OSAWA Haruhiko

J-GLOBAL         Last updated: Jan 6, 2019 at 11:51
 
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Name
OSAWA Haruhiko
Affiliation
Ehime University
Section
Graduate School of MedicineDoctor Course
Job title
Professor,Director of the Division

Research Areas

 
 

Published Papers

 
Kawabata Y, Nishida N, Awata T, Kawasaki E, Imagawa A, Shimada A, Osawa H, Tanaka S, Takahashi K, Nagata M, Yasuda H, Uchigata Y, Kajio H, Makino H, Yasuda K, Kobayashi T, Hanafusa T, Tokunaga K, Ikegami H
Diabetes      Dec 2018   [Refereed]
Tokunaga A, Imagawa A, Nishio H, Hayata S, Shimomura I, Abiru N, Awata T, Ikegami H, Uchigata Y, Oikawa Y, Osawa H, Kajio H, Kawasaki E, Kawabata Y, Kozawa J, Shimada A, Takahashi K, Tanaka S, Chujo D, Fukui T, Miura J, Yasuda K, Yasuda H, Kobayashi T, Hanafusa T, consultation of Japan Diabetes Society Committee on Fulminant Type 1 Diabetes Mellitus Research.
Diabetology international   9(4) 257-265   Oct 2018   [Refereed]
Saito I, Takata Y, Maruyama K, Eguchi E, Kato T, Shirahama R, Tomooka K, Kawamura R, Sano M, Tabara Y, Osawa H, Tanigawa T
American journal of hypertension   31(10) 1120-1126   Sep 2018   [Refereed]
Murao S, Takata Y, Yasuda M, Osawa H, Kohi F
American journal of hypertension   31(8) 876-885   Jul 2018   [Refereed]
Noumi Y, Kawamura R, Tabara Y, Maruyama K, Takata Y, Nishida W, Okamoto A, Nishimiya T, Onuma H, Saito I, Tanigawa T, Osawa H
Clinical endocrinology   88(1) 51-57   Jan 2018   [Refereed]
Morikawa S, Kaneko N, Okumura C, Taguchi H, Kurata M, Yamamoto T, Osawa H, Nakanishi A, Zako T, Masumoto J
International journal of immunopathology and pharmacology   32 2058738418788749   Jan 2018   [Refereed]
Saito I, Maruyama K, Eguchi E, Kato T, Kawamura R, Takata Y, Onuma H, Osawa H, Tanigawa T
Circulation journal : official journal of the Japanese Circulation Society   81(10) 1447-1453   Sep 2017   [Refereed]
Osawa H
Diabetology international   8(3) 243   Aug 2017   [Refereed]
Oikawa Y, Shimada A, Awata T, Fukui T, Ikegami H, Imagawa A, Kajio H, Kawabata Y, Kawasaki E, Miura J, Osawa H, Takahashi K, Tanaka S, Uchigata Y, Yasuda H, Yasuda K, Hanafusa T, Kobayashi T, Research Committee on Type 1 Diabetes of the Japan Diabetes Society.
