田邉由幸 (Yoshiyuki Tanabe) - マイポータル - researchmap

基本情報

所属: 岩手医科大学薬学部分子細胞薬理学講座准教授

学位: 博士(薬学)(東京大学)
薬学修士(明治薬科大学)

J-GLOBAL ID: 200901032188268053
researchmap会員ID: 1000225481

研究キーワード

2

研究分野

2

論文

23

Role of Secretory Phospholipase A(2) in Rhythmic Contraction of Pulmonary Arteries of Rats With Monocrotaline-Induced Pulmonary Arterial Hypertension

Yoshiyuki Tanabe, Maki Saito-Tanji, Yuki Morikawa, Akihisa Kamataki, Takashi Sawai, Koichi Nakayama

JOURNAL OF PHARMACOLOGICAL SCIENCES 119(3) 271-281 2012年7月査読有り
Inhibition of Untransformed Prostaglandin H-2 Production and Stretch-Induced Contraction of Rabbit Pulmonary Arteries by Indoxam, a Selective Secretory Phospholipase A(2) Inhibitor

Yoshiyuki Tanabe, Maki Saito, Yuki Morikawa, Akihisa Kamataki, Takashi Sawai, Masamichi Hirose, Koichi Nakayama

JOURNAL OF PHARMACOLOGICAL SCIENCES 115(4) 525-531 2011年4月査読有り
Rho and Rho-Kinase Activity in Adipocytes Contributes to a Vicious Cycle in Obesity That May Involve Mechanical Stretch

Yoshikazu Hara, Shu Wakino, Yoshiyuki Tanabe, Maki Saito, Hirobumi Tokuyama, Naoki Washida, Satoru Tatematsu, Kyoko Yoshioka, Koichiro Homma, Kazuhiro Hasegawa …

SCIENCE SIGNALING 4(157) ra3 2011年1月査読有り
Involvement of cyclooxygenase-2 in synergistic effect of cyclic stretching and eicosapentaenoic acid on adipocyte differentiation

Yoshiyuki Tanabe, Yumi Matsunaga, Maki Saito, Koichi Nakayama

JOURNAL OF PHARMACOLOGICAL SCIENCES 106(3) 478-484 2008年3月査読有り
Effects of olmesartan, an AT1 receptor antagonist, on hypoxia-induced activation of ERK1/2 and pro-inflammatory signals in the mouse lung

Yoshiyuki Tanabe, Yuki Morikawa, Takao Kato, Satoshi Kanai, Taichi Watakabe, Ami Nishijima, Hijiri Iwata, Kaori Isobe, Mayumi Ishizaki, Koichi Nakayama

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 374(3) 235-248 2006年12月査読有り
Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice

Y Ito, K Obara, R Ikeda, M Ishii, Y Tanabe, T Ishikawa, K Nakayama

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 451(6) 803-813 2006年3月査読有り
Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice

Y Ito, K Obara, R Ikeda, M Ishii, Y Tanabe, T Ishikawa, K Nakayama

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 451(6) 803-813 2006年3月査読有り
Inhibition of adipocyte differentiation by mechanical stretching through ERK-mediated downregulation of PPAR gamma(2)

Y Tanabe, M Koga, M Saito, Y Matsunaga, K Nakayama

JOURNAL OF CELL SCIENCE 117(16) 3605-3614 2004年7月
Inhibition of adipocyte differentiation by mechanical stretching through ERK-mediated down-regulation of PPARγ2.

