2012年2月
Abnormal and Direct para-Trifluoroacetylation of Branched Alkyl Phenyl Ketones by Magnesium-Promoted Reductive Aromatic Substitution
SYNLETT
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- 巻
- 23
- 号
- 3
- 開始ページ
- 401
- 終了ページ
- 404
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1055/s-0031-1290325
- 出版者・発行元
- GEORG THIEME VERLAG KG
Magnesium-promoted reduction of branched alkyl phenyl ketones in the presence of ethyl trifluoroacetate and chlorotrimethylsilane in N,N-dimethylformamide (DMF), followed by air oxidation, and the subsequent treatment of tetrabutylammonium fluoride brought about selective and efficient formation of the corresponding aromatic para-substituted diketones possessing a trifluoroacetyl group in good yields through abnormal addition toward the para positions of the aromatic ketones in good yields.
- リンク情報
- ID情報
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- DOI : 10.1055/s-0031-1290325
- ISSN : 0936-5214
- eISSN : 1437-2096
- Web of Science ID : WOS:000300711400015