Kazunori Akimoto

Profile Information

Affiliation: Professor, Faculty of Pharmaceutical Sciences, Department of Medicinal and Life Sciences, Tokyo University of Science

Degree: Ph.D.(Tokyo University of Science)

Contact information: akimotors.tus.ac.jp
J-GLOBAL ID: 200901022494423628
researchmap Member ID: 1000225426

External link: https://www.rs.tus.ac.jp/akimotolab/

Research Interests

Research Areas

Research History

Apr, 2012 - Present

Associate Professor, Department of Molecular Medical Science, Faculty of Farmaceutical Sciences
Yokohama City University School of Medicine, Department of Molecular Biology

Education

Committee Memberships

Feb, 2023 - Jan, 2025

幹事, 日本薬学会関東支部

Papers

High SLC20A1 Expression Indicates Poor Prognosis in Prostate Cancer

OKAMOTO TAIKI, ONAGA CHOTARO, MATSUOKA IZUMI, OZAKI AYAKA, MATSUDA CHIKA, KASAI TAKAHIRO, XIONG YUYUN, HARADA YOHSUKE, SATO TSUGUMICHI, NAKANO YOSHIO,MANO YASUNARI, MIYAZAKI SATORU, ISHIGURO HITOSHI, SATO KEIKO, TAMORI SHOMA, SASAKI KAZUNORI, OHNO SHIGEO, and AKIMOTO KAZUNORI

Cancer Diagnosis & Prognosis, 3-4(4) 439-448, Jul, 2023 Peer-reviewed
Foxp3 and Bcl6 deficiency synergistically induces spontaneous development of atopic dermatitis-like skin disease

Yuki Tai, Yuki Sakaida, Riyo Kawasaki, Kaori Kanemaru, Kazunori Akimoto, Frank Brombacher, Shuhei Ogawa, Yoshikazu Nakamura, Yohsuke Harada

INTERNATIONAL IMMUNOLOGY, Jun, 2023 Peer-reviewed
High expression of PKCλ and ALDH1A3 indicates a poor prognosis, and PKCλ is required for the asymmetric cell division of ALDH1A3-positive cancer stem cells in PDAC.

Takahiro Kasai, Shoma Tamori, Yuta Takasaki, Izumi Matsuoka, Ayaka Ozaki, Chika Matsuda, Yohsuke Harada, Kazunori Sasaki, Shigeo Ohno, Kazunori Akimoto

Biochemical and biophysical research communications, 669(20) 85-94, May 23, 2023 Peer-reviewed
High Expression ofCD58andALDH1A3Predicts a Poor Prognosis in Basal-like Breast Cancer

YUYUN XIONG, HITOMI MOTOMURA, SHOMA TAMORI, AYAKA OZAKI, CHOTARO ONAGA, YASUSHI HARA, KEIKO SATO, KOUJI TAHATA, YOHSUKE HARADA, KAZUNORI SASAKI …

Anticancer Research, 42(11) 5223-5232, Nov, 2022 Peer-reviewed
High SLC20A1 Expression Is Associated With Poor Prognosis for Radiotherapy of Estrogen Receptor-positive Breast Cancer

CHOTARO ONAGA, SHOMA TAMORI, IZUMI MATSUOKA, AYAKA OZAKI, HITOMI MOTOMURA, YUKA NAGASHIMA, TSUGUMICHI SATO, KEIKO SATO, KOUJI TAHATA, YUYUN XIONG, YOSHIO NAKANO, YASUNARI MANO, SATORU MIYAZAKI, KAZUNORI SASAKI, SHIGEO OHNO, KAZUNORI AKIMOTO

Cancer Diagnosis&Prognosis, 2(4) 429-442, Jul, 2022 Peer-reviewed
High Expression of p62 and ALDH1A3 Is Associated With Poor Prognosis in Luminal B Breast Cancer

