J-GLOBAL         Last updated: Jun 25, 2019 at 15:38
Tohoku Medical and Pharmaceutical University
Faculty of Pharmaceutical Sciences, Department of Pharmaceutical Science, Department of Pharmacology
Job title
Associate Professor
Master(Pharmacy)(Tohoku Pharmaceutical University), Doctor(Pharmacy)(Tohoku Pharmaceutical University)

Research Areas


Academic & Professional Experience

Research Associate, Tohoku Phamaceutical


Graduate School, Division of Pharmaceutical Sciences, Tohoku Pharmaceutical University
Faculty of Pharmaceutical Science, Tohoku Pharmaceutical University

Awards & Honors

Poster Investigator Award, NRF-JSPS Asian Science Seminar 2012
The Pharmaceutical Soc. of Japan northeast branch encouraging prize.

Published Papers

Takahashi K, Nakagawasai O, Nemoto W, Nakajima T, Arai Y, Hisamitsu T, Tan-No K
Psychopharmacology   233(7) 1311-1322   Apr 2016   [Refereed]
Ogata Y, Nemoto W, Nakagawasai O, Yamagata R, Tadano T, Tan-No K
Molecular pharmacology   90(3) 205-213   Sep 2016   [Refereed]
Nakagawasai O, Nemoto W, Onogi H, Moriya T, Lin JR, Odaira T, Yaoita F, Ogawa T, Ohta K, Endo Y, Tan-No K
Behavioural brain research   297 315-322   Jan 2016   [Refereed]
Nemoto W, Yamada K, Ogata Y, Nakagawasai O, Onodera K, Sakurai H, Tan-No K
Journal of pharmacological sciences   131(4) 275-278   Aug 2016   [Refereed]
Nemoto W, Ogata Y, Nakagawasai O, Yaoita F, Tadano T, Tan-No K
Neuropharmacology   99 221-231   Dec 2015   [Refereed]


Kohei Takahashi, Osamu Nakagawasai, Wakana Sakuma, Wataru Nemoto, Takayo Odaira, Jia Rong Lin, Hiroshi Onogi, Lalit K. Srivastava, Koichi Tan-No
Neuropharmacology   150 1-14   May 2019
© 2019 Elsevier Ltd Methylazoxymethanol (MAM)-treated pregnant rat at gestation day (GD) 17 has been shown to be a valuable developmental animal model for schizophrenia. Yet, this model remains to be established in mice. In the present study, we e...
Takayo Odaira, Osamu Nakagawasai, Kohei Takahashi, Wataru Nemoto, Wakana Sakuma, Jia Rong Lin, Koichi Tan-No
Neuropharmacology   150 121-133   May 2019
© 2019 Elsevier Ltd Adenosine monophosphate-activated protein kinase (AMPK) is critical for whole-body energy metabolism regulation. Recent studies have suggested that physical exercise ameliorates depressive-like behaviors via AMPK activation; ho...
Yoshiki Ogata, Wataru Nemoto, Ryota Yamagata, Osamu Nakagawasai, Shuji Shimoyama, Tomonori Furukawa, Shinya Ueno, Koichi Tan-No
European Journal of Pain (United Kingdom)   23 739-749   Apr 2019
© 2018 European Pain Federation - EFIC® Background: We have recently reported that the spinal angiotensin (Ang) converting enzyme (ACE)/Ang II/AT1 receptor axis and downstream p38 MAPK phosphorylation are activated in streptozotocin (STZ)-induced ...
Ryota Yamagata, Wataru Nemoto, Osamu Nakagawasai, Wan Yi Hung, Kazuhiro Shima, Yasuo Endo, Koichi Tan-No
Naunyn-Schmiedeberg's Archives of Pharmacology   392 349-357   Mar 2019
© 2018, Springer-Verlag GmbH Germany, part of Springer Nature. Etidronate is widely used as a therapeutic agent for osteoporosis. We have recently shown that intrathecal administration of etidronate into mice produces an analgesic effect against t...
Wataru Nemoto, Kotaro Yamada, Osamu Nakagawasai, Yoshiki Ogata, Masato Chiba, Ryota Yamagata, Hidetomo Sakurai, Koichi Tan-No
Journal of Pharmacological Sciences   137 403-406   Aug 2018
© 2018 The Authors We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 m...

Books etc

In: Methamphetamines: Abuse, Health Effects and Treatment Options
NAKAGAWASAI Osamu (Part:Joint Work)
Nova Science Publishers   2012   
Monoamine Oxidases: Molecular, Pharmacological and Neurotoxicological Aspects
NAKAGAWASAI Osamu (Part:Joint Work)
Elsevier Science Publishers B.V.   2004   
Advances in Neurobehavioral Pharmacology -"Antidementia"-
J. R. Prous S. A. Publishers   1997   
The effect of ginkgo biloba extract (GbE) on impairment of memory and learning
Elsevier Science Frontiers of the mecharisms of memory and dementia   2000   
Involvement of Histamine Receptors in P-Hydroxyamphetamine-Induced Head-Twitch Behavior
Elsevier Science, Histamine Research in the New Millennium   2001   

Research Grants & Projects

The mechanism of learning and memory impairment in animals
Project Year: 1995   
The mechanism of abnormal behaviors in schizophrenia animal models
Project Year: 2004