2014年10月
Methylphenidate improves learning impairments and hyperthermia-induced seizures caused by an Scn1a mutation.
Epilepsia
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- 巻
- 55
- 号
- 10
- 開始ページ
- 1558
- 終了ページ
- 1567
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1111/epi.12750
- 出版者・発行元
- Wiley Periodicals, Inc.
Developmental disorders including cognitive deficit, hyperkinetic disorder, and autistic behaviors are frequently comorbid in epileptic patients with SCN1A mutations. However, the mechanisms underlying these developmental disorders are poorly understood and treatments are currently unavailable. Using a rodent model with an Scn1a mutation, we aimed to elucidate the pathophysiologic basis and potential therapeutic treatments for developmental disorders stemming from Scn1a mutations.
- リンク情報
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- DOI
- https://doi.org/10.1111/epi.12750
- CiNii Articles
- http://ci.nii.ac.jp/naid/120005522498
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000344173800012&DestApp=WOS_CPL
- URL
- https://onlinelibrary.wiley.com/doi/pdf/10.1111/epi.12750
- URL
- https://onlinelibrary.wiley.com/doi/full-xml/10.1111/epi.12750
- URL
- http://onlinelibrary.wiley.com/wol1/doi/10.1111/epi.12750/fullpdf
- ID情報
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- DOI : 10.1111/epi.12750
- ISSN : 0013-9580
- eISSN : 1528-1167
- CiNii Articles ID : 120005522498
- Web of Science ID : WOS:000344173800012