吉川祐子 (Yoshikawa Yuko) - マイポータル

基本情報

所属: 同志社大学

学位: 薬学（博士）

J-GLOBAL ID: 200901032575295913
researchmap会員ID: 1000223064

研究キーワード

①長鎖DNAの高次構造、単一分子観察 ②蛍光顕微鏡 ③環境ストレス応答、 ④DNA損傷、⑤抗がん剤

研究分野

経歴

2010年4月

立命館大学総合理工学研究機構（現総合科学技術研究機構）・チェアプロフェッサー
2009年9月 - 2010年3月

立命館大学総合理工学研究機構・研究員
2007年4月 - 2009年8月

環太平洋大学次世代教育学部・教授
2003年4月 - 2007年3月

名古屋文理短期大学（現名古屋文理大学短期大学部）・教授
1998年4月 - 2003年3月

名古屋文理短期大学・助教授
1996年10月 - 1998年3月

名古屋文理短期大学・専任講師
立命館大学総合科学技術研究機構, 教授

学歴

- 1988年3月

徳島大学大学院, 薬学研究科

論文

Different Effects of Cisplatin and Transplatin on the Higher-Order Structure of DNA and Gene Expression

International Journal of Molecular Sciences 21 34 2020年1月査読有り
Specific effects of antitumor active norspermidine on the structure and function of DNA

Scientific Reports 9 14971 2019年10月査読有り
Branched-Chain Polyamine Found in Hyperthermophiles Induces Unique Temperature-Dependent Structural Changes in Genome-Size DNA

Takashi Nishio, Yuko Yoshikawa, Wakao Fukuda, Naoki Umezawa, Tsunehiko Higuchi, Shinsuke Fujiwara, Tadayuki Imanaka, Kenichi Yoshikawa

ChemPhysChem 19 2299-2304 2018年査読有り
Opposite effect of polyamines on In vitro gene expression: Enhancement at low concentrations but inhibition at high concentrations

Ai Kanemura, Yuko Yoshikawa, Wakao Fukuda, Kanta Tsumoto, Takahiro Kenmotsu, Kenichi Yoshikawa

PLOS ONE 13 e0193595 2018年査読有り
Conformational transition of DNA by dinuclear Pt(II) complexes causes cooperative inhibition of gene expression

Yuta Shimizu, Yuko Yoshikawa, Takahiro Kenmotsu, Seiji Komeda, Kenichi Yoshikawa

CHEMICAL PHYSICS LETTERS 678 123-129 2017年6月査読有り
A single-molecule assessment of the protective effect of DMSO against DNA double-strand breaks induced by photo-and g-ray-irradiation, and freezing

Masami Noda, Yue Ma, Yuko Yoshikawa, Tadayuki Imanaka, Toshiaki Mori, Masakazu Furuta, Tatsuaki Tsuruyama, Kenichi Yoshikawa

Scientific Reports 7 8557 2017年査読有り
Double-Strand Breaks in a Genome-Sized DNA Caused by Ultrasound: High-Frequency Pulsing Induces Greater Damage than CW Sonication and Low-Frequency Pulsing Causes Less Damage

Rinko Kubota, Yusuke Yamashita, Takahiro Kenmotsu, Yuko Yoshikawa, Kenji Yoshida, Yoshiaki Watanabe, Tadayuki Imanaka, Kenichi Yoshikawa

ChemPhysChem 18 959-964 2017年査読有り
Specific Conformational Change in Giant DNA Caused by Anticancer Tetrazolato-Bridged Dinuclear Platinum(II) Complexes: Middle-Length Alkyl Substituents Exhibit Minimum Effect

Seiji Komeda, Hiroki Yoneyarna, Masako Uemura, Akira Muramatsu, Naoto Okamoto, Hiroaki Konishi, Hiroyuki Takahashi, Akimitsu Takagi, Wakao Fukuda, Tadayuki Imanaka …

INORGANIC CHEMISTRY 56(2) 802-811 2017年1月査読有り
Naturally occurring branched-chain polyamines induce a crosslinked meshwork structure in a giant DNA

Akira Muramatsu, Yuta Shimizu, Yuko Yoshikawa, Wakao Fukuda, Naoki Umezawa, Yuhei Horai, Tsunehiko Higuchi, Shinsuke Fujiwara, Tadayuki Imanaka, Kenichi Yoshikawa

JOURNAL OF CHEMICAL PHYSICS 145(23) 235103 2016年12月査読有り
Divalent cation shrinks DNA but inhibits its compaction with trivalent cation

Chika Tongu, Takahiro Kenmotsu, Yuko Yoshikawa, Anatoly Zinchenko, Ning Chen, Kenichi Yoshikawa

