MISC

1998年5月

Branched-chain alpha-keto acid dehydrogenase kinase content in rat skeletal muscle is decreased by endurance training

BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL
  • H Fujii
  • ,
  • Y Shimomura
  • ,
  • T Murakami
  • ,
  • N Nakai
  • ,
  • T Sato
  • ,
  • M Suzuki
  • ,
  • RA Harris

44
6
開始ページ
1211
終了ページ
1216
記述言語
英語
掲載種別
出版者・発行元
ACADEMIC PRESS AUST

The activity state of branched-chain alpha-keto acid dehydrogenase complex in skeletal muscle was elevated by running exercise in trained and untrained rats, but level of this elevation was significantly greater in the former than in the latter. To elucidate the mechanism of the training effect on the exercise-induced activation of the complex, a protein amount of branched-chain alpha-keto acid dehydrogenase kinase, which is responsible for inactivation of the complex by phosphorylation, in the muscle was measured by the Western blot analysis. Endurance training decreased the content of the kinase protein in the muscle by similar to 30%, suggesting that this decrease is involved in the mechanisms for greater activation of the complex by exercise in trained rats.

Web of Science ® 被引用回数 : 16

リンク情報
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000073798800017&DestApp=WOS_CPL
ID情報
  • ISSN : 1039-9712
  • Web of Science ID : WOS:000073798800017

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