Sadao Suga

Profile Information

Affiliation: Professor, Tokyo Dental College Ichikawa Genereal Hospital, Tokyo Dental College

Degree: (BLANK)(Keio University)

J-GLOBAL ID: 200901036615003410
researchmap Member ID: 1000228118

Research Interests

Research Areas

Life sciences / Neurosurgery /

Research History

1990 - 1992

米国々立衛生研究所神経疾患脳卒中研究所研究員
1990 - 1992

National Institutes of Health, NINDS, Guest Researcher

Education

- 1982

School of Medicine, Keio University
- 1982

Faculty of Medicine, Keio University

Committee Memberships

1998

評議員, 日本脳卒中学会
1997

評議員, 日本脳循環代謝学会

Papers

Predicting the overall management outcome in patients with a subarachnoid hemorrhage accompanied by a massive intracerebral or full-packed intraventricular hemorrhage: a 15-year retrospective study

T Nakagawa, S Suga, K Mayanagi, K Akaji, J Inamasu, T Kawase

SURGICAL NEUROLOGY, 63(4) 329-334, Apr, 2005 Peer-reviewed
Effect of intra-ischemic hypothermia on the expression of c-Fos and c-Jun, and DNA binding activity of AP-1 after focal cerebral ischemia in rat brain

K Akaji, S Suga, T Fujino, K Mayanagi, J Inamasu, T Horiguchi, S Sato, T Kawase

BRAIN RESEARCH, 975(1-2) 149-157, Jun, 2003 Peer-reviewed
Neuroprotection role of adenosine under hypothermia in the rat global ischemia involves inhibition of not dopamine release but delayed postischemic hypoperfusion.

Takashi Horiguchi, Katsuyoshi Shimizu, Masahiro Ogino, Noriyuki Yamaguchi, Sadao Suga, Joji Inamasu, Takeshi Kawase

Brain research, 952(2) 222-31, Oct 18, 2002
Transient forebrain ischemia induces expression of serine/threonine protein phosphatase 1 mRNA in the vulnerable regions of gerbil brain

T Horiguchi, H Shima, S Suga, M Ogino, K Shimizu, S Toya, M Nagao, T Kawase

NEUROSCIENCE LETTERS, 325(2) 115-118, Jun, 2002 Peer-reviewed
Surgical Outcome of Subarachnoid Hemorrhage Patients with Ruptured Anterior Communicating Artery Aneurysm: Memory Disturbance and Resumption of Work.

SUGA Sadao, NAKAGAWA Toru, MAYANAGI Keita, KAWASE Takeshi

Nosotchu no Geka Kenkyukai koenshu, 30(4) 258-263, 2002
Cerebral microaneurysms found incidentally during aneurysm surgery

J Inamasu, S Suga, T Horiguchi, K Akaji, K Mayanagi, T Kawase

NEUROLOGICAL RESEARCH, 23(4) 304-308, Jun, 2001 Peer-reviewed
Strategy for Unruptured Intracranial Aneurysms and Rupture Rate of Previously Unruptured Aneurysms in Japan(<Topics>therapeutic Strategy for Unruptured Cerebral Aneurysms)

SUGA Sadao, KAWASE Takeshi, Sadao SUGA, Takeshi KAWASE, Department of Neurosurgery Keio University School of Medicine, Department of Neurosurgery Keio University School of Medicine

Nosotchu no Geka Kenkyukai koenshu, 29(3) 160-165, May 31, 2001
Longitudinal changes of metabolites in frontal lobes after hemorrhagic stroke of basal ganglia: A proton magnetic resonance spectroscopy study

Masahito Kobayashi, Hideichi Takayama, Sadao Suga, Ban Mihara

Stroke, 32(10) 2237-2244, 2001 Peer-reviewed
Evaluation of cerebral metabolism by multivoxel proton magnetic resonance spectroscopy imaging in chronic unilateral internal carotid artery occlusion

Hideichi Takayama, Sadao Suga, Masahito Kobayashi, Fumiko Sadanaga, Akinori Hozumi, Yoshihiro Kanai, Miyuki Okamura, Ban Mihara

Brain and Nerve, 52(4) 307-312, 2000 Peer-reviewed
Effect of intraischemic hypothermia on expression of c-Fos, c-Jun, and HSP72 after transient focal cerebral ischemia in rat brain

K Akaji, S Suga, K Mayanagi, J Inamasu, T Horiguchi, S Sato, T Kawase

BRAIN HYPOTHERMIA: PATHOLOGY, PHARMACOLOGY, AND TREATMENT OF SEVERE BRAIN INJURY, 61-67, 2000 Peer-reviewed
Postischemic hypothermia attenuates apoptotic cell death in transient focal ischemia in rats

