Tomoko Mizote - My portal

Profile Information

Affiliation: Professor, Faculty of Nursing and Human Nutrition, Yamaguchi Prefectural University

Degree: (BLANK)(Yamaguchi University)

J-GLOBAL ID: 200901025191714610
researchmap Member ID: 1000223447

External link: http://yamaguchi-pu.ac.jp

Research Interests

Research Areas

Research History

2007 - Present

- 山口県立大学教授

Education

Papers

Identification of self-growth-inhibiting compounds lauric acid and 7-(Z)-tetradecenoic acid from Helicobacter pylori

Shinpei Yamashita, Masayuki Igarashi, Chigusa Hayashi, Tetsuo Shitara, Akio Nomoto, Tomoko Mizote, Masakatsu Shibasaki

MICROBIOLOGY-SGM, 161 1231-1239, Jun, 2015 Peer-reviewed
Experimental Measurement of the Effects of the First-Year Experience Utilizing Data and Text Mining Technology

Ikeda Fumiko, AzetsuTadahiro, Hirose Haruji, MIZOTE Tomoko

33(1) 137-145, 2011 Peer-reviewed
Measurement of the Effects of First-Year Experience Based on an Education for Sustainable Developement Program

Ikeda Humiko, Kohashi Keisuke, Matsuo Hiroshi Hirose, Haruji MIZOTE Tomoko

3(1) 67-74, 2010 Peer-reviewed
Functional characterization and mutagenesis of the proposed behavioral sensor TlpD of Helicobacter pylori

Tobias Schweinitzer, Tomoko Mizote, Naohiro Ishikawa, Alexey Dudnik, Sakiko Inatsu, Soeren Schreiber, Sebastian Suerbaum, Shin-Ichi Aizawa, Christine Josenhans

JOURNAL OF BACTERIOLOGY, 190(9) 3244-3255, May, 2008
Functional characterization and mutagenesis of the proposed behavioral sensor TlpD of Helicobacter pylori

Tobias Schweinitzer, Tomoko Mizote, Naohiro Ishikawa, Alexey Dudnik, Sakiko Inatsu, Soeren Schreiber, Sebastian Suerbaum, Shin-Ichi Aizawa, Christine Josenhans

JOURNAL OF BACTERIOLOGY, 190(9) 3244-3255, May, 2008 Peer-reviewed
Possible involvement of put A gene in Helicobacter pylori colonization in the stomach and motility

Kazuhiko Nakajima, Sakiko Natsu, Tomoko Mizote, Yoko Nagata, Kazue Aoyania, Yoshihiro Fukuda, Kumiko Nagata

BIOMEDICAL RESEARCH-TOKYO, 29(1) 9-18, Feb, 2008 Peer-reviewed
Herbtaxis of Helicobacter pylori and effects of herbs on its behavior.

MIZOTE Tomoko, Ishikawa Naohiro, Hitomi Eri, Yamamoto Nobuhisa, Mochizuki Satoshi

1 17-23, 2008
Food conctituents enhance urease activity in Helicobacter pylori.

MIZOTE Tomoko, Inatsu Sakiko, Ehara Keiko

31 13-19, 2006
Biosynthesis of hydroxymethylpyrimidine pyrophosphate in Saccharomyces cerevisiae

Y Kawasaki, M Onozuka, T Mizote, K Nosaka

CURRENT GENETICS, 47(3) 156-162, Mar, 2005
A regulator gene for acetate utilisation from Neurospora crassa

M Bibbins, VF Crepin, NJ Cummings, T Mizote, K Baker, KH Mellits, IF Connerton

MOLECULAR GENETICS AND GENOMICS, 267(4) 498-505, Jun, 2002
Cloning and characterization of the thiD/J gene of Escherichia coli encoding a thiamin-synthesizing bifunctional enzyme, hydroxymethylpyrimidine kinase phosphomethylpyrimidine kinase

