坂梨まゆ子 (Sakanashi Mayuko) - マイポータル

基本情報

学位: 博士（医学）(2003年3月琉球大学)

J-GLOBAL ID: 200901074440030191
researchmap会員ID: 1000285498

研究キーワード

研究分野

経歴

論文

Phenotypic Characterization of the Endocannabinoid-Degrading Enzyme Alpha/Beta-Hydrolase Domain 6 Knockout Rat.

Katsuhiko Noguchi, Katsumi Kadekawa, Saori Nishijima, Mayuko Sakanashi, Shiho Okitsu-Sakurayama, Sayomi Higa-Nakamine, Hideyuki Yamamoto, Kimio Sugaya

Cannabis and cannabinoid research 7(2) 179-187 2022年4月査読有り
Protective effect of Actinidia arguta in MPTP-induced Parkinson's disease model mice.

Yuki Kitamura, Mayuko Sakanashi, Azuki Ozawa, Yuri Saeki, Ayano Nakamura, Yuiho Hara, Ken-Ichi Saeki, Sakae Arimoto-Kobayashi

Biochemical and biophysical research communications 555 154-159 2021年5月28日査読有り
Idarubicin, an Anthracycline, Induces Oxidative DNA Damage in the Presence of Copper (II).

Hideki Mizutani, Chiaki Shiga, Masanori Imai, Kenji Ikemura, Yuki Kitamura, Kinya Ohta, Daisuke Miyazawa, Mayuko Sakanashi, Tomoko Tahira, Tohru Maeda …

Anticancer research 40(10) 5399-5404 2020年10月査読有り
Evaluation of a rat model of functional urinary bladder outlet obstruction produced by chronic inhibition of nitric oxide synthase.

Katsuhiko Noguchi, Kimio Sugaya, Saori Nishijima, Mayuko Sakanashi, Katsumi Kadekawa, Katsuhiro Ashitomi, Shiho Okitsu, Hideyuki Yamamoto

Life sciences 234 116772-116772 2019年10月1日査読有り
Protective Role of Myelocytic Nitric Oxide Synthases against Hypoxic Pulmonary Hypertension in Mice.

Takaaki Ogoshi, Masato Tsutsui, Takashi Kido, Mayuko Sakanashi, Keisuke Naito, Keishi Oda, Hiroshi Ishimoto, Sohsuke Yamada, Ke-Yong Wang, Yumiko Toyohira …

American journal of respiratory and critical care medicine 198(2) 232-244 2018年7月15日査読有り
硝酸塩/亜硝酸塩の不足は代謝症候群、血管不全、心臓突然死を惹起する

筒井正人, 喜名美香, 坂梨まゆ子, 松崎俊博, 仲宗根淳子, 佐藤公雄, 下川宏明, 新崎章

血管 41(1) 41-41 2018年1月
[Long-term dietary nitrite and nitrate deficiency causes metabolic syndrome, endothelial dysfunction, and cardiovascular death in mice].

Mika Kina-Tanada, Mayuko Sakanashi, Akira Arasaki, Masato Tsutsui

Nihon yakurigaku zasshi. Folia pharmacologica Japonica 151(4) 148-154 2018年
Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice.

Mika Kina-Tanada, Mayuko Sakanashi, Akihide Tanimoto, Tadashi Kaname, Toshihiro Matsuzaki, Katsuhiko Noguchi, Taro Uchida, Junko Nakasone, Chisayo Kozuka, Masayoshi Ishida …

Diabetologia 60(6) 1138-1151 2017年6月査読有り
Effect of caffeine contained in a cup of coffee on microvascular function in healthy subjects.

Katsuhiko Noguchi, Toshihiro Matsuzaki, Mayuko Sakanashi, Naobumi Hamadate, Taro Uchida, Mika Kina-Tanada, Haruaki Kubota, Junko Nakasone, Matao Sakanashi, Shinichiro Ueda …

Journal of pharmacological sciences 127(2) 217-22 2015年2月査読有り
Development of an experimentally useful model of acute myocardial infarction: 2/3 nephrectomized triple nitric oxide synthases-deficient mouse.

Taro Uchida, Yumi Furuno, Akihide Tanimoto, Yumiko Toyohira, Kumiko Arakaki, Mika Kina-Tanada, Haruaki Kubota, Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi …

Journal of molecular and cellular cardiology 77 29-41 2014年12月査読有り
Long-term treatment with san'o-shashin-to, a kampo medicine, markedly ameliorates cardiac ischemia-reperfusion injury in ovariectomized rats via the redox-dependent mechanism.

Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi, Junko Nakasone, Makiko Sakanashi, Taro Uchida, Mika Kina-Tanada, Haruaki Kubota, Kumiko Arakaki, Akihide Tanimoto …

Circulation journal : official journal of the Japanese Circulation Society 77(7) 1827-37 2013年査読有り
Crucial vasculoprotective role of the whole nitric oxide synthase system in vascular lesion formation in mice: Involvement of bone marrow-derived cells.

Yumi Furuno, Tsuyoshi Morishita, Yumiko Toyohira, Sohsuke Yamada, Susumu Ueno, Naoya Morisada, Kazunari Sugita, Katsuhiko Noguchi, Mayuko Sakanashi, Hironori Miyata …

Nitric oxide : biology and chemistry 25(3) 350-9 2011年10月30日査読有り
Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo.

Katsuhiko Noguchi, Naobumi Hamadate, Toshihiro Matsuzaki, Mayuko Sakanashi, Junko Nakasone, Taro Uchida, Kumiko Arakaki, Haruaki Kubota, Shogo Ishiuchi, Hiroaki Masuzaki …

American journal of physiology. Heart and circulatory physiology 301(3) H721-9 2011年9月査読有り
Improvement of impaired endothelial function by tetrahydrobiopterin in stroke-prone spontaneously hypertensive rats.

Katsuhiko Noguchi, Naobumi Hamadate, Toshihiro Matsuzaki, Mayuko Sakanashi, Junko Nakasone, Makiko Sakanashi, Masato Tsutsui, Matao Sakanashi

European journal of pharmacology 631(1-3) 28-35 2010年4月10日査読有り
Complete disruption of all nitric oxide synthase genes causes markedly accelerated renal lesion formation following unilateral ureteral obstruction in mice in vivo.

Naoya Morisada, Masayoshi Nomura, Hisae Nishii, Yumi Furuno, Mayuko Sakanashi, Ken Sabanai, Yumiko Toyohira, Susumu Ueno, Seiji Watanabe, Masahito Tamura …

Journal of pharmacological sciences 114(4) 379-89 2010年査読有り
Uneven changes in circulating blood cell counts with adrenergic stimulation to the canine spleen

Yoshihiko Ojiri, Katsuhiko Noguchi, Noboru Shiroma, Toshihiro Matsuzaki, Mayuko Sakanashi, Matao Sakanashi

Clinical and Experimental Pharmacology and Physiology 29(1-2) 53-59 2002年
β-Adrenoceptor blocking activities of nipradilol and its optical isomers in pig coronary artery

Tatsushi Itomine, Toshihiro Matsuzaki, Mayuko Sakanashi, Norio Hobara, Matao Sakanashi

Clinical and Experimental Pharmacology and Physiology 28(4) 271-277 2001年

MISC

Hypertension in Mice Lacking 3-Mercaptopyruvate Sulfurtransferase

Masato Tsutsui, Yuichi Totsuka, Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi, Junko Nakasone, Yukio Kuniyoshi

CIRCULATION 134 2016年11月
Hypertension in Mice Lacking 3-Mercaptopyruvate Sulfurtransferase

Yuichi Totsuka, Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi, Yukio Kuniyoshi, Masato Tsutsui

JOURNAL OF VASCULAR RESEARCH 53 64-64 2016年
Complete Disruption of All Nitric Oxide Synthases Markedly Reduces Cerebral Infarct Size After Middle Cerebral Artery Occlusion in Mice

Masato Tsutsui, Kubota Haruaki, Katsuhiko Noguchi, Toshihiro Matsuzaki, Fumiya Hattori, Mayuko Sakanashi, Mika Kina-Tanada, Masayoshi Shift, Junko Nakasone, Hiroaki Shimokawa …

CIRCULATION 132 2015年11月
Long-Term Dietary Nitrite and Nitrate Deficiency Causes Metabolic Syndrome-Like Phenotypes in Mice

Masato Tsutsui, Mika Kina-Tanada, Taro Uchida, Haruaki Kubota, Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi, Junko Nakasone, Yusuke Ohya

CIRCULATION 130 2014年11月
Complete Disruption of All Nitric Oxide Synthase Genes Markedly Reduces Cerebral Infarct Size after Middle Cerebral Artery Occlusion in Mice

