. Silver nanoparticles at conc...
Masayuki Nakano, Masayuki Nakano, Kinnosuke Yahiro, Eiki Yamasaki, Hisao Kurazono, Junko Akada, Yoshio Yamaoka, Yoshio Yamaoka, Takuro Niidome, Masanori Hatakeyama, Hidekazu Suzuki, Taro Yamamoto, Joel Moss, Hajime Isomoto, Toshiya Hirayama
DMM Disease Models and Mechanisms   9(12) 1473-1481   Dec 2016   [Refereed]
© 2016. Published by The Company of Biologists Ltd | Disease Models & Mechanisms. Helicobacter pylori, a major cause of gastroduodenal diseases, produces vacuolating cytotoxin (VacA) and cytotoxin-associated gene A (CagA), which seem to be invol...
Xiangyong Zeng, Takahiro Hosono, Hiroto Ohta, Takuro Niidome, Jun Shimada, Shigeru Morimura
International Biodeterioration and Biodegradation   114 109   Oct 2016   [Refereed]
© 2016 Elsevier Ltd.A denitrification hotspot was detected in Kumamoto groundwater in a previous study, little information is concerned with the microbial community profile including denitrifier. Seven samples from inside and outside of the hotspo...
Takuro Niidome
Kobunshi   65 420-422   Aug 2016
The control technique of drug delivery systems by external stimuli is an important key for improving its efficiency and reducing undesirable side effects of the drug. Near-infrared light, alternating magnetic field and ultrasound, etc. are used as...
Takuro Niidome
Drug Delivery System   31 477-479   Jan 2016   [Refereed][Invited]
Youhei Takebe, Misato Takizaki, Hiroko Tanaka, Hiroto Ohta, Takuro Niidome, Shigeru Morimura
Food Science and Technology Research   22 673-678   Jan 2016   [Refereed]
Copyright © 2016, Japanese Society for Food Science and Technology. Tofu-misozuke is a traditional fermented food in Japan, and contains biogenic amines that function as neurotransmitters, but are toxic when consumed at high levels. Analysis of th...
Yasuro Niidome, Aung Thu Haine, Aung Thu Haine, Takuro Niidome
Chemistry Letters   45(5) 498   Jan 2016   [Refereed]
© 2016 The Chemical Society of Japan.Among the several types of nanoparticles in existence, anisotropic gold-based nanoparticles demonstrate special advantages because of their unique properties. Gold nanoparticles can be prepared and modified wit...

