ISHIBASHI Osamu

J-GLOBAL         Last updated: Jul 25, 2019 at 19:17
 
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Name
ISHIBASHI Osamu
Affiliation
Osaka Prefecture University
Job title
Senior associate professor
ORCID ID
0000-0003-4698-460X

Research Areas

 
 

Academic & Professional Experience

 
Apr 2018
 - 
Today
Nippon Medical School
 

Awards & Honors

 
Oct 2008
Soma Award, Japan Placenta Association
 
Dec 1998
Travel Award, The American Society for Bone and Mineral Research and The International Bone and Mineral Society
Winner: OSAMU ISHIBASHI
 

Published Papers

 
Yamamoto K, Ishibashi O, Sugiura K, Ubatani M, Sakaguchi M, Nakatsuji M, Shimamoto S, Noda M, Uchiyama S, Fukutomi Y, Nishimura S, Inui T
Scientific Reports   9(1) 1503   Feb 2019   [Refereed]
Islam Z, Inui T, Ishibashi O
Biochemical and Biophysical Research Communications      Dec 2018   [Refereed]
Horikawa A, Yoneda T, Yaoita E, Yamaguchi K, Shigenobu S, Kuramochi M, Yamate J, Inui T, Ishibashi O
Journal of biochemistry      Dec 2018   [Refereed]
Jikuzono T, Horikawa A, Ishikawa T, Hirokawa M, Sugitani I, Inui T, Ishibashi O
BMC research notes   11(1) 822   Nov 2018   [Refereed]
Ishibashi O, Akagi I, Ogawa Y, Inui T
Biochemical and biophysical research communications   501(2) 507-513   Jun 2018   [Refereed]
Akagi I, Ishibashi O
Genomics data   12 4-6   Jun 2017   [Refereed]
Ishibashi O., Sakuragi K., Fukutomi Y., Kawakami Y., Kamata Y., Sakurai M., Nakayama S., Uchiyama H., Kobayashi H., Kojima H., Inui T.
ALLERGY   72(6) 918-926   Jun 2017   [Refereed]
Mizoguchi M, Nakatsuji M, Takano J, Ishibashi O, Wada K, Inui T
Journal of pharmaceutical sciences   105(9) 2735-2742   Sep 2016   [Refereed]
Bessho T, Okada T, Kimura C, Shinohara T, Tomiyama A, Imamura A, Kuwamura M, Nishimura K, Fujimori K, Shuto S, Ishibashi O, Kubata BK, Inui T
PLoS neglected tropical diseases   10(1) e0004339   Jan 2016   [Refereed]
Nakatsuji M, Inoue H, Kohno M, Saito M, Tsuge S, Shimizu S, Ishida A, Ishibashi O, Inui T
PloS one   10(11) e0142206   Nov 2015   [Refereed]
Yoneyama K, Ishibashi O, Kawase R, Kurose K, Takeshita T
Anticancer research   35(3) 1401-1410   Mar 2015   [Refereed]
Takahashi T, Zenno S, Ishibashi O, Takizawa T, Saigo K, Ui-Tei K
Nucleic acids research   42(8) 5256-5269   Apr 2014   [Refereed]
Ichiro Akagi, Osamu Ishibashi, Takeshi Matsutani, Nobutoshi Hagiwara, Akihisa Matsuda, Tsutomu Nomura, Hiroshi Makino, Hiroshi Yoshida, Masao Miyashita, Eiji Uchida
Dataset Papers in Science   2014 1   2014   [Refereed]
Ishibashi O, Inui T
Journal of molecular signaling   9 5   2014   [Refereed]
Ohkuchi A, Ishibashi O, Hirashima C, Takahashi K, Matsubara S, Takizawa T, Suzuki M
Hypertension research : official journal of the Japanese Society of Hypertension   35(12) 1152-1158   Dec 2012   [Refereed]
Mase Y, Ishibashi O, Ishikawa T, Takizawa T, Kiguchi K, Ohba T, Katabuchi H, Takeshita T, Takizawa T
Reproductive sciences (Thousand Oaks, Calif.)   19(10) 1030-1040   Oct 2012   [Refereed]
Ishibashi O, Ohkuchi A, Ali MM, Kurashina R, Luo SS, Ishikawa T, Takizawa T, Hirashima C, Takahashi K, Migita M, Ishikawa G, Yoneyama K, Asakura H, Izumi A, Matsubara S, Takeshita T, Takizawa T
Hypertension (Dallas, Tex. : 1979)   59(2) 265-273   Feb 2012   [Refereed]
Ishibashi O, Ali MM, Luo SS, Ohba T, Katabuchi H, Takeshita T, Takizawa T
