NAKADA, Masahisa

J-GLOBAL         Last updated: Nov 28, 2019 at 02:51
NAKADA, Masahisa
Waseda University
Faculty of Science and Engineering School of Advanced Science and Engineering
Job title
Research funding number

Research Areas



Faculty of Pharmaceutical Science, University of Tokyo
Graduate School, Division of Pharmaceutical Sciences, University of Tokyo

Published Papers

Fujii, Tomohiro; Oki, Yuta; Nakada, Masahisa
Tetrahedron Letters   59(10) 882-886   Mar 2018
© 2018 Elsevier Ltd The Liebeskind-Srogl coupling/intramolecular Diels-Alder (IMDA) reaction cascade that stereoselectively affords a tricarbocyclic compound with a trans–trans-cis fused ring system including an all-carbon quaternary stereogenic c...
Oki, Yuta; Nakada, Masahisa
Tetrahedron Letters   59(10) 922-925   Mar 2018
© 2018 Elsevier Ltd The Au(I)-catalyzed ene-yne cycloisomerization pathway which is highly dependent on the substrate structures is described. The steric and electronic effects of substrate substituents could be important factors inducing the form...
Oki, Yuta; Nakada, Masahisa
Tetrahedron Letters   59(10) 926-929   Mar 2018
© 2018 Elsevier Ltd Compounds that undergo Au(I)-catalyzed cycloisomerizations affording tetracyclic products that can be converted into compounds with the skeleton of bruceantin are described. The Au(I)-catalyzed cycloisomerizations reported here...
Saito, Emi; Matsumoto, Yuri; Nakamura, Akihiko; Namera, Yuki; Nakada, Masahisa
Organic Letters   20(3) 692-695   Feb 2018
© 2018 American Chemical Society. The preparation and reactions of ortho-benzoquinone monohemiaminals are described. The oxidative dearomatization of phenols bearing amino alcohol groups induced N-cyclization to afford ortho-benzoquinone monohemia...
Inoue, Saori; Nagatani, Kotaro; Tezuka, Haruka; Hoshino, Yunosuke; Nakada, Masahisa
Synlett   28(9) 1065-1070   Jun 2017
© Georg Thieme Verlag Stuttgart.New York. The catalytic asymmetric intramolecular cyclopropanation (CAIMCP) of α-diazo-α-silyl acetates to form oxabicyclo[3.2.1]hexane, which proceeds with high yields and enantioselectivities, is described. The ma...

Conference Activities & Talks

Studies on Convergent and Enantioselective Total Synthesis of Taxol
9th Annual Florida Heterocyclic and Synthetic IUPAC-Sponsored Conference   Mar 2008   
Biomimetic Total Synthesis of (−)-Erinacine E
9th Annual Florida Heterocyclic and Synthetic IUPAC-Sponsored Conference   Mar 2008   
Studies on Convergent and Enantioselective Total Synthesis of Taxol
Mar 2008   
Enantioselective Total Synthesis of (-)-Erinacine E
Mar 2008   
Synthetic studies on (+)-bucidarasin C
Mar 2008   

Research Grants & Projects

Efficient Synthesis of Important Bioactive Medium-Size Polycyclic Natural Products
Project Year: Jun 2015 - Mar 2020
Research on Asymmetric Catalysis Based on Design and Synthesis of New Chiral Pincer-Type NHC Ligand
Project Year: Apr 2014 - Mar 2016
We have established a synthetic method for the bisoxazoline-NHC-Ag(I) complex via concomitant formation of oxazolines and NHC using silver oxide, and the bisoxazoline-NHC-Ag(I) complex were converted to the corresponding pincer-type NHC-metal comp...
Catalytic Asymmetric Reactions of Alkenes Activated by Two Electron-Withdrawing Groups and Their Applications to Efficient Enantioselective Total Syntheses
Project Year: Apr 2013 - Mar 2016
A synthetic method of alpha-alkylidene-beta-oxo imides and their catalytic asymmetric reactions ([4+2] and [2+2]cycloadditions, Mukaiyama-Michael reaction, Hosomi-Sakurai-Michael reaction, and Friedel-Crafts reaction) have been successfully develo...
Research on the design and synthesis of chiral NHC pincer ligands and their utility for asymmetric catalysis
Project Year: Apr 2011 - Mar 2013
A new chiral N-heterocyclic carbene (NHC) pincer-type ligand was synthesized. Its cationic platinum complex catalyzed an enantioselective cycloisomerization of a 1,5-ene-yne. A new preparation method of imidazolinium salts from the corresponding t...
Synthetic Studies on Bioactive Natural Products utilizing Integrated
Project Year: Apr 2009 - Mar 2014
We have studied the total synthesis of bioactive natural products via integrated reactions developed by focusing our attention on reactive intermediates. (1)Anion: Total syntheses of (-)-scabronines G, A, D, and (-)-episcabronine A have been achie...


2004-196710 : 配位子及び不斉触媒
中田 雅久