AYAKA OZAKI, HITOMI MOTOMURA, SHOMA TAMORI, CHOTARO ONAGA, YUKA NAGASHIMA, MAHO KOTORI, CHIKA MATSUDA, AKARI MATSUDA, NANAKO MOCHIZUKI, TSUGUMICHI SATO …

Anticancer Research, 42(7) 3299-3312, Jul, 2022 Peer-reviewed
High expression of SLC20A1 is less effective for endocrine therapy and predicts late recurrence in ER-positive breast cancer

Chotaro Onaga, Shoma Tamori, Izumi Matsuoka, Ayaka Ozaki, Hitomi Motomura, Yuka Nagashima, Tsugumichi Sato, Keiko Sato, Yuyun Xiong, Kazunori Sasaki, Shigeo Ohno, Kazunori Akimoto

PLoS One, 17, May, 2022 Peer-reviewed
Transcriptomic and Functional Evidence Show Similarities between Human Amniotic Epithelial Stem Cells and Keratinocytes

Li-Ping Liu, Dong-Xu Zheng, Zheng-Fang Xu, Hu-Cheng Zhou, Yun-Cong Wang, Hang Zhou, Jian-Yun Ge, Daisuke Sako, Mi Li, Kazunori Akimoto, Yu-Mei Li, and Yun-Wen Zheng

Cells, 11(70), Jan, 2022 Peer-reviewed
Short term but highly efficient Cas9 expression mediated by excisional system using adenovirus vector and Cre

Sayaka Nagamoto, Miyuki Agawa, Emi Tsuchitani, Kazunori Akimoto, Saki Kondo Matsushima, and Yumi Kanegae

Scientific Reports, Dec, 2021 Peer-reviewed
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival

HITOMI MOTOMURA, SHOMA TAMORI, MASA-AKI YATANI, AYANO NAMIKI, CHOTARO ONAGA, AYAKA OZAKI, RYOKO TAKASAWA, YASUNARI MANO, TSUGUMICHI SATO, YASUSHI HARA …

Anticancer Research, 41(12) 5959-5971, Dec, 2021 Peer-reviewed
Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer.

Hitomi Motomura, Ayaka Ozaki, Shoma Tamori, Chotaro Onaga, Yuka Nozaki, Yuko Waki, Ryoko Takasawa, Kazumi Yoshizawa, Yasunari Mano, Tsugumichi Sato …

Oncology letters, 22(1) 547-547, Jul, 2021 Peer-reviewed
Generation of two human induced pluripotent stem cell lines derived from two X-linked adrenoleukodystrophy patients with ABCD1 mutations

Yuji Kuramochi, Tomonari Awaya, Mami Matsuo-Takasaki, Miho Takami, Yuri An, Jingyue Li, Yasuko Hemmi, Tamami Wakabayashi, Yutaka Arai, Jun Inoue, Michiya Noguchi, Yukio Nakamura, Isao Asaka, Kazunori Akimoto, Megumu K. Saito, Yohei Hayashi

Stem Cell Research, 53, Apr, 2021 Peer-reviewed
High SLC20A1 Expression Is Associated With Poor Prognoses in Claudin-low and Basal-like Breast Cancers.

Chotaro Onaga, Shoma Tamori, Hitomi Motomura, Ayaka Ozaki, Chika Matsuda, Izumi Matsuoka, Takuma Fujita, Yuka Nozaki, Yasushi Hara, Yohei Kawano …

Anticancer research, 41(1) 43-54, Jan, 2021 Peer-reviewed
Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line.

Kobayashi M, Ishizaki Y, Owaki M, Matsumoto Y, Kakiyama Y, Hoshino S, Tagawa R, Sudo Y, Okita N, Akimoto K, Higami Y.