Masato Tsutsui, Haruaki Kubota, Katsuhiko Noguchi, Toshihiro Matsuzaki, Fumiya Hattori, Mayuko Sakanashi, Mika Kina-Tanada, Taro Uchida, Junko Nakasone, Hiroaki Shimokawa …

CIRCULATION 130 2014年11月
The cardioprotective effects of San'oshashinto on ischemia/reperfusion injury in ovariectomized rats: involvement of emodin

Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi, Junko Nakasone, Taro Uchida, Mika Kina, Makiko Sakanashi, Haruaki Kubota, Matao Sakanashi, Masato Tsutsui

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 113P-113P 2014年
Development of an Experimentally Useful Model of Spontaneous Myocardial Infarction: 2/3 Nephrectomized Triple Nitric Oxide Synthases-Deficient Mouse

Uchida Taro, Yumi Furuno, Kumiko Arakaki, Mika Kina, Haruaki Kubota, Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi, Junko Nakasone, Yusuke Ohya …

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 88P-88P 2014年
Caffeine Contained in a Cup of Coffee Ameliorates Microvascular Endothelial Function in Healthy Subjects

Masato Tsutsui, Katsuhiko Noguchi, Toshihiro Matsuzaki, Mayuko Sakanashi, Junko Nakasone, Matao Sakanashi, Yusuke Ohya

CIRCULATION 128(22) 2013年11月
Dihydrobiopterin Causes Endothelial Nitric Oxide Synthase Dysfunction in Rats in vivo

Masato Tsutsui, Katsuhiko Noguchi, Toshihiro Matsuzaki, Mayuko Sakanashi, Junko Nakasone, Taro Uchida, Mika Tanada, Haruaki Kubota, Kazuhiro Sugahara, Yusuke Ohya

CIRCULATION 126(21) 2012年11月
San-o-shashinto reduces cardiac ischemia-reperfusion injury in ovariectomized female rats though selective activation of manganese superoxide dismutase

Mayuko Sakanashi, Katsuhiko Noguchi, Toshihiro Matsuzaki, Junko Nakasone, Kumiko Arakaki, Taro Uchida, Makiko Sakanashi, Haruaki Kubota, Mika Tanada, Yusuke Ohya …

JOURNAL OF PHARMACOLOGICAL SCIENCES 118 219P-219P 2012年
Dysfunction of endothelial nitric oxide synthase produced by increasing vascular dihydrobiopterin in rats

Katsuhiko Noguchi, Toshihiro Matsuzaki, Mayuko Sakanashi, Naobumi Hamadate, Junko Nakasone, Kumiko Arakaki, Matao Sakanashi, Masato Tsutsui

JOURNAL OF PHARMACOLOGICAL SCIENCES 118 160P-160P 2012年
Effects of a cup of coffee on peripheral vascular function in healthy subjects

Katsuhiko Noguchi, Toshihiro Matsuzaki, Mayuko Sakanashi, Naobumi Hamadate, Junnko Nakasone, Matao Sakanashi, Masato Tsutsui

JOURNAL OF PHARMACOLOGICAL SCIENCES 115 157P-157P 2011年
Long-term oral administration of San'oshashinto improves vascular endothelial dysfunction and hypercholesterolemia in high fat diet-fed rats

Mayuko Sakanashi, Toshihiro Matsuzaki, Katsuhiko Noguchi, Junko Nakasone, Kumiko Arakaki, Makiko Sakanashi, Haruaki Kubota, Masato Tsutsui

JOURNAL OF PHARMACOLOGICAL SCIENCES 115 280P-280P 2011年
Role of dihydrobiopterin in the regulation of endothelial nitric oxide synthase function

Katsuhiko Noguchi, Toshihiro Matsuzaki, Mayuko Sakanashi, Naobumi Hamadate, Junko Nakasone, Kumiko Chinen, Masato Tsutsui, Matao Sakanashi

JOURNAL OF PHARMACOLOGICAL SCIENCES 112 147P-147P 2010年
San'oshashinto protects the heart against ischemia/reperfusion injury in both ovariectomized and non-ovariectomized female rats

Mayuko Sakanashi, Katsuhiko Noguchi, Toshihiro Matsuzaki, Makiko Sakanashi, Junko Nakasone, Kumiko Arakaki, Matao Sakanashi, Masato Tsutsui

