秋本和憲 (Kazunori Akimoto) - マイポータル

基本情報

所属: 東京理科大学薬学部　生命創薬科学科教授

学位: 博士（薬学）(東京理科大学)

連絡先: akimotors.tus.ac.jp
J-GLOBAL ID: 200901022494423628
researchmap会員ID: 1000225426

外部リンク: https://www.rs.tus.ac.jp/akimotolab/

研究キーワード

研究分野

経歴

学歴

- 1996年

東京理科大学, 薬学部薬学研究科, 薬学
- 1991年

東京理科大学, 薬学部, 薬学科

委員歴

2023年2月 - 2025年1月

日本薬学会関東支部, 幹事

論文

High SLC20A1 Expression Indicates Poor Prognosis in Prostate Cancer

OKAMOTO TAIKI, ONAGA CHOTARO, MATSUOKA IZUMI, OZAKI AYAKA, MATSUDA CHIKA, KASAI TAKAHIRO, XIONG YUYUN, HARADA YOHSUKE, SATO TSUGUMICHI, NAKANO YOSHIO,MANO YASUNARI, MIYAZAKI SATORU, ISHIGURO HITOSHI, SATO KEIKO, TAMORI SHOMA, SASAKI KAZUNORI, OHNO SHIGEO, and AKIMOTO KAZUNORI

Cancer Diagnosis & Prognosis 3-4(4) 439-448 2023年7月査読有り
Foxp3 and Bcl6 deficiency synergistically induces spontaneous development of atopic dermatitis-like skin disease

Yuki Tai, Yuki Sakaida, Riyo Kawasaki, Kaori Kanemaru, Kazunori Akimoto, Frank Brombacher, Shuhei Ogawa, Yoshikazu Nakamura, Yohsuke Harada

INTERNATIONAL IMMUNOLOGY 2023年6月査読有り
High expression of PKCλ and ALDH1A3 indicates a poor prognosis, and PKCλ is required for the asymmetric cell division of ALDH1A3-positive cancer stem cells in PDAC

Takahiro Kasai, Shoma Tamori, Yuta Takasaki, Izumi Matsuoka, Ayaka Ozaki, Chika Matsuda, Yohsuke Harada, Kazunori Sasaki, Shigeo Ohno, Kazunori Akimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 669(20) 85-94 2023年5月23日査読有り
High Expression of CD58 and ALDH1A3 Predicts a Poor Prognosis in Basal-like Breast Cancer

YUYUN XIONG, HITOMI MOTOMURA, SHOMA TAMORI, AYAKA OZAKI, CHOTARO ONAGA, YASUSHI HARA, KEIKO SATO, KOUJI TAHATA, YOHSUKE HARADA, KAZUNORI SASAKI, YUN-WEN ZHENG, SHIGEO OHNO and KAZUNORI AKIMOTO

ANTICANCER RESEARCH 42(11) 5223-5232 2022年11月査読有り
High SLC20A1 Expression Is Associated With Poor Prognosis for Radiotherapy of Estrogen Receptor-positive Breast Cancer

CHOTARO ONAGA, SHOMA TAMORI, IZUMI MATSUOKA, AYAKA OZAKI, HITOMI MOTOMURA, YUKA NAGASHIMA, TSUGUMICHI SATO, KEIKO SATO, KOUJI TAHATA, YUYUN XIONG, YOSHIO NAKANO, YASUNARI MANO, SATORU MIYAZAKI, KAZUNORI SASAKI, SHIGEO OHNO, KAZUNORI AKIMOTO

Cancer Diagnosis&Prognosis 2(4) 429-442 2022年7月査読有り
High Expression of p62 and ALDH1A3 Is Associated With Poor Prognosis in Luminal B Breast Cancer

AYAKA OZAKI, HITOMI MOTOMURA, SHOMA TAMORI, CHOTARO ONAGA, YUKA NAGASHIMA, MAHO KOTORI, CHIKA MATSUDA, AKARI MATSUDA, NANAKO MOCHIZUKI, TSUGUMICHI SATO, YASUSHI HARA, KEIKO SATO, YOHEI MIYAGI, YOJI NAGASHIMA, TAKEHISA HANAWA, YOHSUKE HARADA, YUYUN XIONG, KAZUNORI SASAKI, SHIGEO OHNO and KAZUNORI AKIMOTO

ANTICANCER RESEARCH 42(7) 3299-3312 2022年7月査読有り
High expression of SLC20A1 is less effective for endocrine therapy and predicts late recurrence in ER-positive breast cancer

Chotaro Onaga, Shoma Tamori, Izumi Matsuoka, Ayaka Ozaki, Hitomi Motomura, Yuka Nagashima, Tsugumichi Sato, Keiko Sato, Yuyun Xiong, Kazunori Sasaki, Shigeo Ohno, Kazunori Akimoto

PLoS One 17 2022年5月査読有り
Transcriptomic and Functional Evidence Show Similarities between Human Amniotic Epithelial Stem Cells and Keratinocytes

Li-Ping Liu, Dong-Xu Zheng, Zheng-Fang Xu, Hu-Cheng Zhou, Yun-Cong Wang, Hang Zhou, Jian-Yun Ge, Daisuke Sako, Mi Li, Kazunori Akimoto, Yu-Mei Li, and Yun-Wen Zheng

Cells 11(70) 2022年1月査読有り
Short term but highly efficient Cas9 expression mediated by excisional system using adenovirus vector and Cre

Sayaka Nagamoto, Miyuki Agawa, Emi Tsuchitani, Kazunori Akimoto, Saki Kondo Matsushima, and Yumi Kanegae

Scientific Reports 2021年12月査読有り
GLO 1 and PKCλRegulate ALDH1-positive Breast Cancer Stem Cell Survival

