Dec, 2018
Leydig cell tumor in an Amur tiger (Panthera tigris altaica).
The Journal of veterinary medical science
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- Volume
- 81
- Number
- 2
- First page
- 186
- Last page
- 189
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1292/jvms.18-0573
A 14-year and 8-month-old intact male Amur tiger presented with an enlarged left testis, measuring 5.7 × 5.5 × 4.5 cm. The cut surface was mottled dark red to reddish brown in color. Microscopically, the enlarged left testis comprised round or polygonal neoplastic cells arranged in a diffuse sheet pattern. These neoplastic cells had a hyperchromatic nucleus and an abundant eosinophilic cytoplasm. Immunohistochemically, these neoplastic cells were positive for vimentin, chromogranin A, synaptophysin, melan-A, inhibin-α, and S100 and negative for desmin and WT-1. Based on these morphological and immunohistochemical findings, the tumor was diagnosed as a Leydig cell tumor.
- Link information
- ID information
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- DOI : 10.1292/jvms.18-0573
- ISSN : 0916-7250
- Pubmed ID : 30541983
- Pubmed Central ID : PMC6395220