Misc

 
Masanori Fujii, Naotoshi Nakashima, Naotoshi Nakashima, Naotoshi Nakashima, Takuro Niidome, Yasuro Niidome, Yasuro Niidome
Chemistry Letters   43 131-133   Jan 2014
Laser-induced desorption and ionization (LDI) of gold ions (Aun +: n = 13) were observed from gold nanorods in a liver tissue section (thickness: 10 -m). Larger amounts of gold nanorods produced stronger mass signals. Organic molecules in the tiss...
Yuki Otsubo, Hiromu Ikeda, Junpei Kamimoto, Takuro Niidome, Takuro Niidome, Takeshi Mori, Takeshi Mori, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Chemistry Letters   43 658-660   Jan 2014
A rapid and quantitative measurement of protein kinase activity based on MALDI-TOF-MS was developed. Here, biotinylated substrate peptides with stable isotope labeling were used to enable the rapid and specific enrichment of the peptides. Protein ...
Masako Sakai, Hiroto Ohta, Takuro Niidome, Shigeru Morimura
Food Science and Technology Research   20 693-698   Jan 2014
Changes in microbial community composition of takana produced by a conventional fermenatation method with 6% (w/w) NaCl were analyzed. Harvested takana leaves were pickled with 6% (w/w) NaCl in Aso city, transported to our laboratory in Kumamoto c...
Takuro Niidome
Kobunshi   63 33-34   Jan 2014
Development of drug delivery techniques is an important challenge to achieve successful chemotherapy without side effect In the past three decades, lots of delivery techniques mediated by functional liposomes, polymers and so on have been reported...
Takuro Niidome, Nobukatsu Chijiiwa, Toshihide Yamasaki, Ken Ichi Yamada, Takeshi Mori, Takeshi Mori, Tatsuya Naganuma, Hideo Utsumi, Kazuhiro Ichikawa, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Chemistry Letters   43 999-1001   Jan 2014
Dendritic poly(L-lysine) polymers were modified with stable nitroxyl radicals through the substrate peptides of a protease specifically expressed in tumors. Cleavage of the peptides by the protease affected the Overhauser-enhanced MRI (OMRI) signa...
Yasuyuki Akiyama, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Takuro Niidome
Journal of Biomaterials Science, Polymer Edition   24 2071-2080   Dec 2013
Gold nanorods modified with polyethylene glycol (PEG) chains via Au-S bonds form aggregates, and their absorption spectra broaden in tumor tissues. In contrast, the gold nanorods modified here via the crosslinking of PEG chains on the silica shell...
H. Ikeda, J. Kamimoto, T. Yamamoto, A. Hata, Y. Otsubo, T. Niidome, T. Niidome, M. Fukushima, T. Mori, T. Mori, Y. Katayama, Y. Katayama
Current Medicinal Chemistry   20 4419-4425   Nov 2013
Phosphatidylcholine-polymer-coated plastic slides were utilized for the fabrication of peptide microarrays for cellular kinome analysis. According to the non-fou ling features of the surface, the signal-to-noise ratio of the detection of phosphory...
Yuta Nakamura, Chan Woo Kim, Akira Tsuchiya, Satoshi Kushio, Takanobu Nobori, Kai Li, Eun Kyung Lee, Guo Xi Zhao, Daiki Funamoto, Takuro Niidome, Takeshi Mori, Takeshi Mori, Takeshi Mori, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Journal of Biomaterials Science, Polymer Edition   24 1858-1868   Nov 2013
We examined in vitro performance of the branched polyethylenimine (bPEI)-based gene carriers which respond to cancer-specific activation of protein kinase Cα (PKCα) to express plasmid DNA. The carriers were synthesized straightforward by using ami...
Satoshi Kushio, Akira Tsuchiya, Yuta Nakamura, Takanobu Nobori, Chan Woo Kim, Guo Xi Zhao, Taiki Funamoto, Eun Kyung Lee, Takuro Niidome, Takuro Niidome, Takeshi Mori, Takeshi Mori, Yoshiki Katayama, Yoshiki Katayama
Biomedical Engineering - Applications, Basis and Communications   25    Oct 2013
Protein kinase (PK)-responsive gene carriers modified with polyethylene glycol (PEG) chains using an acid-labile linker were developed. These carriers were obtained by modifying the PEG chains and substrate peptides for the PKs (PKA or PKCα) on th...
Jeong Hun Kang, Jeong Hun Kang, Takeshi Mori, Takeshi Mori, Hirotaro Kitazaki, Takuro Niidome, Takuro Niidome, Koichi Takayama, Yoichi Nakanishi, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Cancer Biomarkers   13 99-103   Jul 2013
BACKGROUND: Several serum biomarkers such as antigens, soluble proteins, metabolites, and genes have been identified for the diagnosis of cancers and for monitoring the recurrence after cancer treatment. METHODS: In the present study, a protein ki...
Yuki Sakamura, Moemi Yoshiura, Hengmin Tang, Takeshi Mori, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Takuro Niidome
Chemistry Letters   42 767-768   Jul 2013
A plasmid DNA and gold nanorods were directly injected to tumor in mice, and the tumor was heated to 3942 °C through the photothermal effect of the gold nanorods. The heat treatment enhanced transgene expression from the plasmid DNA in the tumor a...
Shujiro Shiosaki, Takanobu Nobori, Takeshi Mori, Takeshi Mori, Riki Toita, Yuta Nakamura, Chan Woo Kim, Tatsuhiro Yamamoto, Takuro Niidome, Takuro Niidome, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Chemical Communications   49 5592-5594   Jun 2013
A novel protein kinase assay was developed, based on FRET between QDs and fluorescently-labeled substrate peptides. The negatively charged QDs recognize the change in net charge of the peptide upon phosphorylation. Despite its simple mechanism, th...
Chan Woo Kim, Riki Toita, Jeong Hun Kang, Kai Li, Eun Kyung Lee, Guo Xi Zhao, Daiki Funamoto, Takanobu Nobori, Yuta Nakamura, Takeshi Mori, Takeshi Mori, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Journal of Controlled Release   170 469-476   Jan 2013
Here, we developed a new gene carrier, comprising a linear polyethylenimine (LPEI) grafted with a hydro-phobically modified cationic peptide containing a long alkyl chain, for use in cancer-specific gene delivery. The cationic peptide is a substra...
Hengmin Tang, Hiroaki Kobayashi, Yasuro Niidome, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Takuro Niidome
Journal of Controlled Release   171 178-183   Jan 2013
Transdermal delivery is a useful and attractive method for drug delivery, even though the stratum corneum is a major barrier of protein translocation into the skin. To achieve protein delivery through the stratum corneum, we first cast gold nanoro...
Dakrong Pissuwan, Takuro Niidome, Takuro Niidome, Takuro Niidome
ACS Symposium Series   1113 69-80   Nov 2012
The transdermal delivery is an attractive approach for the delivery of therapeutic molecules, which provides a lot of benefits to patients. However, the delivery of high-molecular-weight drugs (especially hydrophilic agents) is problematic because...
Takuro Niidome, Yasuro Niidome
Kobunshi   61 537-538   Aug 2012
Gold nanoparticles that have an absorption band at near infrared region have attracted much attention. Since near infrared light can penetrate deeply into tissues, they can beused not only as heating device for hyperthermia but also as a control d...
Hiromitsu Fukushima, Shuji Yamashita, Takeshi Mori, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama, Takuro Niidome, Takuro Niidome, Takuro Niidome
Chemistry Letters   41 711-712   Jul 2012
Gold nanorods were modified with two types of doublestranded DNAs (dsDNA) with different melting temperatures. Irradiated by near-infrared laser light, the modified gold nanorods were heated, and single-stranded DNAs were released faster from the ...
Akira Tsuchiya, Jeong Hun Kang, Daisuke Asai, Takeshi Mori, Takeshi Mori, Takuro Niidome, Takuro Niidome, Takuro Niidome, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Journal of Controlled Release   155 40-46   Oct 2011
Recently, we have proposed a new system of gene regulation called 'drug or gene delivery system responding to cellular signals' (D-RECS). In this system, transgene expression is activated in response to intracellular target protein kinases or prot...
Jeong Hun Kang, Jun Oishi, Jun Oishi, Jong Hwan Kim, Moeko Ijuin, Moeko Ijuin, Riki Toita, Riki Toita, Byungdug Jun, Daisuke Asai, Takeshi Mori, Takeshi Mori, Takuro Niidome, Takuro Niidome, Takuro Niidome, Katsuyuki Tanizawa, Shun'ichi Kuroda, Yoshiki Katayama, Yoshiki Katayama, Yoshiki Katayama
Nanomedicine: Nanotechnology, Biology, and Medicine   7 514   Aug 2011

