論文

査読有り
2017年2月

Malignant Oestrogen-producing Teratoma in a Cat

JOURNAL OF COMPARATIVE PATHOLOGY
  • Y. Machida
  • ,
  • M. Michishita
  • ,
  • M. Wada
  • ,
  • T. Hori
  • ,
  • E. Kawakami
  • ,
  • H. Yoshimura
  • ,
  • K. Ohkusu-Tsukada
  • ,
  • K. Taya
  • ,
  • K. Takahashi

156
2-3
開始ページ
178
終了ページ
182
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jcpa.2016.11.273
出版者・発行元
ELSEVIER SCI LTD

A 5-year-old female domestic shorthair cat was presented with abdominal distension and serum biochemical evaluation indicated a high concentration of oestradiol (32.81 pg/ml). Exploratory laparotomy revealed a large cystic mass in the right ovary with cystic fluid containing a high level of oestradiol (18.80 pg/ml). The tumour was composed of immature neuroectodermal tissue, mature cartilage, smooth muscle, adipose tissue and aggregated, poorly differentiated mesenchymal cells. It contained cysts of various sizes that were lined by epithelium of different types. The basal layer of the lining epithelium was shown to express aromatase by immunohistochemistry. The findings suggest that this was a novel, malignant, oestrogen-secreting teratoma and that the aromatase-positive, neoplastic cells may have been the source of elevated levels of serum oestrogen. (C) 2016 Elsevier Ltd. All rights reserved.

Web of Science ® 被引用回数 : 1

リンク情報
DOI
https://doi.org/10.1016/j.jcpa.2016.11.273
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000399266400008&DestApp=WOS_CPL
URL
https://www.ncbi.nlm.nih.gov/pubmed/28017339

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