HISANAGA Shin-ichi

J-GLOBAL         Last updated: Dec 8, 2018 at 18:06
 
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Name
HISANAGA Shin-ichi
Affiliation
Tokyo Metropolitan University
Section
Graduate School of Science
Job title
Professor
Degree
Doctor(Science)(The University of Tokyo)

Research Areas

 
 

Academic & Professional Experience

 
1985
 - 
1990
Assistant Professor of Medicine, the University
 
 
   
 
of Tokyo
 
1990
 - 
1997
Associate Professor, Tokyo Institute of
 
 
   
 
Technology
 

Education

 
 
 - 
1982
Graduate School, Division of Natural Science, The University of Tokyo
 
 
   
 
Department of Biophysics and Bio Chemistry, Faculty of Science, The University of Tokyo
 

Published Papers

 
S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy.
Chiku T, Hayashishita M, Saito T, Oka M, Shinno K, Ohtake Y, Shimizu S, Asada A, Hisanaga SI, Iijima KM, Ando K.
Neurobiol Aging   71 255-264   2018   [Refereed]
Potent prion-like behaviors of pathogenic a-synuclein and evaluation of inactivation methods.
Tarutani, A., Murayama, S., Hisanaga, S., Hasegawa, M.
Neuropathol Commun.   6 29   2018   [Refereed]
Isoform-independent and phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.
Tuerde, D., Kimura, T., Miyasaka, T., Furusawa, K., Shimozawa, A., Hasegawa, M., Ando, A., Hisanaga, S.,
J. Biol, Chem   293 1781-1793   2018   [Refereed]
Phospho-tau bar code: analysis of phosphoisotypes of tau and its application to tauopathy.
Kimura, T., Sharma, G., Ishiguro, K., Hisanaga, S.
Fron. Mol. Neurosci.   12, 44   2018   [Refereed]
Ca2+/calmodulin-dependent protein kinase II promotes neurodegeneration caused by tau phosphorylated at Ser262/356 in a transgenic Drosophila model of tauopathy.
Oka M, Fujisaki N, Maruko-Otake A, Ohtake Y, Shimizu S, Saito T, Hisanaga SI, Iijima KM, Ando K
J Biochem.   162 335-342   2017   [Refereed]
In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains.
Krishnankutty, A., Kimura, T., Saito, T., Aoyagi, K., Asada, A., Takahashi, S., Ando, K., Ohara-Imaizumi, M., Ishiguro, K., Hisanaga, S.
Sci. Rep   7 8602   2017   [Refereed]
Cdk5 regulation of the GRAB-mediated Rab8-Rab11 cascade in axon outgrowth.
Furusawa, K., Asada, A., Urrutia, P., Gonzalez-Billault, C., Fukuda, M., Hisanaga, S.
J. Neurosci   37 790-806   2017   [Refereed]
Excess APP O-glycosylation by GalNAc-T6 decreases Aβ production.
Akasaka-Manya, K., Kawamura, M., Tsumoto, H., Saitoh, Y., Shinobu Kitazume, S., Hatsuda, H., Miura, Y., Hisanaga, S., Murayama, S., Hashimoto, Y., Manya, H., Endo, T.
J. Biochem   161 99-111   2017   [Refereed]
Cdk5の多彩な機能—神経細胞から非神経系
斎藤太郎、久永眞市.
89 710-718   2017   [Refereed]
複雑怪奇なリン酸化タンパク質タウのPhos-tag解析
61 49-52   2017

Association Memberships

 
 

Research Grants & Projects

 
Regulation mechanism of CDK5 activation
0085 (Japanese Only)
Project Year: 1992   
Role of phosphorylation of neurofilament
Project Year: 1987   
CdK5 and Alzheimer disease
0085 (Japanese Only)
Project Year: 1995