NAKANE Akio

J-GLOBAL         Last updated: Apr 28, 2015 at 09:57
 
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Name
NAKANE Akio
Affiliation
Hirosaki University
Section
School of Medicine, Medicine, Department of Bacteriology
Degree
(BLANK)(Hokkaido University), (BLANK)(Hokkaido University)

Research Areas

 
 

Academic & Professional Experience

 
1980
 - 
1981
University of Wisconsin-Madison,
 
 
   
 
Research Associate
 
1983
 - 
1984
Hokkaido University, Research Assistant
 
1984
 - 
1989
Hokkaido University, Lecturer
 
1989
 - 
1994
Hokkaido University, Assistant Professor
 

Education

 
 
 - 
1980
Graduate School, Division of Medicine, Hokkaido University
 
 
 - 
1974
Faculty of Agriculture, Hokkaido University
 

Awards & Honors

 
Mar 2014
Host responses to bacterial infections, Asakawa Award, Japanese Society for Bacteriology
 

Published Papers

 
Narita K, Hu DL, Asano K, Nakane A
Pathogens and disease   73(4)    Jun 2015   [Refereed]
Sato'o Y, Omoe K, Naito I, Ono HK, Nakane A, Sugai M, Yamagishi N, Hu DL
Journal of clinical microbiology   52(7) 2637-2640   Jul 2014   [Refereed]
Hu DL, Nakane A
European journal of pharmacology   722 95-107   Jan 2014   [Refereed]
Yoshimura S, Asano K, Nakane A
BioMed research international   2014 406453   2014   [Refereed]
Nakane A
Nihon saikingaku zasshi. Japanese journal of bacteriology   69(3) 479-489   2014   [Refereed]

Misc

 
Host resistance to an intragastric infection with ┣DBListeria(/)-┫DB ┣DBmonocytogenes(/)-┫DB in mice depends on cellular immunity and intestinal Bacterial flora(共著)
Infection and Immunity   62(8) 3080-3085   1994
Endogenous gamma interferon, tumor necrosis factor, and interleukin-6 in ┣DBStaphylococcus(/)-┫DB ┣DBaureus(/)-┫DB infection in mice(共著)
Infection and Immunity   63(4) 1165-1172   1995
Sequential involvement of NK cells and CD8+ T cells in granuloma formation of ┣DBRhodococcus(/)-┫DB ┣DBaurantiacus(/)-┫DB-infected mice(共著)
Microbiology and Immunology   39(7) 499-507   1995

Works

 
Development of vaccines of the next generetion ageinst Staphylococcus aureus
2001

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2008 - 2011    Investigator(s): Akio NAKANE
We investigated roles of staphylococcal enterotoxin family molecules in infection, emesis and diarrhea.(1) TSST-1 played an important role in pathogenesis of Staphylococcus aureus infectio(2) Among SEA, SEC and TSST-1, SEA and SEC showed emesis-in...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2006 - 2007    Investigator(s): Akio NAKANE
Staphylococcal enterotoxin A (SEA) is an extracellular protein produced by Staphylococcus aureus. SEA shows emetic activity and superantigenic activity. The mechanism of emetic activity of SEA has been little known. In the present study, we demons...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2004 - 2005    Investigator(s): Akio NAKANE
Leptin is an adipocyte-derived hormone that regulates a number of physiological functions, including energy homeostasis and immune function. We investigated a role of leptin in Listeria monocytogenes infection using leptin receptor-deficient db/db...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2001 - 2002    Investigator(s): Akio NAKANE
The host defense mechanism against bacterial infections through catecholamine receptors was investigated. Furthermore, the role of macrophage migration inhibitory factor (MIF), which is known to mediate the crosstalk between immune system and nerv...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1998 - 2000    Investigator(s): Akio NAKANE
The intimate interaction between immune system and nerve system is known to be involved in homeostasis. We studied the orchestra betwwen these two systems in Listeria monocytogenes-infected mouse model in which the sympathetic system, especially n...