TAKEDA Kazuyoshi

J-GLOBAL         Last updated: Oct 10, 2019 at 13:26
 
Avatar
Name
TAKEDA Kazuyoshi

Research Areas

 
 

Education

 
 
 - 
1987
Faculty of Dentistry, Tohoku University
 

Published Papers

 
Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity.
Matsumura, Y., Ito, Y., Mezawa, Y., Sulidan, K., Daigo, Y., Hiraga, T., Mogushi, K., Wali, N., Polanska, U., Suzuki, H., Itoh, T., Miyagi, Y., Yokose, T., Shimizu, S., Takano, A., Terao, Y., Saeki, H., Ozawa, M., Abe, M., Takeda, S., Okumura, K., Habu, S., Hino, O., Takeda, K., Hamada, M., and Orimo, A.
Life Sci. Alliance   2(4) e201900425   Jul 2019   [Refereed]
CD96 is and immune checkpoint that regulated CD8+ T-cell antitumor function.
Mittal, D., Lepletier, A., Madore, J., Aguilera, A. R., Stannard, K., Blake, S. J., Whitehall, V. J. L., Liu, C., Bettington, M. L., Takeda, K, Long, G. V., Scolyer, R. A., Lan, R., Siemers, N., Korman, A., Teng, M. W. L., Johnston, R. J., Dougall, W. C., and Smyth, M. J.
Cancer Immunol Res.   7(4) 559-571   Apr 2019   [Refereed]
The dark side of IFN-γ: Its role in promoting cancer immunoevasion.
Mojic, M., Takeda, K., and Hayakawa, Y.
Int. J. Mol. Sci.   19(1) 89   2018   [Refereed]
ncreased diversity with reduced “ diversity evenness” of tumor infiltrating T-cells for the successful cancer immunotherapy.
Hosoi, A., Takeda, K., Nagaoka, K., Iino, T., Matsushita, H., Ueha, S., Aoki, S., Matsushima, K., Kubo, M., Morikawa, T., Kitaura, K., Suzuki, R., and Kakimi, K.
Scientific Reports   8 1058   2018   [Refereed]
Takeda, K., Nagamatsu, K., and Okumura, K.
J. Ethnopharmacol.   218 51-58   2018   [Refereed]
CD96 targeted antibodies need not block CD96-CD155 interactions to promote NK cell anti-metastatic activity.
Aguilera, A. M., Lutzky, V. P., Mittal, D., Li X.-Y., Stannard, K., Takeda, K., Bernhardt, G., Teng, M. W. L., Dougall, W. C., and Smyth M.J.
OncoImmunology   7(5) e1424677   2018   [Refereed]
Quantitative T cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination.
Takeda, K., Kitaura, K., Suzuki, R., Owada, Y., Muto, S., Okabe, N., Hasegawa, T., Osugi, J., Hoshino, M., Tsunoda, T., Okumura, K., and Suzuki, H.
Cancer Immunol. Immunother.   67(6) 946-964   2018   [Refereed]
CD155 loss enhances tumor suppression via combined host and tumor-intrinsic mechanisms.
Li, X. Y., Das, I., Lepletier, A., Addala, V., Bald, T., Stannard, K., Barkauskas, D, Liu, J., Aguilera A. R., 
Takeda, K., Braun, M., Nakamura, K., Jacquelin, S., Steven W. Lane, S. W., Teng, M. W. L., Dougal, W. C., and Smyth, M. J.
J. CIin. Invest.   128(6) 2613-2625   2018   [Refereed]
Deficiency of host CD96 and PD-1 or TIGIT enhances tumor immunity without significantly compromising immune homeostasis
Harjunpää, H., Blake, S. J., Ahern, E., Allen, S., Liu, J., Yan, J., Lutzky, V., Takeda, K., Aguilera, A. R., Guillerey C., Mittal, D., Li, X. Y., Dougall, W. C., Smyth, M. J., and Teng, M. W. L.
