ASHIUCHI Makoto

J-GLOBAL         Last updated: Mar 19, 2019 at 15:47
 
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Name
ASHIUCHI Makoto
Affiliation
Kochi University
Section
Research and Education Faculty, Multidisciplinary Science Cluster Life and Environmental Medicine Science Unit
Job title
Associate Professor
Degree
phD(Kyoto University)

Research Areas

 
 

Academic & Professional Experience

 
1999
 - 
1999
Kochi University, Lecturer
 
1994
 - 
1999
Kochi University, Research Assistant
 
1999
   
 
- Kochi University, Associate Professor
 

Education

 
 
 - 
1994
Graduate School, Division of Agriculture, Kyoto University
 

Awards & Honors

 
2007
Encouragement Award of the Society for Biotechnology, Japan (Saito Award)
 

Published Papers

 
M. Ashiuchi et al.
FEBS(/) Lett.(/)   592 4066-4077   2018   [Refereed]
in press
M. Ashiuchi et al.
J.(/) Appl.(/) Microbiol.(/)   125 1396-1407   2018   [Refereed]
Microbial control using engineered poly-γ-glutamate-based materials.
M. Ashiuchi
Jpn.(/) J.(/) Food(/) Microbiol.(/)   35(3) 116-121   2018   [Invited]
M. Ashiuchi et al.
FEBS(/) J.(/)   284 3470-3483   2017   [Refereed]
M. Ashiuchi et al.
BioMetals(/)   29 527-534   2016   [Refereed]
M. Ashiuchi et al.
AIMS Microbiol.(/)   2 222-229   2016   [Refereed]
M. Ashiuchi et al.
Appl.(/) Environ.(/) Microbiol.(/)   83 e2710–16   2016   [Refereed]
M. Ashiuchi et al.
J.(/) Pharm.(/) Biomed.(/) Anal.(/)   116 90-93   2015   [Refereed]
M. Ashiuchi et al.
Biochem.(/) Biophys.(/) Res.(/) Commun.(/)   460 1059-1062   2015   [Refereed]

Misc

 
Enzymatic processing and genetic engineering for stereo-regular poly-γ-D-glutamate production.
M. Ashiuchi et al.
Proceedings(/), The (3rd) International Conference of D-Amino Acid Research (IDAR2017)   3 69   2017
Novel Bio-Based Plastics for Multiple Infection Prophylaxis Possessing Versatile Coating Performance
M. Ashiuchi et al.
IL21.1   2015   [Invited]
PGAIC, Novel Bio-Inspired Plastics with Anti-Infective, Wide-Applicable Coating Performance
M. Ashiuchi et al.
Preprints(/), The 10th SPSJ International Polymer Conference (IPC2014)   p.306   2014   [Invited]
D-Glutamic Acid in Microbial Exo-Polymer, Poly-γ-Glutamate.
M. Ashiuchi et al.
Proceedings(/), The (2nd) International Conference of D-Amino Acid Research (IDAR2014)   2 30   2014   [Invited]
Novel chemo-reforming of a water-soluble biopolymer, poly-γ-glutamate, giving self-healing superabsorbent materials.
M. Ashiuchi et al.
Preprints(/), The 9th SPSJ International Polymer Conference (IPC2012)   p.148   2012   [Invited]
Biosynthesis and chemical reforming of water-soluble polyamide material, poly-γ-glutamate
M. Ashiuchi et al.
Proceedings(/), The (3rd) International Conference on Bio-based Polymers   3 24   2011   [Invited]
Moonlighting function of the pgsE(/)-gene product, a novel member of the membranous enzyme complex responsible for the synthesis of D-glutamate-containing poly-γ-glutamate.
M. Ashiuchi et al.
Proceedings(/), The (1st) International Conference of D-Amino Acid Research (IDAR)   1 O-35   2009   [Invited]
Advanced applications of poly-gamma-glutamate (in Japanese)
M. Ashiuchi
BIO(/) INDUSTRY(/)   27 49   2009
Microbial and enzymatic production of chiral nylon biopolymer (in Japanese).
M. Ashiuchi
Seibutsu-kogaku Kaishi   86 73   2008
D-Glutamate and poly-gamma-glutamate synthetic system (in Japanese)
M. ashiuchi
Seikagaku   80 316   2008

Books etc

 
Occurrence and biosynthetic mechanism of poly-γ-glutamic acid
M. Ashiuchi (Part:Joint Work)
In: Microbiol.(/) Monogr.(/) (Amino-Acid Homopolymers Occurring in Nature; Y. Hamano, ed.), Springer-Verlag (Heidelberg, Germany)   2010   
Occurrence and biosynthetic mechanism of poly-gamma-glutamic acid
Microbiol.(/) Monogr.(/), Springer-Verlag (Heidelberg, Germany)   2010   
2010. In press
Enzymatic synthesis, degradation, and processing of poly-gamma-glutamate
In: Application(/) Technologies(/) and(/) New(/) Trends(/) in(/) Industrial(/) Enzymes(/)   2009   
A chiral nylon biopolymer, poly-gamma-glutamate
In: White(/) Biotechnology(/);The(/) Front(/) of(/) Energy(/) and(/) Material(/) Development(/), CMC Publishers (Tokyo, Japan)   2008   
Micro-purification and structural assays of poly-γ-glutamate, a D-amino acid-containing biopolymer.
M. Ashiuchi (Part:Joint Work)
In: D-Amino(/) Acids(/) (A New Frontior in Amino Acid and Protein Research-Practical Methods and Protocols; R. Konno, H. Brückner, A. D’Aniello, G. Fisher, N. Fujii, and H. Honma, eds), Nova Science Publishers (NY)   2007   
Poly-γ-glutamic acid.
M. Ashiuchi (Part:Joint Work)
In: Biopolymers(/) Vol.7 (S.R. Fahnestock, A. Steinbüchel, eds), Wiley-VCH (Weinheim, Germany)   2002   
In: Biopolymers(/) for(/) Medical(/) and(/) Pharmaceutical(/) Applications(/) Vol.2 (A. Steinbüchel, R.H. Marchessault, eds), Wiley-VCH (Weinheim, Germany) 2005年;In: Polysaccharides(/) and(/) Polyamides(/) in(/) the(/) Food(/) Industry(/) Vol.1 (A...
Micro-purification and structural assays of poly-gamma-glutamate, a D-amino acid-containing biopolymer.
In: D-Amino(/) Acids:(/) A(/) new(/) frontier(/) in(/) amino(/) acid(/) and(/) protein(/) research(/), Nova Science Publishers   2005   
Poly-gamma-glutamaic acid.
In: Polysaccharides(/) and(/) Polyamides(/) in(/) the(/) Food(/) Industry(/), Wiley-VCH (Weinheim, Germany)   2005   
Poly-gamma-glutamic acid.
In: Biopolymers(/) for(/) Medical(/) and(/) Pharmaceutical(/) Applications(/), Wiley-VCH (Weinheim, Germany)   2005   
Poly-gamma-glutamic acid.
In: Biotechnology(/) of(/) Biopolymers(/), Wiley-VCH (Weinheim, Germany)   2005   

