Tahara Hidetoshi

J-GLOBAL         Last updated: Sep 11, 2019 at 02:48
Tahara Hidetoshi
Hiroshima University
Job title
Research funding number


My research fields are Telomere, microRNA and exosome in aging and cancer.

Published Papers

microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer
Obayashi, Mariko; Yoshida, Maki; Tsunematsu, Takaaki; Ogawa, Ikuko; Sasahira, Tomonori; Kuniyasu, Hiroki; Imoto, Issei; Abiko, Yoshimitsu; Xu, Dan; Fukunaga, Saori; Tahara, Hidetoshi; Kudo, Yasusei; Nagao, Toshitaka; Takata, Takashi
ONCOTARGET   7(7) 8223-8239   Feb 2016   [Refereed]
Head and neck squamous cell carcinoma (HNSCC) has a high capacity for invasion. To identify microRNAs (miRNAs) that regulate HNSCC invasion, we compared miRNA expression profiles between a parent HNSCC cell line and a highly invasive clone. The mi...
Hosoi, Toru; Nakatsu, Kanako; Shimamoto, Akira; Tahara, Hidetoshi; Ozawa, Koichiro
NEUROSCIENCE LETTERS   629 241-244   Aug 2016   [Refereed]
Endoplasmic reticulum (ER) stress is implicated in several diseases, such as cancer and neurodegenerative diseases. In the present study, we investigated the possible involvement of telomerase in ER stress-induced cell death. ER stress-induced cel...
Mateescu, Bogdan; Kowal, Emma J. K.; van Balkom, Bas W. M.; Bartel, Sabine; Bhattacharyya, Suvendra N.; Buzas, Edit I.; Buck, Amy H.; de Candia, Paola; Chow, Franklin W. N.; Das, Saumya; Driedonks, Tom A. P.; Fernandez-Messina, Lola; Haderk, Franziska; Hill, Andrew F.; Jones, Jennifer C.; Van Keuren-Jensen, Kendall R.; Lai, Charles P.; Laesser, Cecilia; di Liegro, Italia; Lunavat, Taral R.; Lorenowicz, Magdalena J.; Maas, Sybren L. N.; Maeger, Imre; Mittelbrunn, Maria; Momma, Stefan; Mukherjee, Kamalika; Nawaz, Muhammed; Pegtel, D. Michiel; Pfaffl, Michael W.; Schiffelers, Raymond M.; Tahara, Hidetoshi; Thery, Clotilde; Tosar, Juan Pablo; Wauben, Marca H. M.; Witwer, Kenneth W.; Nolte-'t Hoen, Esther N. M.
The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has been demonstrated in a multitude of different in vitro cell systems and in a variety of body fluids. RNA-containing EV are in the limelight for their capac...
Shimamoto, Akira; Yokote, Koutaro; Tahara, Hidetoshi
FRONTIERS IN GENETICS   6    Jan 2015   [Refereed]
Werner syndrome (WS) is a rare human autosomal recessive premature aging disorder characterized by early onset of aging-associated diseases, chromosomal instability, and cancer predisposition. The function of the DNA helicase encoded by WRN, the g...
Reiner, Agnes T.; Witwer, Kenneth W.; van Balkom, Bas W. M.; de Beer, Joel; Brodie, Chaya; Corteling, Randolph L.; Gabrielsson, Susanne; Gimona, Mario; Ibrahim, Ahmed G.; de Kleijn, Dominique; Lai, Charles P.; Lotvall, Jan; del Portillo, Hernando A.; Reischl, Ilona G.; Riazifar, Milad; Salomon, Carlos; Tahara, Hidetoshi; Toh, Wei Seong; Wauben, Marca H. M.; Yang, Vicky K.; Yang, Yijun; Yeo, Ronne Wee Yeh; Yin, Hang; Giebel, Bernd; Rohde, Eva; Lim, Sai Kiang
STEM CELLS TRANSLATIONAL MEDICINE   6(8)    Aug 2017   [Refereed]
Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell-related approaches, has underlined the need for standardization and coordination of development efforts. Memb...

Conference Activities & Talks

Extracellular RNA is promising biomarker for eary detection of cancers
Hidetoshi Tahara
ISEV2017   19 May 2017   
MicroRNA and exosome in Aging [Invited]
Hidetoshi Tahara
15 Jun 2017   
"An in vitro model for cancer stem cell dormancy and recurrence using tetinducible reprogramming system" [Invited]
1 Jul 2017   
Screening of senescence-inducible microRNAs for cancer therapy
1 Jul 2017   
miRNA in aging and cancer [Invited]
28 Aug 2017