Oncotarget, 11(18) 1653-1665, May, 2020 Peer-reviewed
Five Genes Associated With Survival in Patients With Lower-grade Gliomas Were Identified by Information-theoretical Analysis

KEIKO SATO, KOUJI TAHATA and KAZUNORI AKIMOTO

ANTICANCER RESEARCH, 40(5) 2777-2875, May, 2020 Peer-reviewed
High Expression of c-Met, PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer

HITOMI MOTOMURA, YUKA NOZAKI, CHOTARO ONAGA, AYAKA OZAKI, SHOMA TAMORI, TAKA-AKI SHIINA, SHOTARO KANAI, CHIHIRO OHIRA, YASUSHI HARA, YOHSUKE HARADA …

Anticancer Research, 40(1) 35-52, Jan, 2020 Peer-reviewed
Enhanced hepatic differentiation in the subpopulation of human amniotic stem cells under 3D multicellular microenvironment

Kinji Furuya, Yun-Wen Zheng, Daisuke Sako, Kenichi Iwasaki, Dong-Xu Zheng, Jian-Yun Ge, Li-Ping Liu, Tomoaki Furuta, Kazunori Akimoto, Hiroya Yagi …

World Journal of Stem Cells, 11(9) 705-721, Sep, 2019 Peer-reviewed
Aberrant Nuclear Localization of aPKCλ/ι is Associated With Poorer Prognosis in Uterine Cervical Cancer.

Aya Tokinaga-Uchiyama, Taichi Mizushima, Kazunori Akimoto, Yoji Nagashima, Kazunori Sasaki, Masa-Aki Nakaya, Kenichi Ohashi, Kazumi Kubota, Yasuyo Maruyama, Hisamori Kato …

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 38(4) 301-309, Jul, 2019 Peer-reviewed
Development of Glass-Beads Filters for the Isolation, Culture, and Recollection of Cancer Cells from Blood

Shin Aoki, Babita Shashni, Shinya Ariyasu, Hiroshi Takemura, Kazunori Akimoto, Naoyuki Aiawa, Ken-ichiro Iwasaki, Takayuki Nakanishi, Atsuo Yasumori, Tomohiro Osaki …

International Conference on Cancer Research 2019 (ICCR 2019), London, UK, 9-13, Jun, 2019 Peer-reviewed
Simple and Convenient Method for the Isolation, Culture, and Re-collection of Cancer Cells from Blood by Using Glass-Bead Filters

Babita Shashni, Hidehiko Matsuura, Riku Saito, Takuma Hirata, Shinya Ariyasu, Kenta Nomura, Hiroshi Takemura, Kazunori Akimoto, Naoyuki Aikawa, Atsuo Yasumori …

ACS Biomaterials Science & Engineering, 5(2) 438-452, Feb, 2019 Peer-reviewed

Misc.

PKC lambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

M Matsumoto, W Ogawa, K Akimoto, H Inoue, K Miyake, K Furukawa, Y Hayashi, H Iguchi, Y Matsuki, R Hiramatsu …

JOURNAL OF CLINICAL INVESTIGATION, 112(6) 935-944, Sep, 2003
Protein kinase C lambda/iota (PKC lambda/iota): A PKC isotype essential for the development of multicellular organisms

A Suzuki, K Akimoto, S Ohno

JOURNAL OF BIOCHEMISTRY, 133(1) 9-16, Jan, 2003
Dynamic changes in protein components of the tight junction during liver regeneration

Y Takaki, S Hirai, N Manabe, Y Izumi, T Hirose, M Nakaya, A Suzuki, K Mizuno, K Akimoto, S Tsukita …

CELL AND TISSUE RESEARCH, 305(3) 399-409, Sep, 2001
Atypical protein kinase C is involved in the evolutionarily conserved PAR protein complex and plays a critical role in establishing epithelia-specific junctional structures

A Suzuki, T Yamanaka, T Hirose, N Manabe, K Mizuno, M Shimizu, K Akimoto, Y Izumi, T Ohnishi, S Ohno

JOURNAL OF CELL BIOLOGY, 152(6) 1183-1196, Mar, 2001
Dymamicchanger in Protein Components of the tight Junction During Ltuer Regeneration

