TATSUKA Masaaki

J-GLOBAL         Last updated: Mar 17, 2015 at 21:28
 
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Name
TATSUKA Masaaki
Affiliation
Prefectural University of Hiroshima
Job title
Professor
Other affiliation
Hiroshima UniversityHiroshima University

Research Areas

 
 

Academic & Professional Experience

 
1996
   
 
- Research Insitute for Radiation Biology and Medicine, Hiroshima University
 
1995
 - 
1996
 Cancer Research Institute, Kanazawa University
 
1989
 - 
1994
 Biology Section, Oak Ridge National Laboratory
 

Education

 
 
 - 
1989
Oncogene Research, Graduate School, Division of Medicine, Osaka University
 

Published Papers

 
Okamoto M, Fukutomi R, Hori M, Tsuno T, Fujii M, Tatsuka M. Evaluation of carcinogenic/co-carcinogenic activity of mokusaku-eki, a wood charcoal by-product used as a folk remedy, in BALB/c 3T3 cells.
Okamoto M, Fukutomi R, Hori M, Tsuno T, Fujii M, Tatsuka M.
J Life Environ Sci   5(1) 9-17   Mar 2013   [Refereed]
Jiang Y-S, Maeda M, Okamoto M, Fujii M, Fukutomi R, Hori M, Tatsuka M.
Int J Oncol   42(2) 460-468   Feb 2013   [Refereed]
Hori M, Miki T, Okamoto M, Yazama F, Konishi H, Kaneko H, Shimamoto F, Ota T, Temme A, Tatsuka M.
PLoS One   8(2) e55710   Feb 2013   [Refereed]
Tuncel H, Tanaka S, Oka S, Nakai S, Fukutomi R, Okamoto M, Ota T, Kaneko H, Tatsuka M, Shimamoto F.
Int J Oncol   41(6) 2079-2086   Dec 2012   [Refereed]
Radiation in food: Current estimates of the health effects of low-dose ionizing radiation from contaminated food and drink caused by the Tokyo Electric Power Company Fukushima Daiichi nuclear power plant accident.
Okamoto M, Koga S, Fujii M, Koya S, Shimamoto F, Matuda N, Tatsuka M.
New Food Industry   54(3) 1-17   May 2012   [Refereed]
Okamoto M, Hirata S, Sato S, Koga S, Fujii M, Qi G, Ogawa I, Takata T, Shimamoto F, Tatsuka M.
DNA Cell Biol   31(5) 660-671   May 2012   [Refereed]
Tuncel H, Shimamoto F, Qi G, Aoki E, Jikihara H, Nakai S, Takata T, Tatsuka M.
Oncol Lett   3(5) 1109-1114   May 2012   [Refereed]
Chromosomal passenger complex: its structure and function.
Okamoto M, Fujii M, Tatsuka M.
Seitai-no-Kagaku   62(5) 460-463   Sep 2011   [Invited]
Overview of Aurora kinases.
Okamoto M, Fujii M, Tatsuka M.
Seitai-no-Kagaku   62(5) 464-465   Sep 2011   [Invited]

