Dec 10, 2004
Direct evidence for expression of dopamine receptors in astrocytes from basal ganglia
Brain Research
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- Volume
- 1029
- Number
- 1
- First page
- 120
- Last page
- 123
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1016/j.brainres.2004.09.014
Expression of dopamine receptors (DA-Rs) in astrocytes was examined in vitro and in vivo using primary cultured astrocytes and brain slices from rat basal ganglia. Astrocytes from basal ganglia expressed DA D1-, D3-, D4- and D5-receptors and D4-mediated signal transduction in response to DA, suggesting possible involvement of astrocytes in the pharmacological action of atypical antipsychotic drugs and in DA response in some neurological diseases. © 2004 Elsevier B.V. All rights reserved.
- Link information
- ID information
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- DOI : 10.1016/j.brainres.2004.09.014
- ISSN : 0006-8993
- Pubmed ID : 15533323
- SCOPUS ID : 7744242098
- Web of Science ID : WOS:000225481700014