Science signaling   4(198) ra74   Nov 2011   [Refereed]
Shigehara K, Yokomuro S, Ishibashi O, Mizuguchi Y, Arima Y, Kawahigashi Y, Kanda T, Akagi I, Tajiri T, Yoshida H, Takizawa T, Uchida E
PloS one   6(8) e23584   Aug 2011   [Refereed]
Akagi I, Miyashita M, Ishibashi O, Mishima T, Kikuchi K, Makino H, Nomura T, Hagiwara N, Uchida E, Takizawa T.
Diseases of the Esophagus   24(7) 523-530   2011   [Refereed]
Kanda T, Ishibashi O, Kawahigashi Y, Mishima T, Kosuge T, Mizuguchi Y, Shimizu T, Arima Y, Yokomuro S, Yoshida H, Tajiri T, Uchida E, Takizawa T.
Hepato-Gastroenterology   57(102-103) 1013-1023   Sep 2010   [Refereed]
Ishibashi O, Ikegame M, Takizawa F, Yoshizawa T, Moksed MA, Iizawa F, Mera H, Matsuda A, Kawashima H
Journal of cellular physiology   222(2) 465-473   Feb 2010   [Refereed]
Luo SS, Ishibashi O, Ishikawa G, Ishikawa T, Katayama A, Mishima T, Takizawa T, Shigihara T, Goto T, Izumi A, Ohkuchi A, Matsubara S, Takeshita T, Takizawa T
Biology of reproduction   81(4) 717-729   Oct 2009   [Refereed]
Mera H, Kawashima H, Yoshizawa T, Ishibashi O, Ali MM, Hayami T, Kitahara H, Yamagiwa H, Kondo N, Ogose A, Endo N, Kawashima H
BMC cancer   9 166   May 2009   [Refereed]
Akagi I, Miyashita M, Makino H, Nomura T, Hagiwara N, Takahashi K, Cho K, Mishima T, Ishibashi O, Ushijima T, Takizawa T, Tajiri T.
International Journal of Oncology   34(3) 767-775   Mar 2009   [Refereed]
Kawahigashi Y, Mishima T, Mizuguchi Y, Arima Y, Yokomuro S, Kanda T, Ishibashi O, Yoshida H, Tajiri T, Takizawa T.
Journal of Nippon Medical School   76(4) 188-197   2009   [Refereed]
Mishima T, Takizawa T, Luo SS, Ishibashi O, Kawahigashi Y, Mizuguchi Y, Ishikawa T, Mori M, Kanda T, Goto T, Takizawa T
Reproduction (Cambridge, England)   136(6) 811-822   Dec 2008   [Refereed]
Ali MM, Yoshizawa T, Ishibashi O, Matsuda A, Ikegame M, Shimomura J, Mera H, Nakashima K, Kawashima H
Journal of cell science   120(Pt 15) 2565-2573   Aug 2007   [Refereed]
Ishibashi O, Niwa S, Kadoyama K, Inui T
Life sciences   79(17) 1657-1660   Sep 2006   [Refereed]
Ida-Yonemochi H, Ishibashi O, Sakai H, Saku T
European journal of oral sciences   112(2) 148-155   Apr 2004   [Refereed]
Yoshizawa T, Takizawa F, Iizawa F, Ishibashi O, Kawashima H, Matsuda A, Endo N, Kawashima H.
Molecular and Cellular Biology   24(8) 3460-3472   2004   [Refereed]
Shimomura J, Ishibashi O, Ikegame M, Yoshizawa T, Ejiri S, Noda T, Kawashima H
Journal of cellular physiology   195(3) 488-496   Jun 2003   [Refereed]
Saito Y, Yoshizawa T, Takizawa F, Ikegame M, Ishibashi O, Okuda K, Hara K, Ishibashi K, Obinata M, Kawashima H.
Journal of Cell Science   115(21) 4191-4200   2002   [Refereed]
Ikegame M, Ishibashi O, Yoshizawa T, Shimomura J, Komori T, Ozawa H, Kawashima H.
Journal of Bone and Mineral Research   16(1) 24-32   2001   [Refereed]
Ishibashi O, Inui T, Mori Y, Kurokawa T, Kokubo T, Kumegawa M.
Calcified Tissue International   68(2) 109-116   2001   [Refereed]
Ishibashi O, Kawashima H.
Biochimica et Biophysica Acta - Gene Structure and Expression   1519(3) 223-229   2001   [Refereed]
Ishibashi O, Yamagishi T, Hanada K, Kawashima H.
Biochemical and Biophysical Research Communications   289(3) 705-711   2001   [Refereed]
Niwa Satoru, Ishibashi Osamu, Inui Takashi
Life Sciences   70(3) 315-324   2001   [Refereed]
Cloning and characterization of the functional promoter of mouse estrogen receptor beta gene(共著)