Misc

 
Own work introduction: Radiation in food: Current estimates of the health effects of low-dose ionizing radiation from contaminated food and drink caused by the Tokyo Electric Power Company Fukushima Daiichi nuclear power plant accident.
Tatsuka M.
J Life Environ Sci   4(1) 73-74   Mar 2012
The journal of the Hiroshima Medical Association   61(4) 312-314   2008
SAI Kouei, TUNCEL Handan, AOKI Eriko, TANAKA Shinnji, OUKA Sirou, TAKAHASI Ryoji, KANAKO Iwao, TATSUKA Haruo, TAKATA Takashi, SHIMAMOTO Fumio
Bulletin of the Faculty of Human Culture and Science, Prefectural University of Hiroshima   1 47-60   Mar 2006
Survivin is a bifunctional protein that suppresses apoptosis and regulates cell division. It is expressed in various human cancers, but not in most normal adult human tissues, and has therefore garnered great interest as a potential drug target. T...
Cationic liposomes with plasmid DNA influence cancer metastatic capability
Anticancer Res.   22(6C) 4049-4052   2002
Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability
Cancer Res   62(18) 5168-5177   2002
Tatsuka Masaaki, Kawai Hidehiko, Kitao Hiroyuki, Kato Tomohisa
Nagasaki Igakkai zasshi = Nagasaki medical journal   75 291-293   Sep 2000
Specific Inhibitors of tyrosine-specific kinase : properties of 4-hydroxycinnamanide derivatives in vitro.
Cancer Res.   49(9) 2374-2378   1989
High invasiveness associated with augmentation of motility in a fos-transformed highly metasfatic rat 3Y1 cell line.
Cancer Res.   49(23) 6738-6744   1989
Multinuclearity and increased polidy caused by overexpression of the aurora-and Ipl1-like mid body-associated protein mitotic kinase in human cancer cells
Cancer Res.   58(21) 4811-4816   1998
Functional suppression of integrin B4-mediated adhesion caused by in vivo sequential selection for cancer cell intravasation.
Anticancer Res.   21(1) 205-211   2001
Journal of Biological Chemistry   279(13) 12997-13003   2004
Anticarcinogenic effect and enhancement of metastatic potential of BALB/c 3T3 cells by ginsenoside Rh2.
Jpn. J. Cancer Res.   92(11) 1184-1189   2001
J. Biol. Chem.   276(49) 46219-46224   2001
Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycleInteraction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic ce...
Gene   242(1/2) 321-330   2000
Down-regulation of NFκB is required for p53-dependent apoptosis in X-irradiated mouse lymphoma cells and thmocytes.
Cancer Res.   59(24) 6038-6041   1999
Mitotic kinase expression and colorectal cancer progression.
J. Natl. Cancer Inst.   91(13) 1160-1162   1999
G1 phase-specific suppressino of the Cdk2 activity by ginsenoside Rh2 in cultured murine cells.
Life Sci.   60(2) PL39-44   1997
Structural organization of mouse DNA repair gene, N-methylpurine-DNA glycosylase.
DNA Cell Biol.   14(1) 37-45   1995
Expression of platelet-derived growth factor-independent phenotypes in BALB/c 3T3 cell variant with high susceptibility to chemically or physically induced neoplastic transformation: dissociation from activation of protein kinase C.
Cancer Res.   52(15) 4232-4241   1992
A tyrosine-specific protein kinase inhibitor, α-cyano-3-ethoxy-4-hydroxy-5-phenylthiomethylcinnamamide, block the phosphorylation of tyrosine kinase substrate in intact cells.
Jpn. J. Cancer Res.   81(6-7) 645-652   1990
Quantitative measurement of cell motility associated with transformed phenotype.
Jpn. J. Cancer Res.   80(5) 408-412   1989
Electroporation-mediated transfection of mammalian cells with crude plasmid DNA preparations.
Genet. Anal.   12(2) 113-117   1995
Mechanisms of prolongation of survival rate in tumor bearing mice and rats using 5-fluorouracil in combination with various kinds of herb medicine
J. Med. Pharm. Soc. WAKANYAKU   1(1) 66-67   1984
Myosin II regulatory light chain as a novel substrate for AIM-1, an aurora/Ipl1p-related kinase from rat.
J. Biochem.   128(6) 903-907   2000
An approach to prolongation of survival rate in tumor baring mice using 5-fluorouracil in combination with various kinds of herb medicine.
10 1853-1865   1983
Aurora kinases and cell division
Radiation Biology Research Communications   39(4) 353-372   2004

Books etc

 
Biological makers for transformation and mutation
1990   
Aurora shed a light over cell division mechanisms. In: Dynamical Genetics
Research Signpost   2005   