Cell Tissue Res, 305, 399-409, 2001
Meiotic maturation induces animal-vegetal asymmetric distribution of aPKC and ASIP/PAR-3 in Xenopus oocytes

M Nakaya, A Fukui, Y Izumi, K Akimoto, M Asashima, S Ohno

DEVELOPMENT, 127(23) 5021-5031, Dec, 2000
Requirement of atypical protein kinase C lambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

K Kotani, W Ogawa, M Matsumoto, T Kitamura, H Sakaue, Y Hino, K Miyake, W Sano, K Akimoto, S Ohno …

MOLECULAR AND CELLULAR BIOLOGY, 18(12) 6971-6982, Dec, 1998
Atypical protein kinase C lambda binds and regulates p70 S6 kinase

K Akimoto, M Nakaya, T Yamanaka, J Tanaka, S Matsuda, QP Weng, J Avruch, S Ohno

BIOCHEMICAL JOURNAL, 335 417-424, Oct, 1998
Involvement of protein kinase C in the activation of extracellular signal-regulated kinase 1/2 by UVC irradiation

SG Zhuang, S Hirai, K Mizuno, A Suzuki, K Akimoto, Y Izumi, A Yamashita, S Ohno

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 240(2) 273-278, Nov, 1997
プロテインキナーゼとホスファターゼ

実験医学.別冊:シグナル伝達実験法, 153-161, 1996
Dominant regative effect of the truncated p110 subunit of phosphatioly linositol-3 Kinase

Biochem. Mol. Biol. Int., 39(4) 721-728, 1996
Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase

S Moriya, A Kazlauskas, K Akimoto, S Hirai, K Mizuno, T Takenawa, Y Fukui, Y Watanabe, S Ozaki, S Ohno

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 93(1) 151-155, Jan, 1996
EGF and PDGF receptors activate atypical PKCλ through phosphatiolylinositol 3-Kinase

EMBO JOURNAL, 15(4) 788-798, 1996
PHOSPHATIDYLINOSITOL 3-KINASE IS INVOLVED IN TRE-DEPENDENT GENE-EXPRESSION IN RESPONSE TO ARGININE-VASOPRESSIN

N NISHIOKA, K AKIMOTO, S MORIYA, J TAKAYANAGI, Y FUKUI, SI HIRAI, K MIZUNO, K KOSAKA, S OHNO

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 215(3) 1037-1042, Oct, 1995
PI3キナーゼを介したPKCの活性化

実験医学,羊土社, 13(5月) 50-54, 1995
ACTIVATION OF NOVEL PROTEIN-KINASES C-DELTA AND C-EPSILON UPON MITOGENIC STIMULATION OF QUIESCENT RAT 3Y1 FIBROBLASTS

S OHNO, K MIZUNO, Y ADACHI, A HATA, Y AKITA, K AKIMOTO, S OSADA, S HIRAI, K SUZUKI

JOURNAL OF BIOLOGICAL CHEMISTRY, 269(26) 17495-17501, Jul, 1994
A NEW MEMBER OF THE 3RD CLASS IN THE PROTEIN-KINASE-C FAMILY, PKC-LAMBDA, EXPRESSED DOMINANTLY IN AN UNDIFFERENTIATED MOUSE EMBRYONAL CARCINOMA CELL-LINE AND ALSO IN MANY TISSUES AND CELLS

K AKIMOTO, K MIZUNO, S OSADA, S HIRAI, S TANUMA, K SUZUKI, S OHNO

JOURNAL OF BIOLOGICAL CHEMISTRY, 269(17) 12677-12683, Apr, 1994
プロテインキナーゼC

細胞工学,別冊:アポトーシス実験プロトコール秀潤社, 216-224, 1994
PI3キナーゼとプロテインキナーゼC

組織培養,ニューサイエンス社, 20(3月) 8-12, 1994
PREDOMINANT EXPRESSION OF NPKC-ETA, A CA2+-INDEPENDENT ISOFORM OF PROTEIN-KINASE-C IN EPITHELIAL TISSUES, IN ASSOCIATION WITH EPITHELIAL DIFFERENTIATION

