2008年2月
Availability of cardio-ankle vascular index (CAVI) as a screening tool for atherosclerosis
CIRCULATION JOURNAL
- 巻
- 72
- 号
- 2
- 開始ページ
- 304
- 終了ページ
- 308
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1253/circj.72.304
- 出版者・発行元
- JAPANESE CIRCULATION SOC
Background A novel index, the cardio-ankle vascular index (CAVI), which reflects the stiffness of the aorta, femoral artery, and tibial artery, was recently developed by measuring brachial-ankle pulse wave velocity and blood pressure.
Methods and Results In the present study 1,014 Japanese adults from the general population were screened to clarify the correlation between CAVI and other existing markers related to atherosclerosis, including carotid intima-media thickness (CIMT) and homocysteine (HCY). CAVI was strongly associated with age in both men and women. After adjustment for age and sex, CAVI was correlated with systolic and diastolic blood pressures. In addition, CAVI was significantly correlated with total cholesterol hemoglobin A1c and total HCY, as well as CIMT.
Conclusion CAVI is an appropriate screening tool for atherosclerosis, but further studies are needed to establish a convenient and effective screening system using it.
Methods and Results In the present study 1,014 Japanese adults from the general population were screened to clarify the correlation between CAVI and other existing markers related to atherosclerosis, including carotid intima-media thickness (CIMT) and homocysteine (HCY). CAVI was strongly associated with age in both men and women. After adjustment for age and sex, CAVI was correlated with systolic and diastolic blood pressures. In addition, CAVI was significantly correlated with total cholesterol hemoglobin A1c and total HCY, as well as CIMT.
Conclusion CAVI is an appropriate screening tool for atherosclerosis, but further studies are needed to establish a convenient and effective screening system using it.
- リンク情報
-
- DOI
- https://doi.org/10.1253/circj.72.304
- CiNii Articles
- http://ci.nii.ac.jp/naid/110006571061
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/18219171
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000252731900023&DestApp=WOS_CPL
- ID情報
-
- DOI : 10.1253/circj.72.304
- ISSN : 1346-9843
- CiNii Articles ID : 110006571061
- PubMed ID : 18219171
- Web of Science ID : WOS:000252731900023