Biochimica et Biophysica Acta   1519 223-229   2001
Quantification of the Expression Levels of Lysosomal Cysteine Proteinases in Purified Human Osteoclastic Cells by Competitive RT-PCR.(共著)
Calcified Tissue International   68(2) 109-116   2001
Kawashima H, Ikegame M, Shimomura J, Ishibashi O, Komori T, Noda T, Ozawa H.
Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology   7(2)    2000   [Refereed]
Ishibashi O.
Journal of Biochemistry, Molecular Biology and Biophysics   2(4) 259-264   1999   [Refereed]
Ishibashi O, Mori Y, Kurokawa T, Kumegawa M.
Cancer Biochemistry Biophysics   17(1-2) 69-78   1999   [Refereed]
Breast Cancer cells express cathepsins B and L but not cathepsins K or H(共著)
Cancer Biochemistry Biophysics   17 69-78   1999
Increased expression of Iysosomal cysteine proteinases with differentiation of HL-60 and THP-1 towards macrophage-like cells induced by phorbol ester
Journal of Biochemistry, Molecular Biology and Biophysics   2 259-264   1999
INUI T, ISHIBASHI O, ORIGANE Y, FUJIMORI K, KOKUBO T, NAKAJIMA M
Biochemical and Biophysical Research Communication   258(1) 173-178   1999   [Refereed]
SAITOH E, MINAGUCHI K, ISHIBASHI O
Archives of Biochemistry and Biophysics   352(2) 199-206   Apr 1998
Two variants of cystatin SA encoded by two alleles at the CST2 locus of the type 2 human cystatin gene family were expressed in Escherichia coli. One, termed cystatin SA1, is identical to cystatin SA [S. Isemura, E. Saitoh, and K. Sanada J. Bioche...
INUI T, ISHIBASHI O, INAOKA T, ORIGANE Y, KUMEGAWA M, KOKUBO T, YAMAMURA T
J. Biol. Chem.   272(13) 8109-8112   Mar 1997
Cathepsin K is a recently identified cysteine protease which is abundantly and selectively expressed in osteoclasts. To evaluate the contribution of cathepsin K to bone resorption processes, we investigated the effect of cathepsin K antisense phos...
LITTLEWOOD‐EVANS A, KOKUBO T, ISHIBASHI O, INAOKA T, WLODARSKI B, GALLAGHER J A, BILBE G
Bone   20(2) 81-86   Feb 1997
We have recently cloned cathepsin K from a human bone cDNA library. Since cathepsins are proposed to be involved in the degradation of mineralized bone matrix, we have investigated, by in situ hybridization and immunocytochemistry, the expression ...
ISHIBASHI O
Journal of Biochemical and Biophysical Methods   35(3) 203-207   1997   [Refereed]
INAOKA T, BILBE G, ISHIBASHI O, TEZUKA K, KUMEGAWA M, KOKUBO T
Biochem Biophys Res Commun   206(1) 89-96   Jan 1995
We have previously cloned a rabbit cDNA clone (OC-2) from an osteoclast cDNA library by the differential screening. OC-2 was found to encode a novel cysteine proteinase, tentatively called cathepsin K, which is predominantly expressed in osteoclas...
ISHIBASHI O, SHISHIDO K
Current Genetics   25(1) 30-33   Jan 1994
It was shown by a plasmid exchange procedure that the Ras-encoding cDNA of the basidiomycete Lentinus edodes (named Leras cDNA) can functionally replace its homolog genes (ScRAS1 and ScRAS2) in the yeast Saccharomyces cerevisiae to maintain the vi...
ISHIBASHI O, SHISHIDO K
Gene   125(2) 233-234   Mar 1993
The basidiomycete Lentinus edodes (Le.) ras gene (or its cDNA clone) [Hori et al., Gene 105 (1991) 91-96] was utilized to identify and clone the corresponding gene (Cc.ras)-containing genomic fragment from the basidiomycete, Coprinus cinereus. Cc....