S OSADA, Y HASHIMOTO, S NOMURA, Y KOHNO, K CHIDA, O TAJIMA, K KUBO, K AKIMOTO, H KOIZUMI, Y KITAMURA …

CELL GROWTH & DIFFERENTIATION, 4(3) 167-175, Mar, 1993

Books and Other Publications

Science Forum 科学フォーラム vol. 433 2023年2月号「情報論を切り口とした晩期再発乳がんのバイオマーカーの探索」

多森翔馬、翁長朝太郎、秋本和憲 (Role: Joint author)

東京理科大学, Feb 1, 2023
Science Forum 科学フォーラム vol. 431 こんな先生いるよ「がんの精密医療の道のりはまだ長い」

秋本和憲

東京理科大学, Oct 1, 2022
「Precision Medicine」臨時増刊号ゲノム情報とオミックス情報を活用した「予防医学」情報論・統計解析手法を用いたがんゲノミクスデータ解析による乳がん患者層別化

秋本和憲・多森翔馬・翁長朝太郎・野崎優香・本村瞳・尾崎綾栞・熊御雲・田畑耕治・佐藤圭子 (Role: Joint author)

北隆館, Dec 10, 2021
月刊「Precision Medicine」11月号リキッドバイオプシーによるゲノム医療情報論・統計解析手法を用いたがんゲノミクスデータ解析による乳がん患者層別化

秋本和憲・多森翔馬・翁長朝太郎・野崎優香・本村瞳・尾崎綾栞・熊御雲・田畑耕治・佐藤圭子 (Role: Joint author)

北隆館, Nov 25, 2021
月刊「細胞」１０月臨時増刊号新規細胞死機構が制御する生体応答がんゲノミクスデータ解析を起点としたがん幹細胞の生存機構の解明

多森翔馬、本村瞳、野崎優香、尾崎綾栞、翁長朝太郎、佐藤圭子、秋本和憲 (Role: Joint author)

ニューサイエンス社, Oct 30, 2021
月刊「細胞」特集ゲノムデータを駆使した医学研究がんゲノミクスデータ解析を起点としたがん幹細胞の生存機構の解明

多森翔馬、本村瞳、野崎優香、佐藤圭子、秋本和憲 (Role: Joint author)

ニューサイエンス社, Jul 20, 2021
図解腫瘍薬学

小茂田昌代、秋本和憲、斎藤光江 (Role: Joint author)

南山堂, Aug 1, 2020
図解腫瘍薬学

秋本和憲

南山堂, Aug 1, 2020
理大科学フォーラム「難治性乳癌制圧プロジェクト」

秋本和憲

東京理科大学, Aug 1, 2019
理工系の基礎薬学

鍜冶利幸, 花輪剛久, 嶋田修治, 東達也, 真野泰成, 羽田紀康, 髙澤涼子, 礒濱洋一郎, 根岸健一, 伊集院一成, 後藤了, 横山英志, 西川元也, 月本光俊, 稲見圭子, 秋本和憲, 原田陽介, 早川洋一, 市原学, 吉澤一巳, 佐藤嗣道, 山下親正, 鈴木立紀, 河野弥生, 上村直樹, 鹿村恵明 (Role: Joint author)

丸善出版, Mar 31, 2018 (ISBN: 9784621302835)
ゲノム創薬科学

秋本和憲 (Role: Joint author)

裳華房, Oct 20, 2017
理大科学フォーラム続「大鍋の底抜け」

秋本和憲

東京理科大学, Oct 1, 2017
理大科学フォーラム「がん幹細胞の理解から創薬へ」

秋本和憲

東京理科大学, Jun 1, 2017
理大科学フォーラム「変わりつつある理大生の悪しき伝統」

秋本和憲

東京理科大学, Jun 1, 2016
理工系の基礎生命科学入門

池北雅彦, 武村政春, 鳥越秀峰, 田村浩二, 水田龍信, 橋本茂樹, 太田尚孝, 鞆達也, 和田直之, 松永幸大, 吉澤一巳, 鈴木智順, 秋本和憲 (Role: Joint author)

