1996年5月
Erythrocyte oxidation in artificial Babesia gibsoni infection
VETERINARY PARASITOLOGY
- ,
- ,
- ,
- 巻
- 63
- 号
- 1-2
- 開始ページ
- 1
- 終了ページ
- 7
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/0304-4017(95)00892-6
- 出版者・発行元
- ELSEVIER SCIENCE BV
We have already reported that anti-erythrocyte antibody induced by Babesia gibsoni infection (aEAb) showed higher reactivity against aged and/or oxidized erythrocytes than intact ones in vitro (Morita et al., 1995). To clarify the meaning of such a binding character of aEAb in vivo, changes in erythrocyte oxidation were observed in artificially infected dogs. The ratio of methemoglobin concentration against total hemoglobin concentration (metHb%) as the indicator of erythrocyte oxidation was increased by the artificial infection in the intact dogs, suggesting that aEAb played a more important role in erythrocyte destruction in infected dogs. Though parasitemia approximately three times higher was observed in splenectomized dogs than that in intact dogs, metHb% did not increase in the splenectomized dogs. This suggests that the spleen plays a very important role in erythrocyte oxidation in dogs infected with B. gibsoni.
- リンク情報
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- DOI
- https://doi.org/10.1016/0304-4017(95)00892-6
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/8792575
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:A1996UQ57200001&DestApp=WOS_CPL
- URL
- http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0029950759&origin=inward
- ID情報
-
- DOI : 10.1016/0304-4017(95)00892-6
- ISSN : 0304-4017
- PubMed ID : 8792575
- SCOPUS ID : 0029950759
- Web of Science ID : WOS:A1996UQ57200001