2015年3月
A highly stereoselective intramolecular Diels-Alder reaction for construction of the AB ring moiety of bruceantin
TETRAHEDRON LETTERS
- ,
- ,
- 巻
- 56
- 号
- 10
- 開始ページ
- 1247
- 終了ページ
- 1251
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.tetlet.2015.01.139
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
A highly stereoselective intramolecular Diels Alder (IMDA) reaction for the construction of the AB ring moiety of bruceantin is described. The product of the IMDA reaction comprises a trans-AB ring junction and stereotetrad including an all carbon quaternary stereogenic center, wherein three stereogenic centers correspond to those of bruceantin. Functional groups embedded in the product are suitable for a variety of transformations. Hence, this IMDA product could be a useful intermediate for the enantioselective total synthesis of not only bruceantin, but also other bioactive compounds. (C) 2015 Elsevier Ltd. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/j.tetlet.2015.01.139
- ISSN : 0040-4039
- Web of Science ID : WOS:000350528300018