丸善出版, Apr 25, 2016
理大科学フォーラム「大鍋の底抜け」

秋本和憲

東京理科大学, Sep 1, 2014
東京理科大学坊っちゃん科学シリーズ４『生命科学がひらく未来』第３章細胞の仕組みとその運命

秋本和憲

東京理科大学出版センター編東京書籍, Apr, 2013
理大科学フォーラム「秋本研究室」医学と薬学の橋渡し

秋本和憲

東京理科大学, Jan 1, 2013
１０年後、２０年後を見すえた基礎研究の現場から Whistle plus 進展する医療研究拠点形成プロジェクト

秋本和憲, 佐々木和教 (Role: Editor)

横浜市立大学先端医科学研究課発行, May, 2012
レーザーマイクロダイセクションシステム（微小組織・細胞回収システム）

秋本和憲, 大野茂男 (Role: Joint author)

横浜医学横浜市立大学医学会, Feb, 2012

Presentations

181

がん幹細胞の非対称分裂を起点としたがん組織不均一性獲得機構の解明

葛西隆広、多森翔馬、高崎湧太、佐々木和教、大野茂男、秋本和憲

第67回日本薬学会関東支部大会, Sep 16, 2023
p62の高発現はLuminalB型乳がんALDH1A 3陽性がん幹細胞におけるホルモン療法抵抗性と予後不良に関連する

前村祐希、尾崎綾栞、翁長朝太郎、長島佑夏、多森翔馬、佐々木和教、大野茂男、秋本和憲

第67回日本薬学会関東支部大会, Sep 16, 2023
中枢神経系網膜の細胞極性と細胞運命決定 Cell polarity and fate determination of the mammalian retina

上野明希子、澤田綾、井上祐介、前嶋千瀬都、石橋拓也、秋本和憲、大野茂男、小池千恵子

日本薬学会第１４３回年会一般シンポジウム S55, Mar 25, 2023
がん幹細胞の非対称分裂制御機構の解明 Analysis of novel molecular mechanisms regulating asymmetric division of cancer stem cells

多森翔馬、秋本和憲

日本薬学会第１４３回年会一般シンポジウム S55, Mar 25, 2023
PKCλは膵臓がん幹細胞の非対称分裂制御に関与する

葛西隆広、多森翔馬、髙﨑湧太、佐々木和教、大野茂男、秋本和憲

日本薬学会第143年会, Mar 25, 2023
p62とALDH1A3遺伝子共高発現luminal B型乳癌は予後不良である

尾崎綾栞、本村瞳、多森翔馬、翁長朝太郎、長島佑夏、小鳥真歩、松田千佳、松田あかり、望月菜々子、佐藤嗣道、原泰志、佐藤圭子、宮城洋平、長嶋洋治、花輪剛久、原田陽介、熊御云、佐々木和教、大野茂男、秋本和憲

日本薬学会第143年会, Mar 25, 2023
CD58とALDH1A3の高発現はBasal-like型乳がん患者の予後不良に関与する

熊御云、本村瞳、多森翔馬、尾﨑綾栞、翁長朝太郎、原泰志、佐藤圭子、田畑耕治、原田陽介、佐々木和教、鄭允文、大野茂男、秋本和憲

日本薬学会第143年会, Mar 25, 2023
ヘパラナーゼ遺伝子の発現はaPKC-NF-κBシグナリングによって制御されているHeparanase gene expression is regulated by aPKC-NF-κB signaling

