原田真市 (Shin'ichi Harada) - マイポータル

基本情報

所属: 金沢大学医薬保健研究域医学系教育研究支援センター准教授

学位: 博士(医学)(金沢大学)
修士(工学)(豊橋技術科学大学)

J-GLOBAL ID: 200901065842977587
researchmap会員ID: 1000193079

外部リンク: http://web.kanazawa-u.ac.jp/~med59/

研究キーワード

研究分野

ライフサイエンス / 医化学 /

学歴

受賞

1999年

第１４回基礎医学医療研究助成金
1999年

第１７回日本生化学会北陸支部奨励賞（米山賞）

論文

GLUT1 inhibition by BAY-876 induces metabolic changes and cell death in human colorectal cancer cells.

Masato Hayashi, Keishi Nakamura, Shinichi Harada, Mariko Tanaka, Akiko Kobayashi, Hiroto Saito, Toshikatsu Tsuji, Daisuke Yamamoto, Hideki Moriyama, Jun Kinoshita …

BMC cancer 25(1) 716-716 2025年4月17日
ASO Visual Abstract: Hypoxia-Induced CD36 Expression in Gastric Cancer Cells Promotes Peritoneal Metastasis via Fatty Acid Uptake.

Tatsuya Aoki, Jun Kinoshita, Seiichi Munesue, Toshihide Hamabe-Horiike, Takahisa Yamaguchi, Yusuke Nakamura, Koichi Okamoto, Hideki Moriyama, Keishi Nakamura, Shinichi Harada …

Annals of surgical oncology 2023年2月15日
Hypoxia-Induced CD36 Expression in Gastric Cancer Cells Promotes Peritoneal Metastasis via Fatty Acid Uptake.

Tatsuya Aoki, Jun Kinoshita, Seiichi Munesue, Toshihide Hamabe-Horiike, Takahisa Yamaguchi, Yusuke Nakamura, Koichi Okamoto, Hideki Moriyama, Keishi Nakamura, Shinichi Harada …

Annals of surgical oncology 2022年8月30日
Adipocytes contribute to tumor progression and invasion of peritoneal metastasis by interacting with gastric cancer cells as cancer associated fibroblasts.

Toshihide Hamabe-Horiike, Shin-Ichi Harada, Kyoko Yoshida, Jun Kinoshita, Takahisa Yamaguchi, Sachio Fushida

Cancer reports (Hoboken, N.J.) e1647 2022年6月12日
Crosstalk between cancer-associated fibroblasts and immune cells in peritoneal metastasis: inhibition in the migration of M2 macrophages and mast cells by Tranilast.

Yusuke Nakamura, Jun Kinoshita, Takahisa Yamaguchi, Tatsuya Aoki, Hiroto Saito, Toshihide Hamabe-Horiike, Shinichi Harada, Sachiyo Nomura, Noriyuki Inaki, Sachio Fushida

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2022年1月7日
Glial cell type-specific gene expression in the mouse cerebrum using the piggyBac system and in utero electroporation.

Toshihide Hamabe-Horiike, Kanji Kawasaki, Masataka Sakashita, Chihiro Ishizu, Tomokazu Yoshizaki, Shin-Ichi Harada, Keiko Ogawa-Ochiai, Yohei Shinmyo, Hiroshi Kawasaki

Scientific Reports 11(1) 4864 2021年3月1日査読有り
Interleukin-17A derived from mast cells contributes to fibrosis in gastric cancer with peritoneal dissemination.

Katsuya Gunjigake, Jun Kinoshita, Takahisa Yamaguchi, Hiroto Saito, Daisuke Fujimori, Toshihide Horiike, Shinichi Harada, Hidehiro Tajima, Itasu Ninomiya, Tetsuo Ohta …

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24(1) 31-44 2021年1月
Interactions Between Neutrophils and Platelets in the Progression of Acute Pancreatitis.

Tomokazu Tokoro, Isamu Makino, Shinichi Harada, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Jun Kinoshita, Keishi Nakamura, Tomoharu Miyashita, Hidehiro Tajima …

Pancreas 49(6) 830-836 2020年7月
Effect of Oral Branched-Chain Amino Acids and Glutamine Supplementation on Skeletal Muscle Atrophy After Total Gastrectomy in Rat Model.