Misc

 
Mishima T, Akagi I, Miyashita M, Ishibashi O, Mizuguchi Y, Tajiri T, Takizawa T.
Journal of Nippon Medical School   76(1) 43   Feb 2009   [Refereed]
Kokubo T, Ishibashi O, Kumegawa M.
Advances in Organ Biology   5(C) 359-370   1998   [Refereed]

Books etc

 
Osteoporosis Navigator
ISHIBASHI Osamu (Part:Joint Work)
Medical Review   2001   
Osteoclast proteases(共著)
JCI Press   

Conference Activities & Talks

 
A novel drug delivery system for poorly water-soluble anti-tumor drug SN-38 utilizing intravital transporter protein
Nakatsuji Masatoshi, Inoue Haruka, Kohno Masaki, Saito Mayu, Tsuge Syogo, Shimizu Shota, Ishibashi Osamu, Inui Takashi
PROTEIN SCIENCE   Oct 2015   
The Comprehensive Analysis of PI3K/AKT Pathway and miRNAs in Esophageal Squamous Cell Carcinoma
Akagi Ichiro, Matsutani Takeshi, Ishibashi Osamu, Makino Hiroshi, Yoshida Hiroshi, Nomura Tsutomu, Hagiwara Nobutoshi, Maruyama Hiroshi, Yokoyama Tadashi, Hirakata Atsushi, Ueda Junji, Miyashita Masao, Uchida Eiji
AMERICAN JOURNAL OF GASTROENTEROLOGY   Oct 2015   
Placenta-specific miRNAs derived from the Chromosome 19 miRNA Cluster in Normal Pregnancy and Preeclampsia [Invited]
ISHIBASHI Osamu
International Federation of Placenta Association Meeting 2010   22 Oct 2010   
Relationship between altered expression levels of MIR21, MIR143, MIR145, and MIR205 and clinicopathologic features of esophageal squamous cell carcinoma(ESCC)
Makino Hiroshi, Ucida Eiji, Akagi Ichiro, Miyashita Masao, Nomura Tsutomu, Hagiwara Nobutoshi, Ishibashi Osamu, Takizawa Toshihiro
CANCER RESEARCH   Apr 2010   
Tensile Stress Induces Bone Morphogenetic Protein 4 in Preosteoblastic and Fibroblastic Cells, Which Later Differentiate into Osteoblasts Leading to Osteogenesis in the Mouse Calvariae in Organ Culture(共著)
Journal of Bone and Mineral Research   2001   
Cathepsin K expressed at a high level in osteoclasts shows strong collagen olytic activity
The 18th Annval Meeting of American Society for Bone and Mineral Research   1996   
A novel cysteine proteinase localized at ruffled border : cathepsin K
The 17th Annual Meeting of American Society for Bone and Mineral Research   1995   

Research Grants & Projects

 
JSPS: KAKENHI
Project Year: Apr 2019 - Mar 2022    Investigator(s): ISHIBASHI Osamu
Functional and Kinetic analyses of microRNAs
Grant-in-Aid for Scientific Research
Project Year: 2007 - 2012
Development of biomarkers for the selection of ova for IVF - from the viewpoints of microRNA and local factors
Grant-in-Aid for Scientific Research
Project Year: 2007 - 2012
Regulational factors for osteoblast differentiation and mineralization
Project Year: 1995 - 2010