T Mizote, M Tsuda, DDS Smith, H Nakayama, T Nakazawa

MICROBIOLOGY-UK, 145 495-501, Feb, 1999 Peer-reviewed
Promoter analysis of the acetate-inducible isocitrate lyase gene (acu-3) from Neurospora crassa

M Bibbins, PJ Sheffield, LDS Gainey, T Mizote, IF Connerton

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1442(2-3) 320-325, Nov, 1998 Peer-reviewed
Chemotaxis of Helicobacter pylori: A urease-independent response

H Yoshiyama, T Mizote, H Nakamura, K Okita, T Nakazawa

JOURNAL OF GASTROENTEROLOGY, 33 1-5, Nov, 1998 Peer-reviewed
Urease plays an important role in the chemotactic motility of Helicobacter pylori in a viscous environment

H Nakamura, H Yoshiyama, H Takeuchi, T Mizote, K Okita, T Nakazawa

INFECTION AND IMMUNITY, 66(10) 4832-4837, Oct, 1998 Peer-reviewed
Urease-independent chemotaxis response of Helicobacter pylori to urea, urea-inhibitors and Sodium bcarbonate.

Tomoko Mizote, H. Yoshiyama, T. Nakazawa

Infec. Immun., 65 1519-1521, 1997 Peer-reviewed
The thiJ locus and its relation to phosphorylation of hydroxymethylpyrimidine in Escherichia coli

T Mizote, M Tsuda, T Nakazawa, H Nakayama

MICROBIOLOGY-UK, 142 2969-2974, Oct, 1996 Peer-reviewed
Gel mobility shift scanning of the acetate inducible proteins from Neurospora crassa reveals a common co-inducible DNA-binding proteins.

MIZOTE tomoko, M. Bibbins, P.J.Shefield, I.F.Connerton

250(4) 421-427, 1996 Peer-reviewed

Misc.

香辛料からみた食習慣のH.pylori病原因子に及ぼす影響

浦上食品食文化振興財団, 70-79, 2002
Effect of Spices in Diet towords Pathogeneses of H.pylori.

Urakami Fouddation, 10, 70-79, 2002
食物中の胃疾患原因菌ヘリコバクター・ピロリ感染予防に関与する因子の解明

アサヒビール学術振興財団, 12, 61-68, 2001
Iwestigation of prevention from Heliobactor pylori infection throuph dietary elements.

Asahi Beer Foundation, 12, 61-68, 2001
Cloning and characterization of the ┣DBthiD(/)-┫DB/┣DBJ(/)-┫DB gene of Escherichia coli encoding a thiamly-Synfliosizing bifunctional enzyme,hidroxymetlylpyrimdme kinase/phosphometlylpyrimidine kinase.

Microbiology, 145 495-501, 1999
Chemotaxis of Helicobacter pylori: A urease-independent response

H Yoshiyama, T Mizote, H Nakamura, K Okita, T Nakazawa

JOURNAL OF GASTROENTEROLOGY, 33(Suppl.) 1-5, Nov, 1998
Promoter analysis of the acetate-inducible isocitrate lyase gene (┣DBacu-3(/)-┫DB) from ┣DBNeurospora(/)-┫DB ┣DBcrassa(/)-┫DB.

Biochim. Biophys. Acta, 1442 320-325, 1998
Urea plays an important role in the chemotactic motility of ┣DBHelicobacter(/)-┫DB ┣DBpylori(/)-┫DB in a Uiscous environment

Infect. Immun., 66 4832-4837, 1998
Urease-Independent Chemotactic Responses of Helicobacter pylori to Urea, Urease Inhibitors and Sodium Bicarbonate

Intection and Immunity, 65(4) 1519, 1997
The thiJ locus and its relation to phosphorylation of hydroxymethylpyrimidine in Escherichia coli

T Mizote, M Tsuda, T Nakazawa, H Nakayama

MICROBIOLOGY-UK, 142 2969-2974, Oct, 1996
Gel mobility shift scanning of the acetate-inducible promoters from Neurospura crassa reveals a common co-inducible DNA-binding protein