Haba Y, Fujimura T, Oyama K, Kinoshita J, Miyashita T, Fushida S, Harada S, Ohta T

The Journal of surgical research 243 281-288 2019年11月査読有り
The role of peripheral corticotropin-releasing factor signaling in a rat model of stress-induced gastric hyperalgesia.

Kozakai Y, Hori K, Aye-Mon A, Okuda H, Harada SI, Hayashi K, Ozaki N

Biochemical and biophysical research communications 519(4) 797-802 2019年11月査読有り
アディポサイトは胃癌微小環境において腹膜播種成立に関与する(Adipocytes contribute peritoneal metastasis formation in gastric cancer microenvironment)

伏田幸夫, 堀池俊秀, 原田真市, 山口貴久, 木下淳, 二宮致, 太田哲生

日本癌学会総会記事 77回 344-344 2018年9月
Phosphodiesterase III inhibitor attenuates rat sinusoidal obstruction syndrome through inhibition of platelet aggregation in Disse's space.

Takashi Miyata, Hidehiro Tajima, Miki Hirata, Shin-Ichi Nakanuma, Isamu Makino, Hironori Hayashi, Katsunobu Oyama, Tomoharu Miyashita, Hiroyuki Takamura, Itasu Ninomiya …

Journal of gastroenterology and hepatology 33(4) 950-957 2018年4月査読有り
Importance of human peritoneal mesothelial cells in the progression, fibrosis, and control of gastric cancer: inhibition of growth and fibrosis by tranilast

Hiroto Saito, Sachio Fushida, Shinichi Harada, Tomoharu Miyashita, Katsunobu Oyama, Takahisa Yamaguchi, Tomoya Tsukada, Jun Kinoshita, Hidehiro Tajima, Itasu Ninomiya …

Gastric Cancer 21(1) 55-67 2018年1月1日査読有り
The effect of HIF-1α and PKM1 expression on acquisition of chemoresistance.

Okazaki M, Fushida S, Tsukada T, Kinoshita J, Oyama K, Miyashita T, Ninomiya I, Harada S, Ohta T

Cancer management and research 10 1865-1874 2018年査読有り
Low-dose paclitaxel suppresses the induction of M2 macrophages in gastric cancer.

Yamaguchi T, Fushida S, Yamamoto Y, Tsukada T, Kinoshita J, Oyama K, Miyashita T, Tajima H, Ninomiya I, Munesue S …

Oncology reports 37(6) 3341-3350 2017年6月査読有り
Extravasated platelet aggregation in the livers of rats with drug‑induced hepatic sinusoidal obstruction syndrome.

Hirata M, Tajima H, Miyashita T, Miyata T, Nakanuma S, Makino I, Hayashi H, Oyama K, Takamura H, Ninomiya I …

Molecular medicine reports 15(5) 3147-3152 2017年5月査読有り
Establishing a xenograft mouse model of peritoneal dissemination of gastric cancer with organ invasion and fibrosis

Mitsuyoshi Okazaki, Sachio Fushida, Shinichi Harada, Tomoya Tsukada, Jun Kinoshita, Katsunobu Oyama, Tomoharu Miyashita, Itasu Ninomiya, Tetsuo Ohta

BMC CANCER 17(1) 23 2017年1月査読有り
Metformin inhibits the radiation-induced invasive phenotype of esophageal squamous cell carcinoma

Akira Nakayama, Itasu Ninomiya, Shinichi Harada, Tomoya Tsukada, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hironori Hayashi …

INTERNATIONAL JOURNAL OF ONCOLOGY 49(5) 1890-1898 2016年11月査読有り
Valproic acid inhibits irradiation-induced epithelial-mesenchymal transition and stem cell-like characteristics in esophageal squamous cell carcinoma

Ayako Kanamoto, Itasu Ninomiya, Shinichi Harada, Tomoya Tsukada, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hironori Hayashi …

INTERNATIONAL JOURNAL OF ONCOLOGY 49(5) 1859-1869 2016年11月査読有り
Tumor-associated macrophages of the M2 phenotype contribute to progression in gastric cancer with peritoneal dissemination

Takahisa Yamaguchi, Sachio Fushida, Yasuhiko Yamamoto, Tomoya Tsukada, Jun Kinoshita, Katsunobu Oyama, Tomoharu Miyashita, Hidehiro Tajima, Itasu Ninomiya, Seiichi Munesue …

GASTRIC CANCER 19(4) 1052-1065 2016年10月査読有り