宮下佳那美, 米野雅大, 三尋木結花, 三輪有由奈, 多森翔馬, 秋本和憲, 東伸昭, 須田貴司, 東恭平

第95回（2022年）日本生化学会大会, Nov 9, 2022
SLC20A1高発現はER陽性型乳がんのホルモン療法抵抗性と晩期再発に関わる

翁長朝太郎、多森翔馬、尾崎綾栞、本村瞳、佐々木和教、大野茂男、秋本和憲

第81回日本癌学会学術総会, Oct 1, 2022
p62とALDH1A3遺伝子共高発現Luminal B型乳癌は予後不良である

尾崎綾栞、本村瞳、多森翔馬、翁長朝太郎、佐々木和教、大野茂男、秋本和憲

第81回日本癌学会学術総会, Sep 30, 2022
NEW APPROACH FOR BREAST CANCER STRATIFICATION BASED ON CANCER GENOMICS DB

Kazunori Akimoto

The 9th International Postgraduate Conference on Pharmaceutical Sciences 2022, Jun 21, 2022
High expression of SLC20A1 is less effective for endocrine therapy and predicts late recurrence in ER-positive breast cancer

Chotaro Oaga, Shoma Tamori, Kazunori Akimoto

The 9th International Postgraduate Conference on Pharmaceutical Sciences 2022, Jun 21, 2022
High expression of p62 and ALDH1A3 is associated with poor prognosis in luminal B breast cancer

Ayaka Ozaki, Shoma Tamori, Kazunori Akimoto

The 9th International Postgraduate Conference on Pharmaceutical Sciences 2022, Jun 21, 2022
がんゲノミクスデータベース解析を基盤とした細胞極性因子によるがん幹細胞性維持機構の解明

秋本和憲

微生物化学研究所セミナー, Mar 30, 2022
がんゲノミクスデータ解析を起点とした無機リン酸共輸送体SLC20A1のALDH1陽性膵臓がん幹細胞における役割解析 Analysis of the role of SLC20A1 in ALDH1 positive pancreatic cancer stem cells based on cancer genomics data

松岡泉、翁長朝太郎、多森翔馬、石井雅貴、佐藤圭子、佐々木和教、大野茂男、秋本和憲

日本薬学会第142年会, Mar 26, 2022
がんゲノミクスデータ解析によるProtein Kinase C ζ（PKCζ）の乳がん幹細胞における役割の解析 Analysis of the role of Protein Kinase C ζ(PKCζ) in ALDH1 positivebreast cancer stem cells based on cancer genomics data

長島佑夏、多森翔馬、本村瞳、尾﨑綾栞、翁長朝太郎、佐々木和教、大野茂男、秋本和憲

日本薬学会第142年会, Mar 26, 2022
p62とALDH1A3遺伝子共高発現Luminal B型乳癌は予後不良である High p62 and ALDH1A3 expressions are associated with poorprognosis in Luminal B breast cancer

尾崎綾栞、多森翔馬、本村瞳、翁長朝太郎、長島佑夏、小鳥真歩、松田あかり、望月菜々子、佐々木和教、大野茂男、秋本和憲

日本薬学会第142年会, Mar 26, 2022
Design and Synthesis of Optically Pure Triscyclometalated Iridium(III) Complex-Peptide Hybrids for the Use in Biological and Material Sciences

Azusa Kanbe, Kenta Yokoi Seiya Nakagawa, Tomohiro Tanaka, Hitomi Motomura, Kazunori Akimoto and Shin Aoki

2020/2021 International Chemical Congress of Pacific Basin Societies (PACICHEM2020/2021), Dec 16, 2021
Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer

本村瞳、尾崎綾栞、多森翔馬、野崎優香、高澤涼子、佐々木和教、石黒斉、宮城洋平、長嶋洋治、田沼靖一、大野茂男、秋本和憲

第80回日本癌学会学術総会, Sep 30, 2021
High SLC20A1 expression is associated with poor prognosis in claudin-low and basal-like breast cancers

Onaga C., Tamori S., Motomura H., Ozaki A., Matsuda C., Matsuoka I., Fujita T., Nozaki Y., Hara Y., Kawano Y., Harada Y., Sato T., Mano Y., Sato K., Akimoto K.

International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021, Sep 28, 2021

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