OncoImmunology   26(7) e1445949   2018   [Refereed]
Experimental lung metastases in mice are more effectively inhibited by blockade of IL-23R than IL-23.
Yan, J., Allen, S., Vijayan, D., Li, X. Y., Harjunpää, H., Takeda, K., Liu, J., Cua, D. J., Smyth, M. J., and Teng, M. W. L.
Cancer Immunol. Res.   6(8) 978-987   2018   [Refereed]
Obara, W., Karashima, T., Takeda, K., Kato, R., Kato, Y., Kanehira, M., Takata, R., Inoue, K., Katagiri, T., Shuin, T., Nakamura, Y. and Fujioka, T.
Cancer Immunol. Immunother.   66(1) 17-24   2017   [Refereed]
IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting.
Takeda, K., Nakayama, M., Hayakawa, Y., Kojima, Y., Ikeda, H., Naoko Imai, N., Ogasawara, K., Okumura, K., Thomas, D. M. and Smyth, M. J.
Nature Commun.   8 14607   2017   [Refereed]
Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis.
Putz, E. M., Guillerey, C., Kos, K., Stannard, K., Miles, K., Delconte, R. B., Takeda, K., Nicholson, S. E., Huntington, N. D. and Smyth, M. J.
Oncoimmunology   6(2) e1267892   2017   [Refereed]
Selective activation of anti-CD73 mechanisms in control of primary tumors and metastases.
Vijayan, D., Barkauskas, D., Young, A., Stannard, K., Sult, E., Buonpane, R., Takeda, K., Teng, M. W. L., Sachsenmeier, K. F., Hay, C. and Smyth, M. J.
Oncoimmunology   6(5) e1312044   2017   [Refereed]
Plasminogen activator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice.
Honjo, K., Munakata, S., Tashiro, Y., Salama, Y., Shimazu, H., Eiamboonsert,
 S., Dhahri, D., Ichimura, A., Dan, T., Miyata, T., Takeda, K., Sakamoto, K., Hattori, K., and Heissig, B.
FASEB J.   31(6) 2625-2637   2017   [Refereed]
Obara, W., Sato, F., Takeda, K., Kato, R,. Kato, Y,. Kanehira, M,. Takata, R,. Mimata, H, Sugai, T., Nakamura, Y, and Fujioka, T.
Cancer Science   108(7) 1452-1457   2017   [Refereed]
Tumor immunoevasion by conversion of effector NK cells into type 1 innate lymphoid cells.
Gao, Y., Souza-Fonseca-Guimaraes, F., Bald, T., Ng, S. S., Young, A., Ngiow, S. F., Rautela, J., Straub, J., Waddell, N., Blake, S. J., Yan, J., Bartholin, L., Lee, J. S., Vivier, E., Takeda, K., Messaoudene, M., Zitvogel, L., Teng, M. W. L., Belz, G. T., Engwerda, C. R., Huntington, N. D., Nakamura, K., Hölzel, K. M. and Smyth, M. J.
Nature Immunol.   18(9) 1004-1015   2017   [Refereed]
Co-administration of RANKL and CTLA4 antibodies enhances lymphocyte-mediated anti-tumor immunity in mice.
Ahern, E., Harjunpaa, H., Barkauskas, D., Allen, S., Takeda, K., Yagita, H., Wyld, D., Dougall, W. C., Teng, M. W. L., and Smyth, M. J.
Clin. Cancer Res.   23(19) 5789-5801   2017   [Refereed]
Interleukin-12 from CD103+ Batf3-dependent dendritic cells required for NK cell suppression of metastasis.
Mittal, D., Vijayan, D., Putz, E., M., Aguilera, A. R., Markey K. A., Straube, J., Kazakoff, S., Nutt, S. L., Takeda, K., Hill, G. R., Waddell, N., and Smyth, M. J.