JOURNAL OF PHARMACOLOGICAL SCIENCES 112 169P-169P 2010年
Effects of San'oshashinto on ischemia/reperfusion-induced cardiac dysfunction and serum lipid level in ovariectomized rats

Mayuko Sakanashi, Makiko Sakanashi, Katsuhiko Noguchi, Toshihiro Matsuzaki, Junko Nakasone, Matao Sakanashi

JOURNAL OF PHARMACOLOGICAL SCIENCES 109 228P-228P 2009年
Effect of sepiapterin in combination with methotrexate on endothelium-dependent relaxation of rat isolated aorta

Katsuhiko Noguchi, Toshihiro Matsuzaki, Naobumi Hamadate, Mayuko Sakanashi, Makiko Sakanashi, Junko Nakasone, Matao Sakanashi

JOURNAL OF PHARMACOLOGICAL SCIENCES 109 232P-232P 2009年
Effect of decreased levels of intrinsic tetrahydrobiopterin on endothelial function in anesthetized rats

Naobumi Hamadate, Katsuhiko Noguchi, Mayuko Sakanashi, Toshihiro Matsuzaki, Junko Nakasone, Matao Sakanashi

JOURNAL OF PHARMACOLOGICAL SCIENCES 107(1) 49-56 2008年5月
Effect of decreased levels of intrinsic tetrahydrobiopterin on endothelial function in anesthetized rats.

Naobumi Hamadate, Katsuhiko Noguchi, Mayuko Sakanashi, Toshihiro Matsuzaki, Junko Nakasone, Matao Sakanashi

Journal of pharmacological sciences 107(1) 49-56 2008年5月
Effect of sepiapterin on vascular tetrahydrobiopterin contents and endothelial function in rats pretreated with methotrexate

Katsuhiko Noguchi, Naobumi Hamadate, Toshihiro Matsuzaki, Mayuko Sakanashi, Makiko Sakanashi, Junko Nakasone, Matao Sakanashi

JOURNAL OF PHARMACOLOGICAL SCIENCES 106 219P-219P 2008年

もっとみる

共同研究・競争的資金等の研究課題

男性ホルモン補充に起因する虚血性心血管疾患に対する生体内NO量制御の有用性の検証

日本学術振興会科学研究費助成事業基盤研究(C) 基盤研究(C) 2018年4月 - 2022年3月

坂梨まゆ子, 松崎俊博, 筒井正人
テストステロンによる虚血性心脈管障害の増悪機構の解明

日本学術振興会科学研究費助成事業基盤研究(C) 基盤研究(C) 2015年4月 - 2019年3月

坂梨まゆ子, 松崎俊博, 筒井正人, 野口克彦, 谷本昭英
一酸化窒素合成酵素系完全欠損下の脳梗塞縮小現象と次世代治療確立への応用

日本学術振興会科学研究費助成事業若手研究(B) 若手研究(B) 2015年4月 - 2018年3月

久保田陽秋, 野口克彦, 松崎俊博, 坂梨まゆ子, 筒井正人
食事中の亜硝酸／硝酸の不足にて生じる代謝症候群の分子機構の解明と新規治療法の開発

日本学術振興会科学研究費助成事業研究活動スタート支援研究活動スタート支援 2015年8月 - 2017年3月

喜名美香, 坂梨まゆ子, 要匡, 松崎俊博, 野口克彦, 仲宗根淳子, 平良雄司, 新崎章, 筒井正人
三黄瀉心湯による抗メタボリックシンドローム作用の解明

日本学術振興会科学研究費助成事業基盤研究(C) 基盤研究(C) 2010年4月 - 2014年3月

坂梨まゆ子, 松崎俊博
一酸化窒素合成酵素系の臓器連関における役割に関する基盤的研究

日本学術振興会科学研究費助成事業基盤研究(C) 基盤研究(C) 2011年 - 2013年

筒井正人, 野口克彦, 松崎俊博, 坂梨まゆ子
更年期障害に用いられる漢方薬がエストロゲン減少に起因する心血管系の異常に及ぼす影響

日本学術振興会科学研究費補助金若手研究(B) 2006年 - 2008年

坂梨まゆ子

坂梨まゆ子

基本情報

研究キーワード

研究分野

経歴

論文

MISC

共同研究・競争的資金等の研究課題

メニュー

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