Books etc

 
多比良 和誠, 片岡 一則, 新留 琢郎
Springer   2005   ISBN:4431251227

Conference Activities & Talks

 
Control of Antibacterial Activity of Gold-coated Silver Nanoplates by Laser Irradiation
Kaung Kyaw, Hiroaki Ichimaru, Mitsuhiro Terakawa, Yuta Miyazawa, Daigou Mizoguchi, Masayuki Tsushida, Takuro Niidome
2017 MRS Fall Meeting & Exhibit   26 Nov 2017   
Control of antibacterial activity of silver nanoparticles by light irradiation [Invited]
Takuro Niidome
1st Minisymposium on Material Biology   16 Oct 2017   
Silver Nanoparticles as Antibiofilm Formation Agents [Invited]
Kaung Kyaw, Haroaki Ichimaru, Ayaka Harada, Nana Motoyama, Takuro Niidome
27 Sep 2017   
Transdermal Protein delivery using hydrogel patch system carrying ovalbumin and its epitope peptide
Aung Thu Haine, Yuji Miyamoto, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima and Takuro Niidome
Biomaterial International 2017   20 Aug 2017   
Corrosion resistance and sirolimus release controlled of bioresorbable scaffold
Wei Xu, Yuuki Koga, Makoto sasaki, Takuro Niidome
Biomaterial International 2017   20 Aug 2017   
Anti-biofilm Activity of Silver Nanoparticles
Kaung Kyaw, Ayaka Harada, Hiroaki Ichimaru, Takayuki Kawagoe, Kinnosuke Yahiro, Shigeru Morimura, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Takuro Niidome
Biomaterial International 2017   20 Aug 2017   
Double-layer polymer coating for bioabsorbable and drug eluting coronary stent
Wei Xu
44th Annual Meeting & Exposition of the Controlled Release Society   16 Jul 2017   
Gold-layers Coating of Silver Nanoplates for Enhanced Dispersion Stability and Antibacterial Activities
Takuro Niidome
44th Annual Meeting & Exposition of the Controlled Release Society   16 Jul 2017   
Transdermal Protein Delivery by Using Polysaccharide Hydrogel coated with gold nanords
Aung Thu Haine
International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)   9 Mar 2017   
Drug Delivery System Controlled by Near Infrared Light
NIIDOME Takuro
Kumamoto Symposium on Therapeutic/Diagnosis Techniques and Medical Devices   15 Feb 2017   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2007 - 2009    Investigator(s): Takuro NIIDOME
Gold nanorods adsorb infrared light, then, the light energy is converted to heat. In this study, we optimized condition of PEG-modification of the gold nanorods to make them circulate blood stably and show EPR effect. Furthermore, we succeeded in ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2005 - 2008    Investigator(s): Naotoshi NAKASHIMA
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2006 - 2007    Investigator(s): Toshitaka OOHASHI
1. Coating method for siRNA on stent was examined. As one of the model cases, Glycosminoglycans were bound on the titanium oxide surface. A basic PTD peptide binding to GAGs was determined by QCM method. Further, the uptake of the peptide into the...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2003 - 2004    Investigator(s): Yoshiki KATAYAMA
In this research, we investigated a design and characterization of nano-drug capsule and gene delivery system that respond to intracellular protein kinse A (PKA) or caspase-3. Then using their results, another gene carrier responding to intracellu...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2002 - 2003    Investigator(s): Haruhiko AOYAGI
The development of a non-viral gene delivery system into cells is an important key to realize the safe delivery of therapeutic genes without the side effects often pointed out for viral vectors. We have shown that dendritic poly (L-lysine) of the ...
Study on functional gene delivery system into cells
Grant-in-Aid for Scientific Research
Project Year: 1996   
Study on Structure and function of amphiphilic pepticle
Grant-in-Aid for Scientific Research
Project Year: 1993   
Bioimaging and photothermal therapy using gold nanorods
Grant-in-Aid for Scientific Research
Project Year: 2004