Cancer Immunol. Res.   5(12) 1098-1108   2017   [Refereed]
Makino, S., Sato, A., Goto, A., Nakamura, M., Ogawa, M., Chiba, Y., Hemmi, J., Kano, H., Takeda, K., Okumura, K. and Asami, Y.
J. Dairy Science.   99(2) 915-923   2016   [Refereed]
Finnberg, N. K., Gokare, P., Navaraj, A., Lang Luhs K. A., Cerniglia, G., Yagita, H., Takeda, K., Motoyama, N., and EL-Deiry, W. S.
Cancer Res.   76(3) 700-712   2016   [Refereed]
Blake, S. J., Stannard, K., Liu, J., Allen, S., Yong, M. C., Mittal, D., Aguilera, A. R., Miles, J. J., Lutzky, V. P., de Andrade, L. F., Martinet, L., Colonna, M., Takeda, K., Kühnel, F., Gurlevik, E., Bernhardt, G., Teng, M. W., and Smyth, M. J.
Cancer Discov.   6(4) 446-459   2016   [Refereed]
Murahashi, M., Hijikata, Y., Yamada, K., Tanaka, Y., Kishimoto, J., Inoue, H., Marumoto, T., Takahazhi, A., Okazaki, T., Takeda, K., Hirakawa, M., Fujii, H., Okano, S., Morita, M., Baba, E., Mizumoto, K., Maehara, Y., Tanaka, M., Akashi, K., Nakanishi, Y., Yoshida, K., Tsunoda, T., Tamura, K., Nakamura, Y., and Tani, K.
Clin. Immunol.   166-167 48-58   2016   [Refereed]
Young, A., Ngiow, S. F., Barkauskas, D. S., Sult, E., Hay, C., Stephen J. Blake, S. J., Huang, Q., Liu, J., Takeda, K., Teng, M. W. L., Sachsenmeier, K., and Smyth, M. J.
Cancer Cell   30(3) 391-403   2016   [Refereed]
TLiu, J., Blake, S. J., Harjunpaa, H., Fairfax, K. A., Yong, M. C., Allen, S., Kohrt, H. E., Takeda, K., Smyth, M. J., and Teng, M. W. L.
Cancer Res.   76(18) 5288-5301   2016   [Refereed]
Takeda, K., Sasaki, K. and Okumura, K.
Tradit. Kampo Med.   3(2) 100-106   2016   [Refereed]
Liu, J., Blake, S. J., Yong, M. C., Harjunpaa, H., Ngiow, S. F., Takeda, K., Young, A., O’Donell, J. S., Allen, S., Smyth, M.J., and Teng, M. W. L.
Cancer Discov.   6(12) 1382-1399   2016   [Refereed]
Munakata, S., Tashio, Y., Nishida, C., Sato, A., Komiyama, H., Shimazu, H., Dhahi, D., Salama, Y., Eiamboonsert, S., Takeda, K., Yagita, H., Tsuda, Y., Okada, Y., Nakauchi, H., Sakamoto, K., Heissig, B., and Hattori, K.
Gastroenterology   148(3) 565-578   2015   [Refereed]
Hata, R-I., Izukuri K., Kato, Y., Sasaki, S., Mukaida, N., Maehata, Y., Miyamoto, C., Akasaka, T., Yang, X., Nagashima, Y., Takeda, K., Kiyono. T., and Taniguchi, M
Scientific Reports   5 9083   2015   [Refereed]
Souza-Fonseca-Guimaraes, F., Young, A., Mittal, D., Martinet, L., Bruedigam, C., Takeda, K., Degli-Esposti, M., Andoniou, C. E., Hill, G. R. and Smyth, M.J.
Proc. Natl. Acad. Sci. USA.   112(8) E2376-E2384   2015   [Refereed]
Naito, T., Baba, T., Takeda, K., Sasaki, S., Nakamoto, Y. and Mukaida, N.
Cancer Letters   366(1) 93-99   2015   [Refereed]
Guillerey, C., Chow, M. T., Miles, K., Olver, S., Sceneay, J., Takeda, K., Mollere, A. and Smyth, M.J.
OncoImmunology   4(9) e1027468   2015   [Refereed]
Takeda, K. and Okumura, K.
eCAM   2015    2015   [Refereed]
