小林孝志 (Takashi Kobayashi) - マイポータル

基本情報

所属: 帝京大学医学部ちば総合医療センター皮膚科准教授

学位: 博士(医学)(慶應義塾大学)

J-GLOBAL ID: 200901079917934634
researchmap会員ID: 1000284691

研究キーワード

研究分野

ライフサイエンス / 皮膚科学 /

学歴

委員歴

2001年

日本結合組織学会, 評議員

論文

Giant vascular eccrine spiradenoma mimicking calcifying epithelioma

Asako Hatano, Takashi Kobayashi, Satoshi Fukuzumi, Yusuke Shirakashi, Chihiro Nishimura, Hiroko Gomi, Hajime Saiga, Kazuhito Hayakawa

JOURNAL OF DERMATOLOGY 40(10) 853-854 2013年10月査読有り
Increased Expression of Gelatinase and Caspase Activities in the Skin of NC/Tnd Mice: A Model for Atopic Dermatitis

Takashi Kobayashi, Kazuhito Hayakawa, Akane Tanaka, Hiroshi Matsuda

DERMATITIS 24(5) 254-255 2013年9月査読有り
Bullous pyoderma gangrenosum: A case report and review of the published work

Masayuki Sakiyama, Takashi Kobayashi, Yuiko Nagata, Norihiro Fujimoto, Takahiro Satoh, Shingo Tajima

JOURNAL OF DERMATOLOGY 39(12) 1010-1015 2012年12月査読有り
Two cases of erythema exsudativum multiforme associated with Chlamydia pneumoniae infection

Ryoko Hosokawa, Takashi Kobayashi, Toshihide Higashino, Chika Asano, Koji Ono, Norihiro Fujimoto, Shingo Tajima

JOURNAL OF DERMATOLOGY 39(3) 306-308 2012年3月査読有り
Suppression of matrix metalloproteinase-9 expression in undifferentiated, non-apoptotic keratinocytes is abrogated by the cleavage of poly(ADP-ribose) polymerase-1

Takashi Kobayashi

APOPTOSIS 16(12) 1205-1216 2011年12月査読有り
Anti-inflammatory treatment for contact dermatitis by topical leptomycin B: Inhibitory effects on the induced expression of matrix metalloproteinases (MMP)-9 and-3

Takashi Kobayashi

EUROPEAN JOURNAL OF DERMATOLOGY 21(3) 438-439 2011年5月査読有り
Is matrix metalloproteinase-9 a culprit involved in dermatitis? Increased expression of gelatinolytic activity in allergic contact dermatitis

Takashi Kobayashi

CONTACT DERMATITIS 64(3) 171-172 2011年査読有り
Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts

Hiroki Ohara, Satomi Ichikawa, Hitoshi Matsumoto, Minoru Akiyama, Norihiro Fujimoto, Takashi Kobayashi, Shingo Tajima

JOURNAL OF DERMATOLOGY 37(4) 330-338 2010年4月査読有り
AGE-Modified Collagens I and III Induce Keratinocyte Terminal Differentiation through AGE Receptor CD36: Epidermal-Dermal Interaction in Acquired Perforating Dermatosis

Eita Fujimoto, Takashi Kobayashi, Norihiro Fujimoto, Minoru Akiyama, Shingo Tajima, Ryoji Nagai

JOURNAL OF INVESTIGATIVE DERMATOLOGY 130(2) 405-414 2010年2月査読有り
Angiosarcoma of the scalp with metastasis to the gingiva

Kenichi Tanabe, Mikio Masuzawa, Ryouichi Aki, Mamiko Masuzawa, Satoru Arai, Kazushige Hayakawa, Kensei Katsuoka, Takashi Kobayashi

ACTA DERMATO-VENEREOLOGICA 88(5) 512-513 2008年査読有り
Neurofibromatosis type 2 in an infant with multiple plexiform schwannomas as first symptom

Takehiko Miyakawa, Noriaki Kamada, Takashi Kobayashi, Keiko Hirano, Katsunori Fujii, Yoshitaro Sasahara, Yuichiro Nagai, Hiroshi Shinkai

JOURNAL OF DERMATOLOGY 34(1) 60-64 2007年1月査読有り
Keratinocyte apoptosis on type I collagen fibrils is prevented by Erk1/2 activation under high calcium condition

Hitomi Fujisaki, Tetsuya Ebihara, Shinkichi Irie, Takashi Kobayashi, Eijiro Adachi, Katumi Mochitate, Shunji Hattori

CONNECTIVE TISSUE RESEARCH 48(3) 159-169 2007年査読有り
Leptomycin B reduces matrix metalloproteinase-9 expression and suppresses cutaneous inflammation

T Kobayashi, H Shinkai

JOURNAL OF INVESTIGATIVE DERMATOLOGY 124(2) 331-337 2005年2月査読有り
Laminin alpha 3 LG4 module induces keratinocyte migration: Involvement of matrix metalloproteinase-9

Y Momota, N Suzuki, Y Kasuya, T Kobayashi, M Mizoguchi, F Yokoyama, M Nomizu, H Shinkai, T Iwasaki, A Utani

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION 25(1) 1-17 2005年査読有り
Matrix metalloproteinase-9 expression is coordinately modulated by the KRE-M9 and TPA responsive elements.

J Invest Dermatol 122, 278-285 2004年
Induction of matrix metalloproteinase-9 secretion from human keratinocytes in culture by ultraviolet B irradiation

S Onoue, T Kobayashi, Y Takemoto, Sasaki, I, H Shinkai

JOURNAL OF DERMATOLOGICAL SCIENCE 33(2) 105-111 2003年11月
Matrix metalloproteinases-2 and -9 are secreted from human fibroblasts.

