MISC

2018年6月27日

Stellatolide H, a cytotoxic peptide lactone from a deep-sea sponge Discodermia sp.

Tetrahedron Letters
  • Shohei Nakamukai
  • ,
  • Kentaro Takada
  • ,
  • Kazuo Furihata
  • ,
  • Yuji Ise
  • ,
  • Shigeru Okada
  • ,
  • Yasuhiro Morii
  • ,
  • Nobuhiro Yamawaki
  • ,
  • Tomohiro Takatani
  • ,
  • Osamu Arakawa
  • ,
  • Kirk R. Gustafson
  • ,
  • Shigeki Matsunaga

59
26
開始ページ
2532
終了ページ
2536
DOI
10.1016/j.tetlet.2018.05.033

© 2018 Stellatolide H (1) was isolated from a deep-sea sponge Discodermia sp. as the cytotoxic constituent. The planar structure of 1 was elucidated on the basis of the NMR spectroscopic and mass spectrometric data. The absolute configurations of the constituent amino acid residues were determined by the Marfey's method. Stellatolide H (1) is a peptide lactone of the callipeltin class with its N-terminus blocked by 3-hydroxy-6,8-dimethyldeca-(4Z,6E)-dienoic acid (Hdda).

リンク情報
DOI
https://doi.org/10.1016/j.tetlet.2018.05.033
Scopus
https://www.scopus.com/record/display.uri?eid=2-s2.0-85047346610&origin=inward
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85047346610&origin=inward
Scopus Citedby
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