Ferrari de Andrade, L., Ngiow S.F., Stannard, K., Rusakiewicz, S., Kalimutho, M., Khnna, K.K., Tey, S.K., Takeda, K., Zitvogel, L., Martinet, L., and Smyth, M.J.
Cancer Res.   74(24) 7298-7308   2014   [Refereed]
Hosoya, S., Ikejima, K., Takeda, K., Arai, K., Ishikawa, S., Yamagata, H., Aoyama, T., Kon, K., Yamashina, S., and Watanabe, S.
Am. J. Physiol. Gastrointest. Liver Physiol.   304(31) G293-G299   2013   [Refereed]
Matsusita, N., Aruga, A., Inoue, Y., Kotera, Y., Takeda, K., and Yamamoto, M.
Oncol. Rep.   29(3) 951-959   2013   [Refereed]
Takahashi, K., Takeda, K., Saiki, I., Irimura, T., and Hayakawa, Y.
Cancer Sci.   104(5) 558-562   2013   [Refereed]
Aruga, A., Takeshita, N., Kotera, Y., Okuyama, R., Matsushita, N., Ohta, T., Takeda, K., and Yamamoto, M.
Clin. Cancer Res.   19(8) 2224-2231   2013   [Refereed]
Asahara, S., Takeda, K., Yamao. K., Maguchi, H. and Yamaue, H.
J. Transl. Med.   11 291   2013   [Refereed]
Noji, S., Hosoi, A., Takeda, K., Matsushita, H., Morishita, Y., Seto, Y., and Kakimi, K.
J. Immunother.   35(6) 460-172   2012   [Refereed]
Proc. Natl. Acad. Sci. USA.   108(45) 18360-18365   2011   [Refereed]
Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.
Takeda, K., Kojima, Y., Uno, T., Hayakawa, Y., Teng, M. W. L., Yoshizawa, H., Yagita, H., Gejyo, F., Okumura, K., and Smyth, M. J.
J. Immunol.   184(10) 5493-5501   2010   [Refereed]
Blood   113(16) 3812-3830   2009   [Refereed]
Proc. Natl. Acad. Sci. USA.   105(31) 10895-10900   2008   [Refereed]
Interleukin-12 - and IFN-g-mediated netural killer cell activation by Agaricus Blazei Murill.
Yuminamochi, E., Koike, T., Takeda, K., Horiuchi, I., and Okumura, K.
Immunology   121(2) 197-206   2007   [Refereed]
Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human NK-cell activity.
Takeda, K., and Okumura, K.
J. Nutr.   137(3) 791S-793S   2007   [Refereed]
Oncogene   26(25) 3745-3757   2007   [Refereed]
Interleukin-12 is involved in the enhancement of human natural killer cell activity by Lactobacillus casei Shirota.
Takeda, K., Suzuki, T., Shimada, S. _I., Shida, K., Nanno, M, and Okumura, K.
Clin. Exp. Immunol.   146(1) 109-115   2006
Nature Med.   12(6) 693-698   2006   [Refereed]

Misc

 
Requirement of 1L-4 and Lirer NK1+T cells for Concanavalin A-induced nepatic Injury in Mice(共著)
The Journal of Immunology   159(8) 1537   1997
Interlenkir-12 as an inducer of cytotoxic effectors in anti-tumor immunity(共著)
International Review of Immunology   14(1) 229   1997
Cytotoxic γδ or αβ T cells with a natural Killer all marker, CD56, induced from human peripheral blood lymphocytes by a combination of 1L-12 and 1L-2(共著)
The Journal of Immunology   157(10) 3886   1996

Research Grants & Projects

 
Analysis of anti-tumor immunity
Grant-in-Aid for Scientific Research
functin of NK cells
Grant-in-Aid for Scientific Research
function of NK1+T cells
Grant-in-Aid for Scientific Research