Diabetology international   8(3) 306-315   Aug 2017   [Refereed]
Onuma H, Tabara Y, Kawamura R, Ohashi J, Nishida W, Takata Y, Ochi M, Nishimiya T, Ohyagi Y, Kawamoto R, Kohara K, Miki T, Osawa H
The Journal of clinical endocrinology and metabolism   102(3) 884-892   Mar 2017   [Refereed]
Kawamura R, Tabara Y, Tsukada A, Igase M, Ohashi J, Yamada R, Takata Y, Kawamoto R, Saito I, Onuma H, Tanigawa T, Yamada K, Kato N, Ohyagi Y, Miki T, Kohara K, Osawa H
Physiological genomics   48(11) 874-881   Nov 2016   [Refereed]
Baden MY, Imagawa A, Iwahashi H, Shimomura I, Awata T, Ikegami H, Uchigata Y, Osawa H, Kajio H, Kawasaki E, Kawabata Y, Shimada A, Takahashi K, Tanaka S, Yasuda K, Yasuda H, Kobayashi T, Hanafusa T
Diabetology international   7(3) 281-288   Sep 2016   [Refereed]
Hamada J, Onuma H, Ochi F, Hirai H, Takemoto K, Miyoshi A, Matsushita M, Kadota Y, Ohashi J, Kawamura R, Takata Y, Nishida W, Hashida S, Ishii E, Osawa H
Journal of diabetes investigation   7(3) 312-323   May 2016   [Refereed]
Saito I, Hitsumoto S, Maruyama K, Eguchi E, Kato T, Okamoto A, Kawamura R, Takata Y, Nishida W, Nishimiya T, Onuma H, Osawa H, Tanigawa T
Atherosclerosis   244 79-85   Jan 2016   [Refereed]
Yasui J, Kawasaki E, Tanaka S, Awata T, Ikegami H, Imagawa A, Uchigata Y, Osawa H, Kajio H, Kawabata Y, Shimada A, Takahashi K, Yasuda K, Yasuda H, Hanafusa T, Kobayashi T, Japan Diabetes Society Committee on Type 1 Diabetes Mellitus Research.
PloS one   11(5) e0155643   2016   [Refereed]
Kawabe K, Ochi S, Yoshino Y, Mori Y, Onuma H, Osawa H, Hosoda Y, Ueno S
Therapeutic advances in psychopharmacology   5(5) 271-277   Oct 2015   [Refereed]
Higuchi K, Saito I, Maruyama K, Eguchi E, Mori H, Tanno S, Sakurai S, Kishida T, Nishida W, Osawa H, Tanigawa T
Nutrition (Burbank, Los Angeles County, Calif.)   31(7-8) 975-980   Jul 2015   [Refereed]
Maruyama K, Nishioka S, Miyoshi N, Higuchi K, Mori H, Tanno S, Tomooka K, Eguchi E, Furukawa S, Saito I, Sakurai S, Nishida W, Osawa H, Tanigawa T
Obesity (Silver Spring, Md.)   23(6) 1296-1302   Jun 2015   [Refereed]
Miyamoto H, Suzuki T, Murakami S, Fukuoka M, Tanaka Y, Kondo T, Nishimiya T, Suemori K, Tauchi H, Osawa H
Journal of medical microbiology   64(Pt 4) 369-374   Apr 2015   [Refereed]
Hwang JY, Sim X, Wu Y, Liang J, Tabara Y, Hu C, Hara K, Tam CH, Cai Q, Zhao Q, Jee S, Takeuchi F, Go MJ, Ong RT, Ohkubo T, Kim YJ, Zhang R, Yamauchi T, So WY, Long J, Gu D, Lee NR, Kim S, Katsuya T, Oh JH, Liu J, Umemura S, Kim YJ, Jiang F, Maeda S, Chan JC, Lu W, Hixson JE, Adair LS, Jung KJ, Nabika T, Bae JB, Lee MH, Seielstad M, Young TL, Teo YY, Kita Y, Takashima N, Osawa H, Lee SH, Shin MH, Shin DH, Choi BY, Shi J, Gao YT, Xiang YB, Zheng W, Kato N, Yoon M, He J, Shu XO, Ma RC, Kadowaki T, Jia W, Miki T, Qi L, Tai ES, Mohlke KL, Han BG, Cho YS, Kim BJ