Journal of Cell Science 117(16) 3605-3614 2004年7月査読有り
Inhibition of adipocyte differentiation by mechanical stretching through ERK-mediated downregulation of PPAR gamma(2)

Y Tanabe, M Koga, M Saito, Y Matsunaga, K Nakayama

JOURNAL OF CELL SCIENCE 117(16) 3605-3614 2004年7月査読有り
Mechanical stretching inhibits adipocyte differentiation of 3T3-L1 cells: The molecular mechanism and pharmacological regulation

Yoshiyuki Tanabe, Koichi Nakayama

Folia Pharmacologica Japonica 124(5) 337-344 2004年査読有り
Endothelium-derived prostaglandin H-2 evokes the stretch-induced contraction of rabbit pulmonary artery

M Saito, Y Tanabe, Kudo, I, K Nakayama

EUROPEAN JOURNAL OF PHARMACOLOGY 467(1-3) 151-161 2003年4月
Endothelium-derived prostaglandin H-2 evokes the stretch-induced contraction of rabbit pulmonary artery

M Saito, Y Tanabe, Kudo, I, K Nakayama

EUROPEAN JOURNAL OF PHARMACOLOGY 467(1-3) 151-161 2003年4月査読有り
Interactive role fo tyrosine kinase, protein kinase C, and Rho/Rho kinase systems in the mechanotransduction of vascular smooth muscles.

Biorheology 40: 307-314 2003年
Mechanical stress and cerebrovascular response - Resemblance to cerebral vasospasm after subarachnoid hemorrhage

Koichi Nakayama, Kazuo Obara, Yoshiyuki Tanabe, Tomohisa Ishikawa, Shigeru Nishizawa, Masayo Koide

Folia Pharmacologica Japonica 122(1) 33P-36P 2003年査読有り
20-Hydroxyeicosatetraenoic acid potentiates contractile activation of canine basilar artery in response to stretch via protein kinase Calpha-mediated inhibition of calcium-activated potassium channel.

Nakayama K, Obara K, Tanabe Y, Ishikawa T

Advances in experimental medicine and biology 538 411-6; discussion 416 2003年査読有り
Interactive role of tyrosine kinase, protein kinase C, and Rho/Rho kinase systems in the mechanotransduction of vascular smooth muscles

K Nakayama, K Obara, Y Tanabe, M Saito, T Ishikawa, S Nishizawa

BIORHEOLOGY 40(1-3) 307-314 2003年査読有り
Attenuation of pressure-induced myogenic contraction and tyrosine phosphorylation by fasudil, a cerebral vasodilator, in rat cerebral artery.(共著)

Br. J. Pharmacol. 130(2) 219-230 2000年
Mechanical stretch augments PDGF receptor β expression and protein tyrosine phosphorylation in pulmonary artery tissue and smooth muscle cells.(共著)

Mol Cell Biochem 215(1/2) 103-113 2000年
Specific inhibition of stretch-induced increase in L-type calcium channel currents by herbimycin A in canine basilar arterial myocytes.(共著)

Br. J. Pharmacol. 130(4) 923-931 2000年

もっとみる

書籍等出版物

1

20-hydroxyeicosatetraenoic acid potentiates contractile activation of canine basilar artery in response to stretch via protein kinase C alpha-mediated inhibition of calcium-activated potassium channel.

MOLECULAR AND CELLULAR ASPECTS OF MUSCLE CONTRACTION ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 2003年

所属学協会

4

共同研究・競争的資金等の研究課題

7

細胞のメカニカルストレス反応を標的とする代謝症候群および循環系疾患制御の新戦略

科学研究費補助金 2010年 - 2012年
バイオメカニクス刺激による脂肪細胞の機能変化の分子機構

科学研究費補助金
実験的肺高血圧症の誘導期における内因性病因物質の経時的遺伝子発現とその制御

科学研究費補助金
血管平滑筋のバイオメカニクス反応におけるチロシンリン酸化による制御機構に関する研究

科学研究費補助金
Molecular mechanisms of functional differentiation of adipocytes by biomechanical stimulations

Grant-in-Aid for Scientific Research
Gene expression and its regulation of endogenous pathogenic factor during development of experimental pulmonary hypertension.

Grant-in-Aid for Scientific Research
Study on tyrosine phosphorylation in the regulatory mechanisms of biomechanical responses of vascular smooth muscle.

Grant-in-Aid for Scientific Research