Mol. Gen. Genet., 250(4) 421-427, 1996
Essential role of Helicobacter pylori urease in gastric colonization : definite proot using a mease-negative mntant constructed by gene replacement

European Journal of Gastroenterology & Hepatology, 6(1) 549, 1994
Purification and properties of hydroxymethylpyrlmidine kinase from Escherichia coli

Biochim. Biophys. Acta, 991 109, 1989
The thiM Locus and its Relation to phosphorylation of Hydroxyethy Hbiazole in Escherichia coli

J. Bacteriology, 171 3228, 1989

Books and Other Publications

感染と生体防御

溝手朝子 (Role: Joint author)

2018

Presentations

山口県内の市販及び食鳥処理場の鶏肉から分離されたカンピロバクターの薬剤感受性について

溝手朝子

第114回日本食品衛生学会, Nov 15, 2018
食鳥肉から分離されたCampylobacterの薬剤耐性獲得状況について

溝手朝子

第39回日本食品微生物学会, Sep 27, 2018
Characterization of the growth influence factor in C. jejuni.

溝手朝子

第91回日本細菌学会総会, Mar, 2018
H. pyloriの自己増殖制御物質が細胞分裂に関与する遺伝子(ftsZ)の発現に及ぼす影響

溝手朝子

第70回日本細菌学会中国四国支部総会, Oct 14, 2017
C. jejuniの低コスト簡便スクリーニング法の検討

溝手朝子

第38回日本食品微生物学会学術総会, Oct 6, 2017
Investigation of the VNC-like cells inducing materials in C. jejuni.

溝手朝子

第90回日本細菌学会, Mar 19, 2017
市販鶏肉の細菌汚染状況とカンピロバクターの増殖制御因子について

溝手朝子

第111回日本食品衛生学会, May 14, 2016
ピロリ菌感染はEBウィルスの胃上皮細胞における感染増殖を協調的に活性化する

溝手朝子

第89回日本細菌学会（, Mar, 2016
Campylobacter jejuniの自己凝集因子について

溝手朝子

第89回日本細菌学会, Mar, 2016
ピロリ菌は胃上皮細胞に感染したEBウィルスの増殖を促す

溝手朝子

第69回日本細菌学会中国四国支部総会, Oct, 2015
Identification of self-growth inhibiting compounds from H. pylori.

溝手朝子

第88回日本細菌学会, Mar, 2015
山口県下で市販されている有機肥料中の薬剤耐性菌保有状況について

溝手朝子

第107回日本食品衛生学会, May, 2014
Helicobacter pylori培養液中に分泌される増殖阻害物質の精製

溝手朝子

第87回日本細菌学会, Mar, 2014

Teaching Experience

Professional Memberships

Works

Wuerzburg Univ.

Research Projects

肉用鶏農場における食中毒菌（カンピロバクター及びサルモネラ）の汚染リスクを低減するための研究

平成３０年度戦略的プロジェクト研究推進事業委託事業「有害化学物質・微生物の動態解明によるリスク管理技術の開発」, 農林水産省, Sep, 2018 - Mar, 2023

豊福肇
健常者の表在性常在細菌の薬剤耐性能に関する研究

その他の研究制度, 2010 - 2012
ヘリコバクター・ピロリのウレアーゼ遺伝子発現と食環境因子

2003 - 2006
Chemotaxis of H.pylori

1997 - 2005
大腸菌のTPP生合成経路の分子遺伝学的解析

1998 - 1999
Molecular genetical approach to imestigate biosynthetic pathway of TPP in Escherichia coli.

1988 - 1999
ヘリコバクター・ピロリの走化性に関する研究

1997
H. pyloriのウレアーゼ活性抑制食品成分に関する研究
Research on Inhibition of Urease activity in H. pylori by Food components.
Research on Mechanism of Gastric Crisis by H. pylori Infection.