JOURNAL OF CHEMICAL PHYSICS 144(20) 205101 2016年5月査読有り
Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex

Ryosuke Imai, Seiji Komeda, Mari Shimura, Sachiko Tamura, Satoshi Matsuyama, Kohei Nishimura, Ryan Rogge, Akihiro Matsunaga, Ichiro Hiratani, Hideaki Takata …

SCIENTIFIC REPORTS 6 4712 2016年4月査読有り
Highly Concentrated Ethanol Solutions: Good Solvents for DNA as Revealed by Single-Molecule Observation

Yuki Oda, Koichiro Sadakane, Yuko Yoshikawa, Tadayuki Imanaka, Kingo Takiguchi, Masahito Hayashi, Takahiro Kenmotsu, Kenichi Yoshikawa

CHEMPHYSCHEM 17(4) 471-473 2016年2月査読有り
Protective effect of ascorbic acid against double-strand breaks in giant DNA: Marked differences among the damage induced by photo-irradiation, gamma-rays and ultrasound

Yue Ma, Naoki Ogawa, Yuko Yoshikawa, Toshiaki Mori, Tadayuki Imanaka, Yoshiaki Watanabe, Kenichi Yoshikawa

CHEMICAL PHYSICS LETTERS 638 205-209 2015年10月査読有り
Structurally Diverse Polyamines: Solid-Phase Synthesis and Interaction with DNA

Naoki Umezawa, Yuhei Horai, Yuki Imamura, Makoto Kawakubo, Mariko Nakahira, Nobuki Kato, Akira Muramatsu, Yuko Yoshikawa, Kenichi Yoshikawa, Tsunehiko Higuchi

CHEMBIOCHEM 16(12) 1811-1819 2015年8月査読有り
Identification of a Novel Aminopropyltransferase Involved in the Synthesis of Branched-Chain Polyamines in Hyperthermophiles

Kazuma Okada, Ryota Hidese, Wakao Fukuda, Masaru Niitsu, Koichi Takao, Yuhei Horai, Naoki Umezawa, Tsunehiko Higuchi, Tairo Oshima, Yuko Yoshikawa …

JOURNAL OF BACTERIOLOGY 196(10) 1866-1876 2014年5月査読有り
Chromatin Compaction Protects Genomic DNA from Radiation Damage

Hideaki Takata, Tomo Hanafusa, Toshiaki Mori, Mari Shimura, Yutaka Iida, Kenichi Ishikawa, Kenichi Yoshikawa, Yuko Yoshikawa, Kazuhiro Maeshima

PLOS ONE 8(10) e75622 2013年10月
Effect of low-frequency ultrasound on double-strand breaks in giant DNA molecules

Kenji Yoshida, Naoki Ogawa, Yukihiro Kagawa, Hiraku Tabata, Yoshiaki Watanabe, Takahiro Kenmotsu, Yuko Yoshikawa, Kenichi Yoshikawa

Applied Physics Letters 103(6) 063705 2013年8月5日査読有り
Structural Change of DNA Induced by Nucleoid Proteins: Growth Phase-Specific Fis and Stationary Phase-Specific Dps

Yuko T. Sato, Shun Watanabe, Takahiro Kenmotsu, Masatoshi Ichikawa, Yuko Yoshikawa, Jun Teramoto, Tadayuki Imanaka, Akira Ishihama, Kenichi Yoshikawa

BIOPHYSICAL JOURNAL 105(4) 1037-1044 2013年8月
Effective chiral discrimination of tetravalent polyamines on the compaction of single DNA molecules

Yuko Yoshikawa, Naoki Umezawa, Yuki Imamura, Toshio Kanbe, Nobuki Kato, Kenichi Yoshikawa, Tadayuki Imanaka, Tsunehiko Higuchi

Angewandte Chemie - International Edition 52(13) 3712-3716 2013年3月25日
Second- and higher-order structural changes of DNA induced by antitumor-active tetrazolato-bridged dinuclear platinum(II) complexes with different types of 5-substituent

Masako Uemura, Yuko Yoshikawa, Kenichi Yoshikawa, Takaji Sato, Yoshiki Mino, Masahiko Chikuma, Seiji Komeda

Journal of Inorganic Biochemistry 127 169-174 2013年査読有り

もっとみる

書籍等出版物

エキスパート生化学「第2版」管理栄養士養成シリーズ

化学同人 2012年3月
栄養・食糧学用語辞典

建帛社 2007年
"Physical Chemistry of DNA-Carrier Complex" in Non-viral Gene Therapy: Gene Design and Delivery

K. Yoshikawa, Y. Yoshikawa

Springer-Verlag, Tokyo 2005年