Conference Activities & Talks

 
Moonlighting function of the pgsE(/)-gene product, a novel member of the membranous enzyme complex responsible for the synthesis of D-glutamate-containing poly-gamma-glutamate
The first International Conference of D-Amino Acid Research (IDAR)   2009   
Biochemical synthesis of stereo-regular poly-gamma-glutamate
JSPS–NWO Joint Seminar/The 4th Japan-Netherlands Joint Seminar on Enzyme Science and Biotechnology   2008   
Study on a bionylon polymer, poly-gamma-glutamate.
KSBB International symposium (Korea)   2007   
Salt-inducible bionylon polymer: Microbial synthesis and biochemical application.
The 10th Pacific Polymer Conference (PPC10)   2007   
Search for poly-gamma-D-glutamate inhibitor
The 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress   2006   
Enzymatic synthesis and processing of poly-gamma-glutamate.
The 8th SPSJ International Polymer Conference (IPC2005)   2005   
Characterization of membrane-associated poly-gamma-glutamate synthetase from Bacillus(/) subtilis(/) subsp. chungkookjang(/).
International Interdisciplinary Conference on Vitamins, Coenzymes, and Biofactors 2005   2005   
Glutamate racemase, a PLP-independent amino acid racemase and poly-gamma-glutamate synthesis in Bacillus(/) subtilis(/).
3rd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins   2002   
A poly-gamma-glutamate synthetic system of Bacillus(/) subtilis(/) IFO3336: Gene cloning and biochemical analysis of poly-gamma-glutamate produced by Escherichia(/) coli(/) clones.
Pacifichem 2000   2000   
Characteristics of glutamate racemase, a PLP-independent amino acid racemase.
Pacifichem 2000   2000   

Works

 
工業用微生物の開発
2009
バイオ新素材ポリグルタミン酸の量産化とバイオジェル吸水部材の応用研究
2007 - 2009
バイオリメディエーションの新戦略 - エンザイム・オーグメンテーション -
2005
高保水性バイオ素材ポリ-γ-グルタミン酸の利用に関する研究
2005 - 2006
バイオキラルナイロンをベースとする新機能材料の開発
2007
ポリ-γ-グルタミン酸のバイオプラスチック・繊維への応用
2008

Research Grants & Projects

 
Advanced molecular breeding of microorganisms
0095 (Japanese Only)
Project Year: 2006   
Study on a chiral-nylon biopolymer, poly-gamma-glutamate
0103 (Japanese Only)
Project Year: 2002   
Molecular physiology of D-amino acids
Basic Science Research on Life Science
Project Year: 1994   

Patents

 
特許JP5119435 : PROCESS FOR PRODUCING POLY-γ-GLUTAMIC ACID HAVING HIGH OPTICAL PURITY.
M. Ashiuchi et al.
特許KR10-2004-0052875 : Method for determining a molecular weight of polymer of amino acid.
M. Ashiuchi et al.
KR10-2004-0052875
特許KR10-2003-0399091 : Poly-γ-glutamate having ultra high molecular weight and method for using the same.
M. Ashiuchi et al.
特許KR10-2002-0040083 : Poly-γ-glutamate with very high molecular weight, and method for using thereof.
M. Ashiuchi et al.
特許KR10-2001-0004837 : Construction of a novel vector by the use of poly-γ-glutamic acid synthetase complex-encoding genes of Bacillus(/) subtilis(/) and its application to the bacterial cell-surface display of protein.
M. Ashiuchi et al.
特開2009-209362 : ポリ-γ-グルタミン酸架橋体の製造方法およびポリ-γ-グルタミン酸架橋体からなる成形体.
M.Ashiuchi et al.
JP2009-209326
特願2007-312800 : 細胞の形質転換方法.
M.Ashiuchi et al.
JP2007-312800 (Pending)
特表2005-500054 : Surface expression vectors having pgsBCA, the gene coding poly-γ-glutamate synthetase, and a method for expression of target protein at the surface of microorganism using vector.
M. Ashiuchi et al.
Surface expression vectors having pgsBCA(/), the gene coding poly-gamma-glutamate synthetase, and a method for expression of target protein at the surface of microorganism using vector
WO 03/014360-A1
Composition for promoting an adsorption of mineral in body comprising poly-gamma-glutamic acid having ultra high molecular weight
KR10-2003-0046898