山口直人 (Naoto Yamaguchi) - マイポータル - researchmap

基本情報

所属: 千葉大学薬学部大学院薬学研究院研究院ゲノム機能学講座分子細胞生物学研究室千葉大学

学位: 博士(東京大学)

J-GLOBAL ID: 200901008487230951
researchmap会員ID: 1000222531

外部リンク: http://www.p.chiba-u.ac.jp/lab/maku/index.html

研究キーワード

1

分子細胞生物学生化学細胞情報伝達機構癌生物

MISC

118

Role of Src-family kinases in formation of the cortical actin cap at the dorsal cell surface

Takahisa Kuga, Masaki Hoshino, Yuji Nakayama, Kousuke Kasahara, Kikuko Ikeda, Yuuki Obata, Akinori Takahashi, Yukihiro Higashiyama, Yasunori Fukumoto, Naoto Yamaguchi

EXPERIMENTAL CELL RESEARCH 314(10) 2040-2054 2008年6月
Role of Src-family kinases in formation and trafficking of macropinosomes. (共著)

KASAHARA Kousuke, NAKAYAMA Yuji, SATO Izumi, IKEDA Kikuko, HOSHINO Masaki, ENDO Takeshi, YAMAGUCHI Naoto

J. Cell. Physiol. 211(1) 220-232 2007年4月
Src signaling regulates completion of abscission in cytokinesis through ERK/MAPK activation at the midbody (共著)

KASAHARA Kousuke, NAKAYAMA Yuji, NAKAZATO Yoshimi, IKEDA Kikuko, KUGA Takahisa, YAMAGUCHI Naoto

J. Biol. Chem. 282(8) 5327-5339 2007年2月
Trophoblast cell activation by trophinin ligation: possible role in human embryo implantation. (共著)

Proc. Natl. Acad. Sci. USA 104(10) 3799-3804 2007年
Involvement of the N-terminal unique domain of Chk tyrosine kinase in Chk-induced tyrosine phosphorylation in the nucleus. (共著)

NAKAYAMA Yuji, KAWANA Akiko, IGARASHI Asae, YAMAGUCHI Naoto

Exp. Cell Res. 312(12) 2252-2263 2006年7月
Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress (共著)

MATSUDA Daisuke, NAKAYAMA Yuji, HORIMOTO Shinya, KUGA Takahisa, IKEDA Kikuko, KASAHARA Kousuke, YAMAGUCHI Naoto

Exp. Cell Res 312(7) 1205-1217 2006年4月
Expression and muscarinic receptor coupling of Lyn kinase in cultured human airway smooth muscle cells. (共著)

Physiol.-Lung Cell. Mol. Physiol 290(3) L492-L500 2006年3月
Apical cell adhesion molecule, trophinin, localizes to the nuclear envelope. (共著)

AOYAMA Junya, NAKAYAMA Yuji, SUGIYAMA Daijiro, SABURI Sakura, NADANO Daita, FUKUDA Michiko N, YAMAGUCHI Naoto

FEBS Lett. 579(28) 6326-6332 2005年11月
Multi-lobulation of the nucleus in prolonged S phase by nuclear expression of Chk tyrosine kinase. (共著)

NAKAYAMA Yuji, YAMAGUCHI Naoto

Exp. Cell Res. 304(2) 570-581 2005年4月
Isolation of austroinulin possessing cell cycle inhibition activity from Blumea glomerata and revision of its absolute configuration. (共著)

Planta Med. 70(12) 1170-1173 2004年12月
New chlorogenin hexasaccharide isolated from Agave fourcroydes with cytotoxic and cell cycle inhibitory activities. (共著)

Bioorg. Med. Chem. 12(14) 3841-3845 2004年7月
Trafficking of Lyn through the Golgi caveolin involves the charged residues on ・｡E and ・｡I helices in the kinase domain. (共著)

KASAHARA K, NAKAYAMA Y, IKEDA K, FUKUSHIMA Y, MATSUDA D, HORIMOTO S, YAMAGUCHI N

J. Cell Biol. 165(5) 641-652 2004年6月
Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Archyria ferruginea and Tubifera casparyi (共著)

NAKATANI S, NAOE A, YAMAMOTO Y, YAMAUCHI T, YAMAGUCHI N, ISHIBASHI M

Bioorg. Med. Chem. Lett. 13(17) 2879-2881 2003年9月
Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes. (共著)

Immunol. Lett. 84 117-124 2002年
Residue aspartate-147 from the third transmembrane region of Na+/H+ antiporter NhaB of Vibrio alginolyticus plays a role in its activity. (共著)

NAKAMURA T, FUJISAKI Y, ENOMOTO H, NAKAYAMA Y, TAKABE T, YAMAGUCHI N, UOZUMI N

J. Bacteriol. 183(19) 5762-5767 2001年
Overexpression of the Csk homologous kinase (Chk tyrosine kinase) induces multinucleation: A possible role for chromosome-associated Chk in chromosome dynamics. (共著)

J. Cell Sci. 114(9) 1631-1641 2001年
Suppression of GD1・｡ ganglioside-mediated tumor metastasis by liposomalized WHW-peptide (共著)

TAKIKAWA M, KIKKAWA H, ASAI T, YAMAGUCHI N, ISHIKAWA D, TANAKA M, OGINO K, TAKI T, OKU N

FEBS Lett. 466(2/3) 381-384 2000年
Novel association of the Src family kinases, Hck and c-Fgr, with CCR3 receptor stimulation: a possible mechanism for eotaxin-induced human eosinophil chemotaxis. (共著)

EL‐SHAZLY A, YAMAGUCHI N, MASUYAMA K, SUDA T, ISHIKAWA T

Biochem. Biophys. Res. Commun. 264(1) 163-170 1999年
A common signaling pathway via Syk and Lyn tyrosine kinases generated from capping of the sialomucins CD34 and CD43 in immature hematopoietic cells. (共著)

Blood 93 3723-3725 1999年
Induction of cell shape changes through activation of the interleukin-3 common ・｢-chain receptor by the RON receptor-type tyrosine kinase. (共著)

MERA A, SUGA M, ANDO M, SUDA T, YAMAGUCHI N

J. Biol. Chem. 274(22) 15766-15774 1999年

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所属学協会

5

共同研究・競争的資金等の研究課題

2