Conference Activities & Talks

 
Survivin, an inhibitor of anoikis, induces activation of nuclear factor (NF)-kappaB pathway
Hori M, Okamoto M, Fukutomi R, Tsuno T, Fujiwara M, Okada K, Ota T, Tatsuka M.
The 72nd Annual Meeting of the Japanese Cancer Association   Oct 2013   
PARP6-C, a splice variant of PARP6, is upregulated after X-irradiation, and its forced overexpression prevents apoptosis
Fukutomi R, Okamoto M, Hori M, Tsuno T, Fujiwara M, Okada K, Ota T, Tatsuka M.
The 72nd Annual Meeting of the Japanese Cancer Association   Oct 2013   
Knockdown of NSUN2 induces accumulation of cells with higher ploidy and micronuclei after X-irradiation
Okamoto M, Okada K, Hori M, Fukutomi R, Tsuno T, Fujiwara M, Ota T, Tatsuka M.
The 72nd Annual Meeting of the Japanese Cancer Association   Oct 2013   
Role of caspase-3 cleaved RhoGDIβ in radiation-induced apoptosis of macrophages
Ota T, Okamoto M, Fukutomi R, Hori M, Tsuno T, Fujiwara M, Okada K, Tatsuka M.
The 72nd Annual Meeting of the Japanese Cancer Association   Oct 2013   
Survivin represses anokis via XIAP/IkB-alpha/NF-kappaB signaling pathway
Hori M, Okamoto M, Fukutomi R, Tsuno T, Fujii M, Fujii M, Ota T, Tatsuka M.
The 22nd Annual Meeting of the Japanese Association for Metastasis Research   Jul 2013   
The caspase-3-induced RhoGDIbeta variant perturbs spindle orientation in wound-healing assay
Okamoto M, Hori M, Fukutomi R, Tsuno T, Fujii M, Fujii M, Ota T, Tatsuka M.
The 22nd Annual Meeting of the Japanese Association for Metastasis Research   Jul 2013   
Hypoxia-induced MOB2A associates with Krs and sequestrates its kinase activity
Fujiwara M, Fujii M, Okamoto M, Hori M, Fukutomi R, Tsuno T, Ota T, Tatsuka M.
The 22nd Annual Meeting of the Japanese Association for Metastasis Research   Jul 2013   
Suppression of experimental metastasis of B16 melanoma cells by oral administration of lapachol
Ota T, Okamoto M, Hori M, Fukutomi R, Tsuno T, Fujiwara M, Fujii M, Tatsuka M.
The 22nd Annual Meeting of the Japanese Association for Metastasis Research   Jul 2013   
Current Projects: Laboratory of Radiation Genome Systems Biology
Tatsuka M.
The 10th Symposium of Kobe Wine Castle   Dec 2012   
Hypoxia-induced changes in the expression of MOB1-related proteins in HeLa cells.
Fujii M, Fujiwara M, Fujiwara K,Ota T, Tatsuka M.
The 10th Symposium of Kobe Wine Castle   Dec 2012   
Knockdown of NSUN2 methylase increases radiation-induced multinuclearity in HeLa cells.
Okamoto M, Tsuno T, Kitahara A, Ota T, Shimamoto F, Tatsuka M.
The 10th Symposium of Kobe Wine Castle   Dec 2012   
Survivin, a member of chromosomal passenger proteins, suppresses anoikis and its expression is associated with metastatic disease of human.
Hori M, Utsumi R, Hirata A, Okamoto M, Ota T, Shimamoto F, Tatsuka M.
The 10th Symposium of Kobe Wine Castle   Dec 2012   
RNA methylase NSUN2 is overexpressed with gene copy number gain in human cancers and provides radioprotection
Okamoto M, Fukutomi R, Hori M, Tsuno T, Fujii M, Kaneko H, Shimamoto F, Ota T, Tatsuka M.
The 71nd Annual Meeting of the Japanese Cancer Association   Sep 2012   
RhoGDIbeta lacking N-terminal regulating domain decreases the circulating tumor cells in mouse lung carcinoma cells
Ota T, Fujii M, Okamoto M, Tatsuka M.
The 71nd Annual Meeting of the Japanese Cancer Association   Sep 2012   
Altered expression of monopolar spindle one binder family proteins under hypoxic conditions in HeLa cells
Fujii M, Hori M, Fukutomi R, Tsuno T, Okamoto M, Ota T, Tatsuka M.
The 71nd Annual Meeting of the Japanese Cancer Association   Sep 2012   
Expression of Survivin proteins fused to different tag sequences has different abilities to protect against anoikis.
Hori M, Fukutomi R, Tsuno T, Fujii M, Okamoto M, Kaneko H, Shimamoto F, Ota T, Tatsuka M.