J Inamasu, S Suga, S Sato, T Horiguchi, K Akaji, K Mayanagi, T Kawase

BRAIN EDEMA XI, 76 525-527, 2000 Peer-reviewed
SEQUENTIAL CHANGE OF BRAIN EDEMA BY SEMIQUANTITATIVE MEASUREMENT ON MRI IN PATIENTS WITH HYPERTENSIVE INTRACEREBRAL HEMORRHAGE

S SUGA, S SATO, K YUNOKI, B MIHARA

ACTA NEUROCHIRURGICA, 564-567, 1994 Peer-reviewed
PHARMACOLOGY OF THE POSTISCHEMIC STRESS RESPONSE - EFFECTS OF TEMPERATURE ON HSP70 EXPRESSION AFTER TRANSIENT ISCHEMIA AND HYPOTHERMIC ACTION OF NBQX IN THE GERBIL

S SUGA, TS NOWAK

PHARMACOLOGY OF CEREBRAL ISCHEMIA 1992, 279-286, 1992 Peer-reviewed
CHANGES IN GENE-EXPRESSION AFTER TRANSIENT ISCHEMIA AS POTENTIAL MARKERS FOR EXCITOTOXIC PATHOLOGY

TS NOWAK, OC OSBORNE, S SUGA

ROLE OF NEUROTRANSMITTERS IN BRAIN INJURY, 227-232, 1992 Peer-reviewed
Cerebral Hemodynamic Changes Before and After Removal of AVMs

YAZAKI Takahito, SUGA Sadao, TAMURA Kiyotaka, SAITO Ryoichi, KAWASE Takeshi, TOYA Shigeo

Surgery for Cerebral Stroke, 18(3) 263-266, 1990

Misc.

Acute subdural hematoma caused by ruptured cerebral aneurysms: diagnostic and therapeutic pitfalls

J Inamasu, R Saito, Y Nakamura, K Ichikizaki, S Suga, T Kawase, S Hori, N Aikawa

RESUSCITATION, 52(1) 71-76, Jan, 2002
Intra-ischemic hypothermia attenuates intercellular adhesion molecule-1 (ICAM-1) and migration of neutrophil

J Inamasu, S Suga, S Sato, T Horiguchi, K Akaji, K Mayanagi, T Kawase

NEUROLOGICAL RESEARCH, 23(1) 105-111, Jan, 2001
Post-ischemic hypothermia delayed neutrophil accumulation and microglial activation following transient focal ischemia in rats

J Inamasu, S Suga, S Sato, T Horiguchi, K Akaji, K Mayanagi, T Kawase

JOURNAL OF NEUROIMMUNOLOGY, 109(2) 66-74, Sep, 2000
Long-term outcome of 17 cases of large-giant posterior fossa aneurysm

J Inamasu, S Suga, S Sato, S Onozuka, T Kawase

CLINICAL NEUROLOGY AND NEUROSURGERY, 102(2) 65-71, Jun, 2000
未破裂脳動脈瘤術前後の大脳半球の脳代謝および高次脳機能の変化-1H-MR spectroscopyおよびWAIS-Rを用いた検討-(共著)

脳神経外科, 28(8) 691-698, 2000
内頚動脈閉塞症慢性期の1H-MRSによる脳代謝分析(共著)

脳と神経, 52(4) 307-312, 2000
CT Scans Essential After Posttraumatic Loss of Consciousness(共著)

Am J Emerg Med, 18 810-811, 2000
A 35-year-old man with cerebral hemorrhage and pheochromocytoma : the second brain-dead organ donor in Japan(共著)

Keio J Med, 49(3) 117-130, 2000
Basilar artery occlusion caused by mucormycotic emboli, preceded by acute hydro cephalus

Clinical Neurology and Neurosurgery, 102 18-22, 2000
Cerebral hemorrhage. Serial study using diffusion-weighted MRI.

Takayama Hideichi, Kobayashi Masahito, Suga Sadao, Sadanaga Fumiko, Mihara Ban

Jpn. J. Stroke, 21(2) 245-252, 1999
Diffusion-weighted MRI による急性期脳梗塞の診断

CI 研究, 21(1) 25-31, 1999
くも膜下出血後の脳血管攣縮による二次的脳梗塞は予測も予防も困難?

総合リハビリテーション, 27 79-82, 1999
Cerebral Hemorrhage : Serial study using diffusion- weighted MRI

Hideichi Takayama, Masahito Kobayashi, Sadao Suga, Fumiko Sadanaga, Ban Mihara

Jpn J Stroke, 21(2) 245-252, 1999
Diffusion-weighted MRI in Acute Cerebral Stroke

Progress in Computed Imaging, 21(1) 25-31, 1999
How to monitor or treat secondary cerebral infarction due to vasospasm after subarachnoid hemorrhage?