HITOMI MOTOMURA, SHOMA TAMORI, MASA-AKI YATANI, AYANO NAMIKI, CHOTARO ONAGA, AYAKA OZAKI, RYOKO TAKASAWA, YASUNARI MANO, TSUGUMICHI SATO, YASUSHI HARA, KEIKO SATO, XIONG YUYUN, YOHSUKE HARADA, TAKEHISA HANAWA, SEI-ICHI TANUMA, KAZUNORI SASAKI, SHIGEO OHNO and KAZUNORI AKIMOTO

ANTICANCER RESEARCH 41(12) 5959-5971 2021年12月査読有り
Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer

HITOMI MOTOMURA, AYAKA OZAKI, SHOMA TAMORI, CHOTARO ONAGA, YUKA NOZAKI, YUKO WAKI, RYOKO TAKASAWA, KAZUMI YOSHIZAWA, YASUNARI MANO, TSUGUMICHI SATO, KAZUNORI SASAKI, HITOSHI ISHIGURO, YOHEI MIYAGI, YOJI NAGASHIMA, KOUJI YAMAMOTO, KEIKO SATO, TAKEHISA HANAWA, SEI-ICHI TANUMA, SHIGEO OHNO and KAZUNORI AKIMOTO

Oncology Letters 22(1) 547-547 2021年7月査読有り
Generation of two human induced pluripotent stem cell lines derived from two X-linked adrenoleukodystrophy patients with ABCD1 mutations

Yuji Kuramochi, Tomonari Awaya, Mami Matsuo-Takasaki, Miho Takami, Yuri An, Jingyue Li, Yasuko Hemmi, Tamami Wakabayashi, Yutaka Arai, Jun Inoue, Michiya Noguchi, Yukio Nakamura, Isao Asaka, Kazunori Akimoto, Megumu K. Saito, Yohei Hayashi

Stem Cell Research 53 2021年4月査読有り
High SLC20A1 Expression Is Associated With Poor Prognoses in Claudin-low and Basal-like Breast Cancers

CHOTARO ONAGA, SHOMA TAMORI, HITOMI MOTOMURA, AYAKA OZAKI, CHIKA MATSUDA, IZUMI MATSUOKA, TAKUMA FUJITA, YUKA NOZAKI, YASUSHI HARA, YOHEI KAWANO, YOHSUKE HARADA, TSUGUMICHI SATO, YASUNARI MANO, KEIKO SATO, and KAZUNORI AKIMOTO

ANTICANCER RESEARCH 41(1) 43-54 2021年1月査読有り
Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line.

Kobayashi M, Ishizaki Y, Owaki M, Matsumoto Y, Kakiyama Y, Hoshino S, Tagawa R, Sudo Y, Okita N, Akimoto K, Higami Y.

Oncotarget 11(18) 1653-1665 2020年5月査読有り
Five Genes Associated With Survival in Patients With Lower-grade Gliomas Were Identified by Information-theoretical Analysis

KEIKO SATO, KOUJI TAHATA and KAZUNORI AKIMOTO

ANTICANCER RESEARCH 40(5) 2777-2875 2020年5月査読有り
High Expression of c-Met , PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer

HITOMI MOTOMURA, YUKA NOZAKI, CHOTARO ONAGA, AYAKA OZAKI, SHOMA TAMORI, TAKA-AKI SHIINA, SHOTARO KANAI, CHIHIRO OHIRA, YASUSHI HARA, YOHSUKE HARADA, RYOKO TAKASAWA, TAKEHISA HANAWA, SEI-ICHI TANUMA, YASUNARI MANO, TSUGUMICHI SATO, KEIKO SATO and KAZUNORI AKIMOTO

ANTICANCER RESEARCH 40(1) 35-52 2020年1月査読有り
Enhanced hepatic differentiation in the subpopulation of human amniotic stem cells under 3D multicellular microenvironment

Kinji Furuya, Yun-Wen Zheng, Daisuke Sako, Kenichi Iwasaki, Dong-Xu Zheng, Jian-Yun Ge, Li-Ping Liu, Tomoaki Furuta, Kazunori Akimoto, Hiroya Yagi …

World Journal of Stem Cells 11(9) 705-721 2019年9月査読有り
Aberrant nuclear localization of aPKCλ/ι is associated with poorer prognosis in uterine cervical cancer

Aya Tokinaga-Uchiyama, Taichi Mizushima, Kazunori Akimoto, Yoji Nagashima, Kazunori Sasaki, Masa-aki Nakaya, Kenichi Ohashi, Kazumi Kubota, Yasuyo Maruyama, Hisamori Kato …

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY 38(4) 301-309 2019年7月査読有り
Development of Glass-Beads Filters for the Isolation, Culture, and Recollection of Cancer Cells from Blood

Shin Aoki, Babita Shashni, Shinya Ariyasu, Hiroshi Takemura, Kazunori Akimoto, Naoyuki Aiawa, Ken-ichiro Iwasaki, Takayuki Nakanishi, Atsuo Yasumori, Tomohiro Osaki …

International Conference on Cancer Research 2019 (ICCR 2019), London, UK 9-13 2019年6月査読有り
Simple and Convenient Method for the Isolation, Culture, and Re-collection of Cancer Cells from Blood by Using Glass-Bead Filters

Babita Shashni, Hidehiko Matsuura, Riku Saito, Takuma Hirata, Shinya Ariyasu, Kenta Nomura, Hiroshi Takemura, Kazunori Akimoto, Naoyuki Aikawa, Atsuo Yasumori …

ACS Biomaterials Science & Engineering 5(2) 438-452 2019年2月査読有り