Diabetes   64(1) 291-298   Jan 2015   [Refereed]
Saito I, Hitsumoto S, Maruyama K, Nishida W, Eguchi E, Kato T, Kawamura R, Takata Y, Onuma H, Osawa H, Tanigawa T
Journal of epidemiology   25(9) 583-591   2015   [Refereed]
Harase T, Nishida W, Hamakawa T, Hino S, Shigematsu K, Kobayashi S, Sako H, Ito S, Murakami H, Nishida K, Inoue H, Fujisawa M, Yoshizu H, Kawamura R, Takata Y, Onuma H, Shimizu K, Hamakawa H, Osawa H
BMJ open diabetes research & care   3(1) e000151   2015   [Refereed]
Tanno S, Tanigawa T, Saito I, Nishida W, Maruyama K, Eguchi E, Sakurai S, Osawa H, Punjabi NM
Sleep medicine   15(10) 1212-1218   Oct 2014   [Refereed]
Nishida W, Nagata M, Imagawa A, Hanafusa T, Ohashi J, Takahashi K, Suehiro T, Yamada Y, Chujo D, Kawasaki E, Kawamura R, Onuma H, Osawa H, Makino H
The Journal of clinical endocrinology and metabolism   99(9) E1793-7   Sep 2014   [Refereed]
Uetani E, Tabara Y, Kawamoto R, Onuma H, Kohara K, Osawa H, Miki T
Diabetes care   37(2) 396-401   Feb 2014   [Refereed]
Wu Y, Gao H, Li H, Tabara Y, Nakatochi M, Chiu YF, Park EJ, Wen W, Adair LS, Borja JB, Cai Q, Chang YC, Chen P, Croteau-Chonka DC, Fogarty MP, Gan W, He CT, Hsiung CA, Hwu CM, Ichihara S, Igase M, Jo J, Kato N, Kawamoto R, Kuzawa CW, Lee JJ, Liu J, Lu L, McDade TW, Osawa H, Sheu WH, Teo Y, Vadlamudi S, Van Dam RM, Wang Y, Xiang YB, Yamamoto K, Ye X, Young TL, Zheng W, Zhu J, Shu XO, Shin C, Jee SH, Chuang LM, Miki T, Yokota M, Lin X, Mohlke KL, Tai ES
Human molecular genetics   23(4) 1108-1119   Feb 2014   [Refereed]
Kawasaki E, Maruyama T, Imagawa A, Awata T, Ikegami H, Uchigata Y, Osawa H, Kawabata Y, Kobayashi T, Shimada A, Shimizu I, Takahashi K, Nagata M, Makino H, Hanafusa T
Journal of diabetes investigation   5(1) 115-118   Feb 2014   [Refereed]
Gao H, Kim YM, Chen P, Igase M, Kawamoto R, Kim MK, Kohara K, Lee J, Miki T, Ong RT, Onuma H, Osawa H, Sim X, Teo YY, Tabara Y, Tai ES, van Dam RM
Diabetes   62(12) 4277-4283   Dec 2013   [Refereed]
Onuma H, Tabara Y, Kawamura R, Ohashi J, Nishida W, Takata Y, Ochi M, Nishimiya T, Kawamoto R, Kohara K, Miki T, Osawa H
Diabetes   62(2) 649-652   Feb 2013   [Refereed]
Tabara Y, Igase M, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Okada Y, Hitsumoto S, Onuma H, Nagai T, Takata Y, Uetani E, Takita R, Kido T, Ochi N, Osawa H, Tanigawa T, Miki T
Clinical hemorheology and microcirculation   55(3) 297-311   2013   [Refereed]
Onuma H, Tohyama M, Imagawa A, Hanafusa T, Kobayashi T, Kano Y, Ohashi J, Hashimoto K, Osawa H, Makino H, Japan Diabetes Society Committee on Type 1 Diabetes Mellitus Research., Japanese Dermatological Association.
