MISC

2001年11月

Association of plasma adrenomedullin with carotid atherosclerosis in chronic ischemic stroke

PEPTIDES
  • K Shinomiya
  • ,
  • K Ohmori
  • ,
  • H Ohyama
  • ,
  • N Hosomi
  • ,
  • T Takahashi
  • ,
  • K Osaka
  • ,
  • M Kohno

22
11
開始ページ
1873
終了ページ
1880
記述言語
英語
掲載種別
DOI
10.1016/S0196-9781(01)00507-1
出版者・発行元
ELSEVIER SCIENCE INC

Adrenomedullin is a potent vasodilator peptide exerting anti-atherosclerotic actions in vitro. We investigated the impact of the severity of atherosclerosis on plasma mature-adrenomedullin (m-AM) levels in 38 patients with chronic ischemic stroke. The variables of carotid artery atherosclerosis assessed using ultrasound measurement, blood pressure, and risk factors were related to m-AM levels. Severe atherosclerosis was associated with a further elevation of the increased m-AM level in patients with high systolic blood pressure. Even in patients with fewer risk factors, the presence of severe atherosclerosis was associated with an increased m-AM level. Thus, atherosclerosis elevates m-AM independent of the blood pressure level or presence of risk factors. (C) 2001 Elsevier Science Inc. All rights reserved.

Web of Science ® 被引用回数 : 19

リンク情報
DOI
https://doi.org/10.1016/S0196-9781(01)00507-1
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000172999500022&DestApp=WOS_CPL

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