Acta Derm Venereol 83, 105-107 2003年
In situ detection of gelatinolytic activity in skin specimens of squamous cell carcinoma: Probable role in dyskeratosis and tumor invasion

T Kobayashi

DERMATOLOGY 206(3) 281-283 2003年
Systematic separation and purification of elastase, gelatinase (matrix metalloproteinase 9), and collagenase (matrix metalloproteinase 8) from polymorphonuclear leukocytes in dialyzers previously used by patients with renal failure

T Kobayashi, T Nishikawa, S Hattori, N Yoshida, T Takagi, H Watanabe, H Hori, Y Nagai

PROTEIN EXPRESSION AND PURIFICATION 22(1) 45-51 2001年6月
A novel mechanism of matrix metalloproteinase 9 gene expression implies a role for keratinization

EMBO Rep 2, 604-608 2001年

もっとみる

MISC

Leptomycin B reduces MMP-9 expression and suppresses cutasneous inflammation.

J Invest Dermatol (accepted for publication) 2005年
Matrix metalloproteinase-9 expression is coordinately modulated by the KRE-M9 and TPA responsive elements.

J Invest Dermatol 122, 278-285 2004年
Induction of matrix metalloproteinase-9 secretion from human keratinocytes in culture by ultraviolet B irradiation

S Onoue, T Kobayashi, Y Takemoto, Sasaki, I, H Shinkai

JOURNAL OF DERMATOLOGICAL SCIENCE 33(2) 105-111 2003年11月
In situ detection of gelatinolytic activity in skin specimens of squamous cell carcinoma: Probable role in dyskeratosis and tumor invasion [2]

Takashi Kobayashi

Dermatology 206(3) 281-283 2003年
Matrix metalloproteinases-2 and -9 are secreted from human fibroblasts.

Acta Derm Venereol7 83, 105-107 2003年
Systematic separation and purification of elastase, gelatinase (matrix metalloproteinase 9), and collagenase (matrix metalloproteinase 8) from polymorphonuclear leukocytes in dialyzers previously used by patients with renal failure

T Kobayashi, T Nishikawa, S Hattori, N Yoshida, T Takagi, H Watanabe, H Hori, Y Nagai

PROTEIN EXPRESSION AND PURIFICATION 22(1) 45-51 2001年6月
A novel mechanism of matrix metalloproteinase 9 gene expression implies a role for keratinization

EMBO Rep 2, 604-608 2001年
Differential Regulation of the Secretions of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinases-1 from Human Keratinocytes in Culture.(共著)

IUBMB Life 50(3) 221-226 2000年
Differential Regulation of MMP-2 and MMP-9 Gelatinases in Cultured Human Keratinocytes. (共著)

Dermatology 197 1 1998年
A Case of Angioderatoma Circumscriptum : Immunolocalization of Matrix Metalloproteinase(MMP)-9. (共著)

J Dermatol 25 391 1998年
Acase of linear IgA disease: An immunofluorescent study using confocal laser scan microscopy.

J Dermatol. 24, 306-309 1997年
Secretion of Different Types of Gelatinases from Cultured Human Keratinocytes. (共著)

J Dermatol 24 213 1997年
Diabetic scleredema: A case report and biochemical analysis for glycosaminoglycans

Takashi Kobayashi, Yuichiro Yamasaki, Tomoo Watanabe

Journal of Dermatology 24(2) 100-103 1997年
Immunalocalizations of Human Gelatinase (Type (]G0004[) Collagenase, MMP-9) and TIMP (Tissue Inhibitor of Metalloproteinases) in Hailey-Hailey and Darier's Diseases. (共著)

Dermatology 193 110 1996年
Immunolocalizations of Human Gelatinase(Type (]G0004[) Collagenase, MMP-9) and TIMP(Tissue Inhibitor of Metalloproteinases)in Normal Epidermis and Some Epidermal Tumors, (共著)

Arch Dermatol Res 288 239 1996年
A Novel Gelatinolytic Enzyme Secreted by Amelanotic Cells Isolated from B16 Melanoma Cell Line. (共著)

Cancer Lett 85 165 1994年
A Case of Anaphylactoid Purpura with Multiple Blister Formation : Possible Pathophysiolosical Role of Gelatinase(MMP-9). (共著)

Dermatology 197 62 1993年
Monoclonal Antibodies to Human Ploymorphonuclear Lenkocyte Gelatinase (Type (]G0004[) Collagenase) Are Cross-Reactive with Fibroblast Gelatinase (共著)

Biochem Biophys Res Commun 193(2) 490-496 1993年
Fibroblast and Connective Tissue Metabolism.

Rinsho Derma (Tokyo) (in Japanese) 35, 1261-1275 1993年

書籍等出版物

MMP-9 and TIMP-1 assays in keratinocyte cultures.

Humana Press Epidermal cells: Methods in Molecular Biology 2004年
MMP-9 and TIMP-1 assays in keratinocyte cultures. Humana Press Epidermal cells: Methods in Molecular Biology

Humana Press Epidermal cells: Methods in Molecular Biology 2004年
真皮結合組織代謝異常線維成分異常

中山書店最新皮膚科学大系第10巻 2003年
Abnormal metabolism in the dermis: Fibrillar componentss

Nakayama shoten Saishin-hifukagaku-taikei Vol. 10 (in Japanese) 2003年

小林孝志

基本情報

研究キーワード

研究分野

学歴

委員歴

論文

MISC

書籍等出版物

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

メニュー