The Journal of clinical endocrinology and metabolism   97(12) E2277-81   Dec 2012   [Refereed]
Imagawa A, Hanafusa T, Awata T, Ikegami H, Uchigata Y, Osawa H, Kawasaki E, Kawabata Y, Kobayashi T, Shimada A, Shimizu I, Takahashi K, Nagata M, Makino H, Maruyama T
Journal of diabetes investigation   3(6) 536-539   Dec 2012   [Refereed]
Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Makino H, Kohara K, Miki T
Metabolism: clinical and experimental   60(11) 1634-1640   Nov 2011   [Refereed]
Tabara Y, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Onuma H, Takata Y, Osawa H, Miki T, Tanigawa T
Journal of hypertension   29(10) 1948-1954   Oct 2011   [Refereed]
Kawamura R, Doi Y, Osawa H, Ninomiya T, Hata J, Yonemoto K, Tanizaki Y, Iida M, Makino H, Kiyohara Y
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   25(10) 3236-3240   Oct 2010   [Refereed]
Onuma H, Tabara Y, Kawamoto R, Shimizu I, Kawamura R, Takata Y, Nishida W, Ohashi J, Miki T, Kohara K, Makino H, Osawa H
Journal of human genetics   55(9) 600-604   Sep 2010   [Refereed]
Osawa H, Tabara Y, Ohashi J, Kawamura R, Onuma H, Makino H
Diabetologia   53(4) 795-797   Apr 2010   [Refereed]
Onuma H, Tabara Y, Kawamura R, Tanaka T, Ohashi J, Nishida W, Takata Y, Ochi M, Yamada K, Kawamoto R, Kohara K, Miki T, Makino H, Osawa H
PloS one   5(3) e9718   Mar 2010   [Refereed]
Okamoto K, Iwasaki N, Nishimura C, Doi K, Noiri E, Nakamura S, Takizawa M, Ogata M, Fujimaki R, Grarup N, Pisinger C, Borch-Johnsen K, Lauritzen T, Sandbaek A, Hansen T, Yasuda K, Osawa H, Nanjo K, Kadowaki T, Kasuga M, Pedersen O, Fujita T, Kamatani N, Iwamoto Y, Tokunaga K
American journal of human genetics   86(1) 54-64   Jan 2010   [Refereed]
Osawa H, Doi Y, Makino H, Ninomiya T, Yonemoto K, Kawamura R, Hata J, Tanizaki Y, Iida M, Kiyohara Y
Cardiovascular diabetology   8 60   Nov 2009   [Refereed]
Osawa H, Tabara Y, Kawamoto R, Ohashi J, Ochi M, Onuma H, Nishida W, Yamada K, Nakura J, Miki T, Makino H, Kohara K
Clinical endocrinology   71(3) 341-345   Sep 2009   [Refereed]
Miyake K, Yang W, Hara K, Yasuda K, Horikawa Y, Osawa H, Furuta H, Ng MC, Hirota Y, Mori H, Ido K, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Wang HY, Tanahashi T, Nakamura N, Takeda J, Maeda E, Yamamoto K, Tokunaga K, Ma RC, So WY, Chan JC, Kamatani N, Makino H, Nanjo K, Kadowaki T, Kasuga M
Journal of human genetics   54(4) 236-241   Apr 2009   [Refereed]
A pilot study suggests that the G/G genotype of resistin single nucleotide polymorphism at -420 may be an independent predictor of a reduction in fasting plasma glucose and insulin resistance by pioglitazone in type 2 diabetes.