27 79-82, 1999
Aneurysm of the ophthalmic artery trunk

S Sato, S Suga, T Ohira, H Takayama, T Kawase

ACTA NEUROCHIRURGICA, 141(3) 321-322, 1999
Moderate hypothermia in patients with subarachnoid hemorrhage : Analysis of that efficacys and problems

27 266-266, Jun 24, 1998
Vascular reconstruction surgery for the progressive stroke patient

27 346-346, Jun 24, 1998
Clinical features and surgery of distal anterior cerebral artery aneurysm

27 237-237, Jun 24, 1998
Postischemic hyperthermia increases expression of hsp72 mRNA after brief ischemia in the gerbil

S Suga, TS Nowak

NEUROSCIENCE LETTERS, 243(1-3) 57-60, Feb, 1998

Books and Other Publications

破裂脳動脈瘤重症例の治療(共著)

2000
Effect of Intraischemic Hypothermia on Intercellular Adhesion Molecule-1 and Migration of Neutrophils(共著)

Ischemic Blood Flow in the Brain, 2000
Effect of Intraischemic Hypotherrmia on Expression of c-Fos, c-Jun and HSP72 After Transient Focal Cerebral Ischemia in Rat Brain(共著)

Brain Hypothermia, 2000
脳虚血におけるWater channel mRNAの発現

1999
Water channel mRNA expression following cerebral ischemia

Progress in Research on Brain Edema and ICP, 1999
ラット脳局所虚血-再潅流モデルにおける虚血後長期低体温の脳保護効果についての考察

虚血性神経細胞死,サイメッド・パブリケーションズ, 1998
Evaluation of Neuroprotective Effect of Post-ischemic Hypothermia Using Transient Focal Ischemia Model in Rats

Ischemic Neuronal Death, 1998
脳虚血と遺伝子発現

神経1997、中外医学社, 1997
Cerebral ischemia and gene expression

Annual Review, 1997
高血圧性脳出血に伴う脳浮腫-MRI,mapping EEG,SEPによる経時的検討-

第17回脳浮腫研究会報告集, 1994
The Heat Shock Response and Gene Expression in Brain after Ischaemia

Heat Shock Proteins in the Nervous System, Academic Press, 1994
Brain edema caused by intracerebralhem orrhage

1994
脳出血患者における脳浮腫の定量的経時的検討

第15回脳浮腫研究会報告集, 1992
Sequential Change of Brain Edaeme by Semiquantitative Measurement on MRI in Patients with Hypertensive Intracerebral Hemorrhage

1992
Adequate Rate of Xenon Inhalation in the End-Tidal Gas-Sampling Method

Cerebral Blood Flow Measurement with Stable Xenon-Enhanced Computed Tomography, Raven Press, 1992
Effects of Temperature on Hsp70 Expression after Transient Ischemia and Hypothermic Action of NBQX in the Gerbil

Pharmacology of Cerebral Ischemia, Wissenschaftliche Verlagsgesellschaft mbH, 1992

Professional Memberships

Research Projects

選択的脳分離循環を用いた脳低温療法による虚血再灌流障害の予防と脳保護効果

科学研究費助成事業, 基盤研究(C), 日本学術振興会, 2002 - 2004

菅貞郎, 中川亨
Brain protection for ischemic insult by the drug induced heat shock protein

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2000 - 2001

SUGA Sadao, MAYANAGI Keita, AKAJI Kazunori
嚥下障害に対する圧センサーを用いた新しい検査法とバイオフィードバック訓練法の開発

科学研究費助成事業, 一般研究(C), 日本学術振興会, 1994 - 1995

美原盤, 井桁之総, 菅貞郎, 柚木和太
遅発性神経細胞死と低体温の保護作用.-虚血後の遺伝子発想からみた検討-

科学研究費助成事業, 一般研究(C), 日本学術振興会, 1994 - 1995

菅貞郎, 井桁之総, 美原盤, 野田幸男, 柚木和太, 佐藤周三
経頭蓋磁気刺激による急性期脳卒中患者の運動機能評価と予後判定

科学研究費助成事業, 奨励研究(A), 日本学術振興会, 1993 - 1993

菅貞郎
選択的脳低温法の開発
¹H-MRSを用いた脳温測定
脳虚血に対する低体温の保護作用の研究-遺伝子発現からの検討-
brain ischemia
Selective brain cooling method
In vivo measurement of brain temperature by ¹H-MRS
Mechanism of Protective Effect of Hypothermia on Cerebral Ischemia-Effect of Gene Expression-

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Papers

Misc.

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