The 71nd Annual Meeting of the Japanese Cancer Association   Sep 2012   
Altered expression of Monopolar spindle one binders under hypoxic conditions in HeLa cells
Fujii M, Ota T, Tatsuka M.
The 21nd Annual Meeting of the Japanese Association for Metastasis Research   Jun 2012   
Suppression of intravasation by RhoGDI-beta lacking N-terminal regulating do main in 3LL cells
Ota T, Fujii M, Tatsuka M.
The 21nd Annual Meeting of the Japanese Association for Metastasis Research   Jun 2012   
RhoGDIbeta produced by caspase-3 activation inhibits directional cell migration
Tatsuka M, Fujii M, Ota T.
The 21nd Annual Meeting of the Japanese Association for Metastasis Research   Jun 2012   
Localization of GDIbeta in the basal body region of Tetrahymena thermophila
Ota T, Tatsuka M, Sugai T.
The 22nd Annual Meeting of the Japan Cytometry Society   Jun 2012   
Knockdown of SAKI/NSUN2/MISU increases radiation-induced multinuclearity in HeLa cells
Okamoto M, Fujii M, Ota T, Shimamoto F, Tatsuka M.
The 9th Symposium of Kobe Wine Castle   Dec 2011   
Radioactive Contamination in Food
Tatsuka M.
Special Seminar - Fresta Hiroshima   Nov 2011   
Radioactive Contamination in Food
Tatsuka M.
Special Seminar - Medical Research Institute, Kanazawa Medical University   Nov 2011   
Caspase-3-generated N-terminal deleted form of RhoGDIbeta perturbs directional sensing in HeLa cells wound healing
Koga S, Okamoto M, Fujii M, Koya S, Miki T, Watanabe K, Mori T, Ota T, Tatsuka M.
The 70nd Annual Meeting of the Japanese Cancer Association   Oct 2011   
Knock-down of tRNA methyltransferase SAKI/NSUN2/MISU in HeLa cells increases multinuclearity after X-irradiation
Okamoto M, Fujii M, Koya S, Koga S, Miki T, Watanabe K, Shimamoto F, Ota T, Tatsuka M.
The 70nd Annual Meeting of the Japanese Cancer Association   Oct 2011   
Survivin and anoikis: an analysis by site-directed mutagenesis
Miki T, Okamoto M, Fujii M, Koga S, Koya S, Watanabe K, Shimamoto F, Ota T, Tatsuka M.
The 70nd Annual Meeting of the Japanese Cancer Association   Oct 2011   
PARP-6 belonging to the class of mono(ADP-ribosyl)transferases is a negative regulator of cell proliferation
Watanabe K, Koya S, Okamoto M, Fujii M, Koga S, Miki T, Ota T, Shimamoto F, Tatsuka M.
The 70nd Annual Meeting of the Japanese Cancer Association   Oct 2011   
RhoGDIbeta localizes at centrosome and functions in mitotic processes in cancer cells
Maeda M, Koga S, Okamoto M, Miki T, Watanabe K, Tatsuka M, Ota T.
he 70nd Annual Meeting of the Japanese Cancer Association   Oct 2011   
Clinicopathological study of PARP6 expression in advanced serrated adenocarcinoma
Shimamoto F, Qi G, Tatsuka M.
The 70nd Annual Meeting of the Japanese Cancer Association   Oct 2011   
Intracellular localization of RhoGDIbeta in cancer cells
Ota T, Okamoto M, Koga S, miki T, Tatsuka M.
The 21nd Annual Meeting of the Japan Cytometry Society   Jun 2011   
Survivin is a valuable predictor for colorectal cancer metastasis
Tatsuka M, Ota T, Shimamoto F.
The 20nd Annual Meeting of the Japanese Association for Metastasis Research   Jun 2011   
RhoGDIbeta contributes to centrosomal function and its relevance to cancer progression
Ota T, Tatsuka M.
The 20nd Annual Meeting of the Japanese Association for Metastasis Research   Jun 2011   

Research Grants & Projects

 
AIM-1 and its related kinases
The Other Research Programs
Ionizing radiation-induced apoptosis
The Other Research Programs
Molecule Mechanisms of Cancer Metastasis
The Other Research Programs

Patents

 
Cancer cells capable of tumorigenesis but incapable of infiltration and metastasis, process for preparing the same, and method for screening gene relating to metastasis by the same
WO 97/32009
Cell cycle-regulating proteins
WO 99/09160