Makino H, Shimizu I, Murao S, Kondo S, Tabara Y, Fujiyama M, Fujii Y, Takada Y, Nakai K, Izumi K, Ohashi J, Kawamura R, Yamauchi J, Takata Y, Nishida W, Hashiramoto M, Onuma H, Osawa H
Endocrine journal   56(9) 1049-1058   2009   [Refereed]
Murao S, Imagawa A, Kawasaki E, Yokota K, Yamashita T, Sekikawa T, Osawa H, Hanafusa T, Makino H
Diabetes care   31(10) e69   Oct 2008   [Refereed]
Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, Hirota Y, Mori H, Jonsson A, Sato Y, Yamagata K, Hinokio Y, Wang HY, Tanahashi T, Nakamura N, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Takeda J, Maeda E, Shin HD, Cho YM, Park KS, Lee HK, Ng MC, Ma RC, So WY, Chan JC, Lyssenko V, Tuomi T, Nilsson P, Groop L, Kamatani N, Sekine A, Nakamura Y, Yamamoto K, Yoshida T, Tokunaga K, Itakura M, Makino H, Nanjo K, Kadowaki T, Kasuga M
Nature genetics   40(9) 1092-1097   Sep 2008   [Refereed]
Osawa H, Ochi M, Tabara Y, Kato K, Yamauchi J, Takata Y, Nishida W, Onuma H, Shimizu I, Fujii Y, Miki T, Ohashi J, Makino H
Clinical endocrinology   69(1) 74-80   Jul 2008   [Refereed]
Osawa H, Yamada K, Tabara Y, Ochi M, Onuma H, Nishida W, Shimizu I, Kawamoto R, Fujii Y, Miki T, Ohashi J, Makino H
Clinical endocrinology   69(1) 36-44   Jul 2008   [Refereed]
Murao S, Kondo S, Ohashi J, Fujii Y, Shimizu I, Fujiyama M, Ohno K, Takada Y, Nakai K, Yamane Y, Osawa H, Makino H
Diabetes research and clinical practice   80(1) 114-121   Apr 2008   [Refereed]
Kato K, Osawa H, Ochi M, Kusunoki Y, Ebisui O, Ohno K, Ohashi J, Shimizu I, Fujii Y, Tanimoto M, Makino H
Clinical endocrinology   68(3) 442-449   Mar 2008   [Refereed]
Tabara Y, Osawa H, Kawamoto R, Tachibana-Iimori R, Yamamoto M, Nakura J, Miki T, Makino H, Kohara K
The Journal of clinical endocrinology and metabolism   93(3) 715-722   Mar 2008   [Refereed]
Nakamura M, Nishida W, Yamada Y, Chujo D, Watanabe Y, Imagawa A, Hanafusa T, Kawasaki E, Onuma H, Osawa H, Makino H
Diabetes research and clinical practice   79(2) 220-229   Feb 2008   [Refereed]
Tabara Y, Igase M, Osawa H, Makino H, Miki T, Kohara K
Hypertension (Dallas, Tex. : 1979)   51(2) e11; author reply e12   Feb 2008   [Refereed]
Takata Y, Osawa H, Kurata M, Kurokawa M, Yamauchi J, Ochi M, Nishida W, Okura T, Higaki J, Makino H
Hypertension (Dallas, Tex. : 1979)   51(2) 534-539   Feb 2008   [Refereed]
Yamauchi J, Osawa H, Takasuka T, Ochi M, Murakami A, Nishida W, Onuma H, Takata Y, Tabara Y, Miki T, Ohashi J, Makino H
Metabolism: clinical and experimental   57(2) 149-156   Feb 2008   [Refereed]
Tabara Y, Kawamoto R, Osawa H, Nakura J, Makino H, Miki T, Kohara K
Obesity (Silver Spring, Md.)   16(1) 211-215   Jan 2008   [Refereed]
Miyake K, Horikawa Y, Hara K, Yasuda K, Osawa H, Furuta H, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Makino H, Nanjo K, Kadowaki T, Kasuga M
Journal of human genetics   53(2) 174-180   2008   [Refereed]
Ochi M, Osawa H, Hirota Y, Hara K, Tabara Y, Tokuyama Y, Shimizu I, Kanatsuka A, Fujii Y, Ohashi J, Miki T, Nakamura N, Kadowaki T, Itakura M, Kasuga M, Makino H
Diabetes   56(11) 2834-2838   Nov 2007   [Refereed]
Osawa H, Tabara Y, Kawamoto R, Ohashi J, Ochi M, Onuma H, Nishida W, Yamada K, Nakura J, Kohara K, Miki T, Makino H
Diabetes care   30(6) 1501-1506   Jun 2007   [Refereed]
A case of insulin-induced localized lobular panniculitis with evidence for the phagocytosis of insulin by histiocytes.
Shimizu I, Furuya K, Osawa H, Fujii Y, Makino H
Endocrine journal   54(3) 477-480   Jun 2007   [Refereed]
Tokuyama Y, Osawa H, Ishizuka T, Onuma H, Matsui K, Egashira T, Makino H, Kanatsuka A
Metabolism: clinical and experimental   56(5) 693-698   May 2007   [Refereed]
Osawa H, Ochi M, Kato K, Yamauchi J, Nishida W, Takata Y, Kawamura R, Onuma H, Takasuka T, Shimizu I, Fujii Y, Ohashi J, Makino H
Biochemical and biophysical research communications   355(2) 342-346   Apr 2007   [Refereed]
Onuma H, Osawa H, Ogura T, Tanabe F, Nishida W, Makino H
Biochemical and biophysical research communications   337(3) 976-982   Nov 2005   [Refereed]
A nonsense mutation in the Arg345 of the insulin receptor gene in a Japanese type A insulin-resistant patient.
Hashiramoto M, Osawa H, Ando M, Murakami A, Nishimiya T, Nakano M, Nishida W, Onuma H, Makino H
Endocrine journal   52(4) 499-504   Aug 2005   [Refereed]
Shishino K, Yoshioka Y, Hashimoto K, Ochi M, Aono K, Murase M, Osawa H, Makino H, Saheki S
Annals of clinical biochemistry   42(Pt 4) 298-300   Jul 2005   [Refereed]
Osawa H, Yamada K, Onuma H, Murakami A, Ochi M, Kawata H, Nishimiya T, Niiya T, Shimizu I, Nishida W, Hashiramoto M, Kanatsuka A, Fujii Y, Ohashi J, Makino H
American journal of human genetics   75(4) 678-686   Oct 2004   [Refereed]
The absence of evidence for major effects of the frequent SNP +299G>A in the resistin gene on susceptibility to insulin resistance syndrome associated with Japanese type 2 diabetes.
Ochi M, Osawa H, Onuma H, Murakami A, Nishimiya T, Shimada F, Kato K, Shimizu I, Shishino K, Murase M, Fujii Y, Ohashi J, Makino H
Diabetes research and clinical practice   61(3) 191-198   Sep 2003   [Refereed]
Differences in the contribution of HLA-DR and -DQ haplotypes to susceptibility to adult- and childhood-onset type 1 diabetes in Japanese patients.
Murao S, Makino H, Kaino Y, Konoue E, Ohashi J, Kida K, Fujii Y, Shimizu I, Kawasaki E, Fujiyama M, Kondo S, Tanaka K, Tarumi Y, Seto I, Kato K, Ohno K, Kusunoki Y, Ebisui O, Takada Y, Tanabe K, Takemoto K, Onuma H, Nishimiya T, Osawa H
Diabetes   53(10) 2684-2690   Oct 2004   [Refereed]
Association of fulminant type 1 diabetes with pregnancy.
Shimizu I, Makino H, Osawa H, Kounoue E, Imagawa A, Hanafusa T, Kawasaki E, Fujii Y
Diabetes research and clinical practice   62(1) 33-38   Oct 2003   [Refereed]
Reduction of phosphodiesterase 3B gene expression in peroxisome proliferator-activated receptor gamma (+/-) mice independent of adipocyte size.
Ogura T, Osawa H, Tang Y, Onuma H, Ochi M, Nishimiya T, Kubota N, Terauchi Y, Kadowaki T, Makino H
FEBS letters   542(1-3) 65-68   May 2003   [Refereed]
Systematic search for single nucleotide polymorphisms in the 5' flanking region of the human phosphodiesterase 3B gene: absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes.
Osawa H, Niiya T, Onuma H, Murakami A, Ochi M, Nishimiya T, Ogura T, Kato K, Shimizu I, Fujii Y, Ohashi J, Yamada K, Liang SJ, Manganiello VC, Fujita-Yamaguchi Y, Makino H
Molecular genetics and metabolism   79(1) 43-51   May 2003   [Refereed]
Systematic search for single nucleotide polymorphisms in the FOXC2 gene: the absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes.
Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H
Diabetes   52(2) 562-567   Feb 2003   [Refereed]
Identification of the insulin-regulated interaction of phosphodiesterase 3B with 14-3-3 beta protein.
Onuma H, Osawa H, Yamada K, Ogura T, Tanabe F, Granner DK, Makino H
Diabetes   51(12) 3362-3367   Dec 2002   [Refereed]
Differential regulation of gene expression and insulin-induced activation of phosphodiesterase 3B in adipocytes of lean insulin-resistant IRS-1 (-/-) mice.
Hasegawa M, Tang Y, Osawa H, Onuma H, Nishimiya T, Ochi M, Terauchi Y, Kadowaki T, Makino H
Diabetes research and clinical practice   58(2) 79-85   Nov 2002   [Refereed]
Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study).
Takeda H, Kawasaki E, Shimizu I, Konoue E, Fujiyama M, Murao S, Tanaka K, Mori K, Tarumi Y, Seto I, Fujii Y, Kato K, Kondo S, Takada Y, Kitsuki N, Kaino Y, Kida K, Hashimoto N, Yamane Y, Yamawaki T, Onuma H, Nishimiya T, Osawa H, Saito Y, Makino H, Ehime Study.
Diabetes care   25(6) 995-1001   Jun 2002   [Refereed]
Systematic search for single nucleotide polymorphisms in the resistin gene: the absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes.
Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H
Diabetes   51(3) 863-866   Mar 2002   [Refereed]
Phosphodiesterase 3B gene expression is enhanced in the liver but reduced in the adipose tissue of obese insulin resistant db/db mouse.
Tang Y, Osawa H, Onuma H, Nishimiya T, Ochi M, Sugita A, Makino H
Diabetes research and clinical practice   54(3) 145-155   Dec 2001   [Refereed]
A systematic search for single nucleotide polymorphisms (SNPs) in the insulin receptor gene: association of an SNP with hyperlipidemia in Japanese type 2 diabetic subjects.
Osawa H, Ochi M, Nishimiya T, Onuma H, Nakamaru K, Murakami A, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H
Clinical genetics   60(6) 479-481   Dec 2001   [Refereed]
Activation of mouse phosphodiesterase 3B gene promoter by adipocyte differentiation in 3T3-L1 cells.
Niiya T, Osawa H, Onuma H, Suzuki Y, Taira M, Yamada K, Makino H
FEBS letters   505(1) 136-140   Sep 2001   [Refereed]
Adipocyte-specific reduction of phosphodiesterase 3B gene expression and its restoration by JTT-501 in the obese, diabetic KKAy mouse.
Tang Y, Osawa H, Onuma H, Hasegawa M, Nishimiya T, Ochi M, Makino H
European journal of endocrinology   145(1) 93-99   Jul 2001   [Refereed]
Identification of novel C253Y missense and Y864X nonsense mutations in the insulin receptor gene in type A insulin-resistant patients.
Osawa H, Nishimiya T, Ochi M, Niiya T, Onuma H, Kitamuro F, Kaino Y, Kida K, Makino H
Clinical genetics   59(3) 194-197   Mar 2001   [Refereed]
A complete deficiency of coagulation factor XIII A-subunit due to a novel compound heterozygote of Ser 413 Leu missense and an nt 389 (ins G) frameshift mutation.
Niiya T, Osawa H, Bando S, Oto Y, Tokuda K, Takeda N, Sumioka M, Murase M, Kida K, Makino H
British journal of haematology   107(4) 772-775   Dec 1999   [Refereed]
Improvement in insulin resistance and the restoration of reduced phosphodiesterase 3B gene expression by pioglitazone in adipose tissue of obese diabetic KKAy mice.
Tang Y, Osawa H, Onuma H, Nishimiya T, Ochi M, Makino H
Diabetes   48(9) 1830-1835   Sep 1999   [Refereed]
Yamada K, Wang JC, Osawa H, Scott DK, Granner DK
BioTechniques   24(4) 596-8, 600   Apr 1998   [Refereed]
Mitogen-activated protein kinase and p70 ribosomal protein S6 kinase are not involved in the insulin-dependent stimulation of cAMP phosphodiesterase kinase in rat adipocytes.
Onuma H, Makino H, Osawa H, Suzuki Y, Taira M, Kanatsuka A, Saito Y
Biochimica et biophysica acta   1402(2) 197-208   Mar 1998   [Refereed]
Robey RB, Osawa H, Printz RL, Granner DK
BioTechniques   20(1) 40-42   Jan 1996   [Refereed]
Regulation of hexokinase II gene transcription and glucose phosphorylation by catecholamines, cyclic AMP, and insulin.
Osawa H, Printz RL, Whitesell RR, Granner DK
Diabetes   44(12) 1426-1432   Dec 1995   [Refereed]
Mandarino LJ, Printz RL, Cusi KA, Kinchington P, O'Doherty RM, Osawa H, Sewell C, Consoli A, Granner DK, DeFronzo RA
The American journal of physiology   269(4 Pt 1) E701-8   Oct 1995   [Refereed]
O'Doherty RM, Bracy DP, Osawa H, Wasserman DH, Granner DK
The American journal of physiology   266(2 Pt 1) E171-8   Feb 1994   [Refereed]
Islet amyloid polypeptide/amylin in pancreatic beta-cell line derived from transgenic mouse insulinoma.
Kanatsuka A, Makino H, Yamaguchi T, Ohsawa H, Tokuyama Y, Saitoh T, Yamamura K, Miyazaki J, Yoshida S
Diabetes   41(11) 1409-1414   Nov 1992   [Refereed]
Islet amyloid polypeptide-derived amyloid deposition increases along with the duration of type 2 diabetes mellitus.
Ohsawa H, Kanatsuka A, Mizuno Y, Tokuyama Y, Takada K, Mikata A, Makino H, Yoshida S
Diabetes research and clinical practice   15(1) 17-21   Jan 1992   [Refereed]
Hypersecretion of IAPP from the islets of VMH-lesioned rats and obese Zucker rats.
Tokuyama Y, Kanatsuka A, Ohsawa H, Yamaguchi T, Makino H, Yoshida S, Nagase H, Inoue S
Diabetes research and clinical practice   15(1) 23-29   Jan 1992   [Refereed]
Tokuyama Y, Kanatsuka A, Ohsawa H, Yamaguchi T, Makino H, Yoshida S, Nagase H, Inoue S
Endocrinology   128(6) 2739-2744   Jun 1991   [Refereed]

Misc

 
羽立登志美, 大澤春彦
Monthly Book OCULISTA   (68) 10‐18   Nov 2018
浅田知世, 新家敏之, 玉置南, 川野広大, 宮本仁志, 大澤春彦, 山之内純
愛媛県臨床検査技師会誌   37 57‐60   Mar 2018
大澤春彦, 川村良一, 高田康徳
日本体質医学会雑誌   80(1) 28‐32   Feb 2018
菅野和久, 小泉光仁, 金並真吾, 片山英司, 宮本仁志, 日浅陽一, 大澤春彦, 大澤春彦
臨床化学   47(1) 41‐46   Jan 2018
川村良一, 高田康徳, 大澤春彦
愛媛医学   36(3) 128‐131   Sep 2017

Books etc

 
Peptide Hormones in Pancreas
Biomedical Research Foundation   1990   
Peptide Hormones in Pancreas
Biomedical Research Foundation   1991   

Research Grants & Projects

 
Identification of diabetes susceptibility genes
Project Year: 2000   
Molecular mechanism of insulin resistance
Project Year: 2000   
Analysis